公开(公告)号：US09915619B2

公开(公告)日：2018-03-13

申请号：US15388010

申请日：2016-12-22

Applicant: ARIEL ROSENBERG

Inventor： Adir Mugrabi ,  Ariel Rosenberg

IPC: G01N21/00 ,  G01N21/87 ,  G01N21/01

CPC classification number: G01N21/87 ,  G01N21/01 ,  G01N2201/025

Abstract: A portable small-object holding device, comprising: a housing, movable gripper jaws configured to grip and hold a small object; at least one hinge and at least one cog-wheel configured to enable rotating said at least one hinge around its longitudinal axis; and wherein the portable small-object holding device is adapted to enable illuminating the small object when being held within said portable small-object holding device, by a beam of light at least one wavelength. The inspection of the small-object is carried out after inserting the portable small-object holding device via an aperture comprised in a portable apparatus for inspecting small objects, and preferably engaging the portable small-object holding device with the portable apparatus for inspecting small objects.

公开(公告)号：US09874511B2

公开(公告)日：2018-01-23

申请号：US14669801

申请日：2015-03-26

Applicant: Sysmex Corporation

Inventor： Toshikatsu Fukuju ,  Yusuke Matsumoto

IPC: G01N35/02 ,  G01N21/13 ,  G01N21/75 ,  G01N21/64 ,  G01N35/00 ,  G01N35/04 ,  G01N35/10

CPC classification number: G01N21/13 ,  G01N21/6428 ,  G01N21/75 ,  G01N35/0098 ,  G01N35/025 ,  G01N35/04 ,  G01N2021/135 ,  G01N2035/0406 ,  G01N2035/041 ,  G01N2035/103 ,  G01N2201/022 ,  G01N2201/025

Abstract: An analyzer including a housing with a mutually adjacent first side and a second side, and an annular reagent holding part disposed within the housing is disclosed. An immunoassay method for measuring antigen or antibody of a measurement object contained in a sample and performed by the analyzer is also disclosed.

公开(公告)号：US09869612B2

公开(公告)日：2018-01-16

申请号：US14695108

申请日：2015-04-24

Applicant: OLYMPUS CORPORATION

Inventor： Nobuhiko Morimoto

IPC: B32B43/00 ,  G01N1/04 ,  G01N1/08 ,  G02B21/36 ,  G01N1/31 ,  G01N21/64 ,  B32B41/00

CPC classification number: G01N1/04 ,  B32B41/00 ,  B32B43/006 ,  B32B2310/0831 ,  G01N1/08 ,  G01N1/312 ,  G01N21/6456 ,  G01N2201/025 ,  G02B21/365 ,  Y10T156/1158 ,  Y10T156/1179 ,  Y10T156/19 ,  Y10T156/1917 ,  Y10T156/1983

Abstract: The present invention provides a substrate collecting device that includes a first stage on which a sheet is placed with a plurality of substrates facing downward, an sampler which carries out a predetermined operation on some of the substrates, which are disposed at predetermined positions, from above the first stage thereby to cause the substrates to come off from the sheet and fall, an optical system and a collector disposed below the first stage, and a second stage, which integrally moves the optical system and the collector in a horizontal direction. The second stage is capable of positioning the optical system and the collector at two positions at which the optical system or the collector is disposed substantially vertically below a predetermined position.

公开(公告)号：US09816916B2

公开(公告)日：2017-11-14

申请号：US14425259

申请日：2013-09-03

Applicant: Johann Wolfgang Goethe-Universitaet

Inventor： Francesco Pampaloni ,  Ernst H. K. Stelzer ,  Christian Mattheyer

IPC: G01N1/00 ,  G01N21/03 ,  B01L3/00 ,  G01N21/11 ,  G01N21/64 ,  G01N21/13 ,  G02B21/16 ,  G02B21/00 ,  G02B21/26 ,  G02B21/33

