公开(公告)号：JPH06234626A

公开(公告)日：1994-08-23

申请号：JP2145193

申请日：1993-02-09

Applicant: CANON KK

Inventor： TOMITA YASUKO ,  OYAMA JUNJI ,  NOMOTO TAKESHI ,  MARUYAMA TOMOKO

IPC: A61K9/127 ,  A61K47/30 ,  C07F9/10

Abstract: PURPOSE:To obtain a polymerizable proteoliposome imparted with stability by the introduction of polymerizable functional group and resistant to the deterioration of the acquired function of protein. CONSTITUTION:This polymerizable proteoliposome contains a polymerizable phospholipid of the formula [one or both of R1 and R2 are acyl of the formula R'-CH=CHCH=CHCO (R' is 5-17C alkyl) or one is the above acyl and the other is a saturated or unsaturated 10-22C fatty acid residue] and a protein capable of being supported with the liposome membrane constituted of the polymerizable phospholipid. When bacteriorhodopsin which is a membraneous protein transporting proton with light is used as the protein to be supported, the function of the protein cannot be developed because the proton concentration gradient formed by the light-irradiation of bacteriorhodopsin is not maintained in a state of monomer before polymerization. The function is first developed by polymerization and the development of the function and the extent of developed function of the protein can be controlled by controlling the polymerization degree. The particle size of liposome is also controllable by starting the polymerization when the particle diameter reaches the desired level.

公开(公告)号：JPH0566199A

公开(公告)日：1993-03-19

申请号：JP22896191

申请日：1991-09-09

Applicant: CANON KK

Inventor： NOMOTO TAKESHI ,  TOMITA YASUKO ,  YAMAMOTO NOBUKO ,  KAWAGUCHI MASAHIRO ,  OYAMA JUNJI

IPC: G01N21/33 ,  G01N33/28 ,  G01N33/92

Abstract: PURPOSE:To enable quantitative analysis of fat, especially amphipatic lipid forming an aggregate in an aqueous medium to be easily carried out by treating a sample with a surface active agent in an aqueous medium to prepare a sample-dispersed liquid, and measuring the absorbency of the ultraviolet portion of the sample-dispersed liquid. CONSTITUTION:Lipid is treated with a surface active agent and converted into a micell state in which its qualititative analysis by absorptiometry is possible. An aggregate of amphipatic lipid, e.g. phospholipid is treated with a surface active agent in an aqueous medium so as to form a micell state of the lipid with the surface active agent. A surface active agent which does not absorb the wavelength of an ultraviolet portion to be measured is employed and thereby the absorption of ultraviolet rays in the micelle state of the lipid with the surface active agent occurs only at the lipid and the absorbency depends on the concentration of the lipid. Therefore, the lipid concentration can be detected by measuring the absorbency. Wavelength can be selected somewhere between 230 and 290nm if it is apparent that no material other than the lipid coexists.

公开(公告)号：JPH0564739A

公开(公告)日：1993-03-19

申请号：JP22616891

申请日：1991-09-05

Applicant: CANON KK

Inventor： TOMITA YASUKO ,  NOMOTO TAKESHI ,  OYAMA JUNJI ,  KAWAGUCHI MASAHIRO ,  YAMAMOTO NOBUKO

IPC: A61K9/127 ,  B01J13/02 ,  C08L91/00

Abstract: PURPOSE:To prepare a large amount of a macro-liposome having a diameter of several ten mum or more, especially, several hundred mum under a mild condition by a simple process. CONSTITUTION:An alkali metal salt aqueous solution having a liposome dispersed therein is frozen and melted to be dialyzed to an aqueous solution or buffer solution whose salt concn. is lower than that of the alkali metal salt aqueous solution to obtain a macro-liposome. This macro-liposome is further held under a constant temp. condition with the range of 0-40 deg.C to fuse a plurality of the macro-liposomes to obtain a macro-lyposome having a larger diameter. In the case of a proteoliposome wherein membrane protein is contained in a lipid membrane, the fusion of a liposome is accelerated in the coexistence of membrane protein.

