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公开(公告)号：KR1020100116065A
公开(公告)日：2010-10-29
申请号：KR1020090034794
申请日：2009-04-21
Applicant: (주)아모레퍼시픽
CPC classification number: A61Q19/00 , A61K8/022 , A61K8/97 , A61K2800/28 , A61Q1/02
Abstract: PURPOSE: A cosmetic composition containing Panax ginseng C.A. Meyer powder is provided to ensure scrub effect and to promote blood circulation on the face. CONSTITUTION: A cosmetic composition contains Panax ginseng C.A. Meyer powder. The size of Panax ginseng C.A. Meyer powder is 150um to 450 um. The cosmetic composition is used in the form of toner, emulsion, essence, cleansing cream, BB cream, foundation, or pack.
Abstract translation: 目的：含有人参C.A.的化妆品。 提供梅耶粉以确保洗刷效果并促进脸部血液循环。 构成：化妆品组合物含有人参C.A. 梅耶粉。 人参C.A.的大小 梅耶粉是150um到450um。 化妆品组合物以调色剂，乳液，精华，清洁霜，BB霜，粉底或包装的形式使用。
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公开(公告)号：KR1020100098258A
公开(公告)日：2010-09-06
申请号：KR1020090033750
申请日：2009-04-17
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: An external use skin composition containing pine root extract is provided to remove free radical, to protect cellular membrane damage, and to suppress reactive oxygen species(ROS). CONSTITUTION: An external use skin composition contains pine root extract. The composition is used for anti-aging, and cell protection by promoting HSP70 generation. The external use skin composition contains 0.001-99 weight% of pine root extract based on total weight. The composition further contains cosmetically and dermatologically acceptable medium and/or substrate. The composition is used in the form of solution, gel, solid, emulsion, suspension, microemulsion, microcapsule, cream, skin, lotion, or spray. The composition is used for anti-aging and skin regeneration.
Abstract translation: 目的：提供含有松果提取物的外用皮肤组合物，以去除自由基，保护细胞膜损伤和抑制活性氧（ROS）。 构成：外用皮肤组合物含有松果提取物。 该组合物用于促进HSP70产生的抗衰老和细胞保护。 外用皮肤组合物含有0.001-99重量％的松根提取物，基于总重量。 组合物还含有美容和皮肤病学可接受的培养基和/或底物。 该组合物以溶液，凝胶，固体，乳液，悬浮液，微乳液，微胶囊，霜剂，皮肤，洗剂或喷雾剂的形式使用。 该组合物用于抗衰老和皮肤再生。
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公开(公告)号：KR1020100064451A
公开(公告)日：2010-06-15
申请号：KR1020080122893
申请日：2008-12-05
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A cosmetic composition containing stabilized leontopodic acid is provided to suppress collagenase expression and collagen synthesis, and to ensure anti-wrinkle. CONSTITUTION: A cosmetic composition for anti-wrinkle contains 0.00001-10 weight% of leontopodic acid of chemical formula 1 as an active ingredient. The leontopodic acid is isolated from Leontopodium alpinum using hydrous or anhydrous low alcohol, water, or acetone and by extracting again with ethyl acetate, diethylether, benzene, chloroform, or hexane.
Abstract translation: 目的：提供含有稳定性leonododic酸的化妆品组合物，以抑制胶原酶表达和胶原合成，并确保抗皱。 构成：抗皱化妆品组合物含有0.00001-10重量％的作为活性成分的化学式1的十二酸。 使用含水或无水低级醇，水或丙酮从利钠杆菌中分离出leonododic酸，并再次用乙酸乙酯，乙醚，苯，氯仿或己烷萃取。
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84.发明公开꽃가루, 집먼지 진드기 또는 황사에 의한 피부 유해반응을 스크리닝하는 방법 및 이를 조절하는 피부 외용제 조성물 有权用于通过花粉，房尘螨或黄锈砂筛选皮肤有害反应的方法，以及用于控制反应的皮肤外部应用的组合物
公开(公告)号：KR1020100060752A
公开(公告)日：2010-06-07
申请号：KR1020080119483
申请日：2008-11-28
Applicant: (주)아모레퍼시픽
CPC classification number: G01N33/5023 , A61K36/58 , C12Q1/6844 , C12Q2600/136 , G01N33/15
Abstract: PURPOSE: A method for screening a material which relieves skin irritation by environmental harmful factor is provided to manufacture an external use formulation and to detoxify. CONSTITUTION: A method for screening a material which relieves skin irritation by environmental harmful factor comprises: a step of treating candidates which regulates intracellular factor in vitro; a step of treating the environmental harmful factor to test cells to induce overexpression of the factor; and a step of measuring expression level. The test cells are keratinocytes. The environmental harmful factor is pollen or yellow sand. The overexpressed factor is interleukin 6 or 8, GSTT1, NQ01, or hBD3. The screened material is Melia azedarach L. var. japonica Makino or Tussilago farfara L. extract.
