公开(公告)号：US20160025637A1

公开(公告)日：2016-01-28

申请号：US14877411

申请日：2015-10-07

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Kurt J. Halverson ,  Raymond J. Kenney ,  Olester Benson, JR. ,  Raymond P. Johnston ,  Guoping Mao ,  Patrick R. Fleming ,  George Van Dyke Tiers ,  Naiyong Jing

IPC: G01N21/75 ,  G01N21/64 ,  G01N21/55 ,  G01N21/31

CPC classification number: G01N21/75 ,  B01L3/50853 ,  B01L2200/0689 ,  B01L2200/12 ,  B01L2300/044 ,  B01L2300/0654 ,  B01L2300/0819 ,  B01L2300/0822 ,  B01L2300/0851 ,  B01L2300/0887 ,  B29C35/0888 ,  B29C59/046 ,  B29C59/08 ,  B29C59/10 ,  B29C59/14 ,  B29C59/16 ,  B29C2035/0827 ,  B29C2059/023 ,  G01N21/03 ,  G01N21/253 ,  G01N21/31 ,  G01N21/55 ,  G01N21/6428 ,  G01N21/6452 ,  G01N2021/0346 ,  G01N2201/0446 ,  G01N2201/064 ,  G01N2201/08

Abstract: The disclosure provides microstructured articles and methods useful for detecting an analyte in a sample. The articles include microwell arrays. The articles can be used with an optical system component in methods to detect or characterize an analyte.

Abstract translation: 本公开提供了用于检测样品中的分析物的微结构化制品和方法。 文章包括微孔阵列。 在用于检测或表征分析物的方法中，物品可以与光学系统组件一起使用。

公开(公告)号：US09013702B2

公开(公告)日：2015-04-21

申请号：US13456467

申请日：2012-04-26

Applicant: Robert Freese ,  Christopher Michael Jones ,  David Perkins ,  Michael Simcock ,  William Soltmann

Inventor： Robert Freese ,  Christopher Michael Jones ,  David Perkins ,  Michael Simcock ,  William Soltmann

IPC: G01N21/00 ,  G01N21/59 ,  G06E3/00 ,  G01N21/31 ,  G01N21/85

CPC classification number: G01N21/59 ,  G01N21/31 ,  G01N21/85 ,  G01N2201/064 ,  G06E3/00 ,  G06E3/001

Abstract: Optical computing devices are disclosed. One optical computing device includes an electromagnetic radiation source that emits electromagnetic radiation into an optical train to optically interact with a sample and at least one integrated computational element, the sample being configured to generate optically interacted radiation. A sampling window is arranged adjacent the sample and configured to allow transmission of the electromagnetic radiation therethrough and has one or more surfaces that generate one or more stray signals. A first focal lens is arranged to receive the optically interacted radiation and the one or more stray signals and generate a primary focal point from the optically interacted radiation. A structural element defines a spatial aperture aligned with the primary focal point such that the optically interacted radiation is able to pass therethrough while transmission of the one or more stray signals is substantially blocked by the structural element.

公开(公告)号：US20150069223A1

公开(公告)日：2015-03-12

申请号：US14467199

申请日：2014-08-25

Applicant: Kenichi Yoshimura

Inventor： Kenichi Yoshimura

IPC: G01S17/02 ,  B60S1/08 ,  G02B6/26

CPC classification number: G01S17/026 ,  B60S1/0833 ,  B60S1/0837 ,  B60S1/0844 ,  G01N21/3554 ,  G01N21/43 ,  G01N21/4738 ,  G01N21/552 ,  G01N2021/3155 ,  G01N2021/9586 ,  G01N2201/0626 ,  G01N2201/0631 ,  G01N2201/0636 ,  G01N2201/064 ,  G02B5/04 ,  G02B6/26

Abstract: A light guide member for an object detection apparatus for detecting an object adhered on a light translucent member based on change of quantity of reflection light received from the light translucent member includes a detection face where light exits to the light translucent member and reflection light reflected from the light translucent member enters, the detection face including a detection area where a part of the reflection light to enter the detection unit passes through, and a non-detection area where remaining part of the reflection light not to enter the detection unit passes through; a first intervening member disposed on the detection face attachable to the light translucent member via the first intervening member; and a second intervening member disposed on the detection face attachable to the light translucent member via the second intervening member. The first intervening member has flexibility greater than flexibility of the second intervening member.

