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公开(公告)号：JP6421821B2
公开(公告)日：2018-11-14
申请号：JP2016529343
申请日：2015-06-16
Applicant: コニカミノルタ株式会社
IPC: G01N21/64
CPC classification number: G01N21/6428 , G01N21/645 , G01N21/648 , G01N2021/6439 , G01N2021/6471 , G01N2201/0806
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公开(公告)号：JP2017227642A
公开(公告)日：2017-12-28
申请号：JP2017122899
申请日：2017-06-23
Applicant: タイゲン バイオサイエンス コーポレイション
Inventor： フン−ジェン カオ
IPC: G01N21/64
CPC classification number: G01N21/6428 , C12Q1/686 , G01N21/645 , G01N2021/6419 , G01N2021/6439 , G01N2021/6441 , G01N2201/0627 , G01N2201/0806
Abstract: 【課題】蛍光標識されている複数の検体を検出するための多重チャンネル蛍光検出システムを提供する。 【解決手段】多重チャンネル蛍光検出システム100は、光源120、光フィルタ装置130、二並列導光管140および検出器150を備えている。上記光源120は、励起光161をそれぞれが供給するための複数のサブ光源を備えている。上記複数のサブ光源は、選択的に作動または停止させられ得る複数の単色の発光ダイオード(LED)である。上記光源120は、重複しないように形成されている半値全幅(FWHM)の波長を有している複数の光を発する。上記複数のサブ光源の配置によって、特定の検体を検出するための精度が向上され、特定波長帯を有している光束が効率的に強められ(光束のうち全波長帯を強めることなく)、構造が単純化されており、製造コストが削減されている。 【選択図】図3
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公开(公告)号：JP2015049244A
公开(公告)日：2015-03-16
申请号：JP2014172229
申请日：2014-08-27
Applicant: エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft , F. Hoffmann-La Roche Ag , エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft
Inventor： WIETZORREK JOACHIM
IPC: G01N21/64
CPC classification number: C12Q1/686 , G01N21/253 , G01N21/6452 , G01N21/6486 , G01N2201/06146 , G01N2201/0806 , G02B3/00
Abstract: 【課題】生物学的液体の光測定のための装置、およびサンプル領域内の分析物の存在または量の同時測定のための方法を提供する。【解決手段】装置114は、間隔が隔てられた複数のサンプル領域116と、少なくとも1つの周波数を有する光を放射するように構成される光源118と、光結合システムを有するレンズシステム120と、を有し、光結合システムは、光源118と複数のサンプル領域116との間に配置され、光結合システムは、少なくとも1つのテレセントリック素子134および複数の光混合ロッド136を有し、各サンプル領域は、光混合ロッド136の少なくとも1つが割り当てられ、テレセントリック素子134は、光源118と複数のサンプル領域116との間に配置され、複数の光混合ロッド136は、各光混合ロッド136の狭い端部140が複数のサンプル領域116の方を向くようにテーパーが付される。【選択図】図1
Abstract translation: 要解决的问题：提供用于生物液体的光度测量的装置，以及同时测量样品区域中分析物的存在或量的方法。解决方案：装置114包括：多个间隔开的样品区域116; 适于发射具有至少一个频率的光的光源118; 以及包括光耦合系统的透镜系统120。 光耦合系统设置在光源118和多个样本区域116之间，并且具有至少一个远心元件134和多个光混合杆136.每个采样区域被分配至少一个光混合杆136 ，并且远心元件134设置在光源118和多个样本区域116之间。多个光混合杆136是锥形的，使得每个光混合杆136的窄端140面向多个样品区域116 。
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公开(公告)号：US20180011007A1
公开(公告)日：2018-01-11
申请号：US15638987
申请日：2017-06-30
Applicant: bluepoint medical GmbH & Co. KG
Inventor： Bernd LINDNER
CPC classification number: G01N21/1717 , G01J3/0205 , G01J3/0216 , G01J3/10 , G01J3/42 , G01J2003/102 , G01N21/256 , G01N21/314 , G01N33/0037 , G01N33/0042 , G01N2021/0106 , G01N2021/1704 , G01N2021/1736 , G01N2021/1742 , G01N2021/1748 , G01N2021/3155 , G01N2021/3181 , G01N2021/451 , G01N2201/0627 , G01N2201/0631 , G01N2201/0668 , G01N2201/0806 , G01N2201/1211 , G01N2201/1218 , G02B6/00 , G02B6/0068 , Y02A50/245
Abstract: An arrangement for measuring gas concentrations in a gas absorption method, wherein the arrangement includes a plurality of light sources, a measuring cell, at least one measuring receiver and an evaluation apparatus. The measuring cell has a narrow, longitudinally-extended beam path with an entrance-side opening diameter B and an absorption length L with L>B, wherein the measuring cell has a gas inlet and a gas outlet wherein a plurality of light sources of different wavelength spectra is grouped into a first light source group wherein an optical homogeniser is interposed between the first light source group and the measuring cell, wherein, in particular, the homogeniser is coupled to the light source group directly or via a common optical assembly.
