公开(公告)号：WO2018022165A3

公开(公告)日：2018-02-01

申请号：PCT/US2017/030906

申请日：2017-05-03

Applicant: UNIVERSITY OF MARYLAND, COLLEGE PARK OFFICE OF TECHNOLOGY COMMERCIALIZATION

Inventor： BARAS, John S. ,  WENG, Xiangnan

IPC: G06Q30/00

Abstract: Various communication systems may benefit from optimized delivery or dissemination of information. For example, various wireless networks including heterogeneous wireless may benefit from joint optimization for social content delivery or dissemination over such networks. A method can include selecting content to deliver according to user reward values given wireless capacity constraints. The method can also include delivering the content to a plurality of users via a wireless network comprising different transmission modes.

公开(公告)号：WO2018022165A2

公开(公告)日：2018-02-01

申请号：PCT/US2017/030906

申请日：2017-05-03

Applicant: UNIVERSITY OF MARYLAND, COLLEGE PARK OFFICE OF TECHNOLOGY COMMERCIALIZATION

Inventor： BARAS, John S. ,  WENG, Xiangnan

IPC: G06Q30/02 ,  G06Q30/06

CPC classification number: G06Q30/0202 ,  G06F9/542 ,  G06Q30/0207 ,  G06Q30/0231 ,  G06Q30/0235 ,  G06Q50/01 ,  H04L67/04 ,  H04L67/22

Abstract: Various communication systems may benefit from optimized delivery or dissemination of information. For example, various wireless networks including heterogeneous wireless may benefit from joint optimization for social content delivery or dissemination over such networks. A method can include selecting content to deliver according to user reward values given wireless capacity constraints. The method can also include delivering the content to a plurality of users via a wireless network comprising different transmission modes.

Abstract translation: 各种通信系统可能受益于优化的信息传递或传播。 例如，包括异构无线的各种无线网络可以受益于通过这种网络进行社交内容传递或传播的联合优化。 一种方法可以包括根据给定无线容量约束的用户奖励值来选择要递送的内容。 该方法还可以包括经由包括不同传输模式的无线网络将内容递送给多个用户。

公开(公告)号：WO2015160706A1

公开(公告)日：2015-10-22

申请号：PCT/US2015/025576

申请日：2015-04-13

Applicant: UNIVERSITY OF MARYLAND, COLLEGE PARK OFFICE OF TECHNOLOGY COMMERCIALIZATION ,  CHILDREN'S NATIONAL MEDICAL CENTER

Inventor： BEHRENS, Adam ,  KOFINAS, Peter ,  SIKORSKI, Michael ,  SANDLER, Anthony ,  SRINIVASAN, Priya ,  LEE, Nora

IPC: A61K9/00 ,  A61K9/56 ,  A61K9/70

CPC classification number: A61L24/043 ,  A61L24/0015 ,  A61L27/26 ,  A61L27/54 ,  C08L71/02 ,  C08L67/04

Abstract: Compositions comprising biomedical polymers, and in particular unique blends of poly(lactic-co-glycolic acid) (PLGA) and poly(ethylene glycol) (PEG) are provided. Methods of forming polymer fibers using such compositions and solution blow spinning techniques are also provided, as well as methods of delivering the blow spun polymer fibers onto a surface (e.g., such as tissue for use as a surgical scaffold, sealant or tissue adhesive).

Abstract translation: 提供包含生物医学聚合物的组合物，特别是聚（乳酸 - 共 - 乙醇酸）（PLGA）和聚（乙二醇）（PEG）的独特混合物。 还提供了使用这种组合物形成聚合物纤维的方法和溶液吹塑技术，以及将吹塑聚合物纤维递送到表面（例如用作外科手术架，组织粘合剂的组织等）上的方法。

公开(公告)号：WO2014160136A1

公开(公告)日：2014-10-02

申请号：PCT/US2014/025896

申请日：2014-03-13

Applicant: UNIVERSITY OF MARYLAND, OFFICE OF TECHNOLOGY COMMERCIALIZATION

Inventor： DIEHN, Kevin ,  DOWLING, Matthew ,  RAGHAVAN, Srinivasa R. ,  KING, David R.

