公开(公告)号：KR1020040065369A

公开(公告)日：2004-07-22

申请号：KR1020030002314

申请日：2003-01-14

Applicant: 학교법인연세대학교

Inventor： 김중현 ,  이혜원 ,  최성욱

IPC: C12N5/00

CPC classification number: A61L27/56 ,  A61F2002/30762 ,  A61F2002/30766 ,  A61L27/20 ,  C12N5/0068 ,  C12N2533/40 ,  C12N2533/74 ,  C08L5/04

Abstract: PURPOSE: Biodegradable dual porous scaffold wrapped with a semi-permeable membrane and tissue cell culture using the same are provided, thereby selectively supplying nutrients by transporting only outside nutrients into the inner of the scaffold and discharging waste matters to the outside of the scaffold, and uniformly growing the tissue cells over the total of scaffold by combining small-sized scaffold to form a certain shaped bio-tissue. CONSTITUTION: The biodegradable dual porous scaffold which regenerates bio-tissues is wrapped with a semi-permeable membrane selected from alginate, polysaccharides, chitosan, agar powder or gelatin, wherein the biodegradable dual porous scaffold has the size of 1 to 3 mm. The method for preparing the biodegradable dual porous scaffold wrapped with a semi-permeable membrane comprises the steps of: arranging at least one scaffold in a mold having a desirable shape and size; adding a mixed solution of cross linking agents and semi-permeable membrane producing agents to the mold to form the semi-permeable membrane on the biodegradable dual porous scaffold, wherein the cross linking agent is selected from calcium chloride, tripolyphosphate and glutaaldehyde; and the mold is composed of teflon. A method for producing the bio-tissue comprises the steps of: transplanting a tissue cell into at least one scaffold; arranging the scaffold in a vessel prepared with a mold; adding the cross linking agent and semi-permeable membrane producing agent into the vessel; and supplying nutrients to the inside of the scaffold.

Abstract translation: 目的：提供用半透膜包裹的生物可降解的双重多孔支架，并使用其进行组织细胞培养，从而通过仅将外部营养物质运送到脚手架的内部并将废物排放到脚手架的外部来选择性地供应营养物质， 通过组合小尺寸支架以形成一定形状的生物组织，将组织细胞均匀地生长在总共的支架上。 构成：再生生物组织的可生物降解的双重多孔支架用选自藻酸盐，多糖，壳聚糖，琼脂粉或明胶的半透膜包裹，其中可生物降解的双重多孔支架的尺寸为1〜3mm。 制备用半透膜包裹的可生物降解的双重多孔支架的方法包括以下步骤：在具有期望的形状和尺寸的模具中布置至少一个支架; 将交联剂和半渗透膜生成剂的混合溶液加入到模具中以在可生物降解的双重多孔支架上形成半透膜，其中交联剂选自氯化钙，三聚磷酸盐和戊二醛; 模具由特氟龙组成。 生物组织的制备方法包括以下步骤：将组织细胞移植到至少一个支架中; 将支架放置在用模具制备的容器中; 将交联剂和半渗透膜生成剂加入到容器中; 并向脚手架的内部提供营养物质。

公开(公告)号：KR100441082B1

公开(公告)日：2004-07-21

申请号：KR1020020045237

申请日：2002-07-31

Applicant: 학교법인연세대학교

Inventor： 김정우 ,  이원종 ,  박우찬 ,  김형래 ,  한탁돈 ,  양성봉

IPC: G06T17/10

Abstract: PURPOSE: A three-dimensional texture based volume graphic structure using a visibility-ordered division rendering algorithm and a method therefor are provided to prevent lowering of performance and reduce the size of a required bandwidth. CONSTITUTION: A volume divider(20) decides the size of division volume regions and an order for processing through view point plane of one volume data, and the size and position information of volume information, and generates a three-dimensional texture map. A section generator(40) generates sections of the divided regions by receiving position information of the divided regions and the number of sections per divided region. A geometry operation unit(50) geometrically operates the sections. A three-dimensional texture mapping(60) generates the sections into preliminarily generated three-dimensional texture through the volume information of the corresponding region. An alpha blender(70) alpha-blends the sections one by one. A pixel cache(80) reads the corresponding section information from a frame memory(100) storing the blended section information by the section units to store the read section information, and is used as a cache between the alpha blender and the frame memory.

