公开(公告)号：WO1993012446A1

公开(公告)日：1993-06-24

申请号：PCT/US1992008289

申请日：1992-09-29

Applicant: BAXTER INTERNATIONAL INC.

Inventor： BAXTER INTERNATIONAL INC. ,  SHEARIN, Alan

IPC: G02B06/20

CPC classification number: G02B6/032 ,  A61B18/24 ,  A61B2018/206

Abstract: A light transmitting catheter includes a tube (12) having a proximal end (14) and a distal end (16). The tube (12) contains aqueous fluid. An interior surface on the tube has an index of refraction less than the index of refraction of water. The proximal end (14) is provided with an adapter (18) for receiving light from a light source (20) associated with the proximal end (14) of the tube (12) and with an adapter (24) for accepting an aqueous fluid to be passed throughout a substantial length of the tube (12) for transmitting light to the distal end (16) of the tube (12).

Abstract translation: 透光导管包括具有近端（14）和远端（16）的管（12）。 管（12）含有水性流体。 管上的内表面的折射率小于水的折射率。 近端（14）设置有用于接收来自与管（12）的近端（14）相关联的光源（20）的光的适配器（18）和用于接收含水流体的适配器（24） 通过管（12）的大部分长度以将光传送到管（12）的远端（16）。

公开(公告)号：WO1993011829A1

公开(公告)日：1993-06-24

申请号：PCT/US1992010660

申请日：1992-12-10

Applicant: BAXTER INTERNATIONAL INC. ,  MILLIPORE CORPORATION

Inventor： BAXTER INTERNATIONAL INC. ,  MILLIPORE CORPORATION ,  BUCCHIANERI, Richard ,  DAVIS, Ralph ,  LUEDERS, Arthur ,  SENNINGER, Mark

IPC: A61M39/00

CPC classification number: F16L33/00 ,  A61M1/1656 ,  A61M1/1662 ,  A61M1/1668 ,  A61M1/28 ,  A61M39/18

Abstract: An apparatus and a system are provided for preparing and delivering a peritoneal dialysis solution to a patient under filtered conditions. Means are provided for filtering potable water and mixing it with concentrate solutions under sanitary conditions for delivery through a final sterilizing filter to a patient. An interface apparatus between the patient and the means for making the filtered peritoneal dialysis solution is provided to permit delivery of concentrate solutions for admixture with the filtered water delivery of the dialysis solution to the patient and drainage of the dialysis solution from the patient. Means are also provided for testing the sterility integrity of the system. The interface apparatus permits delivery of a plurality of fluid streams without cross contamination of the fluid streams.

Abstract translation: 提供了一种用于将腹膜透析溶液输送给患者的装置和系统。 包含第一组导管段和包含第二组导管段的装载器的连接器配合在一起，例如配合一组轨道和槽，使得两组导管段形成多个导管，每个导管各自密封 其他管道。 装载机设置有用于以密封的关系将导管段配合在一起的装置，例如偏心安装的可旋转气缸和与气缸接触的压板。 该装置允许将透析溶液递送至患者并随后从患者移除溶液。

公开(公告)号：WO1993011822A1

公开(公告)日：1993-06-24

申请号：PCT/US1992010616

申请日：1992-12-09

Applicant: BAXTER INTERNATIONAL INC.

Inventor： BAXTER INTERNATIONAL INC. ,  SCHIFFER, Michael, C.

IPC: A61M25/01

CPC classification number: A61M25/0169 ,  A61M25/0668 ,  A61M2025/0183 ,  A61M2025/107

Abstract: A rapid exchange over-the-wire catheter is disclosed provided with one or more breakaway elements for progressively exposing the guide wire (18) from the proximal end (24) toward the distal end (26) of the catheter (10) in a simple and efficient manner. The breakaway element may be formed as a longitudinally aligned pull strip (32) provided in the catheter guidewire lumen (30) or as one or more linearly arrayed tubular breakaway segments (52, 54, 56) in the catheter shaft (22) or as a combination of both features.

公开(公告)号：WO1993009821A1

公开(公告)日：1993-05-27

申请号：PCT/US1992009815

申请日：1992-11-12

Applicant: BAXTER INTERNATIONAL INC.

