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公开(公告)号：AT196637T
公开(公告)日：2000-10-15
申请号：AT97934552
申请日：1997-07-29
Applicant: BASF AG
Inventor： BAUCKE DORIT , LANGE UDO , MACK HELMUT , PFEIFFER THOMAS , SEITZ WERNER , ZIERKE THOMAS , HOEFFKEN HANS WOLFGANG , HORNBERGER WILFRIED
IPC: A61K31/40 , A61K31/44 , A61K38/00 , A61K38/05 , A61P1/18 , A61P7/02 , A61P11/02 , A61P11/06 , A61P17/00 , A61P19/02 , A61P29/00 , A61P43/00 , C07D207/22 , C07D211/78 , C07K5/00 , C07K5/02 , C07K5/083
Abstract: Compounds of the formula Iwhere R, R1, R2, R3, R4, R5 and R6, and l, m and n have the meanings stated in the description, and their preparation are described. The novel compounds are suitable for controlling diseases.
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公开(公告)号：NO20003814L
公开(公告)日：2000-07-25
申请号：NO20003814
申请日：2000-07-25
Applicant: BASF AG
Inventor： BAUCKE DORIT , LANGE UDO , MACK HELMUT , SEITZ WERNER , HOEFFKEN HANS WOLFGANG , HORNBERGER WILFRIED
IPC: A61K38/00 , A61P1/18 , A61P7/02 , A61P11/06 , A61P17/04 , A61P19/02 , A61P27/16 , A61P29/00 , C07K5/06 , C07K5/065 , C07K5/08 , A61K38/06
Abstract: Novel five-membered heterocyclic amidines, their preparation and use as competitive inhibitors of trypsin-like serine proteases, especially thrombin and kininogenases such as kallikrein. Pharmaceutical compositions which contain the compounds as active ingredients, and use of the compounds as thrombin inhibitors, anticoagulants and antiinflammatory agents.
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公开(公告)号：CZ9900210A3
公开(公告)日：2000-01-12
申请号：CZ21099
申请日：1997-07-14
Applicant: BASF AG
Inventor： MACK HELMUT , PFEIFFER THOMAS , SEITZ WERNER , ZIERKE THOMAS , BALKENHOHL FRIEDHELM , LANGE UDO
IPC: C07D207/22
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公开(公告)号：BR9711191A
公开(公告)日：1999-08-17
申请号：BR9711191
申请日：1997-07-29
Applicant: BASF AG
Inventor： BAUCKE DORIT , LANGE UDO , MACK HELMUT , SEITZ WERNER , ZIERKE THOMAS , HOFFKEN HANS WOLFGANG , HORNBERGER WILFRIED
IPC: A61K38/00 , A61K38/05 , A61P7/02 , A61P29/00 , A61P35/00 , A61P35/04 , C07K5/06 , C07K5/062 , C07K5/065
Abstract: PCT No. PCT/EP97/04104 Sec. 371 Date Feb. 10, 1999 Sec. 102(e) Date Feb. 10, 1999 PCT Filed Jul. 29, 1997 PCT Pub. No. WO98/06741 PCT Pub. Date Feb. 19, 1998Compounds of the formula where A, B, E and D have the meanings indicated in the description, and their preparation are described. The substances are suitable for controlling diseases.
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公开(公告)号：BR9711134A
公开(公告)日：1999-08-17
申请号：BR9711134
申请日：1997-07-29
Applicant: BASF AG
Inventor： BAUCKE DORIT , LANGE UDO , MACK HELMUT , PFEIFFER THOMAS , SEITZ WERNER , ZIERKE THOMAS , HOEFFKEN HANS WOLFGANG , HORNBERGER WILFRIED
IPC: A61K31/40 , A61K31/44 , A61K38/00 , A61K38/05 , A61P1/18 , A61P7/02 , A61P11/02 , A61P11/06 , A61P17/00 , A61P19/02 , A61P29/00 , A61P43/00 , C07D207/22 , C07D211/78 , C07K5/00 , C07K5/02 , C07K5/083 , C07D2
Abstract: Compounds of the formula Iwhere R, R1, R2, R3, R4, R5 and R6, and l, m and n have the meanings stated in the description, and their preparation are described. The novel compounds are suitable for controlling diseases.
