公开(公告)号：AT168010T

公开(公告)日：1998-07-15

申请号：AT94904432

申请日：1993-12-10

Applicant: BAXTER INT

Inventor： MARTIS LEO ,  BURKE RON ,  FAICT DIRK

IPC: A61K9/08 ,  A61K31/70 ,  A61K33/00 ,  A61K38/00 ,  A61K38/01 ,  A61K38/02 ,  A61K47/26 ,  A61K47/42 ,  A61M1/14 ,  A61M1/28 ,  A61P7/08

Abstract: The solution contains as osmotic agents both dectrose and polypeptides. The polypeptides are synthetic and are 4 to 10 amino acids long.

公开(公告)号：SG48090A1

公开(公告)日：1998-04-17

申请号：SG1996006963

申请日：1994-01-18

Applicant: BAXTER INT

Inventor： BALTEAU PATRICK ,  FAICT DIRK ,  PELUSO FRANCESCO

IPC: B65D81/32 ,  A61J1/00 ,  A61J1/10 ,  A61J1/20 ,  A61M1/28 ,  B65D30/22

Abstract: A multiple chamber container for mixing and administering a plurality of products. The container has at least two chambers separated by a seal line. A frangible connector is situated between the two chambers for mixing the products contained within the chambers as desired. Each chamber has at least one port for filling of product into the chamber. The ports are located on the same exterior side of the container such that the chambers can be filled without folding the bag and by using existing filling equipment.

公开(公告)号：DE69407527D1

公开(公告)日：1998-02-05

申请号：DE69407527

申请日：1994-03-17

Applicant: BAXTER INT

Inventor： SEGERS ALAIN ,  FAICT DIRK ,  DUPONCHELLE ANNICK ,  HARTMAN JEAN-PIERRE ,  PELUSO FRANCESCO

IPC: A61J1/05 ,  A61J1/00 ,  A61J1/14 ,  A61J1/20 ,  A61J3/00 ,  A61K33/00 ,  A61M1/14 ,  A61M1/16 ,  A61M1/28 ,  A61P3/00 ,  C01B32/60

Abstract: A method and device for stabilizing and storing bicarbonate solutions is provided. In an embodiment, a device is provided having a container and carbon-dioxide generating substances that include a solid material which upon contact with water generates carbon-dioxide gas. The device may be packaged together with the bicarbonate or in a separate overpouch. The present invention also provides a method for the stabilization of bicarbonate solutions utilizing a means that generates high pressure carbon dioxide.

公开(公告)号：DE69403572D1

公开(公告)日：1997-07-10

申请号：DE69403572

申请日：1994-01-18

Applicant: BAXTER INT

Inventor： BALTEAU PATRICK ,  FAICT DIRK ,  PELUSO FRANCESCO

IPC: B65D81/32 ,  A61J1/00 ,  A61J1/10 ,  A61J1/20 ,  A61M1/28 ,  B65D30/22

Abstract: A multiple chamber container for mixing and administering a plurality of products. The container has at least two chambers separated by a seal line. A frangible connector is situated between the two chambers for mixing the products contained within the chambers as desired. Each chamber has at least one port for filling of product into the chamber. The ports are located on the same exterior side of the container such that the chambers can be filled without folding the bag and by using existing filling equipment.

公开(公告)号：CA2399440A1

公开(公告)日：1997-03-06

申请号：CA2399440

申请日：1996-08-27

Applicant: BAXTER INT

Inventor： PELUSO FRANCESCO ,  FAICT DIRK ,  COLLERAN LISA ,  CHEN CHI J ,  EMERSON PAUL FREDERICK ,  CHILDERS ROBERT WARREN ,  BALTEAU PATRICK ,  EERLINGEN VITAL

IPC: A61M1/28

Abstract: A system and a method are provided for admixing solutions. The system includes containers separately accessible by one or more pumps for mixture of the solutions in a container immediately before administration to a peritoneal cavity of a patient. Alternatively, the system and method allow for direct administration of the mixed solution to the peritoneal cavity of a patient without intermediate mixing thereof. The solutions may be mixed in predetermined ratios as input to the system prior to delivery.