Abstract translation: 目的：提供一种基于三维纹理的体积图形结构，其使用可见性 - 有序分割呈现算法及其方法，以防止性能降低和减小所需带宽的大小。 组成：体积分割器（20）决定划分体积区域的大小和通过一个体数据的视点平面进行处理的顺序以及体积信息的大小和位置信息，并产生三维纹理图。 区段生成器（40）通过接收分割区域的位置信息和每个分割区域的区段数量来生成分割区域的区段。 几何操作单元（50）几何地操作这些部分。 三维纹理映射（60）通过相应区域的体积信息将区域生成为预先生成的三维纹理。 一台阿尔法搅拌器（70）逐个将各部分混合。 像素高速缓冲存储器（80）从由区段单元存储混合区段信息的帧存储器（100）读取对应的区段信息以存储所读取的区段信息，并用作阿尔法混合器与帧存储器之间的高速缓存。

公开(公告)号：KR100441081B1

公开(公告)日：2004-07-21

申请号：KR1020020045235

申请日：2002-07-31

Applicant: 학교법인연세대학교

Inventor： 이승기 ,  박우찬 ,  한탁돈 ,  이문기

IPC: G06T17/00 ,  G06T1/00

Abstract: PURPOSE: A method for calculating a trigonometric function using a linear equation is provided to reduce an error range through a linear equation, thereby promptly generating video of better quality. CONSTITUTION: A section of an X-axis in a trigonometric function curved surface is equally divided. Values of crossing points where vertical straight lines at boundary points of the divided sections cross the trigonometric function curved surface are obtained. Values of a trigonometric function to values of the sections are obtained by using a straight line equation connecting neighboring points in the obtained crossing points. Color values of fragments are decided by the obtained values of the trigonometric function. The section of the X-axis in a trigonometric function curved surface ranges from 0 to 90 deg.

Abstract translation: 目的：提供一种使用线性方程来计算三角函数的方法，以通过线性方程来减小误差范围，由此迅速生成更好质量的视频。 构成：三角函数曲面中的X轴的一部分被等分。 获得分割部分的边界点处的垂直直线与三角函数曲面交叉的交点的值。 通过使用连接所获得的交叉点中的相邻点的直线方程来获得三角函数对各部分的值的值。 碎片的颜色值由获得的三角函数值决定。 三角函数曲面中X轴的截面范围为0到90度。

公开(公告)号：KR100434999B1

公开(公告)日：2004-06-16

申请号：KR1020030013516

申请日：2003-03-04

Applicant: 학교법인연세대학교

Inventor： 홍준표

IPC: B22D27/02

Abstract: PURPOSE: A method and an apparatus for manufacturing semi-solid metal slurry are provided to obtain more fine and uniformed spheroidized grains, improve energy efficiency, reduce manufacturing cost, improve mechanical properties, simplify casting process, shorten manufacturing period of time, shortly manufacture semi-solid metal slurry having high quality and improve connection with succeeding processes. CONSTITUTION: The method for manufacturing semi-solid metal slurry comprises a step of arranging a slurry manufacturing container inside a certain space part; a step of impressing an electromagnetic field to the space part and injecting molten metal into the slurry manufacturing container; and a step of transferring the slurry manufacturing container to the outside of the space part, wherein the electromagnetic field is impressed to the space part before injecting molten metal into the slurry manufacturing container, wherein the step of arranging the slurry manufacturing container in the space part is performed after the electromagnetic field is impressed to the space part, wherein the electromagnetic field is impressed to the space part at the same time when the molten metal is injected into the slurry manufacturing container, wherein the electromagnetic field is impressed to the space part while the molten metal is being injected into the slurry manufacturing container, wherein the electromagnetic field is continuously impressed to the space part until a solid phase ratio of the molten metal in the slurry manufacturing container reaches 0.001 to 0.7.

Abstract translation: 目的：提供一种制备半固态金属浆料的方法和设备，以获得更细且均匀的球化颗粒，提高能量效率，降低制造成本，改善机械性能，简化铸造工艺，缩短制造时间，短时间制造半成品 - 高质量的固体金属浆料并改善与后续工艺的连接。 组成：半固态金属浆料的制造方法包括将浆料制造容器布置在特定空间部分内的步骤; 向空间部分施加电磁场并将熔融金属注入浆料制造容器的步骤; 以及将所述浆料制造容器移送到所述空间部分的外部的步骤，其中，在将所述熔融金属注入到所述浆料制造容器之前，所述电磁场被施加到所述空间部分，其中，将所述浆料制造容器布置在所述空间部分 是在将电磁场施加到空间部分之后执行的，其中，当熔融金属被注入到浆料制造容器中时，电磁场被施加到空间部分，其中电磁场被施加到空间部分而同时 熔融金属被注入到浆料制造容器中，其中电磁场连续地施加到空间部分，直到浆料制造容器中的熔融金属的固相比达到0.001到0.7。