Abstract translation: 一种用于物体检测装置的导光部件，用于根据从光透光部件接收到的反射光量的变化来检测粘附在透光性部件上的物体，包括：光从光透过部件射出的检测面， 光透过部件进入检测面，检测面包括进入检测部的反射光的一部分的检测区域，以及不进入检测部的反射光的剩余部分的非检测区域通过; 第一中间构件，其经由所述第一居间构件设置在所述检测面上，所述第一居间构件可附接到所述光半透明构件; 以及第二中间构件，其经由所述第二居间构件设置在所述检测面上，所述检测面可附着到所述光半透明构件。 第一个居间成员的灵活性大于第二个居间成员的灵活性。

公开(公告)号：US08724107B2

公开(公告)日：2014-05-13

申请号：US13964802

申请日：2013-08-12

Applicant: Hach Company

Inventor： Perry A. Palumbo

IPC: G01N21/00

CPC classification number: G02B19/0076 ,  G01N15/06 ,  G01N21/01 ,  G01N21/53 ,  G01N33/18 ,  G01N2015/0693 ,  G01N2201/064 ,  G02B3/04 ,  G02B5/001 ,  G02B13/18 ,  G02B19/0028 ,  G02B19/008 ,  G02B26/0808 ,  G02B2003/0093 ,  Y10T29/49826

Abstract: One embodiment provides an annular optical device (100), comprising: an annular meso-optic (1) including an annulus (11) centered about an axis of revolution (A); and a secondary optical structure (2) substantially coaxial within the annulus (11) of the annular meso-optic (1), wherein the secondary optical structure (2) and the annular meso-optic (1) are separated by a media (12) comprising a media refractive index that is lower than a secondary optical structure refractive index, with the secondary optical structure (2) being configured to hold a specimen to be radiated by impinging electromagnetic radiation directed into the secondary optical structure (2) substantially along the axis of revolution (A), wherein re-directed radiation from the specimen is allowed into the annular meso-optic (1) by the secondary optical structure (2) if an angle of incidence of the re-directed radiation exceeds the angle of Total Internal Reflectance. Other embodiments are descried and claimed.

Abstract translation: 一个实施例提供了一种环形光学装置（100），包括：环形介质光学元件（1），其包括以旋转轴线（A）为中心的环形部分（11）; 以及在所述环形中视光学器件（1）的所述环形空间（11）内基本上同轴的次级光学结构（2），其中所述次级光学结构（2）和所述环形中视镜（1）由介质（12） ）包括低于二次光学结构折射率的介质折射率，其中所述次级光学结构（2）构造成通过基本上沿着所述第二光学结构（2）的入射入射到所述次级光学结构（2）中的电磁辐射来保持待辐射的样本 旋转轴（A），其中如果重新引导的辐射的入射角超过总和的角度，则来自试样的重新定向的辐射被第二光学结构（2）允许进入环形介质光学器件（1） 内部反射。 描述并要求保护其他实施例。

公开(公告)号：US08436320B2

公开(公告)日：2013-05-07

申请号：US12319924

申请日：2009-01-14

Applicant: Masayuki Yamada

Inventor： Masayuki Yamada

IPC: F21V9/16

CPC classification number: G01N21/474 ,  G01N21/01 ,  G01N21/6456 ,  G01N2021/6484 ,  G01N2201/064

Abstract: A fluorescence detecting apparatus includes: an excitation light emitter for emitting excitation light exciting a fluorescent material onto a measurement object; an illumination light emitter for emitting illumination light onto the measurement object; an image pickup device for sensing light from the measurement object; and a controller for controlling the image pickup device, the excitation light emitter, and the illumination light emitter. The excitation light is emitted from the excitation light emitter onto the measurement object to define an image pickup condition of the image pickup device, based on an image pickup result to be obtained by sensing light from the measurement object by the image pickup device. A light amount of the illumination light to be emitted from the illumination light emitter is set depending on the image pickup condition. The excitation light, and the illumination light of the set light amount are simultaneously emitted from the excitation light emitter and the illumination light emitter, to cause the image pickup device to sense light from the measurement object.

