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公开(公告)号：KR1020130045452A
公开(公告)日：2013-05-06
申请号：KR1020110109656
申请日：2011-10-26
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A makeup cosmetic composition containing a cholesteric liquid crystal containing a useful pigment is provided to implement an optical property such as hologram when applied on skin or lip. CONSTITUTION: A makeup cosmetic composition contains 50.0-99.999 wt% of a cholesteric liquid crystal containing a useful pigment. The composition contains 0.001-10.0 wt% of the useful pigment. The cholesteric liquid crystal is a liquid crystal mixture containing a nematic liquid crystal(NLC) with chiral dopant which induces a periodic helical structure. The cholesteric liquid crystal selectively reflects light according to the pitch of a repetitive structure and the twisting direction of the helix. [Reference numerals] (AA) Optical characteristic from external appearances; (BB) Optical characteristic after being applied on lips; (CC) Comparative example 1; (DD) Comparative example 2; (EE) Comparative example 3; (FF) Example 1; (GG) Example 2
Abstract translation: 目的：提供一种含有含有有用颜料的胆甾型液晶的化妆品组合物，以在施用于皮肤或唇部时实现全息图等光学性质。 构成：化妆组合物含有50.0-99.999重量％的含有有用颜料的胆固醇液晶。 该组合物含有0.001-10.0重量％的有用颜料。 胆甾型液晶是含有引发周期性螺旋结构的手性掺杂剂的向列型液晶（NLC）的液晶混合物。 胆甾型液晶根据重复结构的螺距和螺旋的扭转方向选择性地反射光。 （附图标记）（AA）外观的光学特性; （BB）应用于唇部后的光学特性; （CC）比较例1; （DD）比较例2; （EE）比较例3 （FF）实施例1; （GG）实施例2
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公开(公告)号：KR1020130037405A
公开(公告)日：2013-04-16
申请号：KR1020110101797
申请日：2011-10-06
Applicant: (주)아모레퍼시픽
IPC: C07C233/43 , A61K8/42 , A61K31/165 , A61Q7/00
CPC classification number: C07C233/65 , C07C233/59 , C07C255/57
Abstract: PURPOSE: A novel adamantane derivative compound is provided to decrease androgen, thereby obtaining hair growth and sebum secretion inhibiting effects. CONSTITUTION: A novel adamantane derivative compound is represented by chemical formula 1. In chemical formula 1, X is -NHCO- or -CONH-; R1 is C0-C5 alkyl or C1-C5 alkoxy; R2 is selected from NO2, CN, and NH2; and R3 is C1-C5 haloalkyl. The anti-androgen composition comprises the compound, isomer thereof, pharmaceutically acceptable salt thereof, prodrug thereof, anhydride thereof, or a solvent thereof.
Abstract translation: 目的：提供一种新的金刚烷衍生物，以减少雄激素，从而获得毛发生长和皮脂分泌抑制作用。 组成：一种新颖的金刚烷衍生化合物由化学式1表示。在化学式1中，X是-NHCO-或-CONH-; R1是C0-C5烷基或C1-C5烷氧基; R2选自NO2，CN和NH2; 并且R 3是C 1 -C 5卤代烷基。 抗雄激素组合物包含化合物，其异构体，其药学上可接受的盐，其前药，其酸酐或其溶剂。
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公开(公告)号：KR101219281B1
公开(公告)日：2013-01-08
申请号：KR1020050103412
申请日：2005-10-31
Applicant: (주)아모레퍼시픽
IPC: C07C235/46
Abstract: 상기화학식 I에서 R은방향족기, 직쇄또는분지쇄의 C-C의알킬기또는알콕시기가치환된방향족기, C-C의시클로알킬기, C-C의시클로알케닐기, 아르알킬기, C-C의시클로알킬기또는 C-C의시클로알케닐기가치환된 C-C의알킬기, 융합고리이다.
