公开(公告)号：US10398377B2

公开(公告)日：2019-09-03

申请号：US15756410

申请日：2016-08-31

Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY

Inventor： Ichiro Amimori ,  Masao Nakajima ,  Takao Someya

IPC: A61B5/06 ,  A61B5/00 ,  H05K1/18 ,  A61B5/11 ,  H05K1/03 ,  H05K1/11 ,  H04Q9/00 ,  A41D1/00

Abstract: A connector substrate includes a base material, n first input terminals of m groups (m and n are an integer equal to or greater than 2) which are provided on the base material, n first output terminals which are provided on the base material, first wiring patterns which are disposed on or inside the base material and connect the first input terminals and the first output terminals, m second input terminals which are provided on the base material, m second output terminals which are provided on the base material, and second wiring patterns which are disposed on or inside the base material and connect the second input terminals and the second output terminals, in which a first end of each connector wiring constituting the first wiring pattern is connected to one of the n first input terminals constituting each group, and a second end is connected to one of the first output terminals.

公开(公告)号：US20190249236A1

公开(公告)日：2019-08-15

申请号：US16371766

申请日：2019-04-01

Applicant: Japan Science and Technology Agency

Inventor： Masayuki Su'etsugu ,  Hiroko Kobayashi

IPC: C12Q1/6844 ,  C12Q1/686 ,  C12Q1/6853 ,  C12P19/34 ,  C12N15/09 ,  C12N9/00 ,  C12N9/90 ,  C12N9/16 ,  C12N9/12

CPC classification number: C12Q1/6846 ,  C12N9/00 ,  C12N9/12 ,  C12N9/16 ,  C12N9/90 ,  C12N15/00 ,  C12N15/09 ,  C12P19/34 ,  C12Q1/6853 ,  C12Q1/686

Abstract: The present invention provides a method for easily and exponentially amplifying circular DNA, particularly long chain circular DNA, in a cell-free system. Specifically, the present invention provides a method for amplifying circular DNA in which circular DNA having a replication origin sequence (origin of chromosome (oriC)) is mixed with a reaction solution containing the following enzyme groups to form a reaction mixture, which is then reacted under an isothermal condition, the enzyme groups being:(1) a first enzyme group that catalyzes replication of circular DNA; (2) a second enzyme group that catalyzes an Okazaki fragment maturation and synthesizes two sister circular DNAs constituting a catenane and (3) a third enzyme group that catalyzes a separation of two sister circular DNAs.

公开(公告)号：US10381489B2

公开(公告)日：2019-08-13

申请号：US15764426

申请日：2016-09-27

Applicant: NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY ,  JAPAN SCIENCE AND TECHNOLOGY AGENCY

Inventor： Takashi Fukui ,  Katsuhiro Tomioka

IPC: H01L29/786 ,  H01L29/66 ,  H01L29/778 ,  H01L29/78 ,  H01L27/095 ,  H01L29/808 ,  H01L29/812 ,  H01L29/06 ,  H01L29/04 ,  H01L29/205

Abstract: The tunnel field effect transistor according to the present invention has: a channel; a source electrode connected directly or indirectly to one end of the channel; a drain electrode connected directly or indirectly to the other end of the channel; and a gate electrode for causing an electric field to act on the channel, generating a tunnel phenomenon at the source electrode-side joint part of the channel, and simultaneously generating a two-dimensional electron gas in the channel.

公开(公告)号：US10305052B2

公开(公告)日：2019-05-28

申请号：US15325943

申请日：2015-07-15

Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY

Inventor： Takanori Fukushima ,  Yoshiaki Shoji ,  Fumitaka Ishiwari ,  Tsuyoshi Sekitani ,  Takao Someya

IPC: H01L51/00 ,  C07C43/00 ,  H01B1/00 ,  H01L51/05 ,  H01B1/12 ,  C07C43/21 ,  H01L29/786 ,  C07C43/215 ,  C07C43/225

Abstract: The present invention pertains to: a Janus-type triptycene derivative which is capable of forming a self-assembled film which does not depend on the material quality of a substrate; a self-assembled film using said Janus-type triptycene derivative; a structure having said film on a surface thereof; a method for manufacturing said film; and an electronic device using said method.

公开(公告)号：US20190154682A1

公开(公告)日：2019-05-23

申请号：US16260413

申请日：2019-01-29

Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY

Inventor： Hiroyuki NOJI ,  Ryota IINO ,  Suguru ARAKI

IPC: G01N33/543 ,  G01N21/64 ,  B01L3/00

CPC classification number: G01N33/54386 ,  B01J2219/00317 ,  B01J2219/00466 ,  B01J2219/00619 ,  B01J2219/00621 ,  B01L3/502715 ,  B01L3/502761 ,  B01L3/50853 ,  B01L2200/0642 ,  B01L2200/0668 ,  B01L2200/12 ,  B01L2300/0627 ,  B01L2300/0819 ,  B01L2300/0829 ,  B01L2300/0858 ,  B01L2300/0877 ,  B01L2300/161 ,  B01L2300/165 ,  G01N21/6452 ,  G01N33/54306 ,  G01N33/54313

Abstract: This invention provides a technique enabling to detect target molecules of low concentration with high sensitivity. This invention includes (i) a step of introducing a hydrophilic solvent (42) containing beads (40),(41′) into a space (30) between (a) a lower layer section (10) including a plurality of receptacles (13) each of which is capable of storing only one of the beads (41),(41′) and which are separated from each other by a side wall (12) having a hydrophobic upper surface and (b) an upper layer section (20) facing a surface of the lower layer section (10) on which surface the plurality of receptacles (13) are provided; and (ii) a step of introducing a hydrophobic solvent (43) into the space (30), the step (ii) being carried out after the step (i).