IPC: C09K3/00

CPC classification number: A61K31/734 ,  A61K31/717 ,  A61K31/722 ,  A61K38/39

Abstract: A hemostatic putty for treatment of a variety of wounds topographies, including but not limited to highly three dimensional wounds, for example gunshot wounds and impalements, is disclosed. The putty is comprised of a matrix polymer weakly crosslinked or not crosslinked such that a viscoelastic matrix is formed. The viscoelastic nature of the putty is tunable by the composition and enables the putty to conform to a variety of wound topographies. Likewise, a hemostatic polymer, for example chitosan or hydrophobically modified chitosan, is included in this matrix to impart hemostatic properties and tissue adhesive on the putty. The hemostatic polymers disclosed prevent microbial infection and are suitable for oxygen transfer required during normal wound metabolism.

Abstract translation: 公开了用于治疗各种伤口形态的止血腻子，包括但不限于高度三维伤口，例如枪伤和刺痛。 油灰由弱交联或未交联的基质聚合物组成，使得形成粘弹性基质。 腻子的粘弹性可以通过组合物调节，并使油灰符合各种伤口形貌。 同样地，在该基质中包含止血聚合物，例如壳聚糖或疏水改性的壳聚糖，以在腻子上提供止血性质和组织粘合剂。 所公开的止血聚合物防止微生物感染，并且适合于正常伤口代谢期间所需的氧传递。

公开(公告)号：WO2013040265A1

公开(公告)日：2013-03-21

申请号：PCT/US2012/055244

申请日：2012-09-13

Applicant: BRIGHAM YOUNG UNIVERSITY TECHNOLOGY COMMERCIALIZATION OFFICE ,  GENBERG, Carl ,  SAVAGE, Paul, B.

Inventor： GENBERG, Carl ,  SAVAGE, Paul, B.

IPC: A61K31/575 ,  A61K45/06 ,  A61P19/08 ,  A61P19/10 ,  A61P31/00

CPC classification number: A61K31/575

Abstract: Disclosed herein are methods of promoting osteogenesis in a subject, comprising administering a composition comprising a therapeutically effective amount of at least one cationic steroid antimicrobial (CSA). Also disclosed herein are methods of promoting osteogenesis in a subject in need of such promotion, comprising administering a composition comprising a therapeutically effective amount of at least one CSA. Additionally, disclosed herein are compounds and compositions comprising at least one CSA, or a pharmaceutically acceptable salt thereof, for use in the treatment of bone disease or the treatment of broken bones. Kits comprising such compositions and instructions on such methods are also contemplated herein.

Abstract translation: 本文公开了促进受试者成骨的方法，包括施用包含治疗有效量的至少一种阳离子类固醇抗微生物剂（CSA）的组合物。 本文还公开了在需要这种促进的受试者中促进成骨的方法，包括施用包含治疗有效量的至少一种CSA的组合物。 此外，本文公开了包含至少一种CSA或其药学上可接受的盐的化合物和组合物，其用于治疗骨疾病或治疗骨折。 本文还考虑了包含这些组合物的组合物和关于这些方法的说明书。

公开(公告)号：WO2010062682A1

公开(公告)日：2010-06-03

申请号：PCT/US2009/062758

申请日：2009-10-30

Applicant: OFFICE OF TECHNOLOGY COMMERCIALIZATION

Inventor： GUPTA, Ashwani

IPC: B01D53/52 ,  B01J19/24 ,  C01B17/04

CPC classification number: B01D53/52 ,  B01D2251/102 ,  C01B17/0413 ,  C01B17/0417 ,  Y02P20/129

Abstract: A method and system are presented for the combustion of hydrogen sulfide mixed with other gases for simultaneous recovery of sulfur and energy from hydrogen sulfide at higher efficiency. The amounts and velocity of the hydrogen sulfide into the reactor is selected in such a way that it is not possible to burn the hydrogen sulfide in a normal thin reaction zone during its combustion that normally prevails in almost all flame combustion devices. The injected hydrogen sulfide gas is mixed in a thermal reactor with fresh air and hot active combustion gases in the reactor on account of internal jet pump effect and self-induced entrainment. The reaction is exothermic so that the chemical energy present in hydrogen sulfide is recovered together with the sulfur that is tapped off from he process. The reactor process can also be used for other gas and chemicals that require controlled reactor thermo-chemical environment. Various reactors are shown capable of controlling the formation of a thermal distribution flow pattern based on the position and position and direction (and other factors) regarding fluid introduction within a combustion chamber of the reactors.

