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公开(公告)号：NO870078A
公开(公告)日：1987-07-10
申请号：NO870078
申请日：1987-01-08
Applicant: HOECHST AG
Inventor： RUEGER WOLFGANG , URBACH HANSJOERG , BARTMANN WILHELM , KAISER JOACHIM
IPC: A61K31/395 , A61K31/4427 , A61K31/445 , A61K31/4465 , A61K31/4468 , A61K31/451 , A61K31/47 , A61K31/472 , A61K31/495 , A61K31/55 , A61P3/00 , A61P3/14 , A61P9/00 , A61P9/08 , A61P9/10 , C07D211/18 , C07D211/22 , C07D211/48 , C07D211/58 , C07D211/70 , C07D215/20 , C07D215/22 , C07D215/227 , C07D215/26 , C07D217/02 , C07D217/04 , C07D217/06 , C07D223/04 , C07D223/12 , C07D225/02 , C07D241/04 , C07D243/08 , C07D295/073 , C07D295/08 , C07D295/088 , C07D295/092 , C07D295/096 , C07D401/12 , C07D401/00 , C07D241/00 , C07D403/00
CPC classification number: C07D215/227 , C07D211/18 , C07D211/22 , C07D211/58 , C07D215/20 , C07D215/26 , C07D217/02 , C07D217/04 , C07D217/06 , C07D241/04 , C07D243/08 , C07D295/073 , C07D295/088 , C07D295/096 , C07D401/12
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公开(公告)号：FI870056A
公开(公告)日：1987-07-10
申请号：FI870056
申请日：1987-01-07
Applicant: HOECHST AG
Inventor： RUEGER WOLFGANG , URBACH HANSJOERG , BARTMANN WILHELM , KAISER JOACHIM
IPC: A61K31/395 , A61K31/4427 , A61K31/445 , A61K31/4465 , A61K31/4468 , A61K31/451 , A61K31/47 , A61K31/472 , A61K31/495 , A61K31/55 , A61P3/00 , A61P3/14 , A61P9/00 , A61P9/08 , A61P9/10 , C07D211/18 , C07D211/22 , C07D211/48 , C07D211/58 , C07D211/70 , C07D215/20 , C07D215/22 , C07D215/227 , C07D215/26 , C07D217/02 , C07D217/04 , C07D217/06 , C07D223/04 , C07D223/12 , C07D225/02 , C07D241/04 , C07D243/08 , C07D295/073 , C07D295/08 , C07D295/088 , C07D295/092 , C07D295/096 , C07D401/12 , C07D
Abstract: Compounds I … … where R is equal to cycloalkyl, alkenyl, cycloalkenyl, phenyl, … … where B, C, D and E are equal to methine or nitrogen and… B', C', D' and E' are equal to methylene, carbonyl or imino;… R is equal to phenyl or phenylalkyl;… A is equal to various amine radicals;… m is equal to 2, 3 or 4; and… n is equal to 1, 2, 3 or 4;… salts of these compounds I are also described. Compounds I and the salts are calcium antagonists.
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公开(公告)号：DK114286A
公开(公告)日：1986-09-14
申请号：DK114286
申请日：1986-03-12
Applicant: HOECHST AG
Inventor： LAU HANS-HERMANN , BARTMANN WILHELM , BECK GERHARD , WESS GUENTHER
IPC: A61K31/44 , A61K31/4406 , A61K31/4418 , A61P7/02 , A61P43/00 , C07D213/26 , C07D213/30 , C07D213/42 , C07D213/50 , C07D213/53 , C07D213/55 , C07D
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公开(公告)号：DK114186D0
公开(公告)日：1986-03-12
申请号：DK114186
申请日：1986-03-12
Applicant: HOECHST AG
Inventor： LAU HANS-HERMANN , BARTMANN WILHELM , BECK GERHARD , WESS GUENTHER
IPC: A61K31/415 , A61P7/02 , C07D233/56 , C07D233/64 , C07D521/00 , C07D
Abstract: Compounds of the formula I I in which R1, R2 and Y have the indicated meanings, their physiologically tolerated acid addition salts, and a process for the preparation of these compounds are described. The compounds inhibit thromboxane synthetase and can thus be used as medicaments.