CPC classification number: G01N21/03 ,  B01L3/5082 ,  B01L2300/042 ,  B01L2300/0858 ,  G01N21/0303 ,  G01N21/11 ,  G01N21/13 ,  G01N21/6458 ,  G01N21/6486 ,  G01N2021/0307 ,  G01N2021/0346 ,  G01N2021/0378 ,  G01N2021/0389 ,  G01N2201/025 ,  G01N2201/06113 ,  G02B21/0076 ,  G02B21/16 ,  G02B21/26 ,  G02B21/33

Abstract: A capillary cell is described along with an arrangement and a method for receiving, positioning and examining a microscopic specimen, in particular a cleared fluorescent specimen with the help of a single-plane fluorescence microscope. The capillary cell is suitable for being positioned in a chamber volume and contains a capillary section, which comprises a wall. The wall encloses a specimen volume and is planar and transparent in at least some sections. In addition, the capillary cell includes an upper and a lower closure section, which are connected to the capillary section and which seal the capillary section. The specimen volume is separated from the chamber volume by the capillary section, the upper closure section and the lower closure section.

公开(公告)号：US20170299515A1

公开(公告)日：2017-10-19

申请号：US15098598

申请日：2016-04-14

Applicant: SHIMADZU CORPORATION

Inventor： Tomoki SASAYAMA

IPC: G01N21/64 ,  G02B5/20

CPC classification number: G01N21/645 ,  G01N2021/6463 ,  G01N2201/022 ,  G01N2201/025 ,  G02B5/208 ,  G02B26/023

Abstract: An optical measuring device including a sample placement portion for a measurement sample to be placed therein; a light source portion for emitting a measurement beam toward the measurement sample that is placed in the sample placement portion; and a detector for detecting sample information from a measurement sample that is disposed in the sample placement portion; a cover portion that is able to open and close, for accessing the interior of the sample placement portion, is formed on the sample placement portion; an optical element member for not transmitting light of at least a prescribed wavelength band within the measurement beam; and a driving mechanism that is linked mechanically with the opening and closing of the cover portion to move the optical element member.

公开(公告)号：US09488519B2

公开(公告)日：2016-11-08

申请号：US14730762

申请日：2015-06-04

Applicant: SAMCO INC.

Inventor： Kiyoshi Hasegawa ,  Hiroshi Kawamura ,  Peter Wood

IPC: G01N21/55 ,  G01J1/02 ,  G01J1/42 ,  G01N21/84

CPC classification number: G01J1/0238 ,  G01J1/4257 ,  G01N21/55 ,  G01N2021/8427 ,  G01N2201/025 ,  G01N2201/1087

Abstract: The present invention provides a light beam measuring instrument that can securely receive light reflected by a sample. The light beam measuring instrument 1 includes an optical axis tilting mechanism 13 that includes a first tilting mechanism 131 and a second tilting mechanism 132. From the optical axis A1 of irradiation light beam emitted from a light beam source 112, the first tilting mechanism 131 tilts the optical axis A1 about the first tilting axis T1. The second tilting mechanism 132 tilts the optical axis A1 about the second tilting axis T2. The light beam measuring instrument 1 can receive the light reflected by the semiconductor chip C by means of operation of the optical axis tilting mechanism 13 even if the light reflected by the semiconductor chip C is tilted. Accordingly, this apparatus can securely perform measurement or inspection using the light beam.

Abstract translation: 本发明提供了一种可以安全地接收由样品反射的光的光束测量仪器。 光束测量仪1包括光轴倾斜机构13，其包括第一倾斜机构131和第二倾斜机构132.从光束源112发射的照射光束的光轴A1，第一倾斜机构131倾斜 围绕第一倾斜轴线T1的光轴A1。 第二倾斜机构132围绕第二倾斜轴T2倾斜光轴A1。 即使由半导体芯片C反射的光倾斜，光束测量仪器1也可以通过光轴倾斜机构13的操作来接收由半导体芯片C反射的光。 因此，该装置可以可靠地执行使用光束的测量或检查。

