Abstract:
본 발명은 (a) 알칼라아제, 알카라인 프로테아제 및 이들의 조합으로 구성된 군으로부터 선택되는 단백질 분해효소를 곡물과 접촉시키는 단계; 및 (b) 상기 단계 (a)의 결과물에 80-200℃의 열을 가하는 단계를 포함하는 곡물의 알레르기 항원성을 저감시키는 방법에 관한 것이다. 본 발명에 따르면 알칼라아제, 알카라인 프로테아제 및 이들의 조합으로 구성된 군으로부터 선택되는 단백질 분해효소 및 80-200℃의 열을 가하여 곡물, 특히 쌀의 알레르기 항원성을 대부분 제거할 수 있다. 따라서 본 발명은 식품알레르기 원인 식품, 특히 쌀에 의한 알레르기 질환의 예방에 크게 기여할 수 있다.
Abstract:
The present invention relates to a composition for preventing, alleviating, or treating Th2-mediated immune diseases, the composition containing, as an active ingredient, a natural extract of at least one natural extract selected from the group consisting of Wolfiporia cocos, Phellodendron amurense, and Achyranthes japonica. According to the present invention, the natural extract has an effect of inhibiting the generation of IL-4 generation and the degranulation of mast cells, and thus can prevent, alleviate, or treat Th2-mediated diseases.
Abstract:
The present invention relates to a composition comprising Solani nigri herba extract, Dictamni radices cortex extract, or its combination as an active ingredient for preventing, alleviating, or treating Th1-mediated immune disease or Th2-mediated immune disease. According to the present invention, the Solani nigri herba extract and/or the Dictamni radices cortex extract has a differentiation-inducing activity to Treg cells, thereby can be used to prevent, alleviate, or treat Th1-mediated immune disease or Th2-mediated immune disease.
Abstract:
The present invention relates to a composition containing an extract of at least one natural substance selected from the group consisting of Benzoinum, Piperis nigri Fructus, Sophorae fructus, Akebiae caulis, and Tritici immatri Semen, as an active ingredient to prevent, alleviate, or treat Th1-mediated immune disease or Th2-mediated immune disease. According to the present invention, the extract of the natural substance induces the differentiation into Treg cells and has activity to stabilize Treg cells, thus can prevent, alleviate, or treat Th1-mediated immune disease or Th2-mediated immune disease.
Abstract:
The present invention relates to a composition comprising a Cynanchum atratum Bunge extract as an active ingredient for preventing, alleviating, or treating Th1-mediated immune diseases or Th2-mediated immune diseases. According to the present invention, the Cynanchum atratum Bunge extract has activities of preventing allergen from passing through intestinal epithelial cells, inhibiting production of IL-4, inhibiting degranulation of mast cells, inducing differentiation into Treg cells, and stabilizing Treg cells, thereby preventing, alleviating, or treating Th1-mediated immune diseases or Th2-mediated immune diseases.