公开(公告)号：JPH03295278A

公开(公告)日：1991-12-26

申请号：JP9649690

申请日：1990-04-13

Applicant: CANON KK

Inventor： OYAMA JUNJI ,  TOMITA YASUKO ,  SAKURANAGA MASANORI

IPC: H01L31/10 ,  H01L49/00

Abstract: PURPOSE:To enable a photoelectric conversion element possessing a high photoelectric conversion power to be offered by a method wherein an electrolytic solution filled into a cell, a film separating a solution, and a means detecting a film potential change or a pH change induced through the intermediary of the film are provided. CONSTITUTION:A violet film extracted from an R1 stock is treated with an interfacial active agent to remove liquid, the chromophore of the violet film is substituted with naphthyl lecithinal using a part of bacteriorhodopsin as photoreceptive protein. 0.1mg/ml of bacteriorhodopsin and soybean phospholipid 8 are reconstituted into a plane film. Furthermore, the plane film containing bacteriorhodopsin is made to adsorb proteoribosome and fused together so as to be coincident with each other in a proton transfer directional property to obtain an ion transmitting film 3. The film 3 is quietly dipped into a microcell filled with 0.1mol/l of KCl solution, and the cell is separated into chambers 1 and 2 to constitute a photoelectric conversion element. pH electrodes 4 and 5 are dipped into the chamber 1 and the chamber 2. Values measured by the pH electrodes are converted into electric signals through pH meters 6, which are sent to microcomputers 9 through an amplifier 7.

公开(公告)号：JPH02247233A

公开(公告)日：1990-10-03

申请号：JP6736589

申请日：1989-03-18

Applicant: CANON KK

Inventor： OYAMA JUNJI ,  SUGANO TSUNEHIRO ,  TOMITA YASUKO ,  SAKURANAGA MASANORI

IPC: G01J1/00 ,  B01D69/00 ,  B01D71/00 ,  C07K14/00 ,  C07K14/195 ,  C07K14/41 ,  C08J5/18 ,  G01N27/327 ,  H01L49/00

Abstract: PURPOSE:To obtain the subject transmission membrane exhibiting selective ion-transmittance by light irradiation, having expanded active wavelength range and useful in an optical information processing industry by supporting a plurality of substance groups having different sensitive wavelength ranges on a lipid membrane. CONSTITUTION:The objective transmission membrane contains (A) two or more kinds of substance groups having different sensitive wavelength ranges and (B) an ionophore in a lipid membrane. Preferably, the component A is a photoreceptive protein or its derivative, especially bacteriorhodopsin or halorhodopsin and the component B is oligopeptide, etc. Furthermore, the component is preferably held in the lipid membrane in an oriented state to uniformize the ion transmission direction.

公开(公告)号：JPH0218474A

公开(公告)日：1990-01-22

申请号：JP16688388

申请日：1988-07-06

Applicant: CANON KK

Inventor： TOMITA YASUKO

IPC: C09D11/00 ,  C09D11/328

Abstract: PURPOSE:To obtain an aimed ink containing a specific compound in the ink composed of a dye and liquid medium, free from occurrence of clogging in the tip of a pen and nozzle of head and suitable for ink jet recording system. CONSTITUTION:The aimed ink containing a compound expressed by the formula (R1-R3 are H, OH or hydrocarbon provided that at least one kind of R1-R3 is >=6C hydrocarbon; R4 and R5 are H or methyl; m and n are 1-40 and m+n is 2-60), preferably at an amount of 2-10wt.% in the ink composed of a dye and liquid medium.

公开(公告)号：JPH01230685A

公开(公告)日：1989-09-14

申请号：JP5629588

申请日：1988-03-11

Applicant: CANON KK

Inventor： TOMITA YASUKO ,  KOIKE SHOJI

IPC: C09D11/00 ,  C09D11/322 ,  C09D11/328

Abstract: PURPOSE:To obtain an ink which, when applied on plain paper as well as on paper for ink jet printing, does not blot and is improved in drying property and permeability, by adding a copolymer of ethylene oxide with propylene oxide to an ink. CONSTITUTION:A compound of the general formula: HO-(C2H4O)a-C3H6O-(C2H4 O)b-H (wherein the sum of a and b is 500 or below, and b may be 0) is added to an ink comprising a pigment and a liquid medium. It is desirable that 0.1-60wt.% said compound is contained in the ink.

