公开(公告)号：DE3505150A1

公开(公告)日：1986-08-21

申请号：DE3505150

申请日：1985-02-15

Applicant: BASF AG

Inventor： PFAFF KLAUS-PETER DR ,  PAUST JOACHIM DR ,  HARTMANN HORST

IPC: C07H1/00 ,  B01J31/00 ,  C07B61/00 ,  C07H9/04

Abstract: Sugar ketals are prepared by reacting a sugar with a ketone in the presence of an acid catalyst by a process in which A. a molecular boron trifluoride compound or trifluoromethanesulfonic acid is used in an amount of only from 0.01 to 10% by weight, based on the sugar used, B. up to a 30-fold molar excess of the ketone is used and C. the water formed during the reaction is removed continuously from the reaction mixture. In a particularly advantageous embodiment of the process, the boron trifluoride is used in the form of boron trifluoride etherate and, when the reaction is complete, this compound or the trifluoromethanesulfonic acid is rendered ineffective under non-aqueous conditions, after which the ketone is evaporated off and the reaction mixture is then subjected to fractional distillation. The process is particularly important for the reaction of L-sorbose with acetone to obtain 2,3:4,6-di-O-isopropylidene-L-sorbofuranose, which is required for the synthesis of ascorbic acid.

公开(公告)号：DE3360305D1

公开(公告)日：1985-07-25

申请号：DE3360305

申请日：1983-11-24

Applicant: BASF AG

Inventor： SCHMIEDER KLAUS DR ,  PAUST JOACHIM DR ,  FISCHER ROLF DR ,  WEITZ HANS-MARTIN DR

IPC: C07C67/293 ,  C07C67/02 ,  C07C67/343 ,  C07C69/025 ,  C07C69/16 ,  C07C69/73 ,  C07C69/732 ,  C07C403/00 ,  C07D319/06 ,  C07C175/00

Abstract: omega , omega -Diacyloxy-2,6-dimethyl-octatrienoates and -octatrienals, as novel bifunctional asymmetric C10 building blocks for terpene syntheses, which possess a formyl or alkoxycarbonyl group at one chain end and 2 geminal acyloxy groups at the other, and a process for their preparation from readily obtainable industrial C5 building blocks and their use for the synthesis of terpene compounds by carbonyl olefination under conventional conditions.

公开(公告)号：DE3360032D1

公开(公告)日：1985-01-31

申请号：DE3360032

申请日：1983-03-12

Applicant: BASF AG

Inventor： FISCHER ROLF HARTMUTH DR ,  WEITZ HANS MARTIN DR ,  PAUST JOACHIM DR

IPC: C07C67/293 ,  C07C69/16 ,  C09F5/08 ,  C09F7/10 ,  C11C3/00 ,  C11C3/02

Abstract: 2-alkyl-4,4-diacyloxybut-2-enals of the formula I where R1 is alkyl and R2 and R3 are each hydrogen or an aliphatic, cycloaliphatic or aromatic radical, are prepared by a process wherein a 2-alkyl-2,4-diacyloxybut-3-enal of the formula II is treated with an aliphatic carboxylic acid.

公开(公告)号：DE3261458D1

公开(公告)日：1985-01-17

申请号：DE3261458

申请日：1982-06-19

Applicant: BASF AG

Inventor： FISCHER ROLF DR ,  WEITZ HANS-MARTIN DR ,  PAUST JOACHIM DR

IPC: C07C69/007 ,  C07C67/00 ,  C07C67/29 ,  C07C67/297 ,  C07C69/025 ,  C07C69/145 ,  C07C69/16

Abstract: 2-Alkyl-4,4-diacyloxybut-2-enals of the formula I where R1 is alkyl and R2 and R3 are each hydrogen or an aliphatic, cycloaliphatic or aromatic radical, are prepared by a process in which a 2-alkyl-1,4-diacyloxybuta-1,3-diene of the formula II is reacted with oxygen or an oxygen donor, in the presence of a carboxylic acid of the formula R3-COOH III.

