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公开(公告)号：KR101039753B1
公开(公告)日：2011-06-09
申请号：KR1020080072254
申请日：2008-07-24
Abstract: 본 발명은 금속 나노입자를 이용한 옥시도리덕타제 보조인자의 전기화학적 재생방법에 관한 것으로, 3-전극 시스템을 구비한 반응기 내에서 산화형의 옥시도리덕타제 보조인자를 메틸비올로겐, 루테늄 II 복합체 및 로듐 III 복합체로 구성되는 군으로부터 선택되는 어느 1종 이상의 1차 산화환원 매개체; 및 2차 산화환원 매개체인 금속 나노입자 존재 하에 전기화학적으로 환원형의 옥시도리덕타제 보조인자로 변환시켜 재생하는 방법에 관한 것이다. 본 발명의 금속 나노입자는 상기 재생방법에 있어서, 2차 산화환원 매개체이자 촉매로 작용하여 옥시도리덕타제 보조인자의 재생 속도를 상승시키는 효과를 나타내는 바, 옥시도리덕타제 효소를 이용하는 다양한 생촉매반응의 효율을 높이는데 매우 유용하게 사용될 수 있다.
옥시도리덕타제, 보조인자, 조효소, 금속나노입자, (헥사메틸벤젠-2,2′-비피리딘클로로)루테늄(II), 펜타메틸사이클로펜타디에닐-2,2'-비피리딘클로로)로듐(III), 전기화학적 방법, 생촉매반응-
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公开(公告)号：KR101859220B1
公开(公告)日：2018-05-21
申请号：KR1020160107192
申请日：2016-08-23
Applicant: 한국과학기술원
Abstract: 본발명은아밀로이드베타단백질의응집억제방법에관한것으로, 보다상세하게는철이도핑된카본나이트라이드나노시트를이용하여광 조사에의해베타아밀로이드단백질의응집을억제하는방법에관한것이다. 본발명에따른철이도핑된그래파이트카본나이트라이드를이용한아밀로이드베타단백질의응집억제방법은광 조사를통해비침습적으로응집을억제할수 있으며, 아밀로이드베타단백질의응집에의해유발되는치매, 알츠하이머병, 파킨슨병, 뇌졸중, 헌팅턴병등 다양한퇴행성신경질환의광역동치료에효과적으로이용될수 있다.
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公开(公告)号：KR101570698B1
公开(公告)日：2015-11-23
申请号：KR1020130148274
申请日：2013-12-02
Applicant: 한국과학기술원
Abstract: 본발명은에오신와이(Eosin Y)를이용한시토크롬 P450의활성방법에관한것이다. 본발명에따른시토크롬 P450의활성방법은세포질내 에오신와이(Eosin Y)의감광작용으로인하여, 시토크롬 P450의헴도메인(Heme domain)에직접전자를전달함으로써, 반응의간편성및 시토크롬 P450효소의산업적이용의경제성을도모할수 있는시토크롬 P450의활성방법을제공할수 있다.
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公开(公告)号：KR101570504B1
公开(公告)日：2015-11-19
申请号：KR1020140030338
申请日：2014-03-14
Applicant: 한국과학기술원
Abstract: 본발명은그래핀산화물과염료가흡착되어있는염료자가흡착형광촉매나노입자필름및 그제조방법에관한것으로, 보다상세하게는광촉매나노입자표면을그래핀옥사이드로랩핑(wrapping)한다음, 그래핀옥사이드로랩핑된광촉매나노입자를수열반응시키고염료를흡착시켜제조되는염료자가흡착형광촉매나노입자필름및 그제조방법에관한것이다. 본발명에따른염료자가흡착형광촉매나노입자의제조방법은그래핀을광촉매나노입자에랩핑하여염료가잘 흡착되고염료의침출(leaching)을대폭감소시키는간편한방법으로용이하게제조할수 있고, 상기제조된염료자가흡착형광촉매나노입자필름은산소검출기의주요구성요소로서효율적으로사용될수 있으며, 이를이용한산소의검출은환경, 의료및 식품응용등의다양한분야에유용하게이용될수 있다.
