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公开(公告)号:FR2530023A1
公开(公告)日:1984-01-13
申请号:FR8212005
申请日:1982-07-08
Applicant: COULTER ELECTRONICS
Inventor: BRUNSTING ALBERT , HOGG WALTER R , NEWTON WILLIAM A
Abstract: The invention consists of a particle analysis device. According to the invention, it comprises a reflecting chamber 24 containing an electrolyte having a concave reflecting surface 14 with a first focus 16 and a second focus 18, a drive structure 36 having a tube 38 for directing a flow of particles in suspension in an electrolyte solution, a radiant energy source 26 illuminating the particles when they pass through the first focus to produce a source of detectable radiation signals reflected by the concave surface, an outlet tube 41 in coaxial alignment with the tube 38, a detection aperture 42 at the end of the tube 38 or of the tube 41, and two energised (excited) electrodes in the electrolyte solution on either side of the aperture, which thus creates a restricted electrical path where the flow of particles produces electrical impedance signals. The invention applies especially to electronic and optical measurement particle analysers.
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公开(公告)号:CA1135971A
公开(公告)日:1982-11-23
申请号:CA342923
申请日:1980-01-02
Applicant: COULTER ELECTRONICS
Inventor: BRUNSTING ALBERT , HOGG WALTER R
Abstract: In an apparatus in which particles which may include biological cells are passed through an optical sensing zone to measure their spatial radiant energy distribution for the purpose of identifying and/or characterizing the particles or cells, a structure and method are provided for increasing the usefulness of a geometric configuration of photovoltaic detectors such as a known assembly of generally concentric rings of such detectors usually including some wedge-shaped detectors. These are provided in a generally planar form and the invention provides structure which captures radiant energy in a flow cell of a particular type before projecting the energy to the detector. In particular an ellipsoid, paraboloid, hyperboloid or similar reflector which is symmetrical about its optical axis is utilized first to capture the radiant energy on angles which could include most forward and/or backward angles and all azimuthal angles and then deviating the same to the detector assembly mentioned. By moving the arrangement or assembly of detectors along the optical axis of the reflector the optimum distance is established for obtaining the greatest amount of information sought. Although the assembly of photovoltaic detectors may thereafter be left in place, it is preferred to substitute for said assembly a second highly economical deviating or reflecting device capable of capturing the radiant energy which would otherwise have fallen on the sensitive plane of the assembly of photovoltaic detectors and deviating the same along a plurality of different spaced paths to independent photodetecting devices.
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公开(公告)号:CA1126977A
公开(公告)日:1982-07-06
申请号:CA323102
申请日:1979-03-09
Applicant: COULTER ELECTRONICS
Inventor: HOGG WALTER R , BRUNSTING ALBERT
Abstract: Disclosed is a radiation collector apparatus and method primarily for counting and analyzing a flow of dilute particulate material, such as blood cells, sperm cells and the like, through the use of light detection. The radiation collector apparatus comprises a reflector chamber having an ellipsoidal reflector surface with a pair of ellipsoidal foci defining a first focus, f11, and second focus, f12, and a second reflector surface with a primary focus, f21, positioned at the same point as focus f12, and a secondary focus, f22. The second reflector surface has the configuration of one of the conic sections of revolution. In operation the radiation collector apparatus is provided with an intensifed beam of light and a stream of particulate material aligned to intersect the intensifed beam of light at focus f11. Detectable light signals, after two reflections, are received in a focused beam by a photosensitive detector.
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公开(公告)号:DE3000032A1
公开(公告)日:1980-07-31
申请号:DE3000032
申请日:1980-01-02
Applicant: COULTER ELECTRONICS
Inventor: HOGG WALTER R , BRUNSTING ALBERT
Abstract: In an apparatus in which particles are passed through an optical sensing zone to measure their radiant energy distribution such as, for example, light scattering characteristics for the purpose of identifying the particles, means and a method are provided for deviating the collected light in accordance with predetermined different paths to a plurality of different photodetecting devices. The deviation is effected independently of collection by optical radiant energy transmitting or reflecting means. The different photodetecting devices enable the measurement of energy directed along the particular path which is identified with that device. The paths are established by the deviating means rather than permitted to evolve by the scattering phenomena themselves whereby the photodetecting devices can be located in convenient arrangements and may be conventional in construction. Different forms of the invention combine optical reflection or refraction for collecting the scattered radiant energy with optical reflection or refraction for deviation to achieve different advantages and results.