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85.发明申请公开(公告)号：US20170370826A1
公开(公告)日：2017-12-28
申请号：US15631618
申请日：2017-06-23
Applicant: BioComp Instruments Inc.
Inventor： David Coombs
CPC classification number: G01N21/05 , G01N21/0303 , G01N2021/0193 , G01N2021/6482 , G01N2201/0627 , G01N2201/0806
Abstract: The flow cell of the present application simultaneously monitors and measures light absorbance and fluorescence of particles in a flowing liquid. The flow cell comprises a housing having a light input face, an absorbance output face and first and second emission output faces; a fluid flow section within the housing that comprises a bottom funnel through which fluid enters the flow cell, a core chamber into which fluid flows from the bottom funnel, and a top funnel into which fluid flows from the core chamber, wherein the bottom and top funnels each comprise a first end which extends at an angle to a second end that is wider in diameter than the first end, and said second end of each is adjacent to and aligned with the core chamber; and a center section within the housing center having a recess formed therein which houses the core chamber of the fluid flow section, wherein said center section comprises a first pair of opposing channels formed in the light input face and the absorbance output face, respectively, and a second pair of opposing channels formed in the first emission output face and the second emission output face and which are perpendicular to the first pair of opposing channels, and wherein the first pair of opposing channels and second pair of opposing channels are in communication with the core chamber. An apparatus comprising the flow cell is also provided.
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Patent Agency Ranking
公开(公告)号：US20170322401A1
公开(公告)日：2017-11-09
申请号：US15656877
申请日：2017-07-21
Applicant: Bio-Rad Laboratories, Inc.
Inventor： Denis Pristinski , David P. Stumbo
CPC classification number: G02B19/0028 , G01N15/1434 , G01N15/1459 , G01N21/645 , G01N35/08 , G01N2015/1006 , G01N2021/6478 , G01N2201/0806 , G02B6/0008 , G02B6/262 , G02B19/0076
Abstract: Detection system comprising an examination region, a one-piece optical element including a focusing portion to concentrate light received from the examination region and a guiding portion to homogenize light received from the focusing portion, and a detector configured to detect homogenized light received from the guiding portion.
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公开(公告)号：US09726606B2
公开(公告)日：2017-08-08
申请号：US15320099
申请日：2015-06-16
Applicant: Konica Minolta, Inc.
Inventor： Ichiro Fujiyo , Tetsuya Noda
IPC: G01N21/64
CPC classification number: G01N21/6428 , G01N21/645 , G01N21/648 , G01N2021/6439 , G01N2021/6471 , G01N2201/0806
Abstract: A detection device comprises a chip holder, a light source, a light-guide rod, a wavelength separation filter, and an optical sensor. Given the relationship between the angle of incidence and light intensity of fluorescence on a light reception surface of the optical sensor, the optical transmittance of the wavelength separation filter at the dominant wavelength of the rays of fluorescence incident on the light reception surface at a peak angle of incidence at which the light intensity is the highest is greater than the optical transmittance of the wavelength separation filter at the dominant wavelength of the rays of excitation light incident on the light reception surface at the peak angle of incidence and is higher than the optical transmittance of the wavelength separation filter at the dominant wavelength of the rays of fluorescence incident on the light reception surface at an angle of incidence of 0 DEG.
