Abstract:
The prevention relates to a composition for the prevention, alleviation or treatment of a Th2-mediated immune disease, the composition including, as an active ingredient, an extract of at least one natural substance selected from the group consisting of Zea mays, Boswellia carterii and Morus alba. According to the present invention, the extract of a natural substance has inhibitory effects against the generation of IL-4 and the degranulation of mast cells, and thus can prevent, alleviate or treat a Th2-mediated immune disease.
Abstract:
The prevention relates to a composition for the prevention, alleviation or treatment of a Th2-mediated immune disease, which comprises, as an active ingredient, an extract of at least one natural substance selected from the group consisting of Zea mays, Boswellia carterii and Morus alba. According to the present invention, the extract of a natural substance has inhibitory effects against the generation of IL-4 and the degranulation of mast cells and thus can prevent, alleviate or treat a Th2-mediated immune disease.
Abstract:
The present invention relates to a composition comprising Poria cocos extract as an active ingredient for preventing, alleviating, or treating a Th1-mediated immune diseases or Th2-mediated immune diseases. According to the present invention, the Poria cocos extract has activities for inhibiting production of IL-4 and IL-10, inhibiting degranulation of mast cells, inducing differentiation to Treg cells, and stabilizing Treg cells, thereby preventing, alleviating, or treating the Th1-mediated immune diseases or the Th2-mediated immune diseases.
Abstract:
The present invention relates to a composition comprising Nardostachys jatamanse extract as an active ingredient for preventing, alleviating, or treating a Th1-mediated immune disease or a Th2-mediated immune disease. According to the present invention, the Nardostachys jatamanse extract has IL-4 inhibition, degranulation inhibition of mast cells, and differentiation to Treg cells inducing activities, thereby capable of preventing, alleviating, or treating the Th1-mediated immune disease or the Th2-mediated immune disease.
Abstract:
PURPOSE: A systemic immunity or intestinal immunity adjuvant containing a Cheonggukjang extract as an active ingredient is provided to induce Th1 and Th2 responses against parenteral infectious pathogenic microorganisms, virus, cancer antigens, and general antigens as well as oral infectious pathogenic microorganisms during oral administration and to effectively produce a specific antibody. CONSTITUTION: A systemic immunity or intestinal immunity adjuvant contains a Cheonggukjang extract as an active ingredient. The Cheonggukjang extract contains an ethanol soluble ingredient which is prepared using ethanol. The ethanol is 50-99 % ethanol. The Cheonggukjang extract does not contain poly-gamma-glutamic acid (PGA) and levan. Cheonggukjang is prepared using Bacillus amyloliquefaciens. [Reference numerals] (AA,DD) Water extract; (BB) Bean; (CC,FF) 70%EtOH extract; (EE) Cheonggukjang