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    74.
    发明专利
    未知

    公开(公告)号：DK107978A

    公开(公告)日：1978-09-13

    申请号：DK107978

    申请日：1978-03-10

    Applicant: HOECHST AG

    Inventor： BORMANN D ,  KNABE B ,  SCHRINNER E ,  WORM M

    IPC: A61K31/44 ,  A61K31/535 ,  A61K31/545 ,  A61K31/546 ,  A61P31/04 ,  C07D277/20 ,  C07D277/38 ,  C07D277/40 ,  C07D463/00 ,  C07D501/20 ,  C07D505/00 ,  C07D

    Abstract: Cephem derivatives of the formula in which R1 denotes hydrogen or low-molecular alkoxy, R2 denotes hydrogen, optionally substituted alkyl, phthalide or a cation, X denotes sulfur, oxygen or CH2 and A denotes hydrogen, alkoxy, halogen or a group -CH2Y, in which Y represents hydrogen, acyloxy, alkoxy, optionally substituted carbamoyloxy or a group -SR3, in which R3 can represent acyl, alkyl or an optionally substituted 5-membered or 6-membered heterocyclic structure are disclosed as valuable antibiotics which are well suited for combating Gram-positive and in particular Gram-negative infections and also have an unexpectedly good action against penicillinase-forming staphylococci.

    76.
    发明专利
    未知

    公开(公告)号：DK567375A

    公开(公告)日：1976-06-14

    申请号：DK567375

    申请日：1975-12-12

    Applicant: HOECHST AG

    Inventor： SCHORR M ,  SCHRINNER E ,  SCHMITT W

    IPC: C07D499/66 ,  C07D499/00 ,  C07D499/64 ,  C07D499/68 ,  C07D499/70 ,  C07D

    Abstract: Acylaminopenicillanic acids of the general formula in which R1, R2 and R3 represent hydrogen or lower alkyl which may be substituted, and in which the radicals R1 and R2 or R2 and R3 may form together an alkylene radical which may be substituted, R4 and R5 represent hydrogen or lower alkyl, R6 represents phenyl which may be substituted, a monocyclic aromatic heterocycle which may be substituted, or dihydrophenyl, A represents a benzene or thiophene ring which may be substituted, and X represents oxygen or a single bond, a process for preparing them and pharmaceutical compositions active against bacterial infections containing these compounds.

    77.
    发明专利
    未知

    公开(公告)号：DK548075A

    公开(公告)日：1976-06-06

    申请号：DK548075

    申请日：1975-12-04

    Applicant: HOECHST AG

    Inventor： SCHORR M ,  SCHRINNER E ,  SCHMITT W

    IPC: C07D499/00 ,  C07D499/46 ,  C07D499/64 ,  C07D

    Abstract: Acylaminopenicillanic acids of the general formula in which A represents phenyl which may be substituted, an aromatic monocyclic heterocycle which may be substituted or dihydrophenyl, and X represents one of the groups -SO2-, -CO-, -P(R)- or -P(O)(R)- in which R represents low molecular weight alkyl, alkenyl, alkoxy, aralkyl, aralkoxy, aryl or aryloxy which may be substituted, non-toxic salts of these compounds and pharmaceutical compositions containing these compounds.

    78.
    发明专利
    未知

    公开(公告)号：BR7409595A

    公开(公告)日：1976-05-25

    申请号：BR959574

    申请日：1974-11-14

    Applicant: HOECHST AG

    Inventor： DIERY H ,  SCHNEIDER G ,  SCHRINNER E ,  GUENTHER K

    IPC: C07C67/00 ,  C07C209/00 ,  C07C209/60 ,  C07C211/14 ,  C11D1/88 ,  C11D3/48

    Abstract: 1484918 Detergent compositions HOECHST AG 15 Nov 1974 [16 Nov 1973] 49538/74 Heading C5D [Also in Division C2] Anionio cationic and/or non-ionic detergent compositions contain as an anti-microbial agent a compound of formula in which one or two of the radicals R 1 to R 7 represent a C 8-18 alkyl or alkenyl radical, one or two of the radicals R 2 -R 6 represent a radical of formula wherein Y is a hydrogen or alkali metal atom, each of the remaining radicals R 1 to R 7 represent a hydrogen atom or a methyl group, n is 2 or 3 and o and p are zero or 1. The compositions may also contain optical brightening agents, perborates, enzymes, perfumes, fluorescence agents, foam-producing and foam-depressing agents, and deposit-preventing auxiliaries. Examples disclose compositions containing antimicrobial compounds as above together with (3) the sodium salt of a secondary alkane sulphonic acid (or the sodium salt of dodecylbenzene sulphonic acid or a mixture of the former with the sodium salt of a C 15-18 olefin sulphonate), oxyethylated tallow fatty alcohol, sodium soap, sodium tripolyphosphate, sodium metasilicate, magnesium silicate, carboxymethyl cellulose, optical brightener, perfume oil and sodium perborate, (4) oxyethylated coco fatty acid, oxyethylated isotridecyl alcohol, sodium tripolyphosphate, sodium silicate, calcined sodium carbonate, carboxymethyl cellulose and sodium sulphate, (5) distearyl-dimethylammonium chloride, oxyethylated oleyl alcohol, an optical brightener and perfume oil, (6) oxyethylated coco fatty alcohol, perfume and dyestuffs, (7) oxyethylated coco fatty alcohol, sodium tripolyphosphate, sodium silicate, calcined sodium carbonate, carboxymethyl cellulose and sodium sulphate.

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