Abstract translation: 目的：提供一种用于筛选由环境有害因素减轻皮肤刺激的物质的方法，以制造外用制剂和解毒。 构成：通过环境有害因子筛选缓解皮肤刺激的材料的方法包括：处理体外调节细胞因子的候选物的步骤; 治疗环境有害因素以测试细胞以诱导因子过表达的步骤; 以及测量表达水平的步骤。 测试细胞是角质形成细胞。 环境有害因素是花粉或黄沙。 过表达因子是白细胞介素6或8，GSTT1，NQ01或hBD3。 筛选的材料是Melia azedarach L. var。 粳稻或东方龙草L.提取物。
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公开(公告)号：KR1020100059305A
公开(公告)日：2010-06-04
申请号：KR1020080118035
申请日：2008-11-26
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A skin composition for external use containing Broussonetiae Fructus extract is provided to ensure skin barrier strengthening and skin moisturization and to be used in cosmetic products and in the medicinal field. CONSTITUTION: A composition for external use contains Broussonetiae Fructus extract as an active ingredient. The Broussonetiae Fructus extract enhances PPARs(peroxisome proliferator-activated receptors), fillatrin, trasglutaminase 1(TGase 1), or an hyaluronic acid synthase 1(HAS2) gene expression. The composition is used in the form of a lotion, eye cream, nutrition cream, massage cream, cleansing cream, cleansing foam, cleansing water, powder, essence, pack, or ointment.
Abstract translation: 目的：提供含有Broussonetiae Fructus提取物的外用皮肤组合物，以确保皮肤屏障增强和皮肤保湿，并用于化妆品和药用领域。 构成：外用组合物含有布鲁氏酵母提取物作为活性成分。 Broussonetiae Fructus提取物增强PPARs（过氧化物酶体增殖物激活受体），fillatrin，trasglutaminase 1（TGase 1）或透明质酸合酶1（HAS2）基因表达。 该组合物以洗剂，眼霜，营养霜，按摩霜，清洁霜，清洁泡沫，清洁水，粉末，精华，包装或软膏的形式使用。
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Patent Agency Ranking86.发明公开황사에 의한 피부 자극 인자, 피부 자극 유도 방법, 상기 피부 자극 인자를 억제시키고 피부 자극을 완화시키는 물질을 스크리닝하는 방법 및 상기 방법으로 스크리닝된 물질을 함유하는 피부 외용제 조성물 有权皮肤刺激因子，含有黄皮质，以及诱导皮肤刺激和筛选抑制皮肤刺激因子的材料的方法，评估杀菌剂中的皮肤刺激，以及包含通过该方法筛选的材料的皮肤外部应用的组合物
公开(公告)号：KR1020100059042A
公开(公告)日：2010-06-04
申请号：KR1020080117680
申请日：2008-11-25
Applicant: (주)아모레퍼시픽 , 고려대학교 산학협력단
IPC: A61K31/195 , C12Q1/68 , A61K31/352
CPC classification number: A61K31/195 , A61K31/352 , C12Q1/6844 , C12Q2600/136 , C12Q2600/158 , G01N33/15 , G01N33/5023
Abstract: PURPOSE: A method for screening a material which induces skin irritation by yellow dust is provided to reduce skin irritative factor expression and to reduce skin irritation by yellow dust. CONSTITUTION: A method for screening a material which induces skin irritation by yellow dust comprises: a step of treating yellow dust to keratinocytes; and a step of screening a gene of which expression level is significantly changed comparing with the expression of normal keratinocytes through RT-PCR. The material which induces skin irritation by yellow dust is AhR or CYP. A method for screening a material which relieves skin irritation by yellow dust comprises: a step of treating yellow dust to test cells to induce overexpression of an irritative factor; a step of treating a candidate material to the overexpressed cells; a step of measuring expression level of the irritative factor by RT-PCR. The material which relieves skin irritation by yellow dust is Trichosanthis semen. An external use skin composition for relieving skin irritation contains 0.001-1 weight% of Trichosanthis semen.