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公开(公告)号：DK381985A
公开(公告)日：1986-02-24
申请号：DK381985
申请日：1985-08-22
Applicant: HOECHST AG
Inventor： WESS GUENTHER , BARTMANN WILHELM , BECK GERHARD , LAU HANS-HERMANN
IPC: A61K31/44 , A61K31/4406 , A61K31/4418 , A61K31/443 , A61K31/4433 , A61P3/06 , A61P35/00 , A61P43/00 , C07D213/30 , C07D213/48 , C07D213/50 , C07D213/51 , C07D213/55 , C07D213/80 , C07D317/00 , C07D333/00 , C07D405/10 , C07D409/10 , C07D409/12 , C07F9/40 , C12N9/99 , C07D
Abstract: The present invention relates to new pyridines substituted in the 3-position, of the formula and to a process for their preparation. The compounds bring about specific inhibition of thromboxane synthetase and can thus be used as medicaments.
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Patent Agency Ranking
公开(公告)号：AU539763B2
公开(公告)日：1984-10-18
申请号：AU5490280
申请日：1980-01-24
Applicant: HOECHST AG
Inventor： BARTMANN WILHELM , KONZ ELMAR , LERCH ULRICH , SCHOLKENS BERNWARD
IPC: C07D307/935 , A61K31/34 , A61K31/343 , A61K31/557 , A61P7/02 , C07D307/937 , C07D407/08 , C07D409/08 , C07D409/12
Abstract: What is disclosed are prostacyclin analogs of the general formula I I which have a more specific action and/or a longer action than the naturally occurring prostacyclin PGI2, as well as intermediate products for their preparation and a process for their preparation. The compounds of formula I are distinguished by inhibitory action on thrombocyte aggregation and by relaxation of the vascular walls, in particular of the coronary arteries. They can thus be used as medicaments.
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公开(公告)号：PH16713A
公开(公告)日：1984-01-20
申请号：PH17517
申请日：1975-08-29
Applicant: HOECHST AG
Inventor： BECK GERHARD , BARTMANN WILHELM , LERCH ULRICH , SCHOLKENS BERNHARD
IPC: C07C61/06 , C07C69/66 , C07C69/74 , C07C177/00
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公开(公告)号：CA1152504A
公开(公告)日：1983-08-23
申请号：CA333330
申请日：1979-08-03
Applicant: HOECHST AG
Inventor： BARTMANN WILHELM , BECK GERHARD , LERCH ULRICH , KONZ ELMAR
IPC: A61K31/23 , A61K31/19 , A61K31/34 , A61K31/341 , A61K31/38 , A61K31/381 , A61K31/557 , A61P43/00 , C07C35/06 , C07C45/29 , C07C45/60 , C07C47/267 , C07C49/597 , C07C49/743 , C07C49/757 , C07C67/00 , C07C401/00 , C07C405/00 , C07D307/34 , C07D307/58 , C07D307/935 , C07D319/06 , C07D333/16 , C07D409/14 , C07C177/00 , C07D333/04 , C07D307/54
Abstract: of the disclosure: Compounds of the formula X which are structurally related to natural prostaglandins and process for their manufacture. The compounds have valuable pharmacological properties and, therefore, they can be used as medicaments.
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公开(公告)号：ZA8203113B
公开(公告)日：1983-03-30
申请号：ZA8203113
申请日：1982-05-06
Applicant: HOECHST AG
Inventor： BECK GERHARD , BARTMANN WILHELM , KNOLLE JOCHEN , RUPP RICHARD HELMUT
IPC: A61K31/40 , A61K31/4025 , A61P43/00 , C07D207/24 , C07D409/12 , C07D , A61K
CPC classification number: C07D207/24
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公开(公告)号：AU526681B2
公开(公告)日：1983-01-27
申请号：AU4648079
申请日：1979-04-26
Applicant: HOECHST AG
Inventor： BARTMANN WILHELM , KONZ ELMAR , GEYER HARRY MAURICE
IPC: A61K31/47 , A61K31/472 , A61P25/08 , A61P25/24 , A61P25/26 , C07D217/22 , C07D401/04 , C07D403/04 , C07D409/14 , A61K31/495 , A61K31/535 , A61K31/54 , C07D401/12 , C07D401/14 , C07D413/12 , C07D491/04
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