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公开(公告)号：US20160169808A1
公开(公告)日：2016-06-16
申请号：US14566708
申请日：2014-12-10
Applicant: Molecular Devices, LLC
Inventor： Josef J. Atzler , Michael Katzlinger , Georg Kronberger , Bernhard Schinwald
IPC: G01N21/76
CPC classification number: G01N21/76 , G01J3/02 , G01N21/15 , G01N21/253 , G01N21/763 , G01N27/223 , G01N35/028 , G01N2021/015 , G01N2021/155 , G01N2035/1025 , G01N2201/0225 , G01N2201/0245 , G01N2201/0446 , G01N2201/0806
Abstract: In a sample analyzing apparatus, an injector assembly injects a reagent onto a sample, and luminescent light from the sample is transmitted to a detector. The assembly may be movable toward and away from the sample. The assembly may include one or more needles that communicate with one or more reservoirs supplying reagent or other liquids. The assembly may include a light guide for communicating with the detector. A cartridge may be provided in which the assembly, one or more reservoirs, and one or more pumps are disposed. The cartridge and/or the apparatus may be configured for enabling rinsing or priming to be done outside the apparatus. The cartridge and/or the apparatus may include one or more types of sensors configured for detecting, for example, the presence of liquid or bubbles in one or more locations of the apparatus and/or the cartridge.
Abstract translation: 在样品分析装置中，注射器组件将试剂注射到样品上，并将来自样品的发光发射到检测器。 组件可以朝向和远离样品移动。 组件可以包括与供应试剂或其它液体的一个或多个储存器连通的一个或多个针。 组件可以包括用于与检测器通信的光导。 可以提供盒，其中设置组件，一个或多个储存器和一个或多个泵。 墨盒和/或设备可以被配置为使得能够在设备外进行冲洗或启动。 药筒和/或装置可以包括一种或多种类型的传感器，其被配置用于例如在装置和/或药筒的一个或多个位置中检测液体或气泡的存在。
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公开(公告)号：US09115395B2
公开(公告)日：2015-08-25
申请号：US14471346
申请日：2014-08-28
Applicant: Roche Molecular Systems, Inc.
Inventor： Joachim Wietzorrek
CPC classification number: C12Q1/686 , G01N21/253 , G01N21/6452 , G01N21/6486 , G01N2201/06146 , G01N2201/0806 , G02B3/00
Abstract: An apparatus for photometric measurement of biological liquids and a method of simultaneously measuring the presence or quantity of an analyte in a sample region are disclosed. The apparatus includes a plurality of spaced apart sample regions; a light source adapted to emit light including at least one frequency; a lens system including a light coupling system, wherein the light coupling system is disposed between the light source and the plurality of sample regions. A method is also disclosed including illuminating the sample region with a light beam emitted from a light source, wherein said light beam passes a light coupling system, the light coupling system including a telecentric element and a plurality of light mixing rods, wherein the light coupling system is disposed between the light source and the sample region such that the light beam is directed into the sample region.
Abstract translation: 公开了一种生物液体光度测量装置和同时测量样品区域中分析物的存在或量的方法。 该装置包括多个间隔开的样品区域; 适于发射包括至少一个频率的光的光源; 包括光耦合系统的透镜系统，其中所述光耦合系统设置在所述光源和所述多个样本区域之间。 还公开了一种方法，其包括用从光源发射的光束照射样品区域，其中所述光束通过光耦合系统，所述光耦合系统包括远心元件和多个光混合棒，其中所述光耦合 系统设置在光源和样品区域之间，使得光束被引导到样品区域中。
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公开(公告)号：US20150064699A1
公开(公告)日：2015-03-05
申请号：US14471346
申请日：2014-08-28
Applicant: Roche Molecular Systems, Inc.
Inventor： Joachim Wietzorrek
CPC classification number: C12Q1/686 , G01N21/253 , G01N21/6452 , G01N21/6486 , G01N2201/06146 , G01N2201/0806 , G02B3/00
Abstract: An apparatus for photometric measurement of biological liquids and a method of simultaneously measuring the presence or quantity of an analyte in a sample region are disclosed. The apparatus includes a plurality of spaced apart sample regions; a light source adapted to emit light including at least one frequency; a lens system including a light coupling system, wherein the light coupling system is disposed between the light source and the plurality of sample regions. A method is also disclosed including illuminating the sample region with a