公开(公告)号：JP2546003B2

公开(公告)日：1996-10-23

申请号：JP33372189

申请日：1989-12-22

Applicant: TAKEDA CHEMICAL INDUSTRIES LTD

Inventor： UNEME HIDEKI ,  IWANAGA KOICHI ,  HIGUCHI NORIKO ,  MINAMIDA ISAO ,  OKAUCHI TETSUO

IPC: C07D277/20 ,  A01N47/44 ,  C07C279/36 ,  C07D213/53 ,  C07D277/32 ,  C07D277/34

公开(公告)号：JPH06247969A

公开(公告)日：1994-09-06

申请号：JP34570393

申请日：1993-12-22

Applicant: TAKEDA CHEMICAL INDUSTRIES LTD

Inventor： MINAMIDA ISAO ,  TABUCHI SATONORI ,  NAKAMURA SATOKO ,  TAKANOBU MASAHITO ,  OKAUCHI TETSUO

IPC: A01N43/90 ,  C07D471/04 ,  C07D487/04 ,  C07D498/04 ,  C07D513/04

Abstract: PURPOSE:To obtain a new compound useful as an agricultural and horticultural insecticide. CONSTITUTION:This compound is expressed by formula I {Q is condensed heterocyclic group having N in the bridgehead; R and R are H or 1-6C alkyl; (n) is 0-2; J is formula II or III [Ar is aryl or heterocyclic ring; R to R are H or 1-6C alkyl; R is H, 1-6C (halo)alkyl, etc.; R is H, (substituted)phenyl, naphthyl, furyl, etc.; X is O or S; R is H, 1-6C alkyl, etc.], etc.}, e.g. 1-(4- chlorophenylcarbamoyl)-3-(4-chlorophenyl)-4-(3-chloroimidazo[1,2-a]pyr idin-6-yl)-2- pyrazoline. The compound expressed by formula I is obtained by aminating a compound expressed by formula IV (Z is halogen or activated ester residue).

公开(公告)号：JPH06107510A

公开(公告)日：1994-04-19

申请号：JP13570793

申请日：1993-04-28

Applicant: TAKEDA CHEMICAL INDUSTRIES LTD

Inventor： KUWATSURU HIROO ,  IGARASHI REI ,  MINAMIDA ISAO

IPC: A01N47/44 ,  A01N51/00

Abstract: PURPOSE:To obtain a termite controlling agent, capable of manifesting its activity at a much lower concentration than that of a conventional controlling agent without causing problems in the environment, further residual functional activity against the termites and safely and advantageously usable in wooden buildings damaged by the termites. CONSTITUTION:The objective termite controlling agent comprises a compound of the formula (R is H, 1-6C alkylcarbonyl or 1-6C alkoxycarbonyl) or its salt. A compound in which R is H, acetyl group or methoxycarbonyl group in the compound of the formula is preferred. This compound is applied to a habitat of the termites, a site in fear of damaging with the termites or a site suffering from the damage of the termites to control or exterminate the termites.

公开(公告)号：JPH05345774A

公开(公告)日：1993-12-27

申请号：JP811693

申请日：1993-01-21

Applicant: TAKEDA CHEMICAL INDUSTRIES LTD

Inventor： MINAMIDA ISAO ,  IWANAGA KOICHI ,  OKAUCHI TETSUO

IPC: C07D213/61 ,  A01N33/18 ,  A01N35/08 ,  A01N43/40 ,  A01N43/42 ,  A01N43/60 ,  A01N43/78 ,  A01N47/24 ,  A01N55/00 ,  C07C211/22 ,  C07C211/29 ,  C07C229/34 ,  C07C243/10 ,  C07C311/50 ,  C07D20060101 ,  C07D213/24 ,  C07D213/38 ,  C07D213/40 ,  C07D213/42 ,  C07D213/64 ,  C07D213/70 ,  C07D213/74 ,  C07D213/77 ,  C07D215/12 ,  C07D215/38 ,  C07D239/26 ,  C07D241/12 ,  C07D277/20 ,  C07D277/22 ,  C07D277/28 ,  C07D277/32 ,  C07D277/38 ,  C07D277/42 ,  C07D295/13 ,  C07D295/30 ,  C07D401/06 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12 ,  C07D403/14 ,  C07D413/12 ,  C07D413/14 ,  C07D417/12 ,  C07D417/14 ,  C07F7/08