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Patent Agency Ranking
公开(公告)号：AU2829799A
公开(公告)日：1999-08-09
申请号：AU2829799
申请日：1999-01-23
Applicant: BASF AG
Inventor： BAUCKE DORIT , LANGE UDO , MACK HELMUT , SEITZ WERNER , HOFFKEN HANS WOLFGANG , HORNBERGER WILFRIED
IPC: A61K38/00 , A61P1/18 , A61P7/02 , A61P11/06 , A61P17/04 , A61P19/02 , A61P27/16 , A61P29/00 , C07K5/06 , C07K5/065 , A61K38/05
Abstract: Novel five-membered heterocyclic amidines, their preparation and use as competitive inhibitors of trypsin-like serine proteases, especially thrombin and kininogenases such as kallikrein. Pharmaceutical compositions which contain the compounds as active ingredients, and use of the compounds as thrombin inhibitors, anticoagulants and antiinflammatory agents.
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公开(公告)号：AU2424499A
公开(公告)日：1999-08-09
申请号：AU2424499
申请日：1999-01-23
Applicant: BASF AG
Inventor： BAUCKE DORIT , LANGE UDO , MACK HELMUT , SEITZ WERNER , HOFFKEN HANS WOLFGANG , HORNBERGER WILFRIED
IPC: A61K38/00 , A61P7/02 , A61P29/00 , A61P43/00 , C07D405/12 , C07D409/12 , C07D417/12 , C07K5/02 , C07K5/06 , C07D205/04
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公开(公告)号：TR199900310T2
公开(公告)日：1999-04-21
申请号：TR9900310
申请日：1997-07-29
Applicant: BASF AG
Inventor： BAUCKE DORIT , LANGE UDO , MACK HELMUT , SEITZ WERNER , ZIERKE THOMAS , HOEFFKEN HANS WOLFGANG , HORNBERGER WILFRIED
IPC: A61K38/00 , A61K38/05 , A61P7/02 , A61P29/00 , A61P35/00 , A61P35/04 , C07K5/06 , C07K5/062 , C07K5/065
Abstract: PCT No. PCT/EP97/04104 Sec. 371 Date Feb. 10, 1999 Sec. 102(e) Date Feb. 10, 1999 PCT Filed Jul. 29, 1997 PCT Pub. No. WO98/06741 PCT Pub. Date Feb. 19, 1998Compounds of the formula where A, B, E and D have the meanings indicated in the description, and their preparation are described. The substances are suitable for controlling diseases.
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公开(公告)号：ZA977240B
公开(公告)日：1999-02-15
申请号：ZA977240
申请日：1997-08-13
Applicant: BASF AG
Inventor： BAUCKE DORIT , LANGE UDO , MACK HELMUT , PFEIFFER THOMAS , SEITZ WERNER , ZIERKE THOMAS , HOEFFKEN HANS WOLFGANG , HORNBERGER WILFRIED
IPC: A61K31/40 , A61K31/44 , A61K38/00 , A61K38/05 , A61P1/18 , A61P7/02 , A61P11/02 , A61P11/06 , A61P17/00 , A61P19/02 , A61P29/00 , A61P43/00 , C07D207/22 , C07D211/78 , C07K5/00 , C07K5/02 , C07K5/083 , C07K , A61K , C07D
Abstract: Compounds of the formula Iwhere R, R1, R2, R3, R4, R5 and R6, and l, m and n have the meanings stated in the description, and their preparation are described. The novel compounds are suitable for controlling diseases.
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公开(公告)号：ID17873A
公开(公告)日：1998-02-05
申请号：ID972839
申请日：1997-08-14
Applicant: BASF AG
Inventor： BAUCKE DORIT , LANGE UDO , MACK HELMUT , SEITZ WERNER , ZIERKE THOMAS , HOFFKEN HANS WOLFGANG , HORNBERGER WILFRIED
IPC: A61K38/00 , A61K38/05 , A61P7/02 , A61P29/00 , A61P35/00 , A61P35/04 , C07K5/06 , C07K5/062 , C07K5/065 , C07D403/00 , C07D407/00 , C07D411/00 , A61K31/33
Abstract: PCT No. PCT/EP97/04104 Sec. 371 Date Feb. 10, 1999 Sec. 102(e) Date Feb. 10, 1999 PCT Filed Jul. 29, 1997 PCT Pub. No. WO98/06741 PCT Pub. Date Feb. 19, 1998Compounds of the formula where A, B, E and D have the meanings indicated in the description, and their preparation are described. The substances are suitable for controlling diseases.
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