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公开(公告)号:CH629592A5
公开(公告)日:1982-04-30
申请号:CH254979
申请日:1979-03-19
Applicant: COULTER ELECTRONICS
Inventor: BRUNSTING ALBERT , HOGG WALTER ROBERT
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公开(公告)号:CA1113763A
公开(公告)日:1981-12-08
申请号:CA332658
申请日:1979-07-27
Applicant: COULTER ELECTRONICS
Inventor: BRUNSTING ALBERT , HOGG WALTER R
Abstract: There is disclosed an illuminator and collector apparatus and method for fluorescence analysis wherein illumination of a stream of particles produces fluorescent light. A reflector, having a concave reflector surface with a first focus disposed in the stream of particles, has reflected therefrom organized illuminating radiation, such radiation converging upon the first focus to stimulate the particles into producing the fluorescent light. The fluorescent light emanates from the first focus, a portion of which is reflected from the concave reflector surface. This fluorescent light which is focused on the second focus contains no (or negligible) amount of illuminating radiation and is collected for subsequent detection and processing.
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公开(公告)号:DE3000034A1
公开(公告)日:1980-07-31
申请号:DE3000034
申请日:1980-01-02
Applicant: COULTER ELECTRONICS
Inventor: BRUNSTING ALBERT , HOGG WALTER R
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公开(公告)号:CA1136884A
公开(公告)日:1982-12-07
申请号:CA342922
申请日:1980-01-02
Applicant: COULTER ELECTRONICS
Inventor: HOGG WALTER R , BRUNSTING ALBERT
Abstract: APPARATUS AND METHOD FOR MEASURING SCATTERING OF LIGHT IN PARTICLE DETECTION SYSTEMS In an apparatus in which particles are passed through an optical sensing zone to measure their light scattering characteristics for the purpose of identifying the particles, means and a method are provided for deviating the collected light in accordance with predetermined different paths to a plurality of different photodetecting devices. The deviation is effected simultaneously with collection by optical radiant energy reflecting means. The different photodetecting devices enable the measurement of energy scattered along the particular path which is identified with that device. The paths are established by the combined collecting and deviating means rather than permitted to evolve by the scattering phenomena themselves whereby the photodetecting devices can be located in convenient arrangements and may be conventional in construction.
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公开(公告)号:DE2930593A1
公开(公告)日:1980-02-28
申请号:DE2930593
申请日:1979-07-27
Applicant: COULTER ELECTRONICS
Inventor: BRUNSTING ALBERT , HOGG WALTER R
Abstract: There is disclosed an illuminator and collector apparatus and method for fluorescence analysis wherein illumination of a stream of particles produces fluorescent light. A reflector, having a concave reflector surface with a first focus disposed in the stream of particles, has reflected therefrom organized illuminating radiation, such radiation converging upon the first focus to stimulate the particles into producing the fluorescent light. The fluorescent light emanates from the first focus, a portion of which is reflected from the concave reflector surface. This fluorescent light which is focused on the second focus contains no (or negligible) amount of illuminating radiation and is collected for subsequent detection and processing.
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公开(公告)号:FR2530023A1
公开(公告)日:1984-01-13
申请号:FR8212005
申请日:1982-07-08
Applicant: COULTER ELECTRONICS
Inventor: BRUNSTING ALBERT , HOGG WALTER R , NEWTON WILLIAM A
Abstract: The invention consists of a particle analysis device. According to the invention, it comprises a reflecting chamber 24 containing an electrolyte having a concave reflecting surface 14 with a first focus 16 and a second focus 18, a drive structure 36 having a tube 38 for directing a flow of particles in suspension in an electrolyte solution, a radiant energy source 26 illuminating the particles when they pass through the first focus to produce a source of detectable radiation signals reflected by the concave surface, an outlet tube 41 in coaxial alignment with the tube 38, a detection aperture 42 at the end of the tube 38 or of the tube 41, and two energised (excited) electrodes in the electrolyte solution on either side of the aperture, which thus creates a restricted electrical path where the flow of particles produces electrical impedance signals. The invention applies especially to electronic and optical measurement particle analysers.