公开(公告)号：KR100431375B1

公开(公告)日：2004-05-13

申请号：KR1020030072055

申请日：2003-10-16

Applicant: 학교법인연세대학교 ,  (주) 탑메디오피아

Inventor： 이경중 ,  권오윤 ,  송미혜

IPC: A61B5/00

Abstract: PURPOSE: A portable digital pressure algometer is provided to measure easily the pain of each part of human body by forming the digital pressure algometer by means of a digital method. CONSTITUTION: A portable digital pressure algometer includes a pressure sensing portion(100), an A/D converter(200), a data analysis portion(400), a data display portion(500), and a control portion(300). The pressure sensing portion(100) output an electric signal according to the pressure. The A/D converter(200) is used for converting the output signal of the pressure sensing portion(100) to a digital signal. The data analysis portion(400) converts the output signal of the A/D converter(200) to a predetermined value. The data display portion(500) displays an output signal of the data analysis portion(400). The control portion(300) controls the A/D converter(200), the data analysis portion(400), and the data display portion(500). The portable digital pain detector further includes a start switch(701) and a power down mode control portion(600). The power down mode control portion(600) switches a slip mode to an operating mode or the operating mode to slip mode when the start switch(701) is turned on or turned off.

Abstract translation: 用途：便携式数字压力测力计用于通过数字方法形成数字压力测力计，轻松测量人体各部位的疼痛程度。 构成：一种便携式数字压力测力计包括压力传感部分（100），A / D转换器（200），数据分析部分（400），数据显示部分（500）和控制部分（300）。 压力感测部分（100）根据压力输出电信号。 A / D转换器（200）用于将压力感测部分（100）的输出信号转换为数字信号。 数据分析部分（400）将A / D转换器（200）的输出信号转换为预定值。 数据显示部分（500）显示数据分析部分（400）的输出信号。 控制部分（300）控制A / D转换器（200），数据分析部分（400）和数据显示部分（500）。 便携式数字疼痛检测器还包括启动开关（701）和断电模式控制部分（600）。 当启动开关（701）打开或关闭时，断电模式控制部分（600）将打滑模式切换到操作模式或将操作模式切换到打滑模式。

公开(公告)号：KR1020040027266A

公开(公告)日：2004-04-01

申请号：KR1020030013517

申请日：2003-03-04

Applicant: 학교법인연세대학교

Inventor： 홍준표

IPC: B22D27/02

CPC classification number: B22D27/02 ,  B22D17/007 ,  B22D27/04 ,  C22C1/005

Abstract: PURPOSE: A method and an apparatus for manufacturing semi-solid metal slurry are provided to obtain more fine and uniformed spheroidized grains, improve energy efficiency, reduce manufacturing cost, improve mechanical properties, simplify casting process, shorten manufacturing period of time, shortly manufacture semi-solid metal slurry having high quality and improve connection with succeeding processes. CONSTITUTION: The method for manufacturing semi-solid metal slurry comprises a step of arranging a slurry manufacturing container inside a certain space part; a step of impressing an electromagnetic field to the space part and injecting molten metal into the slurry manufacturing container; and a step of transferring the slurry manufacturing container to the outside of the space part, wherein the electromagnetic field is impressed to the space part before injecting molten metal into the slurry manufacturing container, wherein the step of arranging the slurry manufacturing container in the space part is performed after the electromagnetic field is impressed to the space part, wherein the electromagnetic field is impressed to the space part at the same time when the molten metal is injected into the slurry manufacturing container, wherein the electromagnetic field is impressed to the space part while the molten metal is being injected into the slurry manufacturing container, wherein the electromagnetic field is continuously impressed to the space part until a solid phase ratio of the molten metal in the slurry manufacturing container reaches 0.001 to 0.7.

