公开(公告)号：SK23099A3

公开(公告)日：1999-08-06

申请号：SK23099

申请日：1997-08-22

Applicant: BASF AG

Inventor： STEINER GERD ,  LUBISCH WILFRIED ,  BACH ALFRED ,  EMLING FRANZ ,  WICKE KARSTEN ,  TESCHENDORF HANS-JURGEN ,  BEHL BERTHOLD ,  KERRRIGAN FRANK ,  CHEETHAM SHARON

IPC: A61K31/435 ,  A61K31/519 ,  A61P25/24 ,  A61P43/00 ,  C07D211/00 ,  C07D239/00 ,  C07D333/00 ,  C07D495/14

Abstract: The invention concerns 3-substituted 3,4,5,6,7,8-hexahydro- pyrid3':4,5]thieno-[2,3-d]pyrimidine derivatives of formula (I), their physiologically acceptable salts and use in the therapy.

公开(公告)号：AU9748498A

公开(公告)日：1999-05-17

申请号：AU9748498

申请日：1998-10-05

Applicant: BASF AG

Inventor： LUBISCH WILFRIED ,  DULLWEBER UTA ,  STARCK DOROTHEA ,  STEINER GERD ,  BACH ALFRED ,  EMLING FRANZ ,  GARCIA-LADONA XAVIER ,  TESCHENDORF HANS-JURGEN ,  WICKE KARSTEN

IPC: A61K31/519 ,  A61P1/00 ,  A61P1/14 ,  A61P3/04 ,  A61P5/00 ,  A61P9/12 ,  A61P15/00 ,  A61P25/00 ,  A61P25/22 ,  A61P25/24 ,  A61P25/28 ,  A61P43/00 ,  C07D471/00 ,  C07D471/04

Abstract: 3-substituted tetrahydropyridopyrimidinone derivatives of the formula (I) wherein the radicals have the meanings given in the Description, to a method for producing said derivatives and, to their use for producing active ingredients for drugs.

公开(公告)号：CA2305258A1

公开(公告)日：1999-05-06

申请号：CA2305258

申请日：1998-10-05

Applicant: BASF AG

Inventor： STEINER GERD ,  STARCK DOROTHEA ,  DULLWEBER UTA ,  BACH ALFRED ,  LUBISCH WILFRIED ,  EMLING FRANZ ,  GARCIA-LADONA XAVIER ,  TESCHENDORF HANS-JURGEN ,  WICKE KARSTEN

IPC: A61K31/519 ,  A61P1/00 ,  A61P1/14 ,  A61P3/04 ,  A61P5/00 ,  A61P9/12 ,  A61P15/00 ,  A61P25/00 ,  A61P25/22 ,  A61P25/24 ,  A61P25/28 ,  A61P43/00 ,  C07D471/00 ,  C07D471/04

Abstract: The invention relates to 3-substituted tetrahydropyridopyrimidinone derivatives of formula (I) wherein the radicals have the meanings given in the Description, to a method for producing said derivatives, and to their use as selective 5HT1B-and 5HT1A antagonists.

公开(公告)号：AU703857B2

公开(公告)日：1999-04-01

申请号：AU3111695

申请日：1995-07-14

Applicant: BASF AG

Inventor： HELLENDAHL BEATE ,  LANSKY ANNEGRET ,  MUNSCHAUER RAINER ,  BIALOJAN SIEGFRIED ,  UNGER LILIANE ,  TESCHENDORF HANS-JURGEN ,  WICKE KARSTEN ,  DRESCHER KARLA

IPC: C07D239/26 ,  A61K31/505 ,  A61K31/506 ,  A61P25/16 ,  A61P25/24 ,  A61P25/26 ,  C07D239/38 ,  C07D239/46 ,  C07D239/56 ,  C07D239/60 ,  C07D401/00 ,  C07D401/12

Abstract: The present invention relates to the use of pyrimidine compounds of the following formula:wherein R1, R2, R3, A, B and Ar have the meanings indicated in the description. The compounds according to the invention have a high affinity for the dopamine D3 receptor and can therefore be used to treat disorders which respond to dopamine D3 ligands.

公开(公告)号：SK94198A3

公开(公告)日：1999-03-10

申请号：SK94198

申请日：1997-01-10

Applicant: BASF AG

Inventor： TREIBER HANS-JORG ,  BLANK STEFAN ,  STARCK DOROTHEA ,  UNGER LILIANE ,  TESCHENDORF HANS-JURGEN ,  WICKE KARSTEN

IPC: A61K31/00 ,  A61K31/40 ,  A61K31/4025 ,  A61K31/41 ,  A61K31/44 ,  A61K31/4427 ,  A61K31/4433 ,  A61K31/4439 ,  C07D243/08 ,  A61K31/505 ,  A61K31/506 ,  A61K31/55 ,  A61K31/551 ,  A61K31/5513 ,  A61P25/18 ,  A61P43/00 ,  C07D213/73 ,  C07D223/04 ,  C07D245/02 ,  C07D401/04 ,  C07D401/14 ,  C07D403/02 ,  C07D403/04 ,  C07D403/06 ,  C07D403/10 ,  C07D403/12 ,  C07D403/14 ,  C07D405/14 ,  C07D409/12 ,  C07D409/14 ,  C07D413/14 ,  C07D417/06 ,  C07D417/12 ,  C07D417/14

Abstract: Aza- and diazacyclohexane and -cyclooctane compounds of the following formula:where Ar1, A, B and Ar2 have the meanings stated in the description have a high affinity for the dopamine D3 receptor and can therefore be used to treat disorders which respond to dopamine D3 ligands.