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Patent Agency Ranking66.发明公开
公开(公告)号：KR1020140020533A
公开(公告)日：2014-02-19
申请号：KR1020120087180
申请日：2012-08-09
Applicant: 한국과학기술원
CPC classification number: C12N9/0006 , B82Y5/00 , C01G55/00 , C07D487/22 , C07K5/06078 , C07K19/00 , C12N9/0014 , C12Y101/01001 , C12Y101/01027 , C12Y104/01002
Abstract: The present invention relates to a self-assembled dipeptide/porphyrin nanotube and a photocatalytic production method for oxidoreductase cofactors using the same. The photocatalytic production method for oxidoreductase cofactors according to the present invention converts light energy in visible radiation zone into electric energy using the self-assembled dipeptide/porphyrin nanotube in order to efficiently recycle cofactors, connects oxidoreductase reaction to cofactor recycling in order to finally produce fine chemicals and the likes from light energy so that the photocatalytic production method for oxidoreductase cofactors can be used for performing various biocatalysis using the oxidoreductase.
Abstract translation: 本发明涉及自组装二肽/卟啉纳米管和使用其的氧化还原酶辅因子的光催化制备方法。 根据本发明的氧化还原酶辅因子的光催化生产方法使用自组装的二肽/卟啉纳米管将可见光辐射区中的光能转化成电能，以有效地循环辅因子，将氧化还原酶反应连接于辅因子回收，以最终产生细 化学物质等，从而可以使用氧化还原酶辅因子的光催化剂生产方法进行使用氧化还原酶的各种生物催化。
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公开(公告)号：KR1020130113770A
公开(公告)日：2013-10-16
申请号：KR1020120036235
申请日：2012-04-06
Applicant: 한국과학기술원
CPC classification number: B01J37/0215 , B01J21/18 , B01J35/004 , B01J37/08
Abstract: PURPOSE: Hybrid photocatalyst nanoparticles and a manufacturing method thereof are provided to easily produce hybrid photocatalyst nanoparticles mixed with graphene by using a simple method without an activated catalyst or a carbonizing process and to improve photoactivity. CONSTITUTION: A method for manufacturing hybrid photocatalyst nanoparticles comprises the steps of: wrapping the surface of photocatalyst nanoparticles with graphene oxide; and producing hybrid photocatalyst nanoparticles by hydrothermally reacting the photocatalyst nanoparticles wrapped with the graphene oxide.
Abstract translation: 目的：提供混合光催化剂纳米颗粒及其制备方法，通过使用无活性催化剂或碳化方法的简单方法，轻松制备与石墨烯混合的杂化光催化剂纳米粒子，提高光活性。 构成：制备混合光催化剂纳米颗粒的方法包括以下步骤：用氧化石墨烯包裹光催化剂纳米颗粒的表面; 并通过用氧化石墨烯包裹的光催化剂纳米颗粒水热反应制备杂化光催化剂纳米颗粒。
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公开(公告)号：KR101222019B1
公开(公告)日：2013-01-14
申请号：KR1020110086083
申请日：2011-08-26
Applicant: 한국과학기술원
CPC classification number: C01B32/23 , A61L27/08 , A61L27/12 , C01F11/186
Abstract: PURPOSE: A graphene biomineral hybrid film and a manufacturing method of the same are provided to increase the viability of osteoblast by cultivating the osteoblast using the graphene biomineral hybrid film. CONSTITUTION: A manufacturing method of a graphene biomineral hybrid film includes the following steps: carbon dioxide is mixed with a solution containing a graphene oxide and calcium chloride; the mixture is filtered and dried to form a spherical graphene oxide-calcium carbonate(GO_CaCO_3) baterite; the spherical graphene oxide-calcium carbonate baterite is reduced to manufacture a graphene oxide-calcium carbonate(GOCaCO_3) hybrid film; and the thickness of the graphene oxide-calcium carbonate hybrid film is in a range between 50 and 300um.