公开(公告)号：DE3244272A1

公开(公告)日：1984-05-30

申请号：DE3244272

申请日：1982-11-30

Applicant: BASF AG

Inventor： SCHMIEDER KLAUS DR ,  PAUST JOACHIM DR ,  FISCHER ROLF DR ,  WEITZ HANS-MARTIN DR

IPC: C07C67/293 ,  C07C67/02 ,  C07C67/343 ,  C07C69/025 ,  C07C69/16 ,  C07C69/73 ,  C07C69/732 ,  C07C403/00 ,  C07D319/06

Abstract: omega , omega -Diacyloxy-2,6-dimethyl-octatrienoates and -octatrienals, as novel bifunctional asymmetric C10 building blocks for terpene syntheses, which possess a formyl or alkoxycarbonyl group at one chain end and 2 geminal acyloxy groups at the other, and a process for their preparation from readily obtainable industrial C5 building blocks and their use for the synthesis of terpene compounds by carbonyl olefination under conventional conditions.

公开(公告)号：DE2963424D1

公开(公告)日：1982-09-16

申请号：DE2963424

申请日：1979-09-28

Applicant: BASF AG

Inventor： PAUST JOACHIM DR ,  NUERRENBACH AXEL DR ,  KOENIG HORST DR

IPC: A61K31/165 ,  A61K31/16 ,  A61P35/00 ,  C07C67/00 ,  C07C401/00 ,  C07C403/00 ,  C07C403/20 ,  C07D309/12 ,  C07D317/28 ,  C07D317/30 ,  C07C175/00

公开(公告)号：CH626082A5

公开(公告)日：1981-10-30

申请号：CH190577

申请日：1977-02-16

Applicant: BASF AG

Inventor： GRAFEN PAUL DR ,  KROESCHE HENNING DR ,  SCHULZ BERNHARD DR ,  PAUST JOACHIM DR ,  PFOHL SIGBERG DR

IPC: C07D311/72

公开(公告)号：CH622233A5

公开(公告)日：1981-03-31

申请号：CH1277276

申请日：1976-10-08

Applicant: BASF AG

Inventor： HOFFMANN WERNER DR ,  MUELLER NORBERT DR ,  PAUST JOACHIM DR

IPC: C07B57/00 ,  C07B31/00 ,  C07C67/00 ,  C07C209/00 ,  C07C209/26 ,  C07C211/38 ,  C07D307/32 ,  C07B19/00 ,  C07C87/40

公开(公告)号：CH619211A5

公开(公告)日：1980-09-15

申请号：CH1559775

申请日：1975-12-01

Applicant: BASF AG

Inventor： SCHOLZ HERBERT DR ,  KOENIG HORST DR ,  PAUST JOACHIM DR ,  WIERSDORFF WALTER-WIELANT DR ,  BLECHSCHMIDT WOLFGANG DR ,  KRETZSCHMAR ROLF DR ,  CHRISTOPHERS ENNO DR

IPC: A61K8/67 ,  A61K31/16 ,  A61K31/20 ,  A61K31/23 ,  A61Q5/00 ,  A61Q19/00 ,  C07C403/00 ,  C07D295/185 ,  C07C175/00

公开(公告)号：CH617651A5

公开(公告)日：1980-06-13

申请号：CH104475

申请日：1975-01-29

Applicant: BASF AG

Inventor： HOFFMANN WERNER DR ,  HIMMELE WALTER DR ,  PAUST JOACHIM DR ,  FRAUNBERG KARL VON DR ,  SIEGEL HARDO DR ,  PFOHL SIGBERG DR

IPC: C07C31/137 ,  C07B61/00 ,  C07C27/00 ,  C07C29/14 ,  C07C29/141 ,  C07C41/00 ,  C07C43/303 ,  C07C45/00 ,  C07C45/50 ,  C07C47/347 ,  C07C47/45 ,  C07C51/00 ,  C07C61/13 ,  C07C67/00 ,  C07C69/753 ,  C07C209/00 ,  C07C209/26 ,  C07C209/28 ,  C07C209/52 ,  C07C209/88 ,  C07C211/03 ,  C07C211/17 ,  C07C211/19 ,  C07C211/27 ,  C07C211/38 ,  C07C211/44 ,  C07C213/08 ,  C07C231/00 ,  C07C231/02 ,  C07C233/55 ,  C07D295/02 ,  C07D295/03 ,  C07D295/22 ,  C07C43/305 ,  C07B19/00

Abstract: Pinanes substituted by a group X in the 3-position which group is formyl, or its alkyl-acetals or alkyl-hemiacetals, carboxylic acid, carboxylic acid chloride, carboxylic acid amide, hydroxymethyl or aminomethyl substituted in a specific manner at the nitrogen, the optical isomers of these compounds and a process for their manufacture by hydroformylation of alpha -pinene in the presence of rhodium catalysts, and conversion of the 3-formylpinane first produced into the above derivatives by conventional methods.