Inventor： BAXTER INTERNATIONAL INC. ,  LINDSAY, Edward, R. ,  KUSMIERCZYK, Robert, C.

IPC: A61M01/16

CPC classification number: A61M1/168 ,  A61M1/1607 ,  A61M1/1662 ,  A61M1/1682 ,  A61M1/1686 ,  A61M1/169

Abstract: An improved chemical treatment system (10) for hemodialysis machines, which includes a first three way valve (26) which has a normally open position in the dialysis and rinsing modes of the hemodialysis machine. The valve in the normally open position couples a source of water (12) through the valve to the bicarbonate pump (66) for rinsing purposes before and after dialysis and the chemical treatment modes of the hemodialysis machine. In the chemical treatment mode of the hemodialysis machine the valve is switched to couple a source (90) of treatment chemical through the valve to the bicarbonate pump. The chemical treatment system includes a second valve (78), which if in the normally open position, then only the bicarbonate portion and associated downstream portions will be chemically treated. In the closed position, the chemical will be switched to also flow through the whole hemodialysis machine from the water inlet to provide for a half or total system chemical treatment cycle. A vent valve (98) coupled to the first valve can be included to further ensure that chemicals are not inadvertently entered into the hemodialysis machine.

公开(公告)号：WO1993008750A2

公开(公告)日：1993-05-13

申请号：PCT/US1992009452

申请日：1992-11-02

Applicant: BAXTER INTERNATIONAL INC.

Inventor： BAXTER INTERNATIONAL INC. ,  NITA, Henry ,  PFLUEGER, Russell

IPC: A61B17/22

CPC classification number: A61B17/22012 ,  A61B2017/22038 ,  A61B2018/00011 ,  A61F2002/30093 ,  A61F2210/0019 ,  A61M2025/0183

Abstract: An ultrasonic ablation device for effecting ultrasonic ablation of intravascular obstructions such as plaque or thrombi. The ultrasonic ablation device has a) an elongate catheter body (12), b) a wave guide or ultrasound transmission wire (20) extending through the elongate catheter body (12), and c) a distal head or probe member (22) positioned at the distal end of the catheter body. A guidewire lumen or passageway (14) extends longitudinally through the catheter body (12) and a guidewire aperture or passageway (60) extends through the distal head or probe (22) such that a guidewire (34) may be passed through the distal head or probe (22) and through the catheter body (12). Also disclosed is an improved distal head or probe which may be incorporated in any elongate ultrasonic ablation device, the improvement comprising the formation of a concavity or indentation in the distal or frontal face (23) of the distal head or probe (22) to improve the cavitation created thereby.

Abstract translation: 超声消融装置用于超声消融血管内障碍物如斑块或血栓。 所述超声波消融装置具有：a）细长的导管主体（12），b）延伸穿过细长导管主体（12）的波导或超声波传输线（20），以及c）远端头部或探针部件 在导管主体的远端处。 导丝管腔或通道（14）纵向延伸穿过导管主体（12），并且导丝孔或通道（60）延伸通过远端头部或探针（22），使得导丝（34）可以穿过远端头部 或探头（22）并穿过导管主体（12）。 还公开了可以结合在任何细长超声波消融装置中的改进的远端头部或探针，改进包括在远端头部或探针（22）的远端或正面（23）中形成凹陷或凹陷以改善 由此产生的气蚀。

公开(公告)号：WO1993003702A1

公开(公告)日：1993-03-04

申请号：PCT/US1992006909

申请日：1992-08-17

Applicant: BAXTER INTERNATIONAL INC.

Inventor： BAXTER INTERNATIONAL INC. ,  STONIS, Thomas, A. ,  PACKARD, Jeffrey ,  FINLEY, Michael ,  ROLLINS, Richard, A.

IPC: A61J01/00

CPC classification number: A61J1/10

Abstract: A cap (34) for providing a tamper evident cover for sealing a portion of an additive port (14), including an injection site (22), of a container (10). The cap (34) comprising first and second halves (36, 38) hinged together along a first edge (40, 42) of each allowing portions of the halves to move towards and away from each other. An interior (50, 52) is defined by the halves for receiving at least a portion of the port (14) and the injection site (22). Members (54, 56) are provided for securing a second edge of the first half to a second edge of the second half. At least one of the first or second halves (36, 38) includes a member (57) circumscribing an interior thereof for causing at least the injection member to be removed upon the application of a sufficient pulling force when the cap is secured to the additive port.