Abstract translation: 目的：提供一种筛选黄色粉尘引起皮肤刺激的材料的方法，以减少皮肤刺激因子的表达，并减少黄色粉尘的皮肤刺激。 构成：用于筛选黄色粉尘引起皮肤刺激的材料的方法包括：将黄色粉末处理成角质形成细胞的步骤; 与通过RT-PCR的正常角质化细胞的表达相比，筛选其表达水平显着变化的基因的步骤。 黄色粉尘引起皮肤刺激的物质是AhR或CYP。 用于筛选减轻黄色粉尘对皮肤刺激的材料的方法包括：处理黄色粉尘以测试细胞以诱导刺激性因子的过度表达的步骤; 将候选材料处理到过表达细胞的步骤; 通过RT-PCR测定刺激因子的表达水平的步骤。 减轻黄色粉尘的皮肤刺激性的物质是Trichosanthis精液。 用于缓解皮肤刺激的外用皮肤组合物含有0.001-1重量％的Trichosanthis精液。
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87.发明公开백화사설초, 대황, 닥나무 추출물을 함유하는 미백용 피부외용제 조성물 有权含有OLDENLANDIA DIFFUSA WILLD，RHEUM UNDULATUM和BROUSSONETIA KAZINOKI EXTRACT的外用皮肤应用的白色组合物
公开(公告)号：KR1020100059033A
公开(公告)日：2010-06-04
申请号：KR1020080117660
申请日：2008-11-25
Applicant: (주)아모레퍼시픽
CPC classification number: A61Q19/02 , A61K8/97 , A61K2800/782
Abstract: PURPOSE: An external use skin composition for skin whitening containing natural products extract is provided to ensure skin whitening effect and melanogenesis suppression with stability to the skin. CONSTITUTION: An external use skin composition contains extract of Oldenlandia Diffusa Willd, Rheum undulatum LINNE, and Broussonetia kazinoki Sieb as an active ingredient. The extract of Oldenlandia Diffusa Willd, Rheum undulatum LINNE, and Broussonetia kazinoki Sieb is mixed in a weight ratio of 1-4:1-4:1-4.
Abstract translation: 目的：提供含有天然产物提取物的皮肤美白外用皮肤组合物，以确保皮肤美白效果和对皮肤稳定的黑素生成抑制作用。 构成：外用皮肤组合物含有Oldenlandia Diffusa Willd，Rheum undulatum LINNE和Broussonetia kazinoki Sieb的提取物作为活性成分。 将Oldenlandia Diffusa Willd，Rheum undulatum LINNE和Broussonetia kazinoki Sieb的提取物以1-4：1-4：1-4的重量比混合。
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88.发明公开사삼, 고본 및 생약 추출물을 포함하는 것을 특징으로 하는화장료 조성물 有权含有ADENOPHORA TRIPHYLLA VAR的提取物的化妆品组合物。 JAPONICA HARA，ANGELICA TENUISSIMA和CRUDE DRUGS
公开(公告)号：KR1020100056200A
公开(公告)日：2010-05-27
申请号：KR1020080115260
申请日：2008-11-19
Applicant: (주)아모레퍼시픽
CPC classification number: A61K8/97 , A61K2800/522 , A61Q19/00
Abstract: PURPOSE: A cosmetic composition containing Adenophora triphylla var. japonica Hara, Angelica tenuissima Nakai, Ligusticum sinense Oliv, and herb extract is provided to ensure anti-oxidation and moisturization effects. CONSTITUTION: A cosmetic composition contains Adenophora triphylla var. japonica Hara, Angelica tenuissima Nakai, Ligusticum sinense Oliv, and herb extract as an active ingredient. The composition additionally contains Lycium chinense Mill. or Paeonia suffruticosa Andrews extract. The composition is obtained through a Milja method. The Milja method comprises: a step of diluting honey in warm water and spraying the honey water into medicinal herb materials; and a step of roasting the herb materials at 100-180°C for 10 minutes to one hour.