公开(公告)号：CA2045610C

公开(公告)日：1996-03-12

申请号：CA2045610

申请日：1990-11-28

Applicant: BAXTER INT

Inventor： FAICT DIRK ,  PELUSO FRANCESCO ,  BALTEAU PATRICK

IPC: A61M1/14 ,  A61M1/28 ,  A61K31/40 ,  A61K31/195 ,  A61K47/22

Abstract: A peritoneal dialysis solution buffered with L-histidine to a pH of at least 6.5. An apparatus and method for utilizing the solution is also disclosed.

公开(公告)号：AU2021595A

公开(公告)日：1995-08-10

申请号：AU2021595

申请日：1995-05-22

Applicant: BAXTER INT

Inventor： BALTEAU PATRICK ,  FAICT DIRK ,  PELUSO FRANCESCO

IPC: B65D81/32 ,  A61J1/00 ,  A61J1/10 ,  A61J1/20 ,  A61M1/28 ,  B65D30/22 ,  B65B3/04 ,  B65B29/10 ,  B65D25/08

Abstract: A multiple chamber container for mixing and administering a plurality of products. The container has at least two chambers separated by a seal line. A frangible connector is situated between the two chambers for mixing the products contained within the chambers as desired. Each chamber has at least one port for filling of product into the chamber. The ports are located on the same exterior side of the container such that the chambers can be filled without folding the bag and by using existing filling equipment.

公开(公告)号：BR9007084A

公开(公告)日：1991-12-24

申请号：BR9007084

申请日：1990-11-28

Applicant: BAXTER INT

Inventor： FAICT DIRK ,  PELUSO FRANCESCO ,  BALTEAU PATRICK

IPC: A61M1/14 ,  A61M1/28 ,  A61K37/18

Abstract: A peritoneal dialysis solution buffered with L-histidine to a pH of at least 6.5. An apparatus and method for utilizing the solution is also disclosed.

公开(公告)号：DK2322236T5

公开(公告)日：2013-03-11

申请号：DK10075490

申请日：2002-11-04

Applicant: BAXTER INT

Inventor： ELISABETTINI PAOLA ,  MENNEGUERRE JEAN-PAUL ,  COLAS JEROME ,  RENAUX CHRISTIAN ,  FAICT DIRK ,  WILMET ISABELLE ,  DIVINO JOSE

IPC: A61K9/08 ,  A61M1/28 ,  A61K33/14 ,  A61M1/14 ,  A61P13/12

公开(公告)号：CA2352561C

公开(公告)日：2009-02-10

申请号：CA2352561

申请日：2000-07-27

Applicant: BAXTER INT

Inventor： BALTEAU PATRICK ,  MARTIS LEO ,  HARTMAN JEAN-PIERRE ,  FAICT DIRK ,  PELUSO FRANCESCO ,  DUPONCHELLE ANNICK

IPC: A61J3/00 ,  A61K33/10 ,  A61J1/05 ,  A61J1/10 ,  A61J1/20 ,  A61K31/19 ,  A61K33/06 ,  A61K33/14 ,  A61M1/14 ,  A61M1/16 ,  A61M1/28 ,  A61M1/34 ,  A61P13/12

Abstract: The present invention provides devices and methods for stabilizing bicarbona te- based solutions for peritoneal dialysis or hemofiltration. The bicarbonate-based solutions of the present invention are formulated and stored in at least two parts - an alkaline bicarbonate concentrate and an acidic concentrate. The alkaline bicarbonate concentrate is adjusted to have a pH of about 8.6 to 10.0. The acidic concentrate is adjusted to have a stable, acidic pH ranging from about 1.0 to 3.0. Upon mixing, although some variation in the pH of the mixed bicarbonate solution exists, the inventors have discovered that with the appropriate selection of the parameters of the concentrates, the pH of the mixed solution is alway s within an acceptable physiological range.