公开(公告)号：US20160238623A1

公开(公告)日：2016-08-18

申请号：US15136610

申请日：2016-04-22

Applicant: Fluidigm Corporation

Inventor： Gang Sun ,  Greg Harris ,  Andy May ,  Kyle Self ,  Kevin Farrell ,  Paul Wyatt

IPC: G01N35/00 ,  G01N21/64 ,  C12Q1/68 ,  B01L3/00 ,  G01N35/10

CPC classification number: G01N35/00029 ,  B01L3/5027 ,  B01L3/502715 ,  B01L2200/10 ,  B01L2300/06 ,  B01L2300/0654 ,  B01L2300/0829 ,  C12Q1/686 ,  G01N15/1475 ,  G01N21/6428 ,  G01N35/00732 ,  G01N35/00871 ,  G01N35/0092 ,  G01N35/0099 ,  G01N35/1065 ,  G01N2035/00148 ,  G01N2035/00237 ,  G01N2035/00752 ,  G01N2035/0091 ,  G01N2035/1034 ,  G01N2201/025 ,  G01N2201/0446 ,  Y10S901/01 ,  Y10T436/11

Abstract: A system includes a platform including one or more workstations and a microfluidic input device coupled to the one or more workstations. The microfluidic input device is adapted to receive a microfluidic device from a user. The system also includes a robotic device comprising a robotic arm and disposed on the platform. The robotic arm is capable of accessing the one or more workstations and is configured to transfer a plurality of sample solutions from a first spatial location to the microfluidic device when coupled to the microfluidic input device. The system further includes a multi-pixel image capturing device optically coupled to the microfluidic device and an image processing device operably coupled to the multi-pixel image capturing device. The multi-pixel image capturing device is adapted to capture a plurality of multi-pixel images. The image processing device is configured to receive the plurality of multi-pixel images.

Abstract translation: 系统包括包括一个或多个工作站的平台和耦合到该一个或多个工作站的微流体输入设备。 微流体输入装置适于从用户接收微流体装置。 该系统还包括机器人装置，其包括机器臂并且设置在平台上。 机器臂能够访问一个或多个工作站，并且被配置为当耦合到微流体输入装置时将多个样品溶液从第一空间位置传送到微流体装置。 该系统还包括光学耦合到微流体装置的多像素图像捕获装置和可操作地耦合到多像素图像捕获装置的图像处理装置。 多像素图像捕获装置适于捕获多个多像素图像。 图像处理装置被配置为接收多个多像素图像。

公开(公告)号：US20160061851A1

公开(公告)日：2016-03-03

申请号：US14834782

申请日：2015-08-25

Applicant: SYSMEX CORPORATION

Inventor： Nobuyoshi YAMAKAWA ,  Hiroo TATSUTANI ,  Yuichiro OHMAE

IPC: G01N35/00 ,  G01N35/02 ,  G01N35/04 ,  G01N21/78

CPC classification number: G01N35/00732 ,  G01N21/78 ,  G01N35/00 ,  G01N35/00871 ,  G01N35/02 ,  G01N35/026 ,  G01N35/04 ,  G01N2021/7759 ,  G01N2035/00326 ,  G01N2035/00831 ,  G01N2035/00851 ,  G01N2035/00881 ,  G01N2035/0465 ,  G01N2035/0491 ,  G01N2201/025 ,  G01N2201/061

Abstract: Provided is a test system operable with a simplified structure. A test system includes a test device and a test device each of which transports and tests a sample. The test device includes a master control unit, which performs assignment of samples to the test device and the test device, and control of a transport operation of the sample assigned to the test device. The test device includes a slave control unit, which controls a transport operation of the sample assigned to the test device by the master control unit.