Abstract translation: 一种用于提供用于密封包含容器（10）的注入部位（22）的添加剂端口（14）的一部分的防拆封盖的盖（34）。 包括第一和第二半部（36,38）的盖子（34,38）沿着每个的第一边缘（40,42）铰接在一起，允许半部分的部分朝向和远离彼此移动。 内部（50,52）由用于容纳端口（14）和注射部位（22）的至少一部分的一半限定。 构件（54,56）被设置用于将第一半部的第二边缘固定到第二半部的第二边缘。 第一或第二半部（36,38）中的至少一个包括围绕其内部的构件（57），用于当帽被固定到添加剂时至少引入注射构件以施加足够的拉力时被移除 港口。

公开(公告)号：WO1993001847A1

公开(公告)日：1993-02-04

申请号：PCT/US1992005744

申请日：1992-07-09

Applicant: BAXTER INTERNATIONAL INC.

Inventor： BAXTER INTERNATIONAL INC. ,  RICHARDSON, James ,  LAL, Birendra, K.

IPC: A61M05/14

CPC classification number: A61J1/1406 ,  A61M39/04 ,  A61M2039/0072 ,  A61M2205/197

Abstract: An improvement has been found to the construction of septums used in a variety of medical applications; for example,injection sites (10) typical in intravenous administration sets and blood collection sets and port closures or stoppers in medical containers. The improvement includes a core portion (22) of the septum (16) of sufficient thickness to improve resealability of the septum (16) resulting in an increase duration of the septum (16) without adversely affecting the forces required to insert and remove a needle through the septum (16).

Abstract translation: 已经发现在各种医疗应用中使用的隔膜的构造已经有所改进; 例如，在静脉内给药组中典型的注射部位（10）以及医疗容器中的血液收集装置和封口或塞子。 该改进包括具有足够厚度的隔膜（16）的芯部分（22），以提高隔膜（16）的再密封性，导致隔膜（16）的持续时间增加，而不会不利地影响插入和移除针头所需的力 通过隔膜（16）。

公开(公告)号：WO1992021981A1

公开(公告)日：1992-12-10

申请号：PCT/US1992004432

申请日：1992-05-29

Applicant: BAXTER INTERNATIONAL INC.

Inventor： BAXTER INTERNATIONAL INC. ,  DOBBIE, James, W.

IPC: G01N33/92

CPC classification number: G01N33/6893 ,  G01N33/564 ,  G01N33/92

Abstract: A method for diagnosing inflammatory and degenerative diseases of serous and related tissues is disclosed which involves detecting the presence of antibodies to lamellar bodies, protein constituents of lamellar bodies, or phospholipid constituents of lamellar bodies, whereby the presence of those lamellar bodies or their constituents indicates the occurrence of the disease. Also disclosed are: a method of treating inflammatory and degenerative diseases of serous and related tissues which comprises the step of administering an immune complex consisting of lamellar bodies or their constituents and antibodies specific thereto; a method of treating such diseases by replacing or enhancing lamellar body secretion in body cavities affected by the diseases, or by interfering with an immune reaction associated with the disease; a method of immunizing patients to such disease; and a method of inducing tolerance to lamellar bodies or their constituents. Also disclosed are compositions suitable for use in the disclosed methods, as well as methods for manufacturing the compositions.

Abstract translation: 公开了一种用于诊断浆液性和相关组织的炎性和退行性疾病的方法，其涉及检测层状体的抗体，层状体的蛋白质成分或层状体的磷脂成分的存在，由此，这些层状体或其成分的存在表示 疾病的发生。 还公开了一种治疗浆液性和相关组织的炎性和退行性疾病的方法，其包括施用由层状体或其成分和特异性抗体组成的免疫复合物的步骤; 通过替换或增强受疾病影响的体腔内的层状体分泌物或通过干扰与该疾病相关的免疫反应来治疗这些疾病的方法; 使患者免疫这种疾病的方法; 以及诱导对层状体或其成分的耐受性的方法。 还公开了适用于所公开的方法的组合物以及制备组合物的方法。

公开(公告)号：WO1992021287A1

公开(公告)日：1992-12-10

申请号：PCT/US1992004657

申请日：1992-06-04

Applicant: BAXTER INTERNATIONAL INC.