公开(公告)号：US20130100433A1

公开(公告)日：2013-04-25

申请号：US13654747

申请日：2012-10-18

Applicant: Postnova Analytics GmbH

Inventor： Diethelm Frose ,  Roland Welz

IPC: G01N21/51

CPC classification number: G01N21/51 ,  G01N21/53 ,  G01N30/74 ,  G01N2021/4711 ,  G01N2201/064

Abstract: An apparatus for measuring the light scattering properties of a sample in a liquid medium, wherein the liquid medium with the sample is illuminated by a laser beam in a measuring cell transversely to the direction of filling the liquid medium in the measuring cell or transversely to the flow direction of the liquid medium within the measuring cell, comprising a laser, a cylindrical measuring cell, a first inner aperture system, a second outer aperture system and at least two detectors, wherein the detectors are arranged outside of the second outer aperture system so that they collect the light scattered on the sample within set, different angle ranges, wherein the first inner aperture system and the second outer aperture system are formed and arranged circularly and concentrically around the axis of the measuring cell. Use of the apparatus and a method that makes use of the apparatus are also disclosed.

Abstract translation: 一种用于测量液体介质中的样品的光散射性质的装置，其中具有样品的液体介质通过横向于在测量池中填充液体介质的方向的横向于横向于测量单元的测量单元中的激光束照射 测量单元内的液体介质的流动方向，包括激光器，圆柱形测量单元，第一内孔系统，第二外孔系统和至少两个检测器，其中检测器布置在第二外孔系统的外侧，因此 它们收集在集合的不同角度范围内散射在样品上的光，其中第一内孔系统和第二外孔系统被形成并围绕测量池的轴线圆周且同心地布置。 还公开了使用该装置和使用该装置的方法。

公开(公告)号：US20110194104A1

公开(公告)日：2011-08-11

申请号：US13023078

申请日：2011-02-08

Applicant: Martina DAUB ,  Jochen Rupp

Inventor： Martina DAUB ,  Jochen Rupp

IPC: G01N21/01 ,  B23P11/00 ,  B23P17/00

CPC classification number: G01N21/645 ,  B01L3/5085 ,  B01L2200/026 ,  B01L2200/141 ,  B01L2300/0654 ,  G01N21/0303 ,  G01N2021/6463 ,  G01N2021/6482 ,  G01N2201/064

Abstract: A device and a method for optical parallel analysis of a sample arrangement. The device includes a system of sample areas provided on and/or in a front face of the carrier substrate for receiving a sample substance; a system of detector areas provided on and/or in a back face of the carrier substrate, each detector area being assigned to a corresponding sample area; and a system of optical devices, each optical system being assigned to a corresponding sample area and being designed in such a way that it deflects light beams, which the corresponding sample area in response to an optical excitation does not emit in the direction of a detector area assigned to it, in the direction of the detector area assigned to it and/or in the direction of a detector-free area on the back face of the carrier substrate.

Abstract translation: 用于样本布置的光学并行分析的装置和方法。 该装置包括：设置在载体基板的正面和/或前表面上的用于接收样品物质的样品区域系统; 设置在载体基板的背面和/或背面的检测器区域的系统，每个检测器区域被分配给相应的样品区域; 以及光学装置系统，每个光学系统被分配给对应的采样区域并且被设计成使得其偏转光束，所述光束响应于光学激发而不在检测器的方向上发射 分配给它的区域，分配给它的检测器区域的方向和/或在载体基板的背面上的无检测器区域的方向上。

公开(公告)号：US07961311B2

公开(公告)日：2011-06-14

申请号：US12810838

申请日：2008-12-24

Applicant: Amnon Weichselbaum ,  Jaime De La Zerda ,  Issakhar Regev

Inventor： Amnon Weichselbaum ,  Jaime De La Zerda ,  Issakhar Regev

IPC: G01N21/01

CPC classification number: G01N21/51 ,  G01N21/0303 ,  G01N33/493 ,  G01N2021/0382 ,  G01N2021/4769 ,  G01N2021/479 ,  G01N2021/513 ,  G01N2201/064

Abstract: System and method for detecting and counting bacteria suspended in a biological fluid by means of light scattering measurements is provided. In accordance with the method of the invention the level of signal to noise of the measured intensities of light scattered by a sample of the biological fluid is significantly enhanced for forwardly scattered light within a range of scattering angles which are smaller compared to a predefined maximal scattering angle. The system of the invention includes a cuvette adapted to contain a sample of the biological fluid whose sidewalls and windows are suitably constructed and arranged to significantly reduce the level of reflected light obscuring the scattering patterns measured within the range of scattering angles considered.

