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公开(公告)号:OA10627A
公开(公告)日:2001-04-24
申请号:OA70105
申请日:1997-10-10
Applicant: GLAXO WELLCOME INC
Inventor: ASHURST IAN C , HERMAN CRAIG S , LI-BOVET LI , RIEBE MICHAEL T
IPC: A61K9/00 , A61K9/12 , A61K9/72 , A61K31/135 , A61K31/137 , A61K31/57 , A61K31/573 , A61M15/00 , A61P11/08 , B05D5/08 , B05D7/22 , B05D7/24 , B65D83/14
Abstract: Metered dose inhaler having all or part of its internal surfaces coated with one or more fluorocarbon polymers, opt. in combination with one or more non-fluorocarbon polymers, is used for dispensing an inhalation drug formulation comprising albuterol (also known as salbutamol) or one of its salts, and a fluorocarbon propellant, opt. in combination with one or more other pharmacologically active agents or one or more excipients. Also claimed is a metered dose inhaler system comprising a metered dose inhaler fitted into a suitable channelling device for oral or nasal inhalation of the drug formulation.
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公开(公告)号:HU9802391A2
公开(公告)日:1999-02-01
申请号:HU9802391
申请日:1996-04-10
Applicant: GLAXO WELLCOME INC
Inventor: ASHURST IAN C , HERMAN CRAIG S , LI LI , RIEBE MICHAEL T
Abstract: A metered dose inhaler characterised in that part or all of its internal surfaces are coated with a polymer blend of one or more fluorocarbon polymers in combination with one or more non-fluorocarbon polymers, for dispensing an inhalation drug formulation comprising salmeterol, or a physiologically acceptable salt thereof, and a fluorocarbon propellant, optionally in combination with one or more other pharmacologically active agents or one or more excipients, wherein a) the fluorocarbon polymer is selected from the group consisting of PTFE, PFA, FEP and mixtures thereof, b) the non-fluorocarbon polymer is selected from the group consisting of polyamideimides, polyimides, polyethersulfones, polyphenylene sulfides and amine-formaldehyde thermosetting resins, (c) the inhaler comprises a can made of metal whose interior surfaces are coated with the polymer blend.
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公开(公告)号:BG102021A
公开(公告)日:1998-07-31
申请号:BG10202197
申请日:1997-11-05
Applicant: GLAXO WELLCOME INC
Inventor: ASHURST IAN C , HERMAN CRAIG S , LI-BOVET LI , RTEBE MICHAEL T
IPC: A61K9/00 , A61K9/12 , A61K9/72 , A61K31/135 , A61K31/137 , A61K31/57 , A61K31/573 , A61M15/00 , A61P11/08 , B05D5/08 , B05D7/22 , B05D7/24 , B65D83/14
Abstract: The inhaler has partially or completely covered innersurfaces with one or more fluorohydrocarbon polymers, optionallyin a combination with one or more non-fluorohydrocarbon polymers.It is used for dosing inhalation medicaments consisting ofalbuterol or its physiologically acceptable salt andflurorhydrocarbon propellent, optionally in combination with oneor more pharmacologically active substances in one or morefillers.22 claims
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公开(公告)号:TR199701169T1
公开(公告)日:1998-03-21
申请号:TR9701169
申请日:1996-04-10
Applicant: GLAXO WELLCOME INC
Inventor: ASHURST IAN C , HERMAN CRAIG S , LI-BOVET LI , RIEBE MICHAEL THOMAS
Abstract: A metered dose inhaler characterised in that part or all of its internal surfaces are coated with a polymer blend of one or more fluorocarbon polymers in combination with one or more non-fluorocarbon polymers, for dispensing an inhalation drug formulation comprising salmeterol, or a physiologically acceptable salt thereof, and a fluorocarbon propellant, optionally in combination with one or more other pharmacologically active agents or one or more excipients, wherein a) the fluorocarbon polymer is selected from the group consisting of PTFE, PFA, FEP and mixtures thereof, b) the non-fluorocarbon polymer is selected from the group consisting of polyamideimides, polyimides, polyethersulfones, polyphenylene sulfides and amine-formaldehyde thermosetting resins, (c) the inhaler comprises a can made of metal whose interior surfaces are coated with the polymer blend.