Inventor： BAXTER INTERNATIONAL INC. ,  TRAUTHEN, Brett

IPC: A61B05/103

CPC classification number: A61B5/1076 ,  G01B3/28

Abstract: A catheter (20) meter is described for determining spacial parameters such as linear distance in a vessel or other body cavity. The cathetermeter (20) includes a catheter having a proximal end (24) and a distal end and a handle (22) for holding the catheter. The catheter further includes a hollow tubular member (34) defining a lumen extending distally of the handle (22) to a catheter tip (40). A wall in the catheter defines a passageway (42) communicating with the lumen for passing a cylindrical member (46) such as a tube or cable having a length and a tip (26) through the passageway (42) and the lumen so that the tip (26) of the cylindrical member (46) can extend distally of the catheter tip (40). A measurement gauge (22) at the proximal end of the catheter is provided for measuring the distance from the proximal end (24) of the catheter to the tip (26) of the cylindrical member (46) when the tip (26) has been passed through the catheter passageway (42) and the lumen and beyond the catheter tip (40).

Abstract translation: 描述了用于确定诸如容器或其他体腔中的线性距离的空间参数的导管（20）计量器。 导管计（20）包括具有近端（24）和远端的导管，以及用于保持导管的手柄（22）。 导管还包括中空管状构件（34），其限定将手柄（22）向远侧延伸到导管尖端（40）的内腔。 导管中的壁限定了与内腔连通的通道（42），用于使具有长度和尖端（26）的管或电缆的圆柱形构件（46）通过通道（42）和内腔，使得 圆柱形构件（46）的尖端（26）可以在导管尖端（40）的远侧延伸。 提供在导管近端处的测量计（22），用于测量当尖端（26）已经被引导时，从导管的近端（24）到圆柱形构件（46）的尖端（26）的距离 穿过导管通道（42）和内腔并超过导管尖端（40）。

公开(公告)号：WO1992019945A1

公开(公告)日：1992-11-12

申请号：PCT/US1992003435

申请日：1992-04-27

Applicant: BAXTER INTERNATIONAL INC.

Inventor： BAXTER INTERNATIONAL INC. ,  SOONG-WU, Su, Syin

IPC: G01K70/22

CPC classification number: H01C17/02 ,  A61B5/028 ,  G01K7/22

Abstract: New thermistor assemblies and methods for making such thermistor assemblies are disclosed. In one embodiment, the present thermistor assembly (10) comprises a thermistor (14) including a thermistor element (20), a protective coating (22) substantially surrounding the thermistor element (20) and electrically conductive lead wires (24, 26) in electrical communication with the thermistor element (20) and extending beyond the protective coating (22); an elongated member (16) including electrically conductive extension wires (28, 30) each of which is bonded to a different one of the lead wires (24, 26) in a bonding zone (36), and an electrically insulating covering (32) located on said extension wires (28, 30) proximal of the bonding zone (36); and an electrically insulating thermally conductive overcoating (18) located over said protective coating (22), lead wires (24, 26) and the bonding zone (36), and being derived from a mixture comprising at least one polymerizable component and at least one thixotropic component.

Abstract translation: 公开了用于制造这种热敏电阻组件的新的热敏电阻组件和方法。 在一个实施例中，本发明的热敏电阻组件（10）包括热敏电阻（14），其包括热敏电阻元件（20），基本上围绕热敏电阻元件（20）的保护涂层（22）和导电引线（24,26） 与热敏电阻元件（20）电连接并延伸超过保护涂层（22）; 包括导电延长线（28,30）的细长构件（16），每个所述导电延伸线在接合区域（36）中接合到不同的引线（24,26），以及电绝缘覆盖物（32） 位于接合区（36）的近侧的所述延伸线（28,30）上; 以及位于所述保护涂层（22），引线（24,26）和接合区（36）之上的电绝缘导热外涂层（18），并且由包含至少一个可聚合组分和至少一个 触变成分。