公开(公告)号：TR199701167T1

公开(公告)日：1998-03-21

申请号：TR9701167

申请日：1996-04-10

Applicant: GLAXO WELLCOME INC

Inventor： ASHURST LAN C ,  HERMAN CRAIG S ,  LI-BOVET LI ,  RIEBE MICHAEL THOMAS

IPC: A61K9/00 ,  A61K9/12 ,  A61K9/72 ,  A61K31/135 ,  A61K31/137 ,  A61K31/57 ,  A61K31/573 ,  A61M15/00 ,  A61P11/08 ,  B05D5/08 ,  B05D7/22 ,  B05D7/24 ,  B65D83/14

Abstract: Metered dose inhaler having all or part of its internal surfaces coated with one or more fluorocarbon polymers, opt. in combination with one or more non-fluorocarbon polymers, is used for dispensing an inhalation drug formulation comprising albuterol (also known as salbutamol) or one of its salts, and a fluorocarbon propellant, opt. in combination with one or more other pharmacologically active agents or one or more excipients. Also claimed is a metered dose inhaler system comprising a metered dose inhaler fitted into a suitable channelling device for oral or nasal inhalation of the drug formulation.

公开(公告)号：CZ325997A3

公开(公告)日：1998-03-18

申请号：CZ325997

申请日：1996-04-10

Applicant: GLAXO WELLCOME INC

Inventor： ASHURST IAN C ,  HERMAN CRAIG S ,  LI-BOVET LI ,  RIEBE MICHAEL T

IPC: A61K9/00 ,  A61K9/12 ,  A61K9/72 ,  A61K31/135 ,  A61K31/137 ,  A61K31/57 ,  A61K31/573 ,  A61M15/00 ,  A61P11/08 ,  B05D5/08 ,  B05D7/22 ,  B05D7/24 ,  B65D83/14

Abstract: Metered dose inhaler having all or part of its internal surfaces coated with one or more fluorocarbon polymers, opt. in combination with one or more non-fluorocarbon polymers, is used for dispensing an inhalation drug formulation comprising albuterol (also known as salbutamol) or one of its salts, and a fluorocarbon propellant, opt. in combination with one or more other pharmacologically active agents or one or more excipients. Also claimed is a metered dose inhaler system comprising a metered dose inhaler fitted into a suitable channelling device for oral or nasal inhalation of the drug formulation.

公开(公告)号：CZ325897A3

公开(公告)日：1998-03-18

申请号：CZ325897

申请日：1996-04-10

Applicant: GLAXO WELLCOME INC

Inventor： ASHURST IAN C ,  HERMAN CRAIG S ,  LI-BOVET LI ,  RIEBE MICHAEL T

IPC: A61K9/12 ,  A61K31/56 ,  A61K31/569 ,  A61M15/00 ,  A61M15/08 ,  A61M16/00 ,  A61P11/00 ,  B05D5/00 ,  B05D5/08 ,  B65D83/14

Abstract: A metered dose inhaler having part or all of its internal surfaces coated with one or more fluorocarbon polymers, optionally in combination with one or more non-fluorocarbon polymers, for dispensing an inhalation drug formulation comprising fluticasone propionate, or a physiologically acceptable solvate thereof, and a fluorocarbon propellant optionally in combination with one or more other pharmacologically active agents or one or more excipients.

公开(公告)号：TR199701170T1

公开(公告)日：1998-02-21

申请号：TR9701170

申请日：1996-04-11

Applicant: GLAXO WELLCOME INC

Inventor： ASHURST IAN C ,  HERMAN CRAIG S ,  LI-BOVET LI ,  RIEBE MICHAEL THOMAS

IPC: B65D83/38 ,  A61K9/00 ,  A61K9/12 ,  A61K9/72 ,  A61K31/137 ,  A61K31/57 ,  A61K31/573 ,  A61M15/00 ,  A61P11/00 ,  B05D5/08 ,  B65D83/14

Abstract: A metered dose inhaler having part or all of its internal surfaces coated with one or more fluorocarbon polymers, optionally in combination with one or more non-fluorocarbon polymers, for dispensing an inhalation drug formulation comprising beclomethasone dipropionate or a physiologically acceptable solvate thereof, and a fluorocarbon propellant, optionally in combination with one or more other pharmacologically active agents or one or more excipients.

