-
公开(公告)号:FI781754A
公开(公告)日:1978-12-04
申请号:FI781754
申请日:1978-06-01
Applicant: HOFFMANN LA ROCHE
Inventor: MONTAVON MARC , REINER ROLAND
IPC: A61K20060101 , A61K31/54 , A61K31/545 , A61K31/546 , A61P31/04 , C07B20060101 , C07D20060101 , C07D279/08 , C07D499/00 , C07D501/04 , C07D501/20 , C07D501/36 , C07D501/40 , C07D501/46 , C07D
-
公开(公告)号:FI751815A
公开(公告)日:1975-12-22
申请号:FI751815
申请日:1975-06-18
Applicant: HOFFMANN LA ROCHE
Inventor: MONTAVON MARC , REINER ROLAND
IPC: C07D501/20 , A61K31/545 , A61K31/546 , A61P31/04 , C07D239/54 , C07D239/553 , C07D239/56 , C07D253/075 , C07D501/04 , C07D501/06 , C07D501/36 , C07D501/57 , C07D
-
公开(公告)号:AU4949272A
公开(公告)日:1974-05-30
申请号:AU4949272
申请日:1972-11-30
Applicant: HOFFMANN LA ROCHE
Inventor: LANZ PAUL , REINER ROLAND , VOGLER KARL
IPC: C07D499/00 , C07D499/60 , C07D501/20 , C07D501/28 , C07D99/16 , C07D99/24
-
公开(公告)号:SI8012952A8
公开(公告)日:1997-06-30
申请号:SI8012952
申请日:1980-11-20
Applicant: HOFFMANN LA ROCHE
Inventor: MONTAVON MARCO , REINER ROLAND
IPC: C07D501/00 , A61K31/545 , A61K31/546 , A61P31/04 , C07C20060101 , C07D20060101 , C07D501/04 , C07D501/16 , C07D501/36 , C07D501/46
Abstract: For the Contracting States : BE, CH, DE, FR, GB, IT, LI, LU, NL, SE 1. A process for the manufacture of acyl derivatives of general formula I see diagramm : EP0030294,P12,F1 in which R represents hydrogen or a readily hydrolyzable ester group, as well as of salts of these compounds and hydrates of these compounds or of their salts by reating a halide of general formula II see diagramm : EP0030294,P12,F2 in which R has the significance given above and Y represents a halogen atom, or a salt of this compound with thiourea and, if desired, converting a compound of formula I obtained into a salt or hydrate or into a hydrate of this salt, characterized in that X signifies one of the groups see diagramm : EP0030294,P13,F3 in which R' represents hydrogen or a readily hydrolysable ether group.
-
公开(公告)号:LV5519A3
公开(公告)日:1994-03-10
申请号:LV930506
申请日:1993-06-08
Applicant: HOFFMANN LA ROCHE
Inventor: MONTAVON MARC , REINER ROLAND
IPC: A61K31/545 , C07D501/36
-
公开(公告)号:NO166229C
公开(公告)日:1991-06-19
申请号:NO803516
申请日:1980-11-20
Applicant: HOFFMANN LA ROCHE
Inventor: MONTAVON MARC , REINER ROLAND
IPC: C07D501/00 , A61K31/545 , A61K31/546 , A61P31/04 , C07C20060101 , C07D20060101 , C07D501/04 , C07D501/16 , C07D501/36 , C07D501/46
Abstract: For the Contracting States : BE, CH, DE, FR, GB, IT, LI, LU, NL, SE 1. A process for the manufacture of acyl derivatives of general formula I see diagramm : EP0030294,P12,F1 in which R represents hydrogen or a readily hydrolyzable ester group, as well as of salts of these compounds and hydrates of these compounds or of their salts by reating a halide of general formula II see diagramm : EP0030294,P12,F2 in which R has the significance given above and Y represents a halogen atom, or a salt of this compound with thiourea and, if desired, converting a compound of formula I obtained into a salt or hydrate or into a hydrate of this salt, characterized in that X signifies one of the groups see diagramm : EP0030294,P13,F3 in which R' represents hydrogen or a readily hydrolysable ether group.
-
公开(公告)号:NO166228B
公开(公告)日:1991-03-11
申请号:NO812083
申请日:1981-06-18
Applicant: HOFFMANN LA ROCHE
Inventor: MONTAVON MARC , REINER ROLAND
IPC: C07D501/00 , A61K31/545 , A61K31/546 , A61P31/04 , C07C20060101 , C07D20060101 , C07D501/04 , C07D501/16 , C07D501/36 , C07D501/46
Abstract: For the Contracting States : BE, CH, DE, FR, GB, IT, LI, LU, NL, SE 1. A process for the manufacture of acyl derivatives of general formula I see diagramm : EP0030294,P12,F1 in which R represents hydrogen or a readily hydrolyzable ester group, as well as of salts of these compounds and hydrates of these compounds or of their salts by reating a halide of general formula II see diagramm : EP0030294,P12,F2 in which R has the significance given above and Y represents a halogen atom, or a salt of this compound with thiourea and, if desired, converting a compound of formula I obtained into a salt or hydrate or into a hydrate of this salt, characterized in that X signifies one of the groups see diagramm : EP0030294,P13,F3 in which R' represents hydrogen or a readily hydrolysable ether group.
-
公开(公告)号:NO160301C
公开(公告)日:1989-04-05
申请号:NO865360
申请日:1986-12-30
Applicant: HOFFMANN LA ROCHE
Inventor: MONTAVON MARC , REINER ROLAND
IPC: C07D501/00 , C07D501/36
-
公开(公告)号:NO159797C
公开(公告)日:1989-02-08
申请号:NO791776
申请日:1979-05-29
Applicant: HOFFMANN LA ROCHE
Inventor: MONTAVON MARC , REINER ROLAND
IPC: C07D501/04 , A61K20060101 , A61K31/545 , A61K31/546 , A61P31/04 , C07C20060101 , C07D20060101 , C07D501/00 , C07D501/16 , C07D501/22 , C07D501/36 , C07D501/46 , C07D501/56 , C07D501/60
-
公开(公告)号:NO159797B
公开(公告)日:1988-10-31
申请号:NO791776
申请日:1979-05-29
Applicant: HOFFMANN LA ROCHE
Inventor: MONTAVON MARC , REINER ROLAND
IPC: C07D501/04 , A61K20060101 , A61K31/545 , A61K31/546 , A61P31/04 , C07C20060101 , C07D20060101 , C07D501/00 , C07D501/16 , C07D501/22 , C07D501/36 , C07D501/46 , C07D501/56 , C07D501/60
-
-
-
-
-
-
-
-
-