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    3D-printed miniature biological constructs
    72.
    发明授权
    3D-printed miniature biological constructs 有权

    公开(公告)号：US10934538B2

    公开(公告)日：2021-03-02

    申请号：US15404291

    申请日：2017-01-12

    Applicant: Cleveland State University

    Inventor： Moo-Yeal Lee

    IPC: C12N11/04 ,  G01N33/50 ,  C12N5/071 ,  C12Q1/02

    Abstract: A method of creating a miniature multicellular biological construct and a method for studying cellular environments using the miniature multicellular biological construct is provided. The method for making the miniature multicellular biological construct includes suspending cells in a hydrogel, depositing the cell-suspension into a microwell, gelling the cell-suspension, and incubating the cell-suspension. The method for studying cellular environments includes imaging the miniature multicellular biological construct.

    ACTIVE RADIAL MAGNETIC BEARING PHASED ARRAY
    76.
    发明申请
    ACTIVE RADIAL MAGNETIC BEARING PHASED ARRAY 审中-公开

    公开(公告)号：US20180128313A1

    公开(公告)日：2018-05-10

    申请号：US15344886

    申请日：2016-11-07

    Applicant: Cleveland State University

    Inventor： Jerzy T. Sawicki ,  Kenneth R. Bischof

    IPC: F16C32/04

    CPC classification number: F16C32/048 ,  F16C32/0444 ,  F16C32/0446 ,  F16C32/0453 ,  F16C2233/00

    Abstract: A rotor bearing system radially supporting a rotor, held in magnetic suspension without contact, by active radial magnetic bearing phased arrays, bearing sensors used to measure the rotor motion and bearing properties, a controller system used to adjust variable magnetic bearing parameters via amplifiers for each array element in response to bearing sensors, to change bearing local array element stiffness and damping, generating bearing forces for levitating the rotor, stabilizing rotor vibrations, and acting as a rotor vibration actuator.

    EXTENDED ACTIVE DISTURBANCE REJECTION CONTROLLER
    77.
    发明申请
    EXTENDED ACTIVE DISTURBANCE REJECTION CONTROLLER 审中-公开
    扩展的主动干扰抑制控制器

    公开(公告)号：US20160154388A1

    公开(公告)日：2016-06-02

    申请号：US15007281

    申请日：2016-01-27

    Applicant: Cleveland State University

    Inventor： Zhiqiang Gao ,  Gang Tian

    IPC: G05B13/04 ,  G06F17/10

    CPC classification number: G05B13/048 ,  G05B5/01 ,  G05B11/42 ,  G05B13/02 ,  G06F17/10

    Abstract: Multiple designs, systems, methods and processes for controlling a system or plant using an extended active disturbance rejection control (ADRC) based controller are presented. The extended ADRC controller accepts sensor information from the plant. The sensor information is used in conjunction with an extended state observer in combination with a predictor that estimates and predicts the current state of the plant and a co-joined estimate of the system disturbances and system dynamics. The extended state observer estimates and predictions are used in conjunction with a control law that generates an input to the system based in part on the extended state observer estimates and predictions as well as a desired trajectory for the plant to follow.

    Abstract translation: 提出了使用基于扩展主动干扰抑制控制（ADRC）的控制器来控制系统或设备的多种设计，系统，方法和过程。 扩展的ADRC控制器接收来自工厂的传感器信息。 传感器信息与扩展状态观察器结合使用，预测器与估计和预测设备的当前状态以及系统干扰和系统动态的共同估计结合使用。 扩展状态观察者估计和预测结合使用一部分基于扩展状态观察者估计和预测以及工厂遵循的期望轨迹而产生系统输入的控制规则。

    CORONAVIRUS TREATMENT COMPOSITION AND METHOD
    79.
    发明公开
    CORONAVIRUS TREATMENT COMPOSITION AND METHOD 审中-公开

    公开(公告)号：US20230310474A1

    公开(公告)日：2023-10-05

    申请号：US18109021

    申请日：2023-02-13

    Applicant: Cleveland State University ,  University of Tennessee Research Foundation

    Inventor： Xue-Long Sun ,  Guoyun Chen

    IPC: A61K31/7028 ,  A61P31/14

    CPC classification number: A61K31/7028 ,  A61P31/14

    Abstract: An antiviral composition contains a sialidase inhibitor. Methods for treating a viral infection include administering the composition to a patient. The sialidase inhibitor may be of general formula (l)





    wherein R1 is selected from the group consisting of OH, O-acetyl, N3, OCOCH2X1 and NHCOCHX1; X1 is selected from the group consisting of H, a C1-C5 alkyl group, acetyl, propionyl, butyryl, valoryl, hexanoyl, pentanoyl, and 2-methylpropanyl; R2 is H or COCH2X2; X2 is selected from the group consisting of H, a C1-C5 alkyl group, acetyl, propionyl, butyryl, valoryl, hexanoyl, pentanoyl, and 2-methylpropanyl; R3 is selected from the group consisting of H, OH, COCH2X3 and OCOCH2X3; X3 is selected from the group consisting of H, a C1-C5 alkyl group, acetyl, propionyl, butyryl, valoryl, hexanoyl, pentanoyl, and 2-methylpropanoal; R4 is selected from the group consisting of H, OH, a C1-C6 alkyl group, and CH2X4; and X4 is H or a C1-C6 alkyl group.

    Rotation monitoring system and method
    80.
    发明授权
    Rotation monitoring system and method 有权

    公开(公告)号：US11571146B2

    公开(公告)日：2023-02-07

    申请号：US16502423

    申请日：2019-07-03

    Applicant: Cleveland State University

    Inventor： Christopher A. Schroeck ,  Antonie J. van den Bogert

    IPC: A61B5/11 ,  A61B5/00

    Abstract: A rotation monitoring system may be attached to a limb and can identify ranges of motion that are associated with injuries or poor performance. In some embodiments, the device is designed to monitor flexion and orientation of joints and limbs, developed specifically around identifying stress concentrating behavior on the ACL. Tests performed show that the designed device can read flexion and orientation of the knee, is durable enough to be used in real-world conditions, and does not impede on the subject's movements.

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