Abstract translation: 提出了与其他气体混合的硫化氢燃烧的方法和系统，以更高的效率同时从硫化氢中回收硫和能量。 选择硫化氢进入反应器的量和速度，使得在几乎所有火焰燃烧装置中通常普遍存在的燃烧过程中，不可能在正常的薄反应区中燃烧硫化氢。 注入的硫化氢气体在热反应器中与新鲜空气和热活性燃烧气体在反应器中混合，这是由于内部喷射泵效应和自身引发的夹带。 反应是放热的，因此存在于硫化氢中的化学能与从其过程中被分离的硫一起回收。 反应器工艺也可用于需要受控反应堆热化学环境的其他气体和化学品。 示出了各种反应器能够基于关于在反应器的燃烧室内的流体引入的位置和位置和方向（和其他因素）来控制形成热分布流动模式。

公开(公告)号：WO2008033330A3

公开(公告)日：2008-12-18

申请号：PCT/US2007019708

申请日：2007-09-11

Applicant: TECHNOLOGY COMMERCIALIZATION U ,  HUTCHESON STEVEN WAYNE ,  WEINER RONALD M

Inventor： HUTCHESON STEVEN WAYNE ,  WEINER RONALD M

IPC: C12P7/06 ,  C07K1/00 ,  C12N9/00 ,  C12N9/14 ,  C12N9/24

CPC classification number: C12N9/2437 ,  C12P19/14 ,  C12Y302/01004 ,  Y02E50/16 ,  Y02E50/17

Abstract: The present invention relates to cell wall degradative systems, in particular to systems containing enzymes that bind to and/or depolymerize cellulose. These systems have a number of applications. Some embodiments relate to a method of producing ethanol using the cell wall degradative systems of the present invention.

Abstract translation: 本发明涉及细胞壁降解系统，特别涉及含有结合纤维素和/或解聚纤维素的酶的体系。 这些系统有许多应用。 一些实施方案涉及使用本发明的细胞壁降解系统生产乙醇的方法。

公开(公告)号：WO2008094801A3

公开(公告)日：2008-10-09

申请号：PCT/US2008051806

申请日：2008-01-23

Applicant: TECHNOLOGY COMMERCIALIZATION

Inventor： GANELIN BORIS ,  KENWORTHY MICHAEL W

IPC: F04D29/041

CPC classification number: F01D3/00 ,  F01D11/02 ,  F04D29/0416 ,  F04D29/046 ,  F04D29/0513 ,  F04D29/056 ,  F05D2240/52 ,  F05D2240/53

Abstract: A method and apparatus to reduce the axial thrust in rotary machines such as compressors, centrifugal pumps, turbines, etc. includes providing additional peripheral restrictive means (7) attached at the peripheral portion of the disk forming the subdividing means (4) on the side facing the rotating rotor (2). An additional ring element at the periphery of the subdividing means forms additional radial (11) and axial restrictive means (15). Such peripheral restrictive means (7, 11 and 15) function as sealing dams, which combined with the outward flow induced by the rotating impeller, form self-pressurizing hydrodynamic bearings in the axial and radial planes, improving rotordynamic stability. Additionally, a stationary ring element in the center of the cavity forms a seal with the rotor, reducing leakage to suction.

Abstract translation: 一种用于减小诸如压缩机，离心泵，涡轮机等旋转机械中的轴向推力的方法和装置包括提供附加在盘的周边部分处的附加的外围限制装置（7），所述外围限制装置形成在侧面上的细分装置（4） 面向旋转转子（2）。 在分割装置的周边处的另外的环形元件形成附加的径向（11）和轴向限制装置（15）。 这种外围限制装置（7,11和15）用作密封坝，其结合由旋转叶轮引起的向外流动，在轴向和径向平面中形成自加压流体动力轴承，从而提高转动动力学稳定性。 另外，空腔中心的固定环元件与转子形成密封，减少了泄漏到吸力。

公开(公告)号：WO2004038765A2

公开(公告)日：2004-05-06

申请号：PCT/US2003/033830

申请日：2003-10-23

Applicant: CENTER FOR SCIENCE & TECHNOLOGY COMMERCIALIZATION ,  OPEL, INC.

