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公开(公告)号：CA2371645A1
公开(公告)日：2000-11-16
申请号：CA2371645
申请日：2000-04-27
Applicant: BASF AG
Inventor： LUBISCH WILFRIED , MULLER REINHOLD , GRANDEL ROLAND , HOGER THOMAS , KOCK MICHAEL , SCHULT SABINE , HOLZENKAMP UTA
IPC: C07D235/20 , A61K31/415 , A61K31/4184 , A61K31/422 , A61K31/427 , A61K31/437 , A61K31/4439 , A61K31/4709 , A61K31/496 , A61K31/497 , A61P3/10 , A61P9/00 , A61P13/12 , A61P19/02 , A61P25/00 , A61P25/08 , A61P25/10 , A61P25/16 , A61P25/28 , A61P29/00 , A61P31/04 , A61P35/00 , A61P43/00 , C07D235/18 , C07D401/04 , C07D401/14 , C07D403/04 , C07D405/04 , C07D409/04 , C07D413/04 , C07D413/14 , C07D417/04 , C07D471/04 , C07D209/00 , C07D213/00 , C07D235/00
Abstract: The present invention relates to novel benzimidazoles, the production thereo f and the utilisation as inhibitors of the enzyme poly(ADP-ribose)polymerase o r PARP (EC 2.4.2.30) for producing medicaments.
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公开(公告)号：AU679812B2
公开(公告)日：1997-07-10
申请号：AU1067195
申请日：1994-11-26
Applicant: BASF AG
Inventor： STEINER GERD , MUNSCHAUER RAINER , UNGER LILIANE , TESCHENDORF HANS-JURGEN , HOGER THOMAS
IPC: C07D401/04 , A61K31/40 , A61K31/403 , A61K31/44 , A61K31/4427 , A61K31/443 , A61K31/4433 , A61K31/505 , A61P25/00 , A61P25/02 , A61P25/08 , A61P25/18 , A61P25/28 , A61P43/00 , C07D209/02 , C07D209/46 , C07D209/52 , C07D209/90 , C07D209/96 , C07D403/04 , C07D403/06 , C07D405/06 , C07D409/04 , C07D409/06 , C07D413/06 , C07D409/14
Abstract: PCT No. PCT/EP94/03910 Sec. 371 Date Apr. 19, 1996 Sec. 102(e) Date Apr. 19, 1996 PCT Filed Nov. 26, 1994 PCT Pub. No. WO95/15312 PCT Pub. Date Jun. 8, 1995Compounds of the formula I I where the substituents have the meanings given in the description, and their preparation are described. The novel compounds are suitable for the control of diseases.
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公开(公告)号：BR9408246A
公开(公告)日：1997-05-27
申请号：BR9408246
申请日：1994-11-26
Applicant: BASF AG
Inventor： STEINER GERD , MUNSCHAUER RAINER , UNGER LILIANE , TESCHENDORF HANS-JUERGEN , HOGER THOMAS
IPC: A61K31/40 , A61K31/403 , A61K31/404 , A61P21/02 , A61P25/08 , A61P25/20 , A61P25/24 , A61P25/26 , C07D209/14 , C07D209/18 , C07D209/44 , C07D209/52 , C07D487/04 , C07D491/048 , C07D497/04
Abstract: PCT No. PCT/EP94/03913 Sec. 371 Date Jun. 6, 1996 Sec. 102(e) Date Jun. 6, 1996 PCT Filed Nov. 26, 1994 PCT Pub. No. WO95/15327 PCT Pub. Date Jun. 8, 1995Compounds of the formula I I where B, R1, R2, n and A have the meanings given in the description, and their preparation are described. The novel compounds are suitable for the control of diseases.
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公开(公告)号：NO962285L
公开(公告)日：1996-06-03
申请号：NO962285
申请日：1996-06-03
Applicant: BASF AG
Inventor： STEINER GERD , MUNSCHAUER RAINER , UNGER LILIANE , TESCHENDORF HANS-JURGEN , HOGER THOMAS
IPC: C07D401/04 , A61K31/40 , A61K31/403 , A61K31/44 , A61K31/4427 , A61K31/443 , A61K31/4433 , A61K31/505 , A61P25/00 , A61P25/02 , A61P25/08 , A61P25/18 , A61P25/28 , A61P43/00 , C07D209/02 , C07D209/46 , C07D209/52 , C07D209/90 , C07D209/96 , C07D403/04 , C07D403/06 , C07D405/06 , C07D409/04 , C07D409/06 , C07D413/06
Abstract: PCT No. PCT/EP94/03910 Sec. 371 Date Apr. 19, 1996 Sec. 102(e) Date Apr. 19, 1996 PCT Filed Nov. 26, 1994 PCT Pub. No. WO95/15312 PCT Pub. Date Jun. 8, 1995Compounds of the formula I I where the substituents have the meanings given in the description, and their preparation are described. The novel compounds are suitable for the control of diseases.