公开(公告)号：US20190134609A1

公开(公告)日：2019-05-09

申请号：US16082489

申请日：2017-03-02

Applicant: Japan Science and Technology Agency

Inventor： Miho Yamauchi ,  Masaaki Sadakiyo ,  Sho Kitano ,  Shinichi Hata

IPC: B01J23/20 ,  B01J35/00 ,  C25B11/04 ,  C25B11/03 ,  C25B9/08 ,  C25B3/04

Abstract: A catalyst comprising: a titanium oxide having an anatase-type crystal structure, and having the vertices and the ridge lines, wherein in a single titanium oxide particle, a vertex density per unit surface area is 8.0×10−4 nm−2 or more, and a ridge line density per unit surface area is 5.0×10−2 nm or more, or a ridge line density per unit volume is 8.0×10−3 nm−2 or more. A complex comprising: a material having a porous structure; and said catalyst. A membrane electrode assembly comprising: an anode; cathode; and an electrolyte membrane, wherein the cathode carries said catalyst on at least a surface of the cathode.

公开(公告)号：US10280142B2

公开(公告)日：2019-05-07

申请号：US15819180

申请日：2017-11-21

Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY

Inventor： Yoichiro Kuninobu ,  Motomu Kanai ,  Haruka Ida ,  Mitsumi Nishi

IPC: C07D213/53 ,  B01J31/22 ,  C07F15/00 ,  B01J31/18

Abstract: There are provided a compound capable of being a novel ligand allowing regioselective borylation to be performed in the aromatic borylation reaction, and a catalyst using the same compound. There is provided a bipyridyl compound represented by a general formula (1): (wherein A represents a single bond, a vinylene group or an ethynylene group; X represents an oxygen atom or a sulfur atom; n pieces of R1 may be the same or different, and R1 represents a hydrogen atom, a halogen atom, an optionally substituted hydrocarbon group, an optionally substituted alkoxy group, an optionally substituted aryloxy group, an optionally substituted amino group, a cyano group, a nitro group, or an alkoxycarbonyl group, or two adjacent R1 may form a saturated or unsaturated ring structure optionally containing a hetero atom together with the carbon atoms bonded to the two R1; R2 represents a hydrogen atom, an optionally substituted hydrocarbon group, an optionally substituted alkoxy group, or an optionally substituted aryloxy group; and n represents a number of 1 to 4).

公开(公告)号：US20190075770A1

公开(公告)日：2019-03-14

申请号：US16061769

申请日：2016-11-29

Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY

Inventor： Takayuki SHINDO ,  Takayuki SAKURAI

IPC: A01K67/027 ,  C12N15/873

Abstract: The present invention provides a genetically modified non-human organism in which an expression level of Cas9 is high and a plurality of different genes or different locations in the same gene can be edited at the same time with high efficiency. The genetically modified non-human organism includes a nuclear genome having at least 3 copies of genes that code for Cas9 (CRISPR-associated 9). Egg cells of the present invention are derived from the genetically modified non-human organism having the nuclear genome into which at least 3 copies of genes that code for the Cas9 are introduced. Fertilized eggs of the present invention are obtained by fertilizing the egg cells and sperm derived from the same species of the organism. A method for modifying target genes includes a step of introducing a guide RNA into cells derived from the genetically modified non-human organism, the egg cells, or the fertilized eggs.

公开(公告)号：US20190064927A1

公开(公告)日：2019-02-28

申请号：US16152982

申请日：2018-10-05

Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY

Inventor： Susumu TACHI ,  Masashi NAKATANI ,  Katsunari SATO ,  Kouta MINAMIZAWA ,  Hiroyuki KAJIMOTO

IPC: G06F3/01 ,  H03K17/96 ,  G06F3/041 ,  G06F3/0354 ,  G06F15/18

Abstract: The purpose is to provide a tactile information conversion device, a tactile information conversion method, and a tactile information conversion program, which are usable for general purposes by presenting or sensing an arbitrary tactile feeling. In order to provide tactile information to an output unit capable of outputting physical quantities including electricity, force, temperature, vibration, and/or time and space, at least two or more of the physical quantities are selected according to a tactile feeling to be presented, tactile information for presenting the predetermined tactile feeling is generated based on the physical quantities that have been selected, and the tactile information that has been generated is output to the output unit.

公开(公告)号：US20190043322A1

公开(公告)日：2019-02-07

申请号：US16153008

申请日：2018-10-05

Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY

Inventor： Susumu TACHI ,  Masashi NAKATANI ,  Katsunari SATO ,  Kouta MINAMIZAWA ,  Hiroyuki KAJIMOTO

IPC: G08B6/00

Abstract: The purpose is to provide a device, method and program for tactile information conversion, and an element arrangement structure for presenting a plurality of types of stimuli that are capable of presenting a plurality of types of stimuli at one point in a concentrated manner from different points. One of the features is to determine a first stimulation point at which a first type of tactile stimulus is generated or generate the first type of tactile stimulus at the first stimulation point via the output unit and output tactile information for generating a second type of tactile stimulus via the output unit to the output unit at a second stimulation point separated within a temporally and/or spatially predetermined threshold value from the first stimulation point of the first type of tactile stimulus that has been determined or generated by a first stimulation unit.