Abstract: PURPOSE:To obtain a new compound useful as a synthetic intermediate for new alpha-unsaturated amines having insecticidal and acaricidal action as an agricultural chemical. CONSTITUTION:The compound of formula I (Hal is halogen; R is group through H, C, N or O; HN-R is phthalimide), e.g. 2-chloro-5-thiazolylmethylamine. The compound of formula I is obtained by reacting formula II (one of X and X is electron attracting group and the other is H or electron attracting group; R is 1-4C alkyl or aralkyl) with a compound of formula III (Y is H or alkali metal; A is 2-halogeno-5-thiazolyl) and reacting the resultant compound of formula IV with a compound of the formula R -Y.

公开(公告)号：JPH0459763A

公开(公告)日：1992-02-26

申请号：JP16759990

申请日：1990-06-25

Applicant: TAKEDA CHEMICAL INDUSTRIES LTD

Inventor： UNEME HIDEKI ,  HIGUCHI NORIKO ,  MINAMIDA ISAO ,  OKAUCHI TETSUO

IPC: C07D277/28 ,  A01N47/44 ,  C07D213/74 ,  C07D521/00

Abstract: NEW MATERIAL:A compound expressed by formula I [R to R are H, nitro, hydrocarbon group or heterocyclic group and at least one of R and R is expressed by the formula -(CH2)n-R (R is heterocyclic group; n is 0 or 1); R , along with R and together with N, may represent cyclic amino; R is hydrocarbon group or heterocyclic group; X is electron attractive group] or salts thereof. EXAMPLE:2-(6-Chloro-3-pyridylmethyl)-1,1,3-trimethyl-3-nitroguanidine. USE:An insecticide, useful for controlling sanitary insect pests and animal or plant parasitic insects with low toxicity and excellent in safety. PREPARATION:A compound expressed by formula II is reacted with a compound expressed by the formula R -Y (Y is leaving group) in the presence of a base (e.g. sodium hydride) in a solvent such as DMF at -20 to +150 deg.C to afford the objective compound expressed by formula I.

公开(公告)号：JPS6011713B2

公开(公告)日：1985-03-27

申请号：JP10810176

申请日：1976-09-08

Applicant: TAKEDA CHEMICAL INDUSTRIES LTD

Inventor： NUMATA MITSUO ,  MINAMIDA ISAO ,  TSUSHIMA SUSUMU

IPC: A61K20060101 ,  A61K31/545 ,  A61K31/546 ,  A61P31/04 ,  C07D20060101 ,  C07D257/04 ,  C07D277/38 ,  C07D277/40 ,  C07D277/46 ,  C07D499/00 ,  C07D501/00 ,  C07D501/20 ,  C07D501/22 ,  C07D501/24 ,  C07D501/28 ,  C07D501/34 ,  C07D501/36 ,  C07D501/38 ,  C07D501/46 ,  C07D501/56 ,  C07D501/60

