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    A MULTI-CHANNEL ELECTROPHYSIOLOGIC SIGNAL DATA ACQUISITION SYSTEM ON AN INTEGRATED CIRCUIT
    72.
    发明申请
    A MULTI-CHANNEL ELECTROPHYSIOLOGIC SIGNAL DATA ACQUISITION SYSTEM ON AN INTEGRATED CIRCUIT 审中-公开
    集成电路上的多通道电生理信号数据采集系统

    公开(公告)号：WO2006050325A2

    公开(公告)日：2006-05-11

    申请号：PCT/US2005/039383

    申请日：2005-10-28

    Applicant: WORCESTER POLYTECHNIC INSTITUTE ,  CLANCY, Edward, A. ,  MCNEILL, John, A. ,  MICHALSON, William, R.

    Inventor： CLANCY, Edward, A. ,  MCNEILL, John, A. ,  MICHALSON, William, R.

    IPC: G06F19/00

    CPC classification number: A61B5/04 ,  A61B5/04004 ,  A61B5/0428 ,  A61B5/0476 ,  A61B5/0488 ,  A61B5/0496 ,  A61B5/7242 ,  G06F19/00 ,  G16H40/63

    Abstract: A physiologic data acquisition system includes an analog input, a sigma-delta front end signal conditioning circuit adapted to subtract out DC and low frequency interfering signals from and amplify the analog input before analog to digital conversion. The system can be programmed to acquire a selected physiologic signal, e.g., a physiologic signal characteristic of or originating from a particular biological tissue. The physiologic data acquisition system may include a network interface modulating a plurality of subcarriers with respective portions of an acquired physiologic signal. A receiver coupled to the network interface can receive physiologic data from, and send control signals and provide power to the physiologic data acquisition system over a single pair of wires. The network interface can modulate an RF carrier with the plurality of modulated subcarriers and transmit the resulting signal to the receiver across a wireless network. An integrated circuit may include the physiologic data acquisition system. Also included are methods for acquiring physiologic data comprising the step of selectively controlling an acquisition circuit to acquire the physiologic signal.

    Abstract translation: 生理数据采集系统包括模拟输入，Σ-Δ前端信号调理电路，适于在模数转换之前减去DC和低频干扰信号并放大模拟输入。 该系统可以被编程以获取所选择的生理信号，例如特定生物组织的特征或源自特定生物组织的生理信号。 生理数据采集系统可以包括利用获取的生理信号的各个部分来调制多个子载波的网络接口。 耦合到网络接口的接收器可以接收生理数据并发送控制信号，并通过单根线对生理数据采集系统提供电力。 网络接口可以利用多个经调制的子载波来调制RF载波，并通过无线网络将结果信号发送到接收机。 集成电路可以包括生理数据采集系统。 还包括用于获取生理数据的方法，包括选择性地控制采集电路以获取生理信号的步骤。

    VARIABLE FORCE ENERGY DISSIPATER AND DECELERATOR
    73.
    发明申请
    VARIABLE FORCE ENERGY DISSIPATER AND DECELERATOR 审中-公开

    公开(公告)号：WO2003102402A3

    公开(公告)日：2003-12-11

    申请号：PCT/US2003/017435

    申请日：2003-05-30

    Applicant: WORCESTER POLYTECHNIC INSTITUTE

    Inventor： RAY, Malcolm ,  PLAXICO, Chuck

    IPC: F16F7/12

    Abstract: Tunable pull-through energy attenuator and decelerator devices is disclosed which provide for variable force-time profiles, deceleration and kinetic energy attenuation of moving objects so as to prevent damage or injury to impacting objects, vehicles or persons. The device employs either consumable inelastic or reusable, viscoelastic deforming elements, such as tubes, rods, plates or strips, which absorb substantial amounts of energy through repeated inelastic or viscoelastic deformation when the deforming element is pulled through a tunable array of rigid pins having a variety of configurations and settings. The disclosed devices provide for variable force-time profiles which control the cumulative deformation and thereby the amount of energy absorbed and rate of deceleration of impacting objects. The device may be readily adapted and deployed as highway vehicle guardrails, road barriers or crash cushions for frontal and side impacts and as load attenuators for crash-resistant aircraft seats, spacecraft landing pods, crash-resistant aircraft landing gear, aircraft and vehicle passenger restraint harnesses, cargo tie-downs, vehicle bumpers and collapsible vehicle steering columns.

    DNA MARKERS FOR SHRIMP SELECTION
    74.
    发明申请
    DNA MARKERS FOR SHRIMP SELECTION 审中-公开
    用于SHRIMP选择的DNA标记

    公开(公告)号：WO1997021835A2

    公开(公告)日：1997-06-19

    申请号：PCT/US1996019568

    申请日：1996-12-12

    Applicant: WORCESTER POLYTECHNIC INSTITUTE

    Inventor： WORCESTER POLYTECHNIC INSTITUTE ,  BAGSHAW, Joseph, C. ,  BUCKHOLT, Michael, A.

