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公开(公告)号:SI9520080B
公开(公告)日:2003-02-28
申请号:SI9520080
申请日:1995-07-14
Applicant: BASF AG
Inventor: HELLENDAHL BEATE , LANSKY ANNEGRET , MUNSCHAUER RAINER , BIALOJAN SIEGFRIED , UNGER LILIANE , TESCHENDORF HANS-JUERGEN , WICKE KARSTEN , DRESCHER KARLA
IPC: C07D239/26 , A61K31/505 , A61K31/506 , A61P25/16 , A61P25/24 , A61P25/26 , C07D239/38 , C07D239/46 , C07D239/56 , C07D239/60 , C07D401/00 , C07D401/12 , A61K31/305
Abstract: The present invention relates to the use of pyrimidine compounds of the following formula:wherein R1, R2, R3, A, B and Ar have the meanings indicated in the description. The compounds according to the invention have a high affinity for the dopamine D3 receptor and can therefore be used to treat disorders which respond to dopamine D3 ligands.
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公开(公告)号:PT772603E
公开(公告)日:2002-11-29
申请号:PT95926898
申请日:1995-07-14
Applicant: BASF AG
Inventor: HELLENDAHL BEATE , UNGER LILIANE , TESCHENDORF HANS-JUERGEN , MUNSCHAUER RAINER , LANSKY ANNEGRET , BIALOJAN SIEGFRIED , WICKE KARSTEN , DRESCHER KARLA
IPC: C07D239/26 , A61K31/505 , A61K31/506 , A61P25/16 , A61P25/24 , A61P25/26 , C07D239/38 , C07D239/46 , C07D239/56 , C07D239/60 , C07D401/00 , C07D401/12
Abstract: The present invention relates to the use of pyrimidine compounds of the following formula:wherein R1, R2, R3, A, B and Ar have the meanings indicated in the description. The compounds according to the invention have a high affinity for the dopamine D3 receptor and can therefore be used to treat disorders which respond to dopamine D3 ligands.
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公开(公告)号:SI1104419T1
公开(公告)日:2002-10-31
申请号:SI9930058
申请日:1999-07-20
Applicant: BASF AG
Inventor: STEINER GERD , HOEGER THOMAS , UNGER LILIANE , TESCHENDORF HANS-JUERGEN , JUCHELKA FRIEDER
IPC: A61K31/425 , C07D417/06
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84.
公开(公告)号:BG63633B1
公开(公告)日:2002-07-31
申请号:BG10122097
申请日:1997-02-12
Applicant: BASF AG
Inventor: STEINER GERD , MUNSCHAUER RAINER , HOEGER THOMAS , UNGER LILIANE , TESCHENDORF HANS-JUERGEN
IPC: C07D401/06 , A61K31/40 , A61K31/415 , A61K31/47 , A61K31/505 , A61P25/18 , A61P43/00 , C07D403/06 , C07D471/04 , C07D513/04
Abstract: The invention relates to compounds of formula in which R1, R2, A, X, Y and Z have meanings given in the description, as well as to the method for their preparation. The new compounds are applicable in the human medicine. 4 claims
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公开(公告)号:DE59901563D1
公开(公告)日:2002-07-04
申请号:DE59901563
申请日:1999-07-20
Applicant: BASF AG
Inventor: STEINER GERD , HOEGER THOMAS , UNGER LILIANE , TESCHENDORF HANS-JUERGEN , JUCHELKA FRIEDER
IPC: A61K31/425 , A61K31/428 , A61P25/00 , C07D417/06
Abstract: Compounds of the formula I:in which R1, R2, R3 and R4 have the meanings stated in the description, are described.The novel compounds are suitable for controlling diseases.
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公开(公告)号:HRP20010181A2
公开(公告)日:2002-04-30
申请号:HRP20010181
申请日:2001-03-12
Applicant: BASF AG
Inventor: STEINER GERD , HOEGER THOMAS , UNGER LILIANE , TESCHENDORF HANS-JUERGEN , JUCHELKA FRIEDER
IPC: A61K31/4184 , A61P25/20 , A61P25/24 , A61P25/30 , C07D403/06
Abstract: The invention relates to compounds of formula (1), wherein R , R and R have the meaning cited in the description. The novel substances are suitable for use in disease control.