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公开(公告)号:CA1135971A
公开(公告)日:1982-11-23
申请号:CA342923
申请日:1980-01-02
Applicant: COULTER ELECTRONICS
Inventor: BRUNSTING ALBERT , HOGG WALTER R
Abstract: In an apparatus in which particles which may include biological cells are passed through an optical sensing zone to measure their spatial radiant energy distribution for the purpose of identifying and/or characterizing the particles or cells, a structure and method are provided for increasing the usefulness of a geometric configuration of photovoltaic detectors such as a known assembly of generally concentric rings of such detectors usually including some wedge-shaped detectors. These are provided in a generally planar form and the invention provides structure which captures radiant energy in a flow cell of a particular type before projecting the energy to the detector. In particular an ellipsoid, paraboloid, hyperboloid or similar reflector which is symmetrical about its optical axis is utilized first to capture the radiant energy on angles which could include most forward and/or backward angles and all azimuthal angles and then deviating the same to the detector assembly mentioned. By moving the arrangement or assembly of detectors along the optical axis of the reflector the optimum distance is established for obtaining the greatest amount of information sought. Although the assembly of photovoltaic detectors may thereafter be left in place, it is preferred to substitute for said assembly a second highly economical deviating or reflecting device capable of capturing the radiant energy which would otherwise have fallen on the sensitive plane of the assembly of photovoltaic detectors and deviating the same along a plurality of different spaced paths to independent photodetecting devices.
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公开(公告)号:CA1126977A
公开(公告)日:1982-07-06
申请号:CA323102
申请日:1979-03-09
Applicant: COULTER ELECTRONICS
Inventor: HOGG WALTER R , BRUNSTING ALBERT
Abstract: Disclosed is a radiation collector apparatus and method primarily for counting and analyzing a flow of dilute particulate material, such as blood cells, sperm cells and the like, through the use of light detection. The radiation collector apparatus comprises a reflector chamber having an ellipsoidal reflector surface with a pair of ellipsoidal foci defining a first focus, f11, and second focus, f12, and a second reflector surface with a primary focus, f21, positioned at the same point as focus f12, and a secondary focus, f22. The second reflector surface has the configuration of one of the conic sections of revolution. In operation the radiation collector apparatus is provided with an intensifed beam of light and a stream of particulate material aligned to intersect the intensifed beam of light at focus f11. Detectable light signals, after two reflections, are received in a focused beam by a photosensitive detector.
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公开(公告)号:DE3000032A1
公开(公告)日:1980-07-31
申请号:DE3000032
申请日:1980-01-02
Applicant: COULTER ELECTRONICS
Inventor: HOGG WALTER R , BRUNSTING ALBERT
Abstract: In an apparatus in which particles are passed through an optical sensing zone to measure their radiant energy distribution such as, for example, light scattering characteristics for the purpose of identifying the particles, means and a method are provided for deviating the collected light in accordance with predetermined different paths to a plurality of different photodetecting devices. The deviation is effected independently of collection by optical radiant energy transmitting or reflecting means. The different photodetecting devices enable the measurement of energy directed along the particular path which is identified with that device. The paths are established by the deviating means rather than permitted to evolve by the scattering phenomena themselves whereby the photodetecting devices can be located in convenient arrangements and may be conventional in construction. Different forms of the invention combine optical reflection or refraction for collecting the scattered radiant energy with optical reflection or refraction for deviation to achieve different advantages and results.
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公开(公告)号:DE2910031A1
公开(公告)日:1979-10-04
申请号:DE2910031
申请日:1979-03-14
Applicant: COULTER ELECTRONICS
Inventor: HOGG WALTER , BRUNSTING ALBERT
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