公开(公告)号：PL322781A1

公开(公告)日：1998-02-16

申请号：PL32278196

申请日：1996-04-11

Applicant: GLAXO WELLCOME INC

Inventor： ASHURST IAN C ,  HERMAN CRAIG S ,  LI-BOVET LI ,  RIEBE MICHAEL T

IPC: B65D83/38 ,  A61K9/00 ,  A61K9/12 ,  A61K9/72 ,  A61K31/137 ,  A61K31/57 ,  A61K31/573 ,  A61M15/00 ,  A61P11/00 ,  B05D5/08 ,  B65D83/14

Abstract: A metered dose inhaler having part or all of its internal surfaces coated with one or more fluorocarbon polymers, optionally in combination with one or more non-fluorocarbon polymers, for dispensing an inhalation drug formulation comprising beclomethasone dipropionate or a physiologically acceptable solvate thereof, and a fluorocarbon propellant, optionally in combination with one or more other pharmacologically active agents or one or more excipients.

公开(公告)号：NO974738A

公开(公告)日：1997-12-11

申请号：NO974738

申请日：1997-10-13

Applicant: GLAXO WELLCOME INC

Inventor： ASHURST IAN C ,  HERMAN CRAIG S ,  LI-BOVET LI ,  RIEBE MICHAEL T

IPC: B65D83/38 ,  A61K9/00 ,  A61K9/12 ,  A61K9/72 ,  A61K31/137 ,  A61K31/57 ,  A61K31/573 ,  A61M15/00 ,  A61P11/00 ,  B05D5/08 ,  B65D83/14

CPC classification number: A61K9/008 ,  A61K31/573 ,  A61M15/009 ,  A61M2205/0222 ,  B65D83/54 ,  B65D83/752

公开(公告)号：NO974737L

公开(公告)日：1997-12-11

申请号：NO974737

申请日：1997-10-13

Applicant: GLAXO WELLCOME INC

Inventor： ASHURST IAN C ,  HERMAN CRAIG S ,  LI-BOVET LI ,  RIEBE MICHAEL T

IPC: A61K9/00 ,  A61K9/12 ,  A61K9/72 ,  A61K31/135 ,  A61K31/137 ,  A61K31/57 ,  A61K31/573 ,  A61M15/00 ,  A61P11/08 ,  B05D5/08 ,  B05D7/22 ,  B05D7/24 ,  B65D83/14

Abstract: Metered dose inhaler having all or part of its internal surfaces coated with one or more fluorocarbon polymers, opt. in combination with one or more non-fluorocarbon polymers, is used for dispensing an inhalation drug formulation comprising albuterol (also known as salbutamol) or one of its salts, and a fluorocarbon propellant, opt. in combination with one or more other pharmacologically active agents or one or more excipients. Also claimed is a metered dose inhaler system comprising a metered dose inhaler fitted into a suitable channelling device for oral or nasal inhalation of the drug formulation.

公开(公告)号：NO974736L

公开(公告)日：1997-12-11

申请号：NO974736

申请日：1997-10-13

Applicant: GLAXO WELLCOME INC

Inventor： ASHURST IAN C ,  HERMAN CRAIG S ,  LI-BOVET LI ,  RIEBE MICHAEL T

IPC: A61M15/00 ,  B05D5/08 ,  B65D83/00 ,  B65D83/14

Abstract: A metered dose inhaler characterised in that part or all of its internal surfaces are coated with a polymer blend of one or more fluorocarbon polymers in combination with one or more non-fluorocarbon polymers, for dispensing an inhalation drug formulation comprising salmeterol, or a physiologically acceptable salt thereof, and a fluorocarbon propellant, optionally in combination with one or more other pharmacologically active agents or one or more excipients, wherein a) the fluorocarbon polymer is selected from the group consisting of PTFE, PFA, FEP and mixtures thereof, b) the non-fluorocarbon polymer is selected from the group consisting of polyamideimides, polyimides, polyethersulfones, polyphenylene sulfides and amine-formaldehyde thermosetting resins, (c) the inhaler comprises a can made of metal whose interior surfaces are coated with the polymer blend.

公开(公告)号：NO974736A

公开(公告)日：1997-12-11

申请号：NO974736

申请日：1997-10-13

Applicant: GLAXO WELLCOME INC

Inventor： ASHURST IAN C ,  HERMAN CRAIG S ,  LI-BOVET LI ,  RIEBE MICHAEL T

IPC: A61M15/00 ,  B05D5/08 ,  B65D83/00 ,  B65D83/14

CPC classification number: B65D83/54 ,  A61M15/009 ,  A61M2205/0222 ,  A61M2205/0233

公开(公告)号：NO971422A

公开(公告)日：1997-05-23

申请号：NO971422

申请日：1997-03-25

Applicant: GLAXO WELLCOME INC

Inventor： LI-BOVET LI ,  JOHNSON KEITH ARTHUR

IPC: A61K9/12 ,  A61K9/00 ,  A61K9/72 ,  A61K47/06 ,  B01F17/20 ,  C07F9/09 ,  C07F9/10

CPC classification number: A61K9/008 ,  C07F9/10 ,  Y10S514/975