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公开(公告)号:DE2500528A1
公开(公告)日:1975-09-04
申请号:DE2500528
申请日:1975-01-08
Applicant: COULTER ELECTRONICS
Inventor: HOGG WALTER R
Abstract: A pulse storing and retrieval circuit for storing and recovering serially received pulses to be processed includes a delay line having a plurality of output locations along the length of the line. A first pulse is coupled to the delay line for propagation therethrough and is coupled from the delay line to a pulse processor for processing. Logic circuitry in the pulse storing and retrieval circuit responds to a first signal indicating detection of the pulse by the processor and an indication that processing of the pulse by the pulse processor is in progress to cause the sequential coupling in a first direction of the delay line output locations to the processor as the trailing edge of the pulse propagates down the delay line. Upon indication from the processor that it has finished its processing and a succeeding pulse can be accepted, the logic circuitry begins sequentially coupling each of the output locations of the delay line to the processor in a second direction opposite to the first direction until the leading edge of a succeeding pulse is reached. Upon detection of the succeeding pulse by the pulse processor, the logic circuitry again begins the cycle.
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公开(公告)号:CA1141193A
公开(公告)日:1983-02-15
申请号:CA342924
申请日:1980-01-02
Applicant: COULTER ELECTRONICS
Inventor: HOGG WALTER R , BRUNSTING ALBERT
Abstract: 7,660 APPARATUS AND METHOD FOR MEASURING THE DISTRIBUTION OF RADIANT ENERGY PRODUCED IN PARTICLE INVESTIGATING SYSTEMS In an apparatus in Which particles are passed through an optical sensing zone to measure their radiant energy distribution such as, for example, light scattering characteristics for the purpose of identifying the particles, means and a method are provided for deviating the collected light in accordance with predetermined different paths to a plurality of different photodetecting devices. The deviation is effected independently of collection by optical radiant energy transmitting or reflecting means. The different photodetecting devices enable the measurement of energy directed along the particular path which is identified with that device. The paths are established by the deviating means rather than permitted to evolve by the scattering phenomena themselves whereby the photodetecting devices can be located in convenient arrangements and may be conventional in construction. Different forms of the invention combine optical reflection or refraction for collecting the scattered radiant energy with optical reflection or refraction for deviation to achieve different advantages and results. -1-.
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公开(公告)号:CA1136883A
公开(公告)日:1982-12-07
申请号:CA342921
申请日:1980-01-02
Applicant: COULTER ELECTRONICS
Inventor: HOGG WALTER R
Abstract: METHOD AND APPARATUS FOR MEASUREMENT OF RERADIATION IN PARTICLE FLOW CELL SYSTEMS Measurement of the energy and direction of radiation, typically scattered light, produced by particles passing through an optical sensing zone is improved in focusing of the scattered light and flexibility in the choice of focal length for positioning of photoresponsive devices. The improvement is obtained by collimating the collected scattered light entering a deviating device, typically a prismatic fresnel lens, and then focusing the emerging separate, independent beams for measurement, Collimation can be obtained using optical elements including lens systems or reflective systems such as parabolic reflection.
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公开(公告)号:CA1127241A
公开(公告)日:1982-07-06
申请号:CA337412
申请日:1979-10-11
Applicant: COULTER ELECTRONICS
Inventor: HOGG WALTER R
IPC: G01N15/07
Abstract: A method and apparatus for obtaining information on and identifying particles in a liquid suspension wherein the particles in suspension are moved in a stream through a plurality of sensing zones such that each particle passes through the sensing zones serially. As each particle passes through a sensing zone a particular characteristic of the particle will be measured and its time relationship with the preceding and succeeding particle passing through that zone will also be preserved to form a pattern of time relationships. The pattern of time relationships and the particle characteristics at a particular sensing zone will be correlated with the pattern of time relationships and particle characteristics at either a preceding or succeeding sensing zone in order to correlate all of the characteristics for the particle. The stream may also be passed to a substrate and the particles laid out on the substrate in a particular spatial pattern. The spatial pattern is also correlated with the time relationships and particle characteristics at the last sensing zone preceding the substrate in order to correlate the particle on the substrate with all of its measured characteristics.
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公开(公告)号:DE3000035A1
公开(公告)日:1980-07-31
申请号:DE3000035
申请日:1980-01-02
Applicant: COULTER ELECTRONICS
Inventor: HOGG WALTER R , BRUNSTING ALBERT
Abstract: In an apparatus in which particles are passed through an optical sensing zone to measure their light scattering characteristics for the purpose of identifying the particles, means and a method are provided for deviating the collected light in accordance with predetermined different paths to a plurality of different photodetecting devices. The deviation is effected simultaneously with collection by optical radiant energy reflecting means. The different photodetecting devices enable the measurement of energy scattered along the particular path which is identified with that device. The paths are established by the combined collecting and deviating means rather than permitted to evolve by the scattering phenomena themselves whereby the photodetecting devices can be located in convenient arrangements and may be conventional in construction.
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公开(公告)号:DE3000033A1
公开(公告)日:1980-07-31
申请号:DE3000033
申请日:1980-01-02
Applicant: COULTER ELECTRONICS
Inventor: HOGG WALTER R
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