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公开(公告)号:AU3968093A
公开(公告)日:1993-11-08
申请号:AU3968093
申请日:1993-03-24
Applicant: ABBOTT LAB
Inventor: CLARK FREDERIC L , CLIFT GILBERT , HENDRICK KENDALL B , LAGOCKI PETER A , MARTIN RICHARD R , MITCHELL JAMES E , MOORE LARRY W , PENNINGTON CHARLES D , WALKER EDNA S , SMITH JANE B , TAYI APPARAO , VAUGHT JAMES A , YOST DAVID A , KANEWSKE WILLIAM J III
IPC: G01N21/64 , B01L3/00 , B01L3/08 , B01L9/06 , B29C45/00 , G01N1/00 , G01N21/03 , G01N21/25 , G01N21/27 , G01N21/49 , G01N21/59 , G01N33/53 , G01N33/537 , G01N33/538 , G01N33/542 , G01N33/543 , G01N35/00 , G01N35/02 , G01N35/04 , G01N35/10 , H01J49/04 , G01N35/06
Abstract: An automated, continuous and random access analytical system, having apparatus and methodology capable of simultaneously performing multiple assays of liquid samples using different assay methodologies, and providing continuous and random access while performing a plurality of different assays on the same or different samples during the same time period, is disclosed. A method is also disclosed of operating an automated continuous and random access analytical system capable of simultaneously effecting multiple assays of a plurality of liquid samples wherein scheduling of various assays of the plurality of liquid samples is followed by creating a unit dose disposable and separately transferring a first liquid sample and reagents to a reaction vessel without initiation of an assay reaction sequence, followed by physical transfer of the unit dose disposable to a processing workstation, whereby a mixture of the unit dose disposable reagents and sample are achieved during incubation. The system is capable of performing more than one scheduled assay in any order, and assays where more than such scheduled assays are presented. The automated, continuous and random access analytical system is also capable of analyzing the incubated reaction mixtures independently and individually by at least two assay procedures.
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公开(公告)号:AU3967793A
公开(公告)日:1993-11-08
申请号:AU3967793
申请日:1993-03-24
Applicant: ABBOTT LAB
Inventor: RAYMOURE WILLIAM J , CLARK FREDERIC L , CLIFT GILBERT , HENDRICK KENDALL B , KANEWSKE WILLIAM J III , LAGOCKI PETER A , MARTIN RICHARD R , MITCHELL JAMES E , MOORE LARRY E , PENNINGTON CHARLES D , WALKER EDNA S , SMITH JANE B , TAYI APPARAO , VAUGHT JAMES A , YOST DAVID A
IPC: B01L3/00 , B01L3/08 , B01L9/06 , G01N1/00 , G01N21/25 , G01N33/53 , G01N33/537 , G01N33/538 , G01N33/542 , G01N33/543 , G01N35/00 , G01N35/02 , G01N35/04 , G01N35/10 , H01J49/04 , G01N33/546
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公开(公告)号:CA2512707A1
公开(公告)日:1993-10-14
申请号:CA2512707
申请日:1993-03-24
Applicant: ABBOTT LAB
Inventor: LAGOCKI PETER A , MARTIN RICHARD R , STANTON ALYN K , VICKSTROM RICHARD L , WATKINS WILLIAM E III , KANEWSKE WILLIAM J III , OLEKSAK CARL M , CLARK FREDERIC L , WINTER GARY E , SCHRIER PAUL R , HILLS DAVID B JR , VAUGHT JAMES A , CLIFT GILBERT , TAYI APPARAO , SMITH B JANE , YOST DAVID A , WOHLFORD ROBERT A , HENDRICK KENDALL B , PENNINGTON CHARLES D , RUMBAUGH WILLIAM , MOORE LARRY W , CLOONAN KEVIN M , MITCHELL JAMES E , WALKER EDNA S , HANCE ROBERT B
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公开(公告)号:CA2129368A1
公开(公告)日:1993-10-14
申请号:CA2129368
申请日:1993-03-24
Applicant: ABBOTT LAB
Inventor: SCHMIDT LINDA S , SPRONK ADRIAN M , CLARK FREDERIC L , CLIFT GILBERT , HENDRICK KENDALL B , SMITH B JANE , TAYI APPARAO , VAUGHT JAMES A , YOST DAVID A , KANEWSKE WILLIAM J III , LAGOCKI PETER A , MITCHELL JAMES E , MARTIN RICHARD R , MOORE LARRY W , PENNINGTON CHARLES D , WALKER EDNA S
IPC: B01L3/00 , B01L3/08 , B01L9/06 , G01N1/00 , G01N21/25 , G01N33/53 , G01N33/536 , G01N33/537 , G01N33/538 , G01N33/542 , G01N33/543 , G01N35/00 , G01N35/02 , G01N35/04 , G01N35/10 , H01J49/04
Abstract: 2129368 9320443 PCTABS00027 A method for verifying that an assay methodology is properly performed that assay reagents employed possess the necessary potency for accurately performing such assay methodology, and whether or not test samples or assay reagents have been tampered with or are adulterated, is described. The method is performed by employing an assay verification sample, comprising a positive analyte component and the test sample under analysis, wherein the assay verification sample is analyzed employing the same assay reagents and essentially the same assay methodology employed to analyze the test sample. The method is particularly useful for performing heterogeneous immunoassays on an automated continuous and random access analytical system.
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公开(公告)号:AT86669T
公开(公告)日:1993-03-15
申请号:AT87101130
申请日:1987-01-28
Applicant: ABBOTT LAB
Inventor: YOST DAVID A
IPC: C07H21/02 , C07H19/207 , C12Q1/00
Abstract: A reduced dinucleotide, preferably nicotinamide adenine dinucleotide (NADH), is stabilized in an aqueous base liquid containing propylene glycol, boric acid and a buffer capable of buffering within a pH range of 8-ll. The stabilized liquid contains greater than 50% (v/v) water. The remaining volume contains propylene glycol which has been chemically treated to remove oxidants. This reagent may be used by itself or in conjunction with an assay reagent system for use in the clinical laboratory.
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公开(公告)号:ES2004240A6
公开(公告)日:1988-12-16
申请号:ES8700470
申请日:1987-02-23
Applicant: ABBOTT LAB
Inventor: YOST DAVID A
IPC: C07H21/02 , C07H19/207 , C12Q1/00
Abstract: UN DINUCLEOTIDO REDUCIDO, PREFERIBLEMENTE EL DINUCLEOTIDO DE NICOTINAMIDA Y ADENINA (NADH), ES ESTABILIZADO EN UN LIQUIDO BASICO ACUOSO QUE CONTIENE PROPILENGLICOL, ACIDO BORICO Y UN TAMPON CAPAZ DE TAMPONAR DENTRO DE UN INTERVALO DE PH DE 8 A 11. EL LIQUIDO ESTABILIZADO CONTIENE MAS DEL 50% (V/V) DE AGUA. EL VOLUMEN RESTANTE CONTIENE PROPILENGLICOL QUE HA SIDO TRATADO QUIMICAMENTE PARA ELIMINAR LOS OXIDANTES. ESTE REACTIVO PUEDE SER UTILIZADO SOLO O JUNTO CON UN SISTEMA REACTIVO DE ENSAYO PARA USO EN EL LABORATORIO CLINICO.
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