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公开(公告)号：KR1020110007540A
公开(公告)日：2011-01-24
申请号：KR1020090065107
申请日：2009-07-16
Applicant: (주)아모레퍼시픽
IPC: A61K8/49 , A61Q19/08 , A61K31/352 , A61P17/18
CPC classification number: A61K8/498 , A61K8/418 , A61K8/466 , A61K2800/522 , A61Q19/08
Abstract: PURPOSE: A composition for skin anti-aging is provided to suppress matrix metalloprotease activation without skin irritation. CONSTITUTION: A composition for skin anti-aging contains 0.01-20 weight% of compound of chemical formula 1, isomer or pharmaceutically acceptable salt thereof as an active ingredient. The composition is used for preventing or treating wrinkling and skin aging. The composition is a pharmaceutical composition or cosmetic composition. The pharmaceutical composition is manufactured in the form of lotion, ointment, gel, cream, patch or spray. The cosmetic composition is used in the form of essence, nutrition cream, massage cream, pack, gel, essence, eye cream, cleansing cream, cleansing foam, pack, and powder.
Abstract translation: 目的：提供皮肤抗衰老的组合物，以抑制基质金属蛋白酶活化而无皮肤刺激。 构成：用于皮肤抗衰老的组合物含有0.01-20重量％的化学式1的化合物，其异构体或其药学上可接受的盐作为活性成分。 该组合物用于预防或治疗皱纹和皮肤老化。 该组合物是药物组合物或化妆品组合物。 药物组合物以洗剂，软膏，凝胶，霜剂，贴剂或喷雾剂的形式制备。 化妆品组合物以精华，营养霜，按摩霜，包装，凝胶，精华，眼霜，清洁霜，清洁泡沫，包装和粉末的形式使用。
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公开(公告)号：KR1020090020355A
公开(公告)日：2009-02-26
申请号：KR1020070085068
申请日：2007-08-23
Applicant: (주)아모레퍼시픽
Abstract: A sesamol derivative having skin whitening effect is provided to inhibit the activity of tyrosinase playing an important role of melanogenesis. A cosmetic composition comprising the sesamol derivative having skin whitening effect is also provided to improve the skin whitening effect. The sesamol derivative having skin whitening effect is represented by the chemical formula(1), wherein n is 2 or 3. The skin-whitening cosmetic composition comprises 0.01-20.00 wt.% of the sesamol derivative having skin whitening effect.
Abstract translation: 提供具有皮肤美白效果的芝麻酚衍生物，以抑制酪氨酸酶在黑素生成中起重要作用的活性。 还提供包含具有皮肤美白效果的芝麻酚衍生物的化妆品组合物以改善皮肤美白效果。 具有皮肤美白效果的芝麻酚衍生物由化学式（1）表示，其中n为2或3.皮肤美白化妆品组合物包含0.01-20.00重量％的具有皮肤美白效果的芝麻酚衍生物。
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Patent Agency Ranking
公开(公告)号：KR1020080087273A
公开(公告)日：2008-10-01
申请号：KR1020070029255
申请日：2007-03-26
Applicant: (주)아모레퍼시픽
IPC: C07C233/07 , C07C233/10
Abstract: A 3,5-dihydroxybenzoic acid derivative compound having anti-obesity activity is provided to obtain a pharmaceutical agent for preventing and treating diseases caused by abnormal fat metabolism, including obesity, hyperlipidemia, diabetes by inducing activation of IDH3-alpha and CPT1 promoters. A 3,5-dihydroxybenzoic acid derivative compound having anti-obesity activity is represented by the following formula 1, wherein R is adamantyl, cyclohexyl or hexyl. The 3,5-dihydroxybenzoic acid derivative compound includes N-adamantyl-3,5-dihydroxybenzamide, N-cyclohexyl-3,5-dihydroxybenzamide or N-hexyl-3,5-dihydroxybenzamide.
