公开(公告)号：US20240033998A1

公开(公告)日：2024-02-01

申请号：US18022779

申请日：2021-08-27

Applicant: Patrick Neuvel ,  Universiteit Twente

Inventor： Stefano Stramigioli ,  Alexander Dijkshoorn ,  Gijsbertus Jacobus Maria Krijnen ,  Patrick Neuvel

IPC: B29C64/393 ,  B22F10/85 ,  B33Y10/00 ,  B33Y30/00 ,  B33Y50/02

CPC classification number: B29C64/393 ,  B22F10/85 ,  B33Y10/00 ,  B33Y30/00 ,  B33Y50/02 ,  B29K2995/0005

Abstract: A system for additive manufacturing of a product from an electrically conductive depositable material. The system comprises a support element, a material addition system, and two electrodes. The support element supports the product, wherein the two electrodes comprise electrodes configured at a surface of the support element. The material addition system deposits the material at one or more of (i) the support element and (ii) deposited material, thereby forming the product. Any one of the electrodes is configured for (i) electrically contacting the material being deposited or (ii) electrically contacting the deposited material, during depositing of the material. (i) the material is deposited with a portion of the deposited material and arranged between the electrode and another one of the electrodes to define an electrically conductive path. Alternatively, (ii) a portion of the deposited material is arranged between the electrode and another one of the electrodes to define the electrically conductive path.

公开(公告)号：US20240025965A1

公开(公告)日：2024-01-25

申请号：US18295068

申请日：2023-04-03

Applicant: Jai Prakash ,  Universiteit Twente

Inventor： Jai Prakash

IPC: C07K14/705 ,  A61K49/00 ,  C07K14/78 ,  C07K7/08 ,  C07K7/06 ,  A61K47/62 ,  A61K47/60 ,  A61P1/16

CPC classification number: C07K14/70546 ,  A61K49/0045 ,  C07K14/78 ,  C07K7/08 ,  C07K7/06 ,  A61K47/62 ,  A61K47/60 ,  A61P1/16 ,  A61K49/0056 ,  A61K38/00

Abstract: The disclosure relates to integrin binding peptides, pharmaceutical compositions comprising the peptides and to uses thereof as therapeutic, diagnostic, imaging and targeting agents.

公开(公告)号：US20230363666A1

公开(公告)日：2023-11-16

申请号：US18028998

申请日：2021-09-27

Applicant: UNIVERSITEIT TWENTE

Inventor： Rob HAGMEIJER ,  Rutger Hendrik Johan HEBBINK

IPC: A61B5/087 ,  A61B5/091

CPC classification number: A61B5/087 ,  A61B5/091 ,  A61B2562/0247 ,  A61B5/742

Abstract: A method for determining a scaled respiratory flow rate and volume during respiration of a patient includes a) successively determining a plurality of values for a difference between a pressure in at least a first location in an upper respiratory tract of the patient and a reference pressure, b) deriving the scaled respiratory flow rate from the plurality of values for the pressure difference by using a first relationship, c) deriving the scaled respiratory volume from the plurality of values for the pressure difference by using a second relationship, and d) displaying the scaled respiratory flow rate derived in step b) and the scaled respiratory volume derived in step c) or a further variable derived from the scaled respiratory flow rate and volume in a graphical representation. Step a) is performed during tidal breathing of the patient. A system for performing the aforementioned method.

公开(公告)号：US11806676B2

公开(公告)日：2023-11-07

申请号：US17262301

申请日：2019-07-25

Applicant: Universiteit Twente

Inventor： Dimitrios Stamatialis ,  Ilaria Geremia

IPC: B01D69/14 ,  B01D69/02 ,  B01D71/62 ,  B01D71/68 ,  A61M1/34 ,  A61M1/16 ,  B01D71/02 ,  B01J20/20 ,  B01J20/28 ,  B01J20/32

CPC classification number: B01D69/147 ,  A61M1/34 ,  B01D69/02 ,  B01D71/021 ,  B01D71/62 ,  B01D71/68 ,  B01J20/20 ,  B01J20/28026 ,  B01J20/28038 ,  B01J20/28085 ,  B01J20/321 ,  B01J20/324 ,  B01J20/3212 ,  A61M1/1696 ,  B01D2325/36

Abstract: Disclosed are compositions for use in the simultaneous removal of endotoxins from dialysate and uremic solutes from blood during the treatment of patients. The treatment is selected from the group consisting of hemodialysis and hemodiafiltration. The compositions comprise sorbent particles embedded in a membrane comprising a polymer and a hydrophilic additive.

