公开(公告)号：US3917815A

公开(公告)日：1975-11-04

申请号：US45844474

申请日：1974-04-05

Applicant: OREAL

Inventor： KALOPISSIS GREGOIRE ,  BOUILLON CLAUDE

IPC: A61K8/49 ,  A61K31/44 ,  A61Q5/02 ,  A61Q15/00 ,  C07D213/89 ,  A61K7/06 ,  A61K7/36 ,  A61K7/38

CPC classification number: A61K31/44 ,  A61K8/4933 ,  A61K2800/58 ,  A61Q5/006 ,  A61Q5/008 ,  A61Q5/02 ,  A61Q5/04 ,  A61Q5/06 ,  A61Q15/00 ,  A61Q17/005 ,  C07D213/89 ,  Y10S424/01 ,  Y10S424/02 ,  Y10S424/04 ,  Y10S424/05

Abstract: WHEREIN N IS EQUAL TO 0 OR 1, THE SULFUR ATOM BEING ATTACHED TO THE N-oxypyridyl nucleus in a position ortho or para to the NO group, and R1 represents hydrogen, -COR2 or -SO2R2 wherein R2 is alkyl having 1-4 carbon atoms, phenyl or tolyl; B. THE METAL COMPLEX OF THE COMPOUND IN (A) WHEN R1 is hydrogen; and C. THE METAL SALT OF THE COMPOUND IN (A) WHEN R1 is -COR2 or SO2R2. These derivatives are usefully employed in compositions for application to the hair, scalp or skin in order to combat the greasy and unaesthetic appearance of the hair and scalp and to counteract the formation of body odours of skin. The composition includes the said derivative of pyridine together with an appropriate carrier including, for instance, water, lower alkanol, an aqueous solution of a lower alkanol, a detergent and a cosmetic powder. The said derivative of pyridine can be included in such compositions in amounts ranging from about 0.0110 percent by weight thereof.
N-oxypyridyl derivative selected from the group consisting of A. A COMPOUND OF THE FORMULA

Abstract translation: 选自下组的N-氧基吡啶基衍生物：其中N等于0或1的化合物，在NO基团的邻位或对位处与N-氧基吡啶核连接的硫原子，以及R 1 表示氢，-COR 2或-SO 2 R 2，其中R 2是具有1-4个碳原子的烷基，苯基或甲苯基; B.化合物的金属复合物（A）当R1是氢时; 和（C）中化合物的金属盐，当R1是-COR2或-SO2R2时。

公开(公告)号：US3905761A

公开(公告)日：1975-09-16

申请号：US30199872

申请日：1972-10-30

Applicant: OREAL

Inventor： KALOPISSIS GREGOIRE ,  BUGAUT ANDREE ,  ESTRADIER FRANCOISE

IPC: A61K8/41 ,  A61Q5/10 ,  A61K7/13

CPC classification number: A61Q5/10 ,  A61K8/413 ,  Y10S424/02

Abstract: Diphenylamines having the formula

WHEREIN: Y represents a member selected from the group consisting of a hydroxy and amino, R1 and R3, each independently, represent a member selected from the group consisting of hydrogen, halogen, lower alkyl, lower alkoxy, a ureido residue, and -NHCOR wherein R is lower alkyl, R2 represents a member selected from the group consisting of hydrogen, halogen, lower alkyl, lower alkoxy, a ureido residue, -NHCOR wherein R is lower alkyl, and -NHR8 wherein R8 represents a member selected from the group consisting of hydrogen, lower alkyl, lower hydroxyalkyl and carbamylmethyl, with the proviso that when R2 is -NHR8, R3 is not hydrogen R4, R5, R6, and R7 each independently represent a member selected from the group consisting of hydrogen, halogen, lower alkyl and lower alkoxy, with the proviso that when Y is hydroxy, R2 is not hydrogen, halogen, lower alkyl or lower alkoxy, and that when Y is amino, at least two of R1, R2 and R3 are other than a hydrogen and R2 is not hydrogen when R4, R5, R6 and R7 are all hydrogen and the acid addition salts of said diphenylamines.

Abstract translation: 具有式WHEREIN：Y的二苯胺表示选自羟基和氨基的成员，R 1和R 3各自独立地表示选自氢，卤素，低级烷基，低级烷氧基，脲基残基的成员 和-NHCOR，其中R是低级烷基，R 2表示选自氢，卤素，低级烷基，低级烷氧基，脲基残基，-NHCOR，其中R是低级烷基，-NHR 8，其中R8代表成员 选自氢，低级烷基，低级羟基烷基和氨基甲酰甲基，条件是当R 2为-NHR 8时，R 3不为氢，R 4，R 6和R 7各自独立地表示选自氢， ，卤素，低级烷基和低级烷氧基，条件是当Y为羟基时，R 2不为氢，卤素，低级烷基或低级烷氧基，当Y为氨基时，R 1，R 2和R 3中的至少两个为 氢和 当R4，R5，R6和R7都是氢时，R2不是氢，也就是所说的二苯胺的酸加成盐。

公开(公告)号：US3882114A

公开(公告)日：1975-05-06

申请号：US24490672

申请日：1972-04-17

Applicant: OREAL

Inventor： KALOPISSIS GREGOIRE ,  ABEGG JEAN-LOUIS ,  GHILARDI GUILIANA ,  DE BEAULIEU HENRI PHILIPPE

IPC: A61K8/49 ,  A61Q5/04 ,  A61Q5/06 ,  C07D295/13 ,  C07D87/42 ,  C07D87/46

CPC classification number: C07D295/13 ,  A61K8/49 ,  A61Q5/04 ,  A61Q5/06

Abstract: -C12H25 and -C18H37 and an acid catalyst in an amount effective to polymerize the compound on the hair and then drying the hair.