公开(公告)号：JPH01215875A

公开(公告)日：1989-08-29

申请号：JP3959888

申请日：1988-02-24

Applicant: CANON KK

Inventor： TOMITA YASUKO ,  KOIKE SHOJI

IPC: C09D11/00 ,  C09D11/16

Abstract: PURPOSE:To obtain an ink having improved characteristics in respect of blotting, dryability, safety in use at offices and homes, and storage stability, by mixing a coloring matter, a liquid medium, and a specified compound. CONSTITUTION:An objective ink is obtained by mixing 0.2-20wt.% coloring matter (e.g., C.I. Food Black 2); a liquid medium (e.g., water); 1-60wt.%, preferably 3-30wt.%, compound of the formula [wherein R1-3 are each H, a 2-12C (un)saturated aiphatic hydrocarbon group, a 3-10C alicyclic hydrocarbon group or a 6-15C aromatic hydrocarbon group, except for the case where all of them are H at the same time]; and, if necessary, a dispersant, a surface active agent, a viscosity modifier, a surface tension modifier, a fluorescent brightener, etc.

公开(公告)号：JPS63162773A

公开(公告)日：1988-07-06

申请号：JP31082586

申请日：1986-12-26

Applicant: CANON KK

Inventor： KOIKE SHOJI ,  TOMITA YASUKO

IPC: B41J2/01 ,  B41M5/00 ,  C09D11/00 ,  C09D11/02

Abstract: PURPOSE:To obtain the title ink which is rapidly fixed on paper and cloths and has excellent fastness, by mixing a coloring matter having limited solubility in water, a water-soluble organic solvent having a specified solvency for this coloring matter and a specified surface tension, and water. CONSTITUTION:An ink containing as its constituents a coloring matter having a solubility in water of 0.1% or lower (at 20 deg.C); a water-soluble organic solvent which can dissolve 3% or more (at 20 deg.C) of this coloring matter and has a surface tension of 45 dyne/cm or less; and water. The coloring matter content, which depends upon the type of liquid medium component, the required characteristics of an ink, etc., is usually 0.2-20wt.% based on the total weight of the ink. Examples of the water-soluble organic solvents to be used, which are required to satisfy the aforementioned conditions, include 1,3-dimethyl-2- imidazoline and triethylene glycol monomethyl ether.

公开(公告)号：JPS63139960A

公开(公告)日：1988-06-11

申请号：JP28706686

申请日：1986-12-02

Applicant: CANON KK

Inventor： KOIKE SHOJI ,  TOMITA YASUKO

IPC: B41J2/01 ,  B41M5/00 ,  C09D11/00

Abstract: PURPOSE:To provide the title ink which has excellent shelf stability and gives prints having good water resistance, by dissolving a soluble sulfur due and an antioxidant in a liquid medium composed of at least water and an org. solvent. CONSTITUTION:0.1-15wt% soluble sulfur dye (e.g., C.I. Soluble Sulfur Yellow 9) or 0.1-15wt% in total of a soluble sulfur dye and a water-soluble anionic dye (e.g., C.I. Direct Yellow 86) in a ratio of 10:1-1:10, 0.1-10wt% antioxidant (e.g., hydroquinone) and optionally, a dispersant, a surfactant, a viscosity modifier, etc. are dissolved in a liquid medium composed of at least water and an inorg. solvent (e.g., methyl alcohol) to obtain an ink for use in ink jet recording, which has a surface tension of 35-65dyne/cm at 25 deg.C and a viscosity of not higher than 15cp. Recording is made by depositing droplets of the ink on a material to be recorded, on which fibrous components of said material are exposed.