公开(公告)号：TR9801302T2

公开(公告)日：1998-11-23

申请号：TR9801302

申请日：1997-01-10

Applicant: BASF AG

Inventor： TREIBER HANS-JOERG ,  BLANK STEFAN ,  STARCK DOROTHEA ,  UNGER LILIANE ,  TESCHENDORF HANS-JURGEN ,  WICKE KARSTEN

IPC: C07D243/08 ,  A61K31/00 ,  A61K31/40 ,  A61K31/4025 ,  A61K31/41 ,  A61K31/44 ,  A61K31/4427 ,  A61K31/4433 ,  A61K31/4439 ,  A61K31/505 ,  A61K31/506 ,  A61K31/55 ,  A61K31/551 ,  A61K31/5513 ,  A61P25/18 ,  A61P43/00 ,  C07D213/73 ,  C07D223/04 ,  C07D245/02 ,  C07D401/04 ,  C07D401/14 ,  C07D403/02 ,  C07D403/04 ,  C07D403/06 ,  C07D403/10 ,  C07D403/12 ,  C07D403/14 ,  C07D405/14 ,  C07D409/12 ,  C07D409/14 ,  C07D413/14 ,  C07D417/06 ,  C07D417/12 ,  C07D417/14

CPC classification number: C07D403/04 ,  C07D403/12 ,  C07D403/14 ,  C07D417/14

公开(公告)号：AU699021B2

公开(公告)日：1998-11-19

申请号：AU3116595

申请日：1995-07-22

Applicant: BASF AG

Inventor： STEINER GERD ,  MUNSCHAUER RAINER ,  HOGER THOMAS ,  UNGER LILIANE ,  TESCHENDORF HANS-JURGEN

IPC: C07D409/12 ,  A61K31/40 ,  A61K31/403 ,  A61P25/18 ,  A61P43/00 ,  C07D209/44 ,  C07D209/52 ,  C07D209/90 ,  C07D209/92 ,  C07D403/06

Abstract: PCT No. PCT/EP95/02912 Sec. 371 Date Feb. 3, 1997 Sec. 102(e) Date Feb. 3, 1997 PCT Filed Jul. 22, 1995 PCT Pub. No. WO96/04245 PCT Pub. Date Feb. 15, 1996A compound of the formula in which A, R1 and n have the meanings stated in the description are described. The novel compounds are suitable for controlling diseases.

公开(公告)号：AU696230B2

公开(公告)日：1998-09-03

申请号：AU3116295

申请日：1995-07-21

Applicant: BASF AG

Inventor： STEINER GERD ,  MUNSCHAUER RAINER ,  HOGER THOMAS ,  UNGER LILIANE ,  TESCHENDORF HANS-JURGEN

IPC: C07D401/06 ,  A61K31/40 ,  A61K31/415 ,  A61K31/47 ,  A61K31/505 ,  A61P25/18 ,  A61P43/00 ,  C07D403/06 ,  C07D471/04 ,  C07D513/04

Abstract: PCT No. PCT/EP95/02893 Sec. 371 Date Sep. 18, 1997 Sec. 102(e) Date Sep. 18, 1997 PCT Filed Jul. 21, 1995 PCT Pub. No. WO96/04272 PCT Pub. Date Feb. 15, 1996N-substitued 3-azabicyclo[3.2.0]heptane derivatives of formula (I) in which R1, R2, A, X, Y and Z have the meanings given in the description, their method of preparation and their use as pharmacological agents.

公开(公告)号：HRP940960A2

公开(公告)日：1997-10-31

申请号：HRP940960

申请日：1994-11-29

Applicant: BASF AG

Inventor： STEINER GERD ,  MINSCHAUER RAINER ,  UNGER LILIANE ,  TESCHENDORF HANS-JURGEN ,  HOEGER THOMAS

IPC: C07D401/04 ,  A61K31/40 ,  A61K31/403 ,  A61K31/44 ,  A61K31/4427 ,  A61K31/443 ,  A61K31/4433 ,  A61K31/505 ,  A61P25/00 ,  A61P25/02 ,  A61P25/08 ,  A61P25/18 ,  A61P25/28 ,  A61P43/00 ,  C07D209/02 ,  C07D209/46 ,  C07D209/52 ,  C07D209/90 ,  C07D209/96 ,  C07D403/04 ,  C07D403/06 ,  C07D405/06 ,  C07D409/04 ,  C07D409/06 ,  C07D413/06

Abstract: PCT No. PCT/EP94/03910 Sec. 371 Date Apr. 19, 1996 Sec. 102(e) Date Apr. 19, 1996 PCT Filed Nov. 26, 1994 PCT Pub. No. WO95/15312 PCT Pub. Date Jun. 8, 1995Compounds of the formula I I where the substituents have the meanings given in the description, and their preparation are described. The novel compounds are suitable for the control of diseases.

公开(公告)号：MX9700854A

公开(公告)日：1997-04-30

申请号：MX9700854

申请日：1995-07-22

Applicant: BASF AG

Inventor： STEINER GERD ,  MUNSCHAUER RAINER ,  HOGER THOMAS ,  UNGER LILIANE ,  TESCHENDORF HANS-JURGEN

IPC: A61K31/40 ,  A61K31/403 ,  A61P25/18 ,  A61P43/00 ,  C07D209/44 ,  C07D409/12 ,  C07D209/52 ,  C07D209/90 ,  C07D209/92 ,  C07D403/06

Abstract: Nuevos compuestos que tienen la formula (I), en los cuales A, R1 y n tienen los significados dados en la descripcion, que son utiles para combatir enfermedades.