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公开(公告)号:SE7612263A
公开(公告)日:1977-05-12
申请号:SE7612263
申请日:1976-11-03
Applicant: HOFFMANN LA ROCHE
Inventor: FURST A , MULLER M , KERB U , WIECHERT R
CPC classification number: C07J21/00 , C07J21/006 , C07J41/0038 , C07J63/00
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公开(公告)号:SE7602849A
公开(公告)日:1976-10-04
申请号:SE7602849
申请日:1976-02-27
Applicant: HOFFMANN LA ROCHE
Inventor: ALIG L , FURST A , MULLER M , KERB U , WIECHERT R , KIESLICH K , NICKOLSON R
IPC: A61K31/185 , A61K31/19 , A61K31/21 , A61K31/215 , A61K31/22 , A61K31/56 , A61P5/38 , A61P29/00 , C07J63/00 , C12P33/02
CPC classification number: C07J63/008 , C07J63/00 , Y10S514/87 , Y10S514/93
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公开(公告)号:SE7411947A
公开(公告)日:1975-03-27
申请号:SE7411947
申请日:1974-09-23
Applicant: HOFFMANN LA ROCHE
IPC: C07J63/00
CPC classification number: C07J63/008
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公开(公告)号:BE685305A
公开(公告)日:1967-02-10
申请号:BE685305D
申请日:1966-08-10
Applicant: HOFFMANN LA ROCHE
Inventor: FURST A , FURLENMEIER A , LANGEMANN A , WALDVOGEL G , HOCKS P , KERB U , WIECHERT R
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公开(公告)号:AU515487B2
公开(公告)日:1981-04-09
申请号:AU3512378
申请日:1978-04-14
Applicant: HOFFMANN LA ROCHE
Inventor: ALIG L , MULLER M , KERB U , WIECHERT R , FURST A
IPC: A61K31/12 , A61K31/215 , A61K31/22 , A61K31/57 , A61P29/00 , C07J63/00 , A61K31/23 , A61K31/235 , A61K31/19 , A61K31/445 , A61K31/40 , A61K31/66 , A61K31/095
Abstract: D-homopregnanes of the formula I wherein R6 is hydrogen, chloro, fluoro or methyl; X is beta -hydroxymethylene or carbonyl; R17a is hydroxy, lower alkanoyloxy or aroyloxy; R21 is hydrogen, chloro, fluoro, hydroxy, lower alkanoyloxy, aroyloxy, sulfate or phosphate; and the dotted line in the 1,2-position of the A-ring denotes an additional carbon-carbon bond AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AS THE ACTIVE INGREDIENT ARE DISCLOSED. The D-homopregnanes of the present invention exhibit hormonal activity and are useful for the treatment of inflammation.
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公开(公告)号:ZA8000294B
公开(公告)日:1980-12-31
申请号:ZA8000294
申请日:1980-01-17
Applicant: HOFFMANN LA ROCHE
Inventor: KERB U , FURST A , KIESLICH K , ALIG L , MULLER M , WEICHERT R
CPC classification number: C07J63/008 , C12P33/02 , C12P33/08
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公开(公告)号:BR8001059A
公开(公告)日:1980-11-04
申请号:BR8001059
申请日:1980-02-22
Applicant: HOFFMANN LA ROCHE
IPC: C07C43/196 , A61K31/045 , A61K31/10 , A61K31/12 , A61K31/19 , A61K31/265 , A61K31/275 , A61K31/34 , A61K31/585 , A61P5/38 , C07C27/00 , C07C29/147 , C07C35/37 , C07C41/00 , C07C43/18 , C07C45/00 , C07C49/727 , C07C51/00 , C07C59/42 , C07C59/62 , C07C59/90 , C07C67/00 , C07C253/00 , C07C255/46 , C07C313/00 , C07C323/17 , C07C323/22 , C07C323/61 , C07C325/00 , C07C327/28 , C07D307/94 , C07J20060101 , C07J19/00
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公开(公告)号:PH13603A
公开(公告)日:1980-08-05
申请号:PH19111
申请日:1976-11-09
Applicant: HOFFMANN LA ROCHE
Inventor: MULLER M , FURST A , WIECHERT R , KERB U
IPC: A61K31/075 , A61K31/125 , A61K31/56 , A61P5/00 , C07J21/00 , C07J41/00 , C07J63/00 , C07J61/00
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公开(公告)号:SE7804552L
公开(公告)日:1978-10-22
申请号:SE7804552
申请日:1978-04-20
Applicant: HOFFMANN LA ROCHE
Inventor: ALIG L , FURST A , MULLER M , KERB U , WIECHERT R
Abstract: D-homopregnanes of the formula I wherein R6 is hydrogen, chloro, fluoro or methyl; X is beta -hydroxymethylene or carbonyl; R17a is hydroxy, lower alkanoyloxy or aroyloxy; R21 is hydrogen, chloro, fluoro, hydroxy, lower alkanoyloxy, aroyloxy, sulfate or phosphate; and the dotted line in the 1,2-position of the A-ring denotes an additional carbon-carbon bond AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AS THE ACTIVE INGREDIENT ARE DISCLOSED. The D-homopregnanes of the present invention exhibit hormonal activity and are useful for the treatment of inflammation.
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公开(公告)号:SE7714467A
公开(公告)日:1978-06-21
申请号:SE7714467
申请日:1977-12-19
Applicant: HOFFMANN LA ROCHE
CPC classification number: C07J63/008 , Y10S514/869 , Y10S514/96 , Y10S514/962
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