公开(公告)号：US20230236269A1

公开(公告)日：2023-07-27

申请号：US18000514

申请日：2021-06-02

Applicant: Universiteit Twente

Inventor： Melissa Mathilde van de Loosdrecht ,  Hendrikus Johannes Gradus Krooshoop ,  Bernard ten Haken ,  Lejla Alic

IPC: G01R33/12 ,  A61B5/06

CPC classification number: G01R33/1276 ,  A61B5/062

Abstract: The invention relates to a method and apparatus for detecting superparamagnetic material. The method comprises applying, by an excitation coil, a magnetic field during a first period to an object to modulate a magnetization of the superparamagnetic material, the magnetic field comprising a first component with a first frequency; positioning a sensing device at a first position from the excitation coil receiving a first signal by a first detection sub-coil in the sensing device and a second signal by a second detection-sub-coil in the sensing device; determining a sensor signal from the first signal and the second signal; determining a detection signal based on the sensor signal; determining a parameter indicating an amount of superparamagnetic material by dividing the detection signal by the first signal, and repeating steps to at at least one different position in order to determine a location where the parameter has a maximal value.

公开(公告)号：US11634470B2

公开(公告)日：2023-04-25

申请号：US15770105

申请日：2016-10-21

Applicant: Universiteit Twente ,  Jai Prakash

Inventor： Jai Prakash

IPC: A61K38/00 ,  C07K14/705 ,  A61K49/00 ,  C07K14/78 ,  C07K7/08 ,  C07K7/06 ,  A61K47/62 ,  A61K47/60 ,  A61P1/16

Abstract: The disclosure relates to integrin binding peptides, pharmaceutical compositions comprising the peptides and to uses thereof as therapeutic, diagnostic, imaging and targeting agents.

公开(公告)号：US20230056762A1

公开(公告)日：2023-02-23

申请号：US17796892

申请日：2021-02-03

Applicant: VRIJE UNIVERSITEIT BRUSSEL ,  UNIVERSITEIT TWENTE

Inventor： Wim DE MALSCHE ,  Eiko WESTERBEEK ,  Jan EIJKEL ,  Wouter OLTHUIS

IPC: B01L3/00

Abstract: A fluidic device for processing a fluid or species therein is described. The device comprises a 3D channel including an inlet for receiving a sample fluid and an outlet for outputting the sample fluid. The channel is adapted for guiding flow of the sample fluid in an axial direction from the inlet to the outlet. The channel includes at least two side walls. The device also has a controllable flow inducer having electrodes for inducing, when the sample fluid is flowing through the channel, a motion of the sample fluid in the channel in a plane substantially orthogonal to the axial direction. Along at least one of the side walls at least part of the electrodes are formed by alternatingly at least an electrically conducting portion, an electrically insulating portion and a further electrically conducting portion.

公开(公告)号：US20230025035A1

公开(公告)日：2023-01-26

申请号：US17782983

申请日：2020-12-04

Applicant: UNIVERSITEIT TWENTE

Inventor： Rebecca SAIVE

IPC: H02S40/22

Abstract: A photovoltaic solar power plant assembly and a method of using said assembly to generate power are disclosed. The assembly includes an array of photovoltaic solar modules arranged in a solar module surface, and an optical structure for redirecting light towards said solar module surface, having a redirected light emitting surface. The optical structure includes: a planar optical waveguide which has a parallel first and second planar waveguide surfaces, wherein the first planar waveguide surface extends parallel to the redirected light emitting surface, wherein the first planar waveguide surface is at least partially covered by a photonic layer which is configured to provide an angular restriction of a light emission from the planar waveguide through the redirected light emitting surface, and a light scattering and/or luminescent material, which material is arranged as particles in the planar optical waveguide and/or in a layer which at least partially covers the second planar waveguide surface.

公开(公告)号：US11465103B2

公开(公告)日：2022-10-11

申请号：US15972273

申请日：2018-05-07

Applicant: Universiteit Twente

Inventor： Wiebe Matthijs de Vos

IPC: B01D71/68 ,  B01D71/32 ,  B01D71/26 ,  C08J5/22 ,  B01D71/40 ,  B01D67/00 ,  B01D69/02 ,  B01D69/12 ,  B01D69/14

Abstract: The invention is in the field of methods for preparing polymer films, and of such polymer films. The method involves phase separation and requires only aqueous solution, eliminating the need for organic solvents. The aqueous phase separation involves contacting a polymer solution comprising a trigger-responsive polymer with an aqueous coagulation solution in which the trigger-responsive polymer is not soluble.

公开(公告)号：US20210394179A1

公开(公告)日：2021-12-23

申请号：US17287279

申请日：2019-10-25

Applicant: Universiteit Twente

Inventor： Séverine Le Gac ,  Jeroen Christianus Hermanus Leijten ,  Carlo Alberto Paggi ,  Bastien Venzac

IPC: B01L3/00

Abstract: The invention provides a system comprising a microfluidic device for providing a mechanical stimulation to a material, the microfluidic device comprising a hosting chamber, a pressure array, and an elastic membrane, wherein the hosting chamber is configured for hosting the material, wherein the membrane is arranged between the pressure array and the hosting chamber, wherein the pressure array comprises a plurality of pressure chambers configured to independently provide a pressure to the membrane, wherein the pressure array comprises two adjacent pressure chambers sharing a chamber separator, wherein the membrane is configurable at a plurality of distances from the chamber separator based on pressures provided to the membrane by the two adjacent pressure chambers.