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公开(公告)号：NO962285A
公开(公告)日：1996-06-03
申请号：NO962285
申请日：1996-06-03
Applicant: BASF AG
Inventor： STEINER GERD , MUNSCHAUER RAINER , UNGER LILIANE , TESCHENDORF HANS-JURGEN , HOGER THOMAS
IPC: C07D401/04 , A61K31/40 , A61K31/403 , A61K31/44 , A61K31/4427 , A61K31/443 , A61K31/4433 , A61K31/505 , A61P25/00 , A61P25/02 , A61P25/08 , A61P25/18 , A61P25/28 , A61P43/00 , C07D209/02 , C07D209/46 , C07D209/52 , C07D403/06 , C07D405/06 , C07D409/04 , C07D409/06 , C07D413/06
CPC classification number: C07D209/52
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Patent Agency Ranking
公开(公告)号：AU3116595A
公开(公告)日：1996-03-04
申请号：AU3116595
申请日：1995-07-22
Applicant: BASF AG
Inventor： STEINER GERD , MUNSCHAUER RAINER , HOGER THOMAS , UNGER LILIANE , TESCHENDORF HANS-JURGEN
IPC: C07D409/12 , A61K31/40 , A61K31/403 , A61P25/18 , A61P43/00 , C07D209/44 , C07D209/52 , C07D209/90 , C07D209/92 , C07D403/06
Abstract: PCT No. PCT/EP95/02912 Sec. 371 Date Feb. 3, 1997 Sec. 102(e) Date Feb. 3, 1997 PCT Filed Jul. 22, 1995 PCT Pub. No. WO96/04245 PCT Pub. Date Feb. 15, 1996A compound of the formula in which A, R1 and n have the meanings stated in the description are described. The novel compounds are suitable for controlling diseases.
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公开(公告)号：SK286676B6
公开(公告)日：2009-03-05
申请号：SK15952001
申请日：2000-05-03
Applicant: BASF AG
Inventor： LUBISCH WILFRIED , SADOWSKI JENS , KOCK MICHAEL , HOGER THOMAS
IPC: C07D237/00 , C07D237/32 , A61K31/00 , A61K31/502 , A61P1/00 , A61P1/10 , A61P9/00 , A61P9/10 , A61P13/00 , A61P13/12 , A61P17/00 , A61P17/02 , A61P19/00 , A61P19/02 , A61P25/00 , A61P25/08 , A61P25/10 , A61P25/12 , A61P25/14 , A61P25/16 , A61P25/28 , A61P29/00 , A61P31/00 , A61P31/04 , A61P35/00 , A61P35/04 , A61P37/00 , A61P41/00 , A61P43/00 , C07D401/00 , C07D401/12 , C07D403/00 , C07D403/12
Abstract: Use of phthalazine derivatives as inhibitors of the enzyme poly(ADP-ribose)polymerase or PARP and their use as inhibitors of PARP-homologous enzymes. These phthalazine derivatives also exhibit in particular a selective inhibition of the PARP-homologous enzymes.
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公开(公告)号：AU764216B2
公开(公告)日：2003-08-14
申请号：AU3034300
申请日：1999-11-23
Applicant: BASF AG
Inventor： LUBISCH WILFRIED , KOCK MICHAEL , HOGER THOMAS , SCHULT SABINE , GRANDEL ROLAND , MULLER REINHOLD
IPC: A61K20060101 , A61K31/4184 , A61K31/454 , A61K31/496 , A61P20060101 , A61P3/12 , A61P9/00 , A61P9/10 , A61P13/12 , A61P17/02 , A61P25/00 , A61P25/08 , A61P25/14 , A61P25/16 , A61P25/28 , A61P29/00 , A61P31/04 , A61P35/00 , A61P43/00 , C07D20060101 , C07D235/30 , C07D401/04 , C07D401/14 , C07D403/04
Abstract: Compounds of the formula Ia or IB where A is a saturated or monounsaturated heterocyclic, 4 - to 8-membered ring which contains one or two nitrogen atoms, and their tautomeric forms, possible enantiomeric and diastereomeric forms, their prodrugs and possible physiologically tolerated salts are useful as inhibitors of the enzyme poly(ADP-ribose)polymerase.
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公开(公告)号：CA2408369A1
公开(公告)日：2002-11-07
申请号：CA2408369
申请日：2001-05-09
Applicant: BASF AG
Inventor： KOCK MICHAEL , GRANDEL ROLAND , LUBISCH WILFRIED , HOLZENKAMP UTA , HOGER THOMAS , SCHULT SABINE , MULLER REINHOLD
IPC: A61K31/404 , A61K31/496 , A61P3/10 , A61P7/00 , A61P9/08 , A61P9/10 , A61P13/12 , A61P19/02 , A61P25/00 , A61P25/08 , A61P25/14 , A61P25/16 , A61P25/28 , A61P29/00 , A61P35/00 , A61P37/02 , A61P43/00 , C07D209/08 , C07D209/12 , C07D209/10 , C07D209/14 , C07D401/04 , C07D403/04 , C07D409/04
Abstract: The invention relates to novel indole derivatives, to the production thereof and to the use thereof as inhibitors of the enzyme poly(ADP ribose)polymeras e or PARP (EC 2.4.2.30) for producing medicaments.
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公开(公告)号：SK15962001A3
公开(公告)日：2002-06-04
申请号：SK15962001
申请日：2000-04-27
Applicant: BASF AG
Inventor： LUBISCH WILFRIED , KOCK MICHAEL , HOGER THOMAS , GRANDEL ROLAND , HOLZENKAMP UTA , SCHULT SABINE , MULLER REINHOLD
IPC: A61K31/415 , A61K31/4184 , A61K31/422 , A61K31/427 , A61K31/437 , A61K31/4439 , A61K31/4709 , A61K31/496 , A61K31/497 , A61P3/10 , A61P9/00 , A61P13/12 , A61P19/02 , A61P25/00 , A61P25/08 , A61P25/10 , A61P25/16 , C07D235/20 , A61P25/28 , A61P29/00 , A61P31/04 , A61P35/00 , A61P43/00 , C07D235/18 , C07D401/04 , C07D401/14 , C07D403/04 , C07D405/04 , C07D409/04 , C07D413/04 , C07D413/14 , C07D417/04 , C07D471/04
Abstract: The present invention relates to novel benzimidazoles, their preparation and their use as inhibitors of the enzyme poly(ADP-ribose) polymerase or PARP (EC 2.4.2.30) for producing drugs.
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