-
公开(公告)号：NZ186094A
公开(公告)日：1979-10-25
申请号：NZ18609477
申请日：1977-12-22
Applicant: HOECHST AG
Inventor： MUSCHAWECK R , MERKEL W , BORMANN D , MANIA D
IPC: A61K31/40 , A61P7/10 , C07D207/32 , C07D207/327 , C07D295/155 , C07D317/64
-
公开(公告)号：ZA781433B
公开(公告)日：1979-02-28
申请号：ZA781433
申请日：1978-03-10
Applicant: HOECHST AG
Inventor： SCHRINNER E , BORMANN D , KNABE B , WORM M
IPC: A61K31/44 , A61K31/535 , A61K31/545 , A61K31/546 , A61P31/04 , C07D277/20 , C07D277/38 , C07D277/40 , C07D463/00 , C07D501/20 , C07D505/00 , A61K31/00
Abstract: Cephem derivatives of the formula in which R1 denotes hydrogen or low-molecular alkoxy, R2 denotes hydrogen, optionally substituted alkyl, phthalide or a cation, X denotes sulfur, oxygen or CH2 and A denotes hydrogen, alkoxy, halogen or a group -CH2Y, in which Y represents hydrogen, acyloxy, alkoxy, optionally substituted carbamoyloxy or a group -SR3, in which R3 can represent acyl, alkyl or an optionally substituted 5-membered or 6-membered heterocyclic structure are disclosed as valuable antibiotics which are well suited for combating Gram-positive and in particular Gram-negative infections and also have an unexpectedly good action against penicillinase-forming staphylococci.
-
公开(公告)号：LU79350A1
公开(公告)日：1978-11-27
申请号：LU79350
申请日：1978-03-31
Applicant: HOECHST AG
Inventor： DUERCKHEIMER W , SCHRINNER E , HEYMES R , EHLERS E , BORMANN D
IPC: A61K31/397 , A61K31/435 , A61K31/505 , A61K31/535 , A61K31/545 , A61K31/546 , A61P31/04 , B25J15/08 , C07D205/08 , C07D277/20 , C07D277/40 , C07D277/42 , C07D277/50 , C07D463/00 , C07D471/04 , C07D487/04 , C07D498/04 , C07D501/20 , C07D501/24 , C07D501/36 , C07D505/00 , C07D519/06 , C07F9/6561 , C07D , A61K
-
公开(公告)号：SE404796B
公开(公告)日：1978-10-30
申请号：SE7504841
申请日：1975-04-25
Applicant: HOECHST AG
Inventor： BORMANN D , MERKEL W , MUSCHAWECK R , MANIA D
IPC: C07D207/04 , A61K20060101 , A61K31/125 , A61K31/18 , A61K31/33 , A61K31/395 , A61K31/40 , A61K31/402 , A61K31/445 , A61K31/45 , A61K31/635 , A61P7/10 , C07C20060101 , C07D20060101 , C07D205/04 , C07D207/02 , C07D207/06 , C07D207/08 , C07D207/10 , C07D207/18 , C07D207/20 , C07D207/32 , C07D207/327 , C07D207/40 , C07D207/404 , C07D207/44 , C07D209/00 , C07D209/44 , C07D209/48 , C07D209/52 , C07D209/94 , C07D211/04 , C07D211/14 , C07D211/18 , C07D211/30 , C07D211/32 , C07D211/34 , C07D211/38 , C07D211/70 , C07D211/88 , C07D265/32 , C07D295/00 , C07D295/02 , C07D295/04 , C07D295/08 , C07D295/10 , C07D295/116 , C07D295/12 , C07D295/14 , C07D295/155 , C07D295/18 , C07D295/192 , C07D403/10 , C07D405/10 , C07D407/10 , C07D413/10 , C07D405/12 , C07D409/12
-
公开(公告)号：SE7803660L
公开(公告)日：1978-10-03
申请号：SE7803660
申请日：1978-03-31
Applicant: HOECHST AG
Inventor： DURCKHEIMER W , BORMANN D , EHLERS E , SCHRINNER E , HAYMES R
IPC: A61K31/397 , A61K31/435 , A61K31/505 , A61K31/535 , A61K31/545 , A61K31/546 , A61P31/04 , B25J15/08 , C07D205/08 , C07D277/20 , C07D277/40 , C07D277/42 , C07D277/50 , C07D463/00 , C07D471/04 , C07D487/04 , C07D498/04 , C07D501/20 , C07D501/24 , C07D501/36 , C07D505/00 , C07D519/06 , C07F9/6561 , C07D501/34 , C07D487/02
Abstract: Cephem derivatives of the general formula in which the R2O group is in the syn-position, a process for their manufacture and pharmaceutical formulations which are active against bacterial infections and contain these compounds.