Abstract translation: 目的：提供半固体金属浆料的制造方法和装置，以获得更精细，均匀的球状颗粒，提高能源利用效率，降低制造成本，提高机械性能，简化铸造工艺，缩短制造周期，缩短制造半 固体金属浆料具有高质量并改善与后续工艺的连接。 构成：半固体金属浆料的制造方法包括将浆料制造容器配置在特定的空间部内的工序; 向空间部分施加电磁场并将熔融金属注入到浆料制造容器中的步骤; 以及将浆料制造容器转移到空间部分的外部的步骤，其中在将熔融金属注入到浆料制造容器之前，将电磁场施加到空间部分，其中将浆料制造容器设置在空间部分中的步骤 在电磁场被施加到空间部分之后进行，其中当将熔融金属注入到浆料制造容器中时，电磁场被施加到空间部分，其中电磁场被施加到空间部分，同时 熔融金属被注入到浆料制造容器中，其中电磁场连续地施加到空间部分，直到浆料制造容器中的熔融金属的固相比达到0.001至0.7。

公开(公告)号：KR1020040027211A

公开(公告)日：2004-04-01

申请号：KR1020020058990

申请日：2002-09-27

Applicant: 학교법인연세대학교

Inventor： 김중현 ,  이준영

IPC: C08G73/00

CPC classification number: Y02P20/544

Abstract: PURPOSE: A method for preparing a porous polyimide by using supercritical fluid is provided, to allow the size of pores to be controlled and to simplify processes. CONSTITUTION: The method comprises the steps of dissolving a dianhydride and a diisocyanate in an organic solvent to prepare a solution containing a polyimide precursor; drying the solution to obtain a polyimide precursor; carrying out imidation of the polyimide precursor under the condition of a temperature of 40-200 deg.C and a pressure of 500-5,000 psi for 1-48 hours to produce a polyimide, wherein supercritical carbon dioxide is introduced to swell the produced polyimide; and discharging the supercritical carbon dioxide outside when the imidation is terminated. Preferably the solution containing a polyimide precursor is spin-coated to form the thin film of a polyimide precursor. Preferably the dianhydride is represented by the formula 1, wherein M is a tetravalent aryl group; and the diisocyanate is represented by O=C=N-R-N=C=O, wherein R is a diphenylmethylene, hexylene, isophorone or toluene group.

Abstract translation: 目的：提供通过使用超临界流体制备多孔聚酰亚胺的方法，以允许控制孔的尺寸并简化工艺。 方案：该方法包括将二酐和二异氰酸酯溶解在有机溶剂中以制备含有聚酰亚胺前体的溶液的步骤; 干燥溶液得到聚酰亚胺前体; 在40〜200℃的温度和500〜5000psi的压力下进行1-48小时的聚酰亚胺前体的酰亚胺化反应，得到聚酰亚胺，其中引入超临界二氧化碳以使生成的聚酰亚胺溶胀; 并且当酰亚胺化终止时将超临界二氧化碳排出到外面。 优选地，将包含聚酰亚胺前体的溶液旋涂以形成聚酰亚胺前体的薄膜。 优选地，二酐由式1表示，其中M是四价芳基; 并且二异氰酸酯由O = C = N-R-N = C = O表示，其中R是二苯基亚甲基，亚己基，异佛尔酮或甲苯基。

公开(公告)号：KR200345483Y1

公开(公告)日：2004-03-19

申请号：KR2020030038255

申请日：2003-12-08

Applicant: 학교법인연세대학교

Inventor： 김법민 ,  이윤선

IPC: A61G1/013

Abstract: 본 고안은 이송장치에 관한 것으로, 특히 이송물 및 이송될 사람을 쉽게 이송장치로 옮길 수 있으며, 휴대가 간편하고 안정성이 높은 조립식 이송장치를 제공함을 그 목적으로 하고 있다.
본 고안은 제 1지지봉, 제2 지지봉, 바닥단위부재를 구비하며, 상기 바닥 단위부재는 관통공을 가지는 제1단부와 걸쇠부를 구비하는 제2단부를 구비하고, 상기 바닥 단위부재의 제1단부의 관통공을 상기 제1지지봉에 끼우고 상기 바닥 단위부재의 제2단부의 걸쇠부를 상기 제2 지지봉의 홈에 걸리게되어 있는 조립식 이송장치에 있어서, 상기 제1 지지봉 및 상기 바닥 단위부재의 제1단부는 삽입공을 가지며, 상기 삽입공들에 스톱퍼가 끼워져 상기 제1 지지봉과 상기 바닥 단위부재의 제1단부가 고정되는 제1단부 고정수단; 상기 바닥 단위부재의 제2단부는 맞주름 형태의 돌기를 구비하여 상기 돌기가 제2지지봉의 홈에 걸려지게되어 있는 제2단부 고정수단을 구비한다.