Abstract translation: 目的：提供石墨烯生物矿物杂合膜及其制造方法，以通过使用石墨烯生物矿物混合膜培养成骨细胞来增加成骨细胞的活力。 构成：石墨烯生物矿物混合膜的制造方法包括以下步骤：将二氧化碳与含有氧化石墨烯和氯化钙的溶液混合; 将混合物过滤并干燥以形成球形石墨烯氧化物 - 碳酸钙（GO_CaCO_3）贝类; 氧化球形氧化碳 - 碳酸钙颗粒被还原成制造石墨烯氧化物 - 碳酸钙（GOCaCO_3）混合膜; 并且氧化石墨烯 - 碳酸钙混合膜的厚度在50和300um之间的范围内。
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公开(公告)号：KR1020120114996A
公开(公告)日：2012-10-17
申请号：KR1020110032882
申请日：2011-04-08
Applicant: 한국과학기술원
Abstract: PURPOSE: A micro fluid device for artificial photosynthesis and a manufacturing method thereof are provided to efficiently regenerate co-factor by converting the light energy of the visible light region into electrical energy by using nano-sized photo-sensitizer. CONSTITUTION: A manufacturing method of a micro fluid device for artificial photosynthesis comprises the following steps: laminating a valve layer which includes a valve channel on a solid substrate; laminating a fluid layer including a fluidic channel which is separated into a dark reaction section and a light reaction section; forming an air injection hole for injecting air into the valve channel; and respectively fixing a photo active compound and an oxidoreductase on the fluidic channel surfaces of the light and dark reaction sections. The bondage of the substrate, valve layer and fluid layer is completed by physical compression or chemical bondage. The photo active compound is quantum dot. The quantum dot is CdS, CdSe, CdTe, PbS, ZnS, InP, CIG or CIGS. The cofactor of the oxidoreductase is NADH, NADPH, FADH2 or FMNH2.
Abstract translation: 目的：提供用于人造光合作用的微流体装置及其制造方法，通过使用纳米尺寸的光敏剂将可见光区域的光能转换为电能来有效地再生辅助因子。 构成：用于人造光合作用的微流体装置的制造方法包括以下步骤：将包括阀通道的阀层层压在固体基板上; 层压包含分离成黑色反应部分和光反应部分的流体通道的流体层; 形成用于将空气注入到所述阀通道中的空气注入孔; 并分别将光活性化合物和氧化还原酶固定在光和暗反应部分的流体通道表面上。 衬底，阀层和流体层的粘合是通过物理压缩或化学粘合完成的。 光活性化合物是量子点。 量子点是CdS，CdSe，CdTe，PbS，ZnS，InP，CIG或CIGS。 氧化还原酶的辅因子是NADH，NADPH，FADH2或FMNH2。
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公开(公告)号：KR101093202B1
公开(公告)日：2011-12-12
申请号：KR1020090070903
申请日：2009-07-31
Applicant: 한국과학기술원
Abstract: 본발명은발광펩타이드나노구조체및 그제법에관한것으로, 보다상세하게는, 펩타이드를자기조립시켜나노구조체로형성함으로써란탄계이온분산의주형으로서작용하게함과더불어란탄계이온의발광력을향상시키는감광제로서의역할을수행하게한 발광펩타이드나노구조체및 각전구체용액의단순혼합을통해발광체들이균일하게분산된나노구조체의손쉬운합성이가능하게한 제법에관한것이다. 본발명에따른발광펩타이드나노구조체는발광력이우수할뿐만아니라, 가시광선영역내에서다양한발광색을가지므로, 바이오이미징및 바이오센서등의다양한분야에적용될수 있어매우유용하다.
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