-
Patent Agency Ranking
公开(公告)号：SE7802175L
公开(公告)日：1978-02-27
申请号：SE7802175
申请日：1978-02-27
Applicant: HOECHST AG
Inventor： BORMANN D , MERKEL W , MUSCHAWECK R , MANIA D
IPC: C07D207/04 , A61K20060101 , A61K31/125 , A61K31/18 , A61K31/33 , A61K31/395 , A61K31/397 , A61K31/40 , A61K31/4015 , A61K31/402 , A61K31/403 , A61K31/4035 , A61K31/445 , A61K31/45 , A61K31/635 , A61P7/10 , C07C20060101 , C07D20060101 , C07D205/04 , C07D205/10 , C07D207/02 , C07D207/06 , C07D207/08 , C07D207/10 , C07D207/18 , C07D207/20 , C07D207/32 , C07D207/327 , C07D207/40 , C07D207/404 , C07D207/44 , C07D207/452 , C07D209/00 , C07D209/44 , C07D209/48 , C07D209/52 , C07D209/94 , C07D211/04 , C07D211/14 , C07D211/18 , C07D211/30 , C07D211/32 , C07D211/34 , C07D211/38 , C07D211/70 , C07D211/88 , C07D265/32 , C07D265/33 , C07D295/00 , C07D295/02 , C07D295/04 , C07D295/08 , C07D295/10 , C07D295/116 , C07D295/12 , C07D295/14 , C07D295/155 , C07D295/18 , C07D295/192 , C07D317/00 , C07D403/10 , C07D405/10 , C07D407/10 , C07D413/10
Abstract: 1504505 Sulphonamides HOECHST AG 25 April 1975 [25 April 1974 27 Dec 1974] 17337/75 Heading C2C The invention comprises novel compounds (I) (including salts thereof) in which R 1 and R 2 , which may be identical or different, each represents a hydrogen atom or an alkyl group having from 1 to 4 carbon atoms, and, if R 1 represents a hydrogen atom, R 2 may also represent an alkoxymethyl group having from 1 to 4 carbon atoms in the alkoxy radical, a phenoxymethyl group or a phenylthiomethyl group, R 3 represents a hydrogen atom, a straight or branched chain alkyl group having from 1 to 4 carbon atoms, a cycloalkyl group, having 5 or 6 ring members, one of which may be replaced by an oxygen or sulphur atom, a phenyl or benzyl group which may be substituted in the phenyl nucleus by one or more substituents selected from nitro groups, alkyl groups having from 1 to 3 carbon atoms, alkoxy groups having from 1 to 5 carbon atoms and halogen atoms, or represents a benzhydryl group or an alkanoyloxymethyl group having 2 to 4 carbon atoms in the alkanoyl part, X represents a halogen atom, a CF 3 or CCl 3 group, a straight or branched chain, saturated or unsaturated alkyl group having from 1 to 6 carbon atoms, a benzyl group which may be substituted in the phenyl nucleus by one or more substituents selected from halogen atoms, hydroxy and amino groups, and alkyl and alkoxy groups, or represents one of the groups -O-R 4 , -S-R 4 , SO-R 4 , SO 2 -R 4 and NR 4 R 5 , in which R 4 represents a phenyl group which may be substituted by one or more substituents selected from halogen atoms, CF 3 , OH and amino groups, alkyl and alkoxy groups having from 1 to 4 carbon atoms, and SO 2 NH 2 groups, or represents a straight or branched chain alkyl group having from 1 to 4 carbon atoms which may be substituted by a phenyl, pyridyl, furyl or thienyl group, and R 5 represents a hydrogen atom, a straight or branched chain alkyl group having from 1 to 4 carbon atoms, and the group NR 4 R 5 may represent a saturated, heterocyclic, 5- or 6-membered ring which may be interrupted by an O-, N- or S- atom, A represents a single bond, or an alkylene chain of 1 to 3 carbon atoms which may be unsaturated, interrupted by O-, N- or S-atoms or substituted by halogen atoms and/or substituted by alkyl, aralkyl, aryl groups or by mono-nuclear hetero-aromatic rings, or A represents an ortho-phenylene radical or the grouping in which Y represents a single bond or an alkylene group having from 1 to 4 carbon atoms, and R 6 and R 7 , which may be identical or different, each represents a hydrogen or halogen atom or an alkyl group having from 1 to 4 carbon atoms. They are made by standard methods. Pharmaceutical preparations having diuretic and saluretic action contain (I) as active ingredient. Administration is enterally or parenterally.