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公开(公告)号:CZ9703260A3
公开(公告)日:1998-02-18
申请号:CZ326097
申请日:1996-04-10
Applicant: GLAXO WELLCOME INC
Inventor: ASHURST IAN C , HERMAN CRAIG S , LI LI , RIEBE MICHAEL T
CPC classification number: B65D83/54 , A61M15/009 , A61M2205/0222 , A61M2205/0233
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公开(公告)号:CZ326097A3
公开(公告)日:1998-02-18
申请号:CZ326097
申请日:1996-04-10
Applicant: GLAXO WELLCOME INC
Inventor: ASHURST IAN C , HERMAN CRAIG S , LI LI , RIEBE MICHAEL T
Abstract: A metered dose inhaler characterised in that part or all of its internal surfaces are coated with a polymer blend of one or more fluorocarbon polymers in combination with one or more non-fluorocarbon polymers, for dispensing an inhalation drug formulation comprising salmeterol, or a physiologically acceptable salt thereof, and a fluorocarbon propellant, optionally in combination with one or more other pharmacologically active agents or one or more excipients, wherein a) the fluorocarbon polymer is selected from the group consisting of PTFE, PFA, FEP and mixtures thereof, b) the non-fluorocarbon polymer is selected from the group consisting of polyamideimides, polyimides, polyethersulfones, polyphenylene sulfides and amine-formaldehyde thermosetting resins, (c) the inhaler comprises a can made of metal whose interior surfaces are coated with the polymer blend.
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公开(公告)号:PL322771A1
公开(公告)日:1998-02-16
申请号:PL32277196
申请日:1996-04-10
Applicant: GLAXO WELLCOME INC
Inventor: ASHURST IAN C , HERMAN CRAIG S , LI-BOVET LI , RIEBE MICHAEL T
Abstract: A metered dose inhaler characterised in that part or all of its internal surfaces are coated with a polymer blend of one or more fluorocarbon polymers in combination with one or more non-fluorocarbon polymers, for dispensing an inhalation drug formulation comprising salmeterol, or a physiologically acceptable salt thereof, and a fluorocarbon propellant, optionally in combination with one or more other pharmacologically active agents or one or more excipients, wherein a) the fluorocarbon polymer is selected from the group consisting of PTFE, PFA, FEP and mixtures thereof, b) the non-fluorocarbon polymer is selected from the group consisting of polyamideimides, polyimides, polyethersulfones, polyphenylene sulfides and amine-formaldehyde thermosetting resins, (c) the inhaler comprises a can made of metal whose interior surfaces are coated with the polymer blend.
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公开(公告)号:PL322770A1
公开(公告)日:1998-02-16
申请号:PL32277096
申请日:1996-04-10
Applicant: GLAXO WELLCOME INC
Inventor: ASHURST IAN C , HERMAN CRAIG S , LI-BOVET LI , RIEBE MICHAEL T
IPC: A61K9/12 , A61K31/56 , A61K31/569 , A61M15/00 , A61M15/08 , A61M16/00 , A61P11/00 , B05D5/00 , B05D5/08 , B65D83/14
Abstract: A metered dose inhaler having part or all of its internal surfaces coated with one or more fluorocarbon polymers, optionally in combination with one or more non-fluorocarbon polymers, for dispensing an inhalation drug formulation comprising fluticasone propionate, or a physiologically acceptable solvate thereof, and a fluorocarbon propellant optionally in combination with one or more other pharmacologically active agents or one or more excipients.
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公开(公告)号:MX9707863A
公开(公告)日:1997-11-29
申请号:MX9707863
申请日:1996-04-10
Applicant: GLAXO WELLCOME INC
Inventor: ASHURST IAN C , HERMAN CRAIG S , LI-BOVET LI , RIEBE MICHAEL T
IPC: A61K9/00 , A61K9/12 , A61K9/72 , A61K31/135 , A61K31/137 , A61K31/57 , A61K31/573 , A61M15/00 , A61P11/08 , B05D5/08 , B05D7/22 , B05D7/24 , B65D83/14 , A61K09/72
Abstract: Un inhalador de dosis medida que tiene parte o el total de sus superficies interna revestidas con uno o más polímeros de fluorocarburo, opcionalmente en combinacion con uno o más polímeros sin fluorocarburo, para distribuir una formulacion del fármaco para inhalacion que comprende albuterol o una sal del mismo fisiologicamente aceptable, y un propulsor de fluorocarburo, opcionalmente en combinacion con uno o más de otros agentes farmacologicamente activos y uno o más excipientes.
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公开(公告)号:MX9707862A
公开(公告)日:1997-11-29
申请号:MX9707862
申请日:1996-04-10
Applicant: GLAXO WELLCOME INC
Inventor: ASHURST IAN C , HERMAN CRAIG S , LI-BOVET LI , RIEBE MICHAEL THOMAS
IPC: A61K9/12 , A61K31/56 , A61K31/569 , A61M15/00 , A61M15/08 , A61M16/00 , A61P11/00 , B05D5/00 , B05D5/08 , B65D83/14 , B05D05/08
Abstract: Un inhalador de dosis regulada que tiene parte o todas de estas superficies internas recubiertas con uno o más polímeros de fluorocarbono, opcionalmente en combinacion con uno o más polímeros sin fluorocarbono, para preparar una formulacion del fármaco para inhalacion que comprende de propionato de fluticasona, o un solvato aceptable fisiologicamente del mismo, en combinacion con uno o más de otros agentes activos farmacologicamente o uno o más excipientes.
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