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公开(公告)号:HRP20010180A2
公开(公告)日:2002-04-30
申请号:HRP20010180
申请日:2001-03-12
Applicant: BASF AG
Inventor: STEINER GERD , HOEGER THOMAS , UNGER LILIANE , TESCHENDORF HANS-JUERGEN , JUCHELKA FRIEDER
IPC: A61K31/425 , A61K31/428 , A61P25/00 , C07D417/06
Abstract: Compounds of the formula I:in which R1, R2, R3 and R4 have the meanings stated in the description, are described.The novel compounds are suitable for controlling diseases.
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公开(公告)号:DE59803292D1
公开(公告)日:2002-04-11
申请号:DE59803292
申请日:1998-07-03
Applicant: BASF AG
Inventor: STARCK DOROTHEA , BLANK STEFAN , TREIBER HANS-JOERG , UNGER LILIANE , NEUMANN-SCHULTZ BARBARA , LE BRIS THEOPHILE-MARIE , TESCHENDORF HANS-JUERGEN , WICKE KARSTEN
IPC: A61K31/33 , A61K31/41 , A61K31/4196 , A61K31/454 , A61K31/506 , A61K31/53 , A61K31/551 , A61P25/00 , A61P25/16 , A61P25/18 , A61P25/22 , A61P25/24 , A61P43/00 , C07D249/08 , C07D249/12 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14
Abstract: Triazole compounds of the following formula:where Ar1, A, B and Ar2 have the meanings given in the description, possess a high affinity for the dopamine D3 receptor and can therefore be used for treating diseases which respond to dopamine D3 ligands.
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公开(公告)号:BG63487B1
公开(公告)日:2002-03-29
申请号:BG10111297
申请日:1997-01-06
Applicant: BASF AG
Inventor: HELLENDAHL BEATE , LANSKY ANNEGRET , RENDENBACH-MUELLER BEATRICE , BACH ALFRED , UNGER LILIANE , TESCHENDORF HANS-JUERGEN , WICKE CARSTEN
IPC: C07D233/84 , A61K31/33 , A61K31/415 , A61K31/44 , A61K31/4402 , A61K31/4406 , A61K31/4409 , A61K31/4418 , A61K31/4425 , A61K31/445 , A61K31/495 , A61K31/496 , A61P25/18 , A61P25/20 , A61P25/24 , A61P25/26 , C07D213/56 , C07D213/64 , C07D213/65 , C07D213/70 , C07D213/73 , C07D213/79 , C07D213/81 , C07D233/90 , C07D307/79 , C07D333/24 , C07D333/28 , C07D333/38 , C07D471/18
Abstract: The invention relates to the use of heterocyclic compounds with the formula Het-A-Ar, where Het, A, B & Ar have the meanings listed in the description. The compounds have high affinity to diopamin-D3-receptors and for this reason are used for the treatment of diseases reacting to dopamin-D3-ligands. 12 claims
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公开(公告)号:UA44903C2
公开(公告)日:2002-03-15
申请号:UA97030904
申请日:1995-07-21
Applicant: BASF AG
Inventor: MUNSCHAUER RAINER , UNGER LILIANE , TESCHENDORF HANS-JUERGEN
IPC: C07D401/06 , A61K31/40 , A61K31/415 , A61K31/47 , A61K31/505 , A61P25/18 , A61P43/00 , C07D403/06 , C07D471/04 , C07D513/04
Abstract: Похідні N-заміщених 3-азабіцикло[3.2.0]гептанівтаїхсоліз фізіологічноприйнятнимикислотами, щомаютьантипсихотичнуактивність. Фармацевтичнакомпозиціяз антипсихотичноюактивністю, якаміститьактивнуречовинунаосновіпохідних N-заміщених 3-азабіцикло[3.2.0]гептанівтафармацевтичноприйнятнийносій.
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