Abstract translation: 目的：含有Adenophora triphylla var。 粳稻，当归，中药，草药提取物，以确保抗氧化和保湿效果。 构成：化妆品组合物含有三叶草（Adenophora triphylla var。 粳稻，当归，中药，草药提取物作为活性成分。 该组合物还含有枸杞子。 或芍药安德鲁斯提取物。 通过Milja方法获得组合物。 Milja方法包括：将蜂蜜在温水中稀释并将蜂蜜水喷洒到药材中的步骤; 并将草本材料在100-180℃下烘烤10分钟至1小时。
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89.发明公开
公开(公告)号：KR1020100055734A
公开(公告)日：2010-05-27
申请号：KR1020080114595
申请日：2008-11-18
Applicant: (주)아모레퍼시픽
IPC: A61K31/366 , A61K31/352 , A61P17/00
Abstract: 본발명은 7,3',4'-트리하이드록시이소플라본을유효성분으로함유하는피부장벽강화용또는보습용피부외용제조성물에관한것으로, 보다상세하게는오르토-디하이드록시이소플라본인 7,3',4'-트리하이드록시이소플라본을함유함으로써생체내 퍼옥시좀증식체활성화수용체알파(PPAR α)를활성화시켜그 발현을증가시킬뿐만아니라, 필라그린유전자, 트랜스글루타미네이즈 1 유전자및 히알루론산합성효소 2 유전자의발현을증가시켜피부각질세포의분화를유도하고피부장벽을강화하며피부수분함량을증가시키는피부외용제조성물에관한것이다.
Abstract translation: 目的：提供含有7,3'，4'-三羟基异黄酮的外用皮肤组合物，以诱导角质形成细胞的分化并增强皮肤的保湿作用。 构成：用于保湿和增强皮肤屏障的外用皮肤组合物含有0.001-10重量％的作为活性成分的7,3'，4'-三羟基异黄酮。 7,3'，4'-三羟基异黄酮激活过氧化物酶体增殖物激活受体（PPARs）。 7,3'，4'-三羟基异黄酮增加了丝胶蛋白，转谷氨酰胺酶1和透明质酸合成酶2基因的表达。 该组合物以收敛剂，眼霜，按摩膏，清洁霜，清洁泡沫，清洁水，粉末，精华，包装或软膏的形式使用。
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公开(公告)号：KR1020100015042A
公开(公告)日：2010-02-12
申请号：KR1020080075927
申请日：2008-08-04
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A cosmetic composition containing sea algae fiber as an active ingredient is provided to remove harmful materials by adsorbing and transfer natural nutrition ingredients. CONSTITUTION: A cosmetic composition contains 0.01-20 weight% of sea algae fiber as an active ingredient. The sea algae fiber is obtained from green laver, chlorella, cosmarium, closterium, hearing and green laver including gelidium amansii, gracilaria, the nose soil. The supino island, gigartina, laver, injury, the glue plant, pterocladia, acanthopeltis japonica, gracilaria, visible gelidium jelly, ceramium kondoi, brown seaweed, laminaria japonica, gulfweed, ecklonia cava, and ecklonia stolonifera. The cosmetic composition is used in the form of skin softener, massage cream, lotion, ointment, gel, lipstick, mascara, cleansing oil, cleansing cream, spray, powder, foundation, eye shadow, foam cleanser or shampoo.
Abstract translation: 目的：提供含有海藻纤维作为活性成分的化妆品组合物，通过吸收和转移天然营养成分来除去有害物质。 构成：化妆品组合物含有0.01-20重量％的海藻纤维作为活性成分。 海藻纤维由绿色紫菜，小球藻，海藻，ium ium，听觉和绿色紫菜获得，包括枸杞子，江ia，鼻土。 上野岛，吉格加特，紫菜，伤害，胶水植物，蕨类植物，j ica，江楂，可见的枸杞，檀香，棕色海藻，aria粳，草甘膦，ecklonia cava和ecklonia stolonifera。 化妆品组合物以皮肤柔软剂，按摩霜，洗剂，软膏，凝胶，口红，睫毛膏，清洁油，清洁霜，喷雾剂，粉剂，粉底，眼影，泡沫清洁剂或洗发剂的形式使用。
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