公开(公告)号：KR1020040018598A

公开(公告)日：2004-03-04

申请号：KR1020020049979

申请日：2002-08-23

Applicant: 코웰에셋(주) ,  학교법인연세대학교

Inventor： 이준행

IPC: C07K19/00

CPC classification number: C07K14/4703 ,  A61K38/00 ,  A61K38/1709 ,  C07K7/06 ,  C07K2319/00 ,  C07K2319/01 ,  C12N15/62 ,  C12N15/70

Abstract: PURPOSE: A Tat-PTEN fusion protein and a process for preparing the same and the use thereof are provided. The Tat-PTEN fusion protein penetrates subconjunctival fibroblast and inhibits TGF-β(transforming growth factor-β) signal transmission. Therefore, the apoptosis of the subconjunctival fibroblast can be induced and the formation of a scar can be inhibited. CONSTITUTION: A Tat-PTEN fusion protein contains PTEN(phosphatase and tensin homologue deleted from chromosome 10) protein and protein transduction domain (SEQ ID NO:1) of HIV-1 Tat protein bound to the amino terminal of the PTEN protein, wherein the Tat-PTEN fusion protein has the amino acid sequence set forth in SEQ ID NO: 12. A recombinant polynucleotide comprises a DNA sequence encoding the Tat-PTEN fusion protein, wherein the recombinant polynucleotide has the nucleotide sequence set forth in SEQ ID NO: 11. A vector expressing the Tat-PTEN fusion protein contains the recombinant polynucleotide, wherein the vector has a restriction enzyme map shown in figure 3. A process for preparing the Tat-PTEN fusion protein comprises expressing the vector in a microorganism and purifying the expressed Tat-PTEN fusion protein, wherein the microorganism is E. coli.

Abstract translation: 目的：提供Tat-PTEN融合蛋白及其制备方法及其应用。 Tat-PTEN融合蛋白穿透结膜下成纤维细胞，抑制TGF-β（转化生长因子-β）信号传递。 因此，可以诱导结膜下成纤维细胞的凋亡，可以抑制瘢痕的形成。 构成：Tat-PTEN融合蛋白含有与PTEN蛋白的氨基末端结合的HIV-1 Tat蛋白质的PTEN（从染色体10缺失的磷酸酶和张力蛋白同源物）蛋白质和蛋白质转导结构域（SEQ ID NO：1），其中 Tat-PTEN融合蛋白具有SEQ ID NO：12所示的氨基酸序列。重组多核苷酸包含编码Tat-PTEN融合蛋白的DNA序列，其中重组多核苷酸具有SEQ ID NO：11所示的核苷酸序列 表达Tat-PTEN融合蛋白的载体含有重组多核苷酸，其中载体具有图3所示的限制性内切酶图谱。制备Tat-PTEN融合蛋白的方法包括将载体表达在微生物中并纯化表达的Tat -PTEN融合蛋白，其中所述微生物是大肠杆菌。

公开(公告)号：KR100420860B1

公开(公告)日：2004-03-02

申请号：KR1020010048606

申请日：2001-08-13

Applicant: 학교법인연세대학교

Inventor： 이현석 ,  이택섭 ,  박우찬 ,  양성봉 ,  한탁돈

IPC: G06T17/00

Abstract: PURPOSE: A method of compressing a phase of three-dimensional graphic data using weighted vector sum is provided to compress three-dimensional graphic data in consideration of variations in previous data items to improve compression efficiency. CONSTITUTION: A start triangle is arbitrarily selected. Triangle data to be compressed is inputted(S50). Initial three points are set using one of vertexes of a triangle that was not processed is used as a start point, and the nth vertex is inputted(S52). The sum of vectors is estimated(S54). A difference between a weighted vector sum and actual vertexes is delta-encoded. A difference between an estimated value and an actual value is calculated and stored(S55). Huffman table is constructed on the basis of the delta-encoded value(S56). Huffman tag and encoding data are output. Huffman encoding is performed using the Huffman table and the encoding result is output(S57,S58).

Abstract translation: 目的：提供一种使用加权矢量和来压缩三维图形数据的相位的方法，以考虑到先前数据项的变化来压缩三维图形数据以提高压缩效率。 组成：起始三角形是任意选择的。 输入要压缩的三角形数据（S50）。 使用未经处理的三角形的顶点之一设定初始三点作为起点，输入第N顶点（S52）。 矢量的总和被估计（S54）。 增量矢量和与实际顶点之间的差异是增量编码。 计算并存储估计值和实际值之间的差值（S55）。 霍夫曼表是基于增量编码值构建的（S56）。 输出霍夫曼标签和编码数据。 使用霍夫曼表执行霍夫曼编码，并输出编码结果（S57，S58）。