-CH2-CH2HS, -CH2COOH,

-CH2-CH2-S-S-CH2-CH2-NHCONH2,

R3 and R''3 are hydrogen or taken together form the divalent radical -CH2-CH2-, Y is hydrogen,

WHEREIN X is O or S; R1 and R2 are ethyl or together form the divalent radical -CH2-CH2-O-CH2-CH2-, -CH2-CH2-CH2-CH2-CH2- or

Polycondensable compound and a process for treating hair employing a composition containing said polycondensable compound having the formula

Abstract translation: 可缩聚化合物和使用含有式WHEREIN X的所述可缩聚化合物的组合物处理毛发的方法为O或S; R 1和R 2是乙基或一起形成二价基团-CH 2 -CH 2 -O-CH 2 -CH 2 - ， - CH 2 -CH 2 -CH 2 -CH 2 - 或R 3和R'3是氢或一起形成二价基团 -CH 2 -CH 2 - ，Y是氢，-CH 2 -CH 2 -S-CH 2 -CH 2 -NHCONH 2，-CH 2 -CH 2 HS，-CH 2 COOH，-C 12 H 25和-C 18 H 37，以及有效使聚合化合物的酸催化剂 头发然后干燥头发。

公开(公告)号：US3876368A

公开(公告)日：1975-04-08

申请号：US38761373

申请日：1973-08-13

Applicant: OREAL

Inventor： KALOPISSIS GREGOIRE ,  BUGAUT ANDREE ,  ESTRADIER FRANCOISE

IPC: A61K8/41 ,  A61Q5/10 ,  H01K1/12 ,  D06P3/04

CPC classification number: A61K8/413 ,  A61Q5/10 ,  Y10S424/01 ,  Y10S424/02

Abstract: Imdamine having the formula

Wherein R and R'' each independently represent a member selected from the group consisting of hydrogen, lower alkyl having 1-4 carbon atoms, lower alkoxy having 1-4 carbon atoms, amino, acylamino wherein the acyl moiety has 1 to 4 carbon atoms and hydroxy, with the proviso that one, but not both of R and R'' is said amino, acylamino or hydroxy; R.sub.1 and R.sub.2 each independently represent a member selected from the group consisting of lower alkyl having 1-4 carbon atoms and lower alkyl having 1-4 carbon atoms and substituted with a member selected from the group consisting of hydroxy, acylamino wherein the acyl moiety has 1 to 4 carbon atoms, carbamyl, piperidino, benzoylamino and alkylsulfonamido wherein the alkyl moiety has 1 to 4 carbon atoms; R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7 and R.sub.8 each independently represent a member selected from the group consisting of hydrogen, lower alkyl having 1-4 carbon atoms and lower alkoxy having 1-4 carbon atoms, and the salts formed by these indamines with organic or inorganic acids, in particular, their acetates, hydrochlorides, hydrobromides, persulfates, perchlorates and the double zinc salts of these compounds, which can, of course, be in a tautomeric form of that represented by formula (I), are usefully employed for dyeing keratinous fibers, and, in particular, human hair.

公开(公告)号：US3862221A

公开(公告)日：1975-01-21

申请号：US28407672

申请日：1972-08-28

Applicant: OREAL

Inventor： KALOPISSIS GREGOIRE ,  ABEGG JEAN-LOUIS ,  GHILARDI GUILIANA ,  DE BEAULIEU HENRI PHILIPPE

IPC: A61K8/46 ,  A61Q5/00 ,  C07C323/44 ,  C07C127/00

CPC classification number: C07C323/44 ,  A61K8/46 ,  A61Q5/04

Abstract: Cosmetic composition comprising, in a suitable carrier, at least one active compound including both at least one disulfide function and at least one group responding to the formula:

IN WHICH: R is selected from the group consisting of hydrogen, a lower alkyl, a hydroxy-methyl or an alkoxy methyl radical; R'' is selected from the group consisting of hydrogen, and a lower alkyl radical; THE NITROGEN ATOM IN SAID GROUP BEING ATTACHED TO A REMAINDER WHICH IS SUFFICIENTLY ELECTROPHILE TO PREVENT THE IMMEDIATE RELEASE OF FORMOL.

