公开(公告)号：IN162113B

公开(公告)日：1988-03-26

申请号：IN657CA1984

申请日：1984-09-18

Applicant: SURVIVAL TECHNOLOGY

Inventor： SARNOFF STANLEY JAY ,  CALKINS GEORGE B ,  TARELLO WILLIAM R

IPC: A61M20060101 ,  A61M5/19 ,  A61M5/20 ,  A61M3/00

公开(公告)号：ZA8603583B

公开(公告)日：1986-12-30

申请号：ZA8603583

申请日：1986-05-14

Applicant: SURVIVAL TECHNOLOGY

Inventor： SARNOFF STANLEY JAY

IPC: A61K31/66 ,  A61K38/44 ,  A61K

CPC classification number: A61K31/66 ,  A61K38/446

公开(公告)号：AU5950586A

公开(公告)日：1986-12-24

申请号：AU5950586

申请日：1986-05-19

Applicant: SURVIVAL TECHNOLOGY

Inventor： SARNOFF STANLEY JAY ,  LOPEZ CLAUDIO

IPC: A61M5/178 ,  A61M5/20 ,  A61M5/24

Abstract: An automatic injecting device including an elongated housing assembly, a stressed spring assembly mounted within the housing assembly so as to be released in response to a predetermined manual acutation procedure, and a medicament cartridge assembly mounted within the housing assembly in cooperating relation with the stressed spring assembly comprising a hypodermic needle and a medicament container housing forward and rearward individual dosages of different relatively incompatible liquid medicaments mounted therein and separated by a deformable stopper. The medicament container is formed of glass and includes a cylindrical wall open at its rearward end and having an exteriorly flanged necked down forward end portion. A hub assembly connects the exteriorly flanged necked down forward end portion with the hypodermic needle. A separate fitment of molded plastic material is mounted within the interior of the cylindrical glass wall adjacent the necked down forward end portion thereof for radially inwardly deforming the stopper during operation and thereby providing an axial by-pass in the periphery thereof.

公开(公告)号：DK528386D0

公开(公告)日：1986-11-05

申请号：DK528386

申请日：1986-11-05

Applicant: SURVIVAL TECHNOLOGY

Inventor： SARNOFF STANLEY JAY ,  SOBEL BURTON E

IPC: A61K20060101 ,  A61K31/415 ,  A61K38/38 ,  A61K38/49 ,  A61K47/18 ,  A61K

公开(公告)号：ZA861695B

公开(公告)日：1986-10-29

申请号：ZA861695

申请日：1986-03-06

Applicant: SURVIVAL TECHNOLOGY

Inventor： SARNOFF STANLEY JAY

IPC: A61K38/00 ,  A61K31/415 ,  A61K38/44 ,  A61K38/49 ,  A61K47/18 ,  A61K

公开(公告)号：ZA8601695B

公开(公告)日：1986-10-29

申请号：ZA8601695

申请日：1986-03-06

Applicant: SURVIVAL TECHNOLOGY

Inventor： SARNOFF STANLEY JAY

IPC: A61K38/00 ,  A61K31/415 ,  A61K38/44 ,  A61K38/49 ,  A61K47/18 ,  A61K

CPC classification number: A61K9/0019 ,  A61K31/415 ,  A61K38/446 ,  A61K38/49 ,  A61K47/18 ,  A61K33/02 ,  A61K31/13 ,  A61K2300/00

公开(公告)号：GR861288B

公开(公告)日：1986-09-16

申请号：GR860101288

申请日：1986-05-16

Applicant: SURVIVAL TECHNOLOGY

Inventor： SARNOFF STANLEY JAY

IPC: A61K31/66 ,  A61K38/44

Abstract: The absorption of a scavenger of oxygen free radicals generated at the time of reperfusion or the absorption of an agent preventing the cytotoxic effects on healthy cells in a mammal. e.g. superoxide dismutase or S-aminotrimethyleneaminoethyl thiophosphate is enhanced by substantially simultaneously administering an absorption enhancing agent therefore, e.g. hydroxylamine or a non-toxic salt thereof. It is also part of the invention to inject WR-2721 intravenously or intramuscularly as a scavenger of oxygen free radicals even in the absence of an absorption enhancing agent.

公开(公告)号：GR860804B

公开(公告)日：1986-07-21

申请号：GR860100804

申请日：1986-03-27

Applicant: SURVIVAL TECHNOLOGY

Inventor： SARNOFF STANLEY JAY ,  BURTON SOBEL E

IPC: A61K20060101 ,  A61K47/00 ,  C12N9/48

公开(公告)号：PT82277A

公开(公告)日：1986-04-01

申请号：PT8227786

申请日：1986-03-26

Applicant: SURVIVAL TECHNOLOGY

Inventor： SARNOFF STANLEY JAY ,  SOBEL BURTON E

IPC: A61K20060101 ,  A61K47/00 ,  C12N9/48 ,  C07K15/00

Abstract: The absorption of a therapeutically active protein (I) in the blood is improved by intramuscular injection of (I) together with an absorption enhancing agent (II). Particularly, the method is used where (I) has a short in vivo half-life and allows an effective concn. to be maintained for at least 30 min. Also new are packages contg. (I) and (II).

公开(公告)号：AU4674485A

公开(公告)日：1986-03-07

申请号：AU4674485

申请日：1985-08-08

Applicant: SURVIVAL TECHNOLOGY

Inventor： SARNOFF STANLEY JAY

IPC: A61K31/13 ,  A61K31/415 ,  A61K31/66 ,  A61K33/02 ,  A61K38/38 ,  A61K38/43 ,  A61K38/44 ,  A61K38/49 ,  A61K47/18 ,  A61M5/19 ,  A61M5/20 ,  A61N1/36

Abstract: The absorption rate of proteins with medicinal properties in the blood is enhanced by administering the protein intramuscularly together with an absorption enhancing agent, e.g. hydroxylamine or a salt thereof.