    IPC: C12Q01/68

    CPC classification number: C12Q1/6888 ,  C12Q2600/156

    Abstract: Isolated DNA from Penaeus vannamei was digested with restriction enzymes, restriction fragments of genomic DNA inserted into a plasmid vector and screened for recombinant plasmids containing repeated sequences. Ten of the resulting isolates contained representatives of the same repeated element, a satellite sequence present in one or more blocks of tandemly repeated units. The cloned repeat units range in size from about 100 to 200 base pairs, more typically between about 139 to 188 base pairs. Embedded within each cloned repeat unit are 6 to 15 copies of a tandemly repeated pentanucleotide microsatellite. The genome of P. vannamei contains approximately one million copies of this satellite/microsatellite unit. The sequences are useful as markers for the selection of shrimp having a genetically-transmitted favorable growth characteristic, such as increased reproduction, enhanced growth rate, increased size, disease-resistance, and the ability to grow in colder waters, for improved aquacultured shrimp production. Hybridization of the marker to an isolated Peaneus shrimp mucleic acid molecule can be used to identify species, strains or individual shrimp having the desired characteristics. Once identified, these shrimps can be bred to shrimp having the same or an additional desired characteristic to produce a high quality, genetically superior seedstock or larvae useful for the economic production of farmed shrimp.

    Abstract translation: 用限制性酶，基因组DNA的限制性片段插入到质粒载体中消化来自对虾（Penaeus vannamei）的分离的DNA，并筛选含有重复序列的重组质粒。 所产生的分离物中的10个包含相同重复元件的代表，卫星序列存在于一个或多个串联重复单元的块中。 克隆的重复单元的大小范围为约100至200个碱基对，更典型地在约139至188个碱基对之间。 嵌入每个克隆的重复单元中是6至15个拷贝的串联重复的五核苷酸微卫星。 凡纳滨对虾的基因组包含该卫星/微型卫星单位约100万份。 这些序列可用作选择具有遗传转化的有利生长特征的虾的标记物，例如增加繁殖，增强生长速率，增加的大小，抗病性以及在较冷的水中生长的能力，以改善水产养殖虾生产 。 标记物与分离的豌豆虾核酸分子的杂交可以用于鉴定具有所需特征的物种，菌株或个体虾。 一旦鉴定出来，这些虾可以养殖到具有相同或额外的期望特性的虾，以产生用于经济生产养殖虾的高质量，遗传优良的种子或幼体。

    ATOMIZING SPRAY DRYER
    75.
    发明申请
    ATOMIZING SPRAY DRYER 审中-公开

    公开(公告)号：WO2023275805A1

    公开(公告)日：2023-01-05

    申请号：PCT/IB2022/056082

    申请日：2022-06-29

    Applicant: WORCESTER POLYTECHNIC INSTITUTE

    Inventor： YAGOOBI, Jamal S. ,  YANG, Mengqiao ,  DARDASHTI, Mehrnoosh F.

    IPC: B01J2/02 ,  B01J2/18 ,  B01J19/10 ,  B01D1/18 ,  B01D1/20

    Abstract: An atomizing spray dryer employs one or more stages defined by ultrasonic transducers in close proximity to a liquid feed opening forming a path of an atomization flow for producing uniform droplets from a close tolerance with the transducer. The atomization flow exits a gap between the transducer and an outer edge of the opening, such that the passed liquid is responsive to an oscillation of the transducer for forming the droplets. A conical or other suitably shaped transducer engages a substantially round liquid feed opening. Subsequent stages may include a circular, ring, or other suitable shape aligned to receive the atomization flow from a circumference of the conical base, or may also take any suitable shape, preferably to receive droplets directed by the first stage.

    OPTICAL FIBER SENSORS
    76.
    发明申请
    OPTICAL FIBER SENSORS 审中-公开

    公开(公告)号：WO2022164845A1

    公开(公告)日：2022-08-04

    申请号：PCT/US2022/013814

    申请日：2022-01-26

    Applicant: WORCESTER POLYTECHNIC INSTITUTE

    Inventor： LIU, Yuxiang ,  RAO, Pratap ,  REN, Yundong ,  LI, Mucheng

    IPC: G01N21/3554 ,  G01N21/3504

    Abstract: A fiber optic sensing device includes an optical fiber having a polished end defining a flat sensory portion coated with a lossy-mode-resonance (LMR) coating. A reflective coating on an end face of the optical fiber facilitates propagation of a return signal. An optic circuit for identifies a wavelength attenuated by the LMR coating from the return signal reflected by the reflective coating based on a moisture presence at the sensory portion. Various gaseous parameters may be detected based on the coating on the sensory portion. An LMR coating of tin oxide (SnO2) is employed for moisture sensing.

    WEARABLE BLOOD GAS MONITOR
    78.
    发明申请
    WEARABLE BLOOD GAS MONITOR 审中-公开

    公开(公告)号：WO2021072144A1

    公开(公告)日：2021-04-15

    申请号：PCT/US2020/054900

    申请日：2020-10-09

    Applicant: WORCESTER POLYTECHNIC INSTITUTE

    Inventor： GULER, Ulkuhan ,  COSTANZO, Ian ,  SEN, Devdip ,  RHEIN, Lawrence

    IPC: A61B5/1455

    Abstract: A transdermal oxygen patch measures an oxygen concentration based on transcutaneous oxygen diffusing through an epidermal surface of a patient. Transcutaneous oxygen differs from hemoglobin-bound oxygen often measured in a patient blood flow. The patch employs an indicator responsive to an oxygen presence for emitting light having an intensity and lifetime (duration) based on the oxygen presence. An optical receptor is in communication with logic for receiving the intensity of emitted light and computing the oxygen concentration based on the received intensity and lifetime (duration). A wireless transmitter conveys the results to a base station or monitoring counterpart for untethered patient monitoring. Low power demands and circuit footprint are amenable to a wearable device such as a patch for continuous use.

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