Abstract translation: 在合适的载体中包含至少一种包含至少一个二硫键功能的活性化合物和至少一个响应式的基团的化妆品组合物：

公开(公告)号：US3691270A

公开(公告)日：1972-09-12

申请号：US3691270D

申请日：1970-02-04

Applicant: OREAL

Inventor： CHARLE ROGER ,  ZVIAK CHARLES ,  KALOPISSIS GREGOIRE

IPC: A61K8/02 ,  A61K8/11 ,  A61Q1/14 ,  A61Q5/10 ,  A61Q17/04 ,  A61K7/02

CPC classification number: A61Q17/04 ,  A61K8/0208 ,  A61K8/11 ,  A61K2800/412 ,  A61Q1/14 ,  A61Q5/10 ,  Y10T428/2984 ,  Y10T428/2987

Abstract: A cosmetic makeup base foundation cream composition for the skin comprises an alveolar polymeric support containing a multiplicity of rupturable microcapsules containing said makeup base foundation cream.

公开(公告)号：US3676546A

公开(公告)日：1972-07-11

申请号：US3676546D

申请日：1969-07-24

Applicant: OREAL

Inventor： GHILARDI GUILIANNA ,  KALOPISSIS GREGOIRE ,  BEAULIEU HENRY PHILIPPE DE ,  ABEGG JEAN-LOUIS

IPC: A45D7/04 ,  A61K7/10

CPC classification number: A61Q5/04 ,  A45D7/04 ,  A61K8/84 ,  A61K2800/95

Abstract: A neutralizing composition to effect the second stage of neutralization of a permanent wave operation on the hair is an aqueous solution containing an N-methylol compound as an active compound in amounts of 0.5-12 percent by weight of the composition. An oxidizing agent can also be included in the composition in amounts such that the concentration of active compound and oxidizing agent is less than 1.7 moles/liter.

Abstract translation: 实现中和毛发上的永久性挥发的第二阶段的中和组合物是含有组合物重量的0.5-12％的N-羟甲基化合物作为活性化合物的水溶液。 氧化剂也可以以使得活性化合物和氧化剂的浓度小于1.7摩尔/升的量包含在组合物中。

公开(公告)号：US3674902A

公开(公告)日：1972-07-04

申请号：US3674902D

申请日：1968-09-27

Applicant: OREAL

Inventor： KALOPISSIS GREGOIRE ,  VANLERBERGHE GUY

IPC: C07C41/00 ,  C07C41/01 ,  C07C43/00 ,  C07C43/02 ,  C07C43/14 ,  C07C43/16 ,  C08G65/28 ,  C11D1/00 ,  F16B35/00 ,  A61K7/06 ,  A61K7/12

CPC classification number: A61K8/39 ,  A61Q19/00 ,  C07C43/14 ,  F16B35/00 ,  Y10S424/01

Abstract: Cosmetic compositions, such as shampoos and hair dyes, which contain non-ionic surface active agents that form cleaning compositions that do not irritate the mucous membrane of the eyes having the formula IN WHICH R is selected from the group consisting of alkyl, alkenyl and alkyl and alkenyls having intervening CONH, O and CHOH groups having eight to 22 carbon atoms, and n is 1 to 5 and methods of making said compound.

公开(公告)号：US3671643A

公开(公告)日：1972-06-20

申请号：US3671643D

申请日：1969-09-15

Applicant: OREAL

Inventor： KALOPISSIS GREGOIRE

IPC: A61K8/44 ,  A61K8/46 ,  A61Q5/00 ,  A61Q19/00 ,  A61K27/00

CPC classification number: A61K8/46 ,  A61K8/447 ,  A61Q5/00 ,  A61Q5/008 ,  A61Q19/00 ,  A61Q19/008

Abstract: A process of treating acne with a composition containing substituted cysteamine compounds.

Abstract translation: 用含有取代的半胱胺化合物的组合物治疗痤疮的方法。

公开(公告)号：US3649158A

公开(公告)日：1972-03-14

申请号：US3649158D

申请日：1968-08-05

Applicant: OREAL

Inventor： KALOPISSIS GREGOIRE ,  BUGAUT ANDREE

IPC: A61K8/49 ,  A61Q5/06 ,  C09B50/00 ,  D06P1/42 ,  D06P3/02 ,  D06P3/04 ,  D06P3/08 ,  D06P3/14

CPC classification number: A61K8/494 ,  A61Q5/065 ,  Y10S8/917

Abstract: A process and composition for dyeing keratinic fibers, particularly, human hair, in which tetrazolium salts are applied to the fibers in a colorless oxidized state and reduced to colored insoluble formazanes by reducing agents. The reducing agents are used so that the keratinic bonds are not disrupted and can be used at the same time that a permanent wave process is applied. Also, various shades can be obtained using leuco derivative dyes which become oxidized when functioning as reducing agents.

Abstract translation: 用于染色角蛋白纤维，特别是人毛的方法和组合物，其中将四唑鎓盐以无色氧化态施用于纤维，并通过还原剂还原成为不溶性的甲。。 使用还原剂，使得角蛋白键不被破坏，并且可以在施加永久性波过程的同时使用。 此外，可以使用当用作还原剂时被氧化的无色衍生物染料获得各种色调。