Inventor： DEHMUBED, Rohinton ,  TAYLOR, Geoff, W. ,  UPP, Daniel, C. ,  CAI, Jianhong

IPC: H01L

CPC classification number: H01L29/66318 ,  H01L29/155 ,  H01L29/66462 ,  H01L29/802 ,  H03K3/42 ,  H03K17/79 ,  H03M1/667 ,  H03M1/74 ,  H03M1/808

Abstract: An optoelectronic device is provided that includes a thyristor detector/emitter device having an input port and an output port. The thyristor detector/emitter device is adapted to detect an input optical pulse supplied to the input port and to produce an output optical pulse (via laser emission) and an output electrical pulse in response to the detected input optical pulse. The output optical pulse is output via the output port. An optical feedback path is operably coupled between the output port and the input port of the thyristor detector/emitter device. The optical feedback path supplies a portion of the output optical pulse produced by the thyristor detector/emitter device to the input port, thereby causing the thyristor detector/emitter device to produce a sequence of output optical pulses and a corresponding sequence of output electrical pulses. Preferably, the optical feedback path comprises a programmable optical delay line realized by a network of in-plane waveguide structures and directional coupler devices that are integrally formed with the thyristor device structure of the detector/emitter device. Other optoelectronic devices are realized with the thyristor detector/emitter.

Abstract translation: 提供了一种光电子器件，其包括具有输入端口和输出端口的晶闸管检测器/发射器装置。 晶闸管检测器/发射器件适于检测提供给输入端口的输入光脉冲，并响应于检测到的输入光脉冲产生输出光脉冲（经由激光发射）和输出电脉冲。 输出光脉冲通过输出端口输出。 光学反馈路径可操作地耦合在晶闸管检测器/发射器件的输出端口和输入端口之间。 光学反馈路径将由晶闸管检测器/发射器件产生的输出光脉冲的一部分提供给输入端口，从而使晶闸管检测器/发射器件产生一系列输出光脉冲和相应的输出电脉冲序列。 优选地，光学反馈路径包括由面内波导结构的网络和与检测器/发射器件的晶闸管器件结构整体形成的定向耦合器件实现的可编程光学延迟线。 其他光电子器件由晶闸管检测器/发射器实现。

公开(公告)号：WO2004038764A2

公开(公告)日：2004-05-06

申请号：PCT/US2003/033829

申请日：2003-10-23

Applicant: CENTER FOR SCIENCE & TECHNOLOGY COMMERCIALIZATION ,  OPEL, Inc.

Inventor： TAYLOR, Geoff, W. ,  DUNCAN, Scott, W.

IPC: H01L

CPC classification number: H01L29/66318 ,  H01L27/0605 ,  H01L29/155 ,  H01L29/66462 ,  H01L29/7371 ,  H01L29/802

Abstract: A semiconductor device includes a series of layers formed on a substrate, the layers including a first plurality of layers including an n-type ohmic contact layer, a p-type modulation doped quantum well structure, an n-type modulation doped quantum well structure, and a fourth plurality of layers including a p-type ohmic contact layer. Etch stop layers are used to form contacts to the n-type ohmic contact layer and contacts to the n-type modulation doped quantum well structure. Thin capping layers are also provided to protect certain layers from oxidation. Preferably, each such etch stop layer is made sufficiently thin to permit current tunneling therethrough during operation of optoelectronic/electronic devices realized from this structure (including heterojunction thyristor devices, n-channel HFET devices, p-channel HFET devices, p-type quantum-well-base bipolar transistor devices, and n-type quantum-well-base bipolar transistor devices). In another aspect of the present invention, a high performance bipolar transistor device is realized from this structure by implanting p-type ions in a interdigitization pattern that forms a plurality of p-type ion implant regions on both sides of the p-type modulation doped quantum well structure to a depth that penetrates the n-type ohmic contact layer. The interdigitization pattern of the p-type implants reduces capacitance between the p-type modulation doped quantum well structure and the n-type ohmic contact layer to enable higher frequency operation.

Abstract translation: 半导体器件包括在衬底上形成的一系列层，所述层包括包括n型欧姆接触层，p型调制掺杂量子阱结构，n型调制掺杂量子阱结构的第一多个层， 以及包括p型欧姆接触层的第四多个层。 蚀刻停止层用于形成与n型欧姆接触层的接触并与n型调制掺杂量子阱结构接触。 还提供薄盖层以保护某些层免于氧化。 优选地，每个这样的蚀刻停止层被制成足够薄，以便在从该结构实现的光电子/电子器件的操作期间（包括异质结晶闸管器件，n沟道HFET器件，p沟道HFET器件，p型量子阱器件） 基极双极晶体管器件和n型量子阱基双极晶体管器件）。 在本发明的另一方面，通过将p型离子注入到在p型调制掺杂的两侧上形成多个p型离子注入区的叉指形式中，从该结构实现了高性能双极晶体管器件 量子阱结构到穿透n型欧姆接触层的深度。 p型植入物的叉​​指形式降低p型调制掺杂量子阱结构和n型欧姆接触层之间的电容，以实现更高频率的操作。