Abstract translation: 提供具有抗肥胖活性的3,5-二羟基苯甲酸衍生物化合物，以获得通过诱导IDH3-α和CPT1启动子的激活来预防和治疗由异常脂肪代谢引起的疾病，包括肥胖症，高脂血症，糖尿病的药剂。 具有抗肥胖活性的3,5-二羟基苯甲酸衍生化合物由下式1表示，其中R是金刚烷基，环己基或己基。 3,5-二羟基苯甲酸衍生物包括N-金刚烷基-3,5-二羟基苯甲酰胺，N-环己基-3,5-二羟基苯甲酰胺或N-己基-3,5-二羟基苯甲酰胺。
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公开(公告)号：KR1020060113110A
公开(公告)日：2006-11-02
申请号：KR1020050035986
申请日：2005-04-29
Applicant: (주)아모레퍼시픽
IPC: C07C239/18
CPC classification number: C07C259/06 , A61K8/42 , A61Q19/08 , C07C259/10
Abstract: Provided are a hydroxamic acid derivative which shows an antioxidizing effect and a collagen biosynthesis enhancing effect, its preparation method, and a skin preparation composition for external use containing the derivative. The hydroxamic acid derivative is represented by the formula 1, wherein R1 and R2 is a C1-C10 alkyl group; R3 is -(CH)n-; n is 0 or 1; and R4 is H or a methyl group. The method comprises the steps of reacting a 3,4-dialkoxybenzoic acid and methyl 4-aminobenzoate or methyl 4-aminophenyl acetate to prepare a benzamide compound; hydrolyzing a methyl ester group of the benzamide compound to prepare an acid; and reacting the acid with hydroxylamineÀHCl salt or N-methyl hydroxylamineÀHCl salt to prepare the hydroxamic acid derivative of the formula 1.
Abstract translation: 提供显示抗氧化作用和胶原生物合成增强效果的异羟肟酸衍生物，其制备方法和含有该衍生物的外用皮肤制剂组合物。 异羟肟酸衍生物由式1表示，其中R 1和R 2是C 1 -C 10烷基; R3是 - （CH）n-; n为0或1; R4为H或甲基。 该方法包括使3,4-二烷氧基苯甲酸与4-氨基苯甲酸甲酯或4-氨基苯基乙酸甲酯反应制备苯甲酰胺化合物的步骤; 水解苯甲酰胺化合物的甲基酯以制备酸; 并使酸与羟胺-HCl盐或N-甲基羟胺-HCl盐反应以制备式1的异羟肟酸衍生物。
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公开(公告)号：KR1020170003387A
公开(公告)日：2017-01-09
申请号：KR1020160067409
申请日：2016-05-31
Applicant: (주)아모레퍼시픽
IPC: C07C231/02 , C07C231/08 , C07C233/64 , C07C233/75 , A61K8/44 , A61Q19/02
CPC classification number: C07C231/02 , C07C213/02 , C07C249/08 , C07C2603/74 , C07C235/60 , C07C217/58 , C07C251/48
Abstract: 본발명은반응물질로사용하는벤질아민화합물의새로운제조방법을제시하고, 이를이용하여각 단계의반응조건을한정함으로써고수율로벤조산아미드화합물의제조방법에관한것으로, 이러한방법은대량생산이가능하여경제적인측면에서유리하다.
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公开(公告)号：KR101688815B1
公开(公告)日：2016-12-23
申请号：KR1020100078280
申请日：2010-08-13
Applicant: (주)아모레퍼시픽
Inventor： 백흥수
Abstract: 본발명은백모방지용및 백반증치료용조성물에관한것으로서, 보다상세하게는프로판노이드유도체를함유함으로써멜라노사이트의 MITF 발현을증가시켜멜라노사이트를활성화시키고멜라닌합성을촉진함으로써백모의유발을사전에예방하고흑모유발을촉진하며, 또한백반증치료에효과적인조성물에관한것이다.
Abstract translation: 目的：提供用于预防和治疗灰白色头发和白癜风的组合物，以增强黑素细胞中的MITF表达并促进黑素生成。 构成：用于预防或治疗灰白色和白癜风的组合物含有以化学式1的异戊烯基作为有效成分取代的0.001-50重量％的类异构体衍生物。 被异戊烯基取代的脯氨酸衍生物从布鲁氏菌（Broussonetia Kazinoki）中分离出来。
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