-
公开(公告)号：SE7604940L
公开(公告)日：1976-10-30
申请号：SE7604940
申请日：1976-04-29
Applicant: HOECHST AG
IPC: C07D295/14 , C07C67/00 , C07C301/00 , C07C303/40 , C07C311/39 , C07C313/00 , C07C315/00 , C07C315/04 , C07C317/48 , C07C319/14 , C07C323/67 , C07D207/09 , C07D213/71 , C07D295/155 , C07D307/52 , C07D333/34 , C07C143/80
-
公开(公告)号：SE7504841L
公开(公告)日：1975-10-27
申请号：SE7504841
申请日：1975-04-25
Applicant: HOECHST AG
Inventor： BORMANN D , MERKEL W , MUSCHAWECK R , MANIA D
IPC: C07D207/04 , A61K20060101 , A61K31/125 , A61K31/18 , A61K31/33 , A61K31/395 , A61K31/40 , A61K31/402 , A61K31/445 , A61K31/45 , A61K31/635 , A61P7/10 , C07C20060101 , C07D20060101 , C07D205/04 , C07D207/02 , C07D207/06 , C07D207/08 , C07D207/10 , C07D207/18 , C07D207/20 , C07D207/32 , C07D207/327 , C07D207/40 , C07D207/404 , C07D207/44 , C07D209/00 , C07D209/44 , C07D209/48 , C07D209/52 , C07D209/94 , C07D211/04 , C07D211/14 , C07D211/18 , C07D211/30 , C07D211/32 , C07D211/34 , C07D211/38 , C07D211/70 , C07D211/88 , C07D265/32 , C07D295/00 , C07D295/02 , C07D295/04 , C07D295/08 , C07D295/10 , C07D295/116 , C07D295/12 , C07D295/14 , C07D295/155 , C07D295/18 , C07D295/192 , C07D403/10 , C07D405/10 , C07D407/10 , C07D413/10 , C07D405/12 , C07D409/12
-
公开(公告)号：DK179875A
公开(公告)日：1975-10-26
申请号：DK179875
申请日：1975-04-24
Applicant: HOECHST AG
Inventor： BORMANN D , MERKEL W , MUSCHAWECK R , MANIA D
IPC: C07D207/04 , A61K20060101 , A61K31/125 , A61K31/18 , A61K31/33 , A61K31/395 , A61K31/40 , A61K31/402 , A61K31/445 , A61K31/45 , A61K31/635 , A61P7/10 , C07C20060101 , C07D20060101 , C07D205/04 , C07D207/02 , C07D207/06 , C07D207/08 , C07D207/10 , C07D207/18 , C07D207/20 , C07D207/32 , C07D207/327 , C07D207/40 , C07D207/404 , C07D207/44 , C07D209/00 , C07D209/44 , C07D209/48 , C07D209/52 , C07D209/94 , C07D211/04 , C07D211/14 , C07D211/18 , C07D211/30 , C07D211/32 , C07D211/34 , C07D211/38 , C07D211/70 , C07D211/88 , C07D265/32 , C07D295/00 , C07D295/02 , C07D295/04 , C07D295/08 , C07D295/10 , C07D295/116 , C07D295/12 , C07D295/14 , C07D295/155 , C07D295/18 , C07D295/192 , C07D403/10 , C07D405/10 , C07D407/10 , C07D413/10 , C07D
-
公开(公告)号：FI343374A
公开(公告)日：1975-05-30
申请号：FI343374
申请日：1974-11-27
Applicant: HOECHST AG
Inventor： BORMANN D , KNABE B , SCHRINNER E , WORM M
IPC: A61K20060101 , A61K31/43 , A61K31/545 , C01D20060101 , C07D20060101 , C07D501/04 , C07D501/06 , C07D501/20 , C07D501/24 , C07D501/36 , C07D501/40 , C07D501/42 , C07D501/46 , C07D501/48 , C07D501/56 , C07D501/60 , C07D519/00 , C07D521/00 , C07D
-
-
-
-
-
-
-
-
-
Search Results
109
records
(took 0.022 seconds)
