公开(公告)号：IL159287D0

公开(公告)日：2004-06-01

申请号：IL15928702

申请日：2002-06-10

Applicant: UCB FARCHIM SA

IPC: A61J1/03 ,  A61K20060101 ,  A61K9/20 ,  A61K9/24 ,  A61K9/26 ,  A61K31/137 ,  A61K31/495 ,  A61K47/36 ,  A61K47/38 ,  A61P11/00 ,  A61P11/02 ,  A61P27/02 ,  A61P37/08 ,  A61K

Abstract: The present invention concerns a tablet comprising two distinct segments. More particularly, the invention relates to combinations of two pharmaceutical substances and methods of treatment of allergic disorders.

公开(公告)号：PL355944A1

公开(公告)日：2004-05-31

申请号：PL35594400

申请日：2000-12-15

Applicant: UCB FARCHIM SA

Inventor： LEUNG CHOI LEWIS SIU ,  BEATCH GREGORY N ,  PAGE CLIVE P

IPC: A61K31/135 ,  A61K31/14 ,  A61P11/14 ,  C07C215/40 ,  A61K31/404 ,  C07C217/14 ,  C07C217/18 ,  C07C217/30 ,  C07D209/08 ,  C07D211/14

Abstract: In one aspect, the present invention concerns the use of certain quaternary ammonium compounds as active ingredient in the manufacture of a medicament for use in the treatment aid/or prevention of cough in warm-blooded animals, including humans, such as compounds of formula Y-J-EAn - (I), wherein J is independently selected from a group represented by one of formulae (II), (III) and (IV).

公开(公告)号：DE69813839T2

公开(公告)日：2004-03-04

申请号：DE69813839

申请日：1998-09-03

Applicant: UCB FARCHIM SA

Inventor： MACLEOD A ,  QUASTEL M

IPC: A61K31/167 ,  A61P25/04 ,  A61K31/165 ,  H04L1/08

公开(公告)号：EE200200315A

公开(公告)日：2003-08-15

申请号：EEP200200315

申请日：2000-12-15

Applicant: UCB FARCHIM SA

Inventor： CHOI LEWIS SIU LEUNG ,  BEATCH GREGORY N ,  PAGE CLIVE P

IPC: A61K31/404 ,  A61K31/135 ,  A61K31/14 ,  A61P11/14 ,  C07C215/40 ,  C07C217/14 ,  C07C217/18 ,  C07C217/30 ,  C07D209/08 ,  C07D211/14

Abstract: In one aspect, the present invention concerns the use of certain quaternary ammonium compounds as active ingredient in the manufacture of a medicament for use in the treatment aid/or prevention of cough in warm-blooded animals, including humans, such as compounds of formula Y-J-EAn - (I), wherein J is independently selected from a group represented by one of formulae (II), (III) and (IV).

公开(公告)号：DE69813839D1

公开(公告)日：2003-05-28

申请号：DE69813839

申请日：1998-09-03

Applicant: UCB FARCHIM SA

Inventor： MACLEOD A ,  QUASTEL M

IPC: A61K31/167 ,  A61P25/04 ,  A61K31/165 ,  H04L1/08

公开(公告)号：BG107016A

公开(公告)日：2003-04-30

申请号：BG10701602

申请日：2002-08-20

Applicant: UCB FARCHIM SA

Inventor： SURTEES JOHN ,  MARMON VIOLETA ,  DIFFERDING EDMOND ,  ZIMMERMANN VINCENT

IPC: C07D401/04 ,  A61K31/4015 ,  A61K31/4025 ,  A61K31/41 ,  A61K31/4178 ,  A61K31/4188 ,  A61K31/4192 ,  A61K31/4196 ,  A61K31/422 ,  A61K31/4245 ,  A61K31/427 ,  A61K31/433 ,  A61K31/4439 ,  A61K31/497 ,  A61K31/506 ,  A61K31/541 ,  A61P9/00 ,  A61P9/06 ,  A61P9/10 ,  A61P11/00 ,  A61P11/06 ,  A61P21/00 ,  A61P25/00 ,  A61P25/04 ,  A61P25/06 ,  A61P25/08 ,  A61P25/14 ,  A61P25/16 ,  A61P25/20 ,  A61P25/22 ,  A61P25/24 ,  A61P25/28 ,  A61P25/30 ,  A61P27/16 ,  A61P37/08 ,  C07B61/00 ,  C07C237/06 ,  C07C237/12 ,  C07D207/26 ,  C07D207/27 ,  C07D207/273 ,  C07D207/277 ,  C07D307/33 ,  C07D401/06 ,  C07D403/04 ,  C07D403/06 ,  C07D403/12 ,  C07D405/04 ,  C07D409/04 ,  C07D413/04 ,  C07D417/04 ,  C07D495/04

Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives and a process for preparing them and their uses. The invention also concerns a process of preparing alpha-ethyl-2-oxo-1-pyrrolidine acetamide derivatives from unsaturated 2-oxo-1-pyrrolidine derivatives. Particularly the invention concerns novel intermediates and their use in methods for the preparation of S-alpha-ethyl-2-oxo-1-pyrrolidine acetamide. 13 claims

公开(公告)号：BG106816A

公开(公告)日：2003-04-30

申请号：BG10681602

申请日：2002-06-12

Applicant: UCB FARCHIM SA

Inventor： CHOI LEWIS S ,  BEATCH GREGORY N ,  PAGE CLIVE P

IPC: A61K31/16 ,  A61K31/452 ,  A61P11/14 ,  C07D211/60 ,  C07D295/02 ,  C07D295/15

Abstract: In one aspect, the present invention concerns the use of certain cyclic quaternary ammonium compounds as active ingredients in the manufacture of medicaments for use in the treatment and/or of cough in warm-blooded animals, including humans, such as compounds of formula wherein n is an integer of from 0 to 4; R1 and E are independently selected from -CH2-R16 and a group represented by the formula 27 claims, 3 figures

公开(公告)号：BG106814A

公开(公告)日：2003-04-30

申请号：BG10681402

申请日：2002-06-12

Applicant: UCB FARCHIM SA

Inventor： CHOI LEWIS S ,  BEATCH GREGORY N ,  PAGE CLIVE P

IPC: C07D295/12 ,  A61K31/16 ,  A61K31/166 ,  A61K31/24 ,  A61K31/40 ,  A61K31/445 ,  A61P11/14 ,  C07C219/14 ,  C07C219/26 ,  C07C229/60 ,  C07C229/64 ,  C07C237/34 ,  C07D211/14 ,  C07D295/08 ,  C07D295/088 ,  C07D295/10 ,  C07D295/13 ,  C07D295/18 ,  C07D295/195

Abstract: In one aspect the present invention concerns the use of certain quaternary ammonium compounds as active ingredient in the manufacture for use in the treatment and/or prevention of cough in warm-blooded animals, including humans, such as compounds of the following formula Y - J - E An- wherein J is independently selected from a group represented by one of formulae 74 claims, 3 figures

公开(公告)号：HU0204014A2

公开(公告)日：2003-03-28

申请号：HU0204014

申请日：2000-12-15

Applicant: UCB FARCHIM SA

Inventor： BEATCH GREGORY N ,  CHOI LEWIS SIU LEUNG ,  PAGE CLIVE P

IPC: C07D295/12 ,  A61K31/16 ,  A61K31/166 ,  A61K31/24 ,  A61K31/40 ,  A61K31/445 ,  A61P11/14 ,  C07C219/14 ,  C07C219/26 ,  C07C229/60 ,  C07C229/64 ,  C07C237/34 ,  C07D211/14 ,  C07D295/08 ,  C07D295/088 ,  C07D295/10 ,  C07D295/13 ,  C07D295/18 ,  C07D295/195

Abstract: In one aspect, the present invention concerns the use of certain quaternary ammonium compounds as active ingredient in the manufacture of a medicament for use in the treatment and/or prevention of cough in warm-blooded animals, including humans, such as compounds of the following formula (I): Y-J-E An wherein J is independently selected from a group represented by one of formulae (II), (III) and (IV).

公开(公告)号：IL150180D0

公开(公告)日：2002-12-01

申请号：IL15018000

申请日：2000-12-15

Applicant: UCB FARCHIM SA

IPC: C07D295/12 ,  A61K31/16 ,  A61K31/166 ,  A61K31/24 ,  A61K31/40 ,  A61K31/445 ,  A61P11/14 ,  C07C219/14 ,  C07C219/26 ,  C07C229/60 ,  C07C229/64 ,  C07C237/34 ,  C07D211/14 ,  C07D295/08 ,  C07D295/088 ,  C07D295/10 ,  C07D295/13 ,  C07D295/18 ,  C07D295/195 ,  C07C

Abstract: In one aspect, the present invention concerns the use of certain quaternary ammonium compounds as active ingredient in the manufacture of a medicament for use in the treatment and/or prevention of cough in warm-blooded animals, including humans, such as compounds of the following formula (I): Y-J-E An wherein J is independently selected from a group represented by one of formulae (II), (III) and (IV).