公开(公告)号：PL355944A1

公开(公告)日：2004-05-31

申请号：PL35594400

申请日：2000-12-15

Applicant: UCB FARCHIM SA

Inventor： LEUNG CHOI LEWIS SIU ,  BEATCH GREGORY N ,  PAGE CLIVE P

IPC: A61K31/135 ,  A61K31/14 ,  A61P11/14 ,  C07C215/40 ,  A61K31/404 ,  C07C217/14 ,  C07C217/18 ,  C07C217/30 ,  C07D209/08 ,  C07D211/14

Abstract: In one aspect, the present invention concerns the use of certain quaternary ammonium compounds as active ingredient in the manufacture of a medicament for use in the treatment aid/or prevention of cough in warm-blooded animals, including humans, such as compounds of formula Y-J-EAn - (I), wherein J is independently selected from a group represented by one of formulae (II), (III) and (IV).