Abstract translation: 提供了一种可以简化结构操作的测试系统。 测试系统包括测试设备和测试设备，每个测试设备都运送和测试样品。 测试装置包括主控制单元，其执行对测试设备和测试设备的采样分配，以及对分配给测试设备的样本的传输操作的控制。 测试装置包括从控制单元，其控制由主控制单元分配给测试装置的样本的传送操作。

公开(公告)号：US20150211981A1

公开(公告)日：2015-07-30

申请号：US14425259

申请日：2013-09-03

Applicant: Johann Wolfgang Goethe-Universitaet

Inventor： Francesco Pampaloni ,  Ernst H. K. Stelzer ,  Christian Mattheyer

IPC: G01N21/03 ,  G02B21/16 ,  G01N21/64 ,  G01N21/11 ,  G01N21/13

CPC classification number: G01N21/03 ,  B01L3/5082 ,  B01L2300/042 ,  B01L2300/0858 ,  G01N21/0303 ,  G01N21/11 ,  G01N21/13 ,  G01N21/6458 ,  G01N21/6486 ,  G01N2021/0307 ,  G01N2021/0346 ,  G01N2021/0378 ,  G01N2021/0389 ,  G01N2201/025 ,  G01N2201/06113 ,  G02B21/0076 ,  G02B21/16 ,  G02B21/26 ,  G02B21/33

Abstract: A capillary cell is described along with an arrangement and a method for receiving, positioning and examining a microscopic specimen, in particular a cleared fluorescent specimen with the help of a single-plane fluorescence microscope. The capillary cell is suitable for being positioned in a chamber volume and contains a capillary section, which comprises a wall. The wall encloses a specimen volume and is planar and transparent in at least some sections. In addition, the capillary cell includes an upper and a lower closure section, which are connected to the capillary section and which seal the capillary section. The specimen volume is separated from the chamber volume by the capillary section, the upper closure section and the lower closure section.

Abstract translation: 描述毛细管细胞以及借助于单平面荧光显微镜来接收，定位和检查微观样本，特别是清除的荧光样品的装置和方法。 毛细管适合于定位在腔体内，并且包含毛细管部分，其包括壁。 墙壁包围样品体积，至少在某些部分是平面和透明的。 此外，毛细管电池包括上部和下部封闭部分，其连接到毛细管部分并密封毛细管部分。 通过毛细管部分，上封闭部分和下封闭部分将试样体积与腔室体积分离。

公开(公告)号：US20150119298A1

公开(公告)日：2015-04-30

申请号：US14500399

申请日：2014-09-29

Applicant: Fluidigm Corporation

Inventor： Gang Sun ,  Greg Harris ,  Andy May ,  Kyle Self ,  Kevin Farrell ,  Paul Wyatt

IPC: G01N35/00

CPC classification number: G01N35/00029 ,  B01L3/5027 ,  B01L3/502715 ,  B01L2200/10 ,  B01L2300/06 ,  B01L2300/0654 ,  B01L2300/0829 ,  C12Q1/686 ,  G01N15/1475 ,  G01N21/6428 ,  G01N35/00732 ,  G01N35/00871 ,  G01N35/0092 ,  G01N35/0099 ,  G01N35/1065 ,  G01N2035/00148 ,  G01N2035/00237 ,  G01N2035/00752 ,  G01N2035/0091 ,  G01N2035/1034 ,  G01N2201/025 ,  G01N2201/0446 ,  Y10S901/01 ,  Y10T436/11

Abstract: A system for performing one or more microfluidic processes includes an integrated fluidic device comprising a plurality of well regions and a plurality of control valves and a workflow manager. The system also includes a transfer robot adapted to transfer the integrated fluidic device between a plurality of stations in response to a series of instructions from the workflow manager and a first station comprising a dispensing robot adapted to dispense at least one of a plurality of sample solutions and at least one of a plurality of reagents into the integrated fluidic device. The system further includes a second station comprising a fluidic controller unit and a third station comprising an inspection station.

Abstract translation: 用于执行一个或多个微流程过程的系统包括包括多个井区域和多个控制阀以及工作流程管理器的集成流体设备。 该系统还包括传送机器人，其适于响应于来自工作流程管理器的一系列指令而在多个站之间传送集成流体设备，第一站包括分配机器人，其适于分配多个样品溶液中的至少一个样品溶液 和多个试剂中的至少一种进入集成流体装置。 该系统还包括第二站，其包括流体控制器单元和包括检查站的第三站。