Abstract translation: 提供了通过光散射测量来检测和计数悬浮在生物流体中的细菌的系统和方法。 根据本发明的方法，在与预定的最大散射相比较小的散射角范围内的向前散射光显着增强了由生物流体样本散射的光的测量强度的信噪比水平 角度。 本发明的系统包括适于容纳生物流体的样本的比色皿，其侧壁和窗口被适当地构造和布置，以显着降低反射光的水平，遮蔽在所考虑的散射角度范围内测量的散射图案。

公开(公告)号：US20080144012A1

公开(公告)日：2008-06-19

申请号：US11956245

申请日：2007-12-13

Applicant: Alexander F. H. Goetz ,  Leonid G. Feldman ,  Thomas Ciupak ,  Robert J. Faus ,  Brian Curtiss

Inventor： Alexander F. H. Goetz ,  Leonid G. Feldman ,  Thomas Ciupak ,  Robert J. Faus ,  Brian Curtiss

IPC: G01N21/00 ,  G01J3/00

CPC classification number: G01N21/278 ,  G01J3/02 ,  G01J3/021 ,  G01J3/0232 ,  G01J3/0256 ,  G01J3/0262 ,  G01J3/0291 ,  G01J3/08 ,  G01J3/42 ,  G01N21/255 ,  G01N21/55 ,  G01N2021/8411 ,  G01N2201/0636 ,  G01N2201/064

Abstract: A system and method for optical spectroscopic measurements is described. One embodiment includes a measurement head for optical spectroscopic measurements, the measurement head comprising an illumination source configured to illuminate a sample, a collection optic configured to view the sample, and an internal reference, wherein the internal reference can be illuminated by the illumination source and viewed by the collection optic.

Abstract translation: 描述了用于光谱测量的系统和方法。 一个实施例包括用于光学光谱测量的测量头，测量头包括被配置为照亮样本的照明源，被配置为观察样本的收集光学器件和内部参考，其中内部参考可被照明源照亮，以及 由收集光学器件查看。

公开(公告)号：US20060055930A1

公开(公告)日：2006-03-16

申请号：US10535259

申请日：2003-10-30

Applicant: Kazunori Yamauchi

Inventor： Kazunori Yamauchi

IPC: G01J3/50

CPC classification number: G01N21/78 ,  G01N21/8483 ,  G01N2021/7759 ,  G01N2021/7773 ,  G01N2201/022 ,  G01N2201/0627 ,  G01N2201/064 ,  G01N2201/101

Abstract: A scanning mechanism 6 moves an optical head 5 relative to a mount plate 2 in a scan direction, and light emitting diodes 3A, 3B mounted on the optical head 5 emit their respective beams of measurement light along the scan direction and onto two color regions TP3, TP3, respectively, of an immunochromatographic test strip mounted on the mount plate 2. Photodiodes 4A, 4B mounted on the optical head 5 receive respective beams of reflected light from the two color regions TP3, TP3 perpendicularly to colored lines on the immunochromatographic test strip, thereby implementing simultaneous measurement of color intensities of the colored lines formed in the two color regions TP3, TP3 of the immunochromatographic test strip.

Abstract translation: 扫描机构6在扫描方向上相对于安装板2移动光学头5，并且安装在光学头5上的发光二极管3A，3B沿着扫描方向发射它们各自的测量光束，并且发射到两个颜色 分别安装在安装板2上的免疫层析试片的区域TP 3，TP 3。 安装在光学头5上的光电二极管4A，4B接收来自两个颜色区域TP 3，TP 3的反射光的垂直于免疫色谱测试条上的着色线的反射光束，从而实现形成的着色线的色强度的同时测量 在两个颜色区域TP 3，TP 3的免疫层析试片。