公开(公告)号：HK1124938A1

公开(公告)日：2009-07-24

申请号：HK09102754

申请日：2009-03-23

Applicant: LUMINEX CORP

Inventor： CALVIN EDWARD A ,  ROTH WAYNE D

IPC: G01N20060101 ,  G06F19/00

Abstract: Methods, data structures, and systems for classifying particles are provided. In particular, the methods and systems are configured to acquire a first set of data corresponding to measurable parameters of a microparticle and identify a location of a look-up table to which the first set of data corresponds, wherein the look-up table is framed by values associated with at least one of the measurable parameters. Furthermore, the methods and systems are configured to determine whether the first set of data fits one or more predefined algorithms respectively indicative of a different microparticle classification associated with the identified location of the look-up table. The methods and systems are further configured to classifying the microparticle within at least one predefined categorization based upon the determination of whether the first set of data fits the one or more predefined algorithms.

公开(公告)号：CA2984772A1

公开(公告)日：2007-03-29

申请号：CA2984772

申请日：2006-09-21

Applicant: LUMINEX CORP

Inventor： ROTH WAYNE D

IPC: G01N15/00

Abstract: Methods, storage mediums, and systems for image data processing are provided. Embodiments for the methods, storage mediums, and systems include configurations to perform one or more of the following steps: background signal measurement, particle identification using classification dye emission and cluster rejection, inter-image alignment, inter-image particle correlation, fluorescence integration of reporter emission, and image plane normalization.

公开(公告)号：CA2617678A1

公开(公告)日：2007-02-08

申请号：CA2617678

申请日：2006-08-01

Applicant: LUMINEX CORP

Inventor： ROTH WAYNE D ,  CALVIN EDWARD A

IPC: G01N15/14 ,  G06F19/00

Abstract: Methods, data structures, and systems for classifying particles are provided. In particular, the methods and systems are configured to acquire a first set of data corresponding to measurable parameters of a microparticle and identify a location of a look-up table to which the first set of data corresponds, wherein the look-up table is framed by values associated with at least one of the measurable parameters. Furthermore, the methods and systems are configured to determine whether the first set of data fits one or more predefined algorithms respectively indicative of a different microparticle classification associated with the identified location of the look-up table. The methods and systems are further configured to classifying the microparticle within at least one predefined categorization based upon the determination of whether the first set of data fits the one or more predefined algorithms.

公开(公告)号：CA2535333A1

公开(公告)日：2005-02-24

申请号：CA2535333

申请日：2004-08-13

Applicant: LUMINEX CORP

Inventor： ROTH WAYNE D ,  MOORE DOUGLAS E

IPC: G01N15/14

Abstract: Various methods for controlling one or more parameters of a flow cytometer type measurement system are provided. One embodiment includes monitoring parameter(s) of the measurement system during measurements of sample microspheres. The method also includes altering the parameter(s) in real tim e based on the monitoring. Another method includes monitoring a temperature proximate to the measurement system. One such method includes altering a bia s voltage of an avalanche photo diode in response to the temperature using empirically derived data. A different such method includes altering output signals of a photomultiplier tube in response to the temperature using a characteristic curve. Some methods include monitoring a temperature of a fluid, in which sample microspheres are disposed, that will flow through the flow cytometer type measurement system. This method also includes determinin g a velocity of the sample microspheres in the measurement system from a viscosity of the fluid at the temperature.

公开(公告)号：CA2534859A1

公开(公告)日：2005-02-24

申请号：CA2534859

申请日：2004-08-03

Applicant: LUMINEX CORP

Inventor： ROTH WAYNE D

IPC: G01N15/14

Abstract: Various light emitting diode (LED) based measurement systems and methods are provided. One system includes one or more arrays of LEDs (14, 16, 18) arrang ed along a flow path (20) of a sample (10). The array(s) are configured to illuminate the sample as the sample moves along the flow path. The system al so includes one or more detectors (24) configured to detect light resulting fro m illumination of the sample by the array(s). One method includes illuminating a microsphere at different positions along a flow path of the microsphere. The method also includes detecting light resulting from the illumination to produce individual output signals corresponding to the illumination at the different positions. The method further includes combining the individual OUTPUT signals to produce a single output signal having a signal-to-noise ratio that is greater than a signal-to-noise ratio of the individual output signals.

公开(公告)号：AU2004265989A1

公开(公告)日：2005-02-24

申请号：AU2004265989

申请日：2004-08-13

Applicant: LUMINEX CORP

Inventor： MOORE DOUGLAS E ,  ROTH WAYNE D

IPC: G01N15/14

Abstract: A method for controlling one or more parameters of a flow cytometer type measurement system, is disclosed. The comprises the following steps - measuring a time in which a microsphere (10) travels from a first detection window of the flow cytometer type measurement system to a second detection window of the measurement system; and - altering an applied pressure of the measurement system such that the time is substantially constant.