公开(公告)号：JPS5831357B2

公开(公告)日：1983-07-05

申请号：JP11620481

申请日：1981-07-23

Applicant: TAKEDA CHEMICAL INDUSTRIES LTD

Inventor： NUMATA MITSUO ,  MINAMIDA ISAO ,  YAMAOKA MASAYOSHI ,  MYAWAKI TOSHIO ,  SHIRAISHI MITSURU

IPC: C07D501/36 ,  A61K31/545 ,  A61K31/546 ,  A61P31/04

公开(公告)号：JPS5283871A

公开(公告)日：1977-07-13

申请号：JP127976

申请日：1976-01-01

Applicant: TAKEDA CHEMICAL INDUSTRIES LTD

Inventor： NUMATA MITSUO ,  MINAMIDA ISAO ,  YAMAOKA MASAYOSHI ,  SHIRAISHI MITSURU ,  MIYAWAKI TOSHIO

IPC: C07D501/20 ,  A61K31/545 ,  A61K31/546 ,  A61P31/04 ,  C07D501/22 ,  C07D501/34 ,  C07D501/36 ,  C07D501/46

Abstract: PURPOSE:7-[2-(2-Exo substd.-4-thiazolin-4-yl) acetamido]-cephalosporins of formula I [R is H, alkyl, acyl; X is O, S, NR (R is H, acyl, or alkyl that forms a ring structure together with R ); Y is H, acyloxy, alkoxy, quaternary ammonium, SR (R is N-containing hetero-ring)].

公开(公告)号：JPS5123289A

公开(公告)日：1976-02-24

申请号：JP3056275

申请日：1975-03-12

Applicant: TAKEDA CHEMICAL INDUSTRIES LTD

Inventor： NUMATA MITSUO ,  MINAMIDA ISAO ,  YAMAOKA MASAYOSHI ,  SHIRAISHI MITSURU ,  MYAWAKI TOSHIO

IPC: C07D501/20 ,  A61K31/545 ,  A61K31/546 ,  A61P31/04 ,  C07D501/06 ,  C07D501/22 ,  C07D501/26 ,  C07D501/28 ,  C07D501/36

公开(公告)号：DE69132821T2

公开(公告)日：2002-07-18

申请号：DE69132821

申请日：1991-08-15

Applicant: TAKEDA CHEMICAL INDUSTRIES LTD

Inventor： MINAMIDA ISAO ,  KANDO YASUYUKI ,  ISHIZUKA HITOSHI ,  OKAUCHI TETSUO ,  UNEME HIDEKI

IPC: A01N51/00 ,  A01N43/40 ,  A01N43/78 ,  A01N43/84 ,  A01N47/44 ,  C07C255/58 ,  C07C277/08 ,  C07C279/34 ,  C07C335/40 ,  C07D205/10 ,  C07D207/40 ,  C07D207/404 ,  C07D207/44 ,  C07D207/448 ,  C07D209/48 ,  C07D211/88 ,  C07D213/16 ,  C07D213/36 ,  C07D213/61 ,  C07D213/69 ,  C07D213/75 ,  C07D241/12 ,  C07D277/12 ,  C07D277/20 ,  C07D277/28 ,  C07D277/32 ,  C07D277/34 ,  C07D277/38 ,  C07D277/48 ,  C07D417/12

Abstract: Novel substituted nitroguanidine derivatives and salts thereof having the following formula: wherein R is a substituted or unsubstituted heterocyclic group; R is a group attached through a sulfur atom, a group attached through a phosphorus atom, cyano, -CO-OR wherein R is a substituted or unsubstituted hydrocarbon group or a substituted or unsubstituted heterocyclic group, or -CO-NR R wherein R and R , which are the same or different, are each independently hydrogen, a substituted or unsubstituted hydrocarbon group or a substituted or unsubstituted heterocyclic group, or R and R , taken together with the nitrogen atom to which they are attached are a cyclic amino group; R is hydrogen, a substituted or unsubstituted hydrocarbon group (except for one substituted with an oxo group at the binding site), a group attached through a sulfur atom, a group attached through a phosphorus atom, cyano, -CO-R wherein R is hydrogen, a substituted or unsubstituted hydrocarbon group or a substituted or unsubstituted heterocyclic group, -CO-OR wherein R is a substituted or unsubstituted hydrocarbon group or a substituted or unsubstituted heterocyclic group, or -CO-NR R wherein R and R , which are the same or different, are each independently hydrogen, a substituted or unsubstituted hydrocarbon group or a substituted or unsubstituted heterocyclic group, or R and R , taken together with the nitrogen is hydrogen or a lower alkyl group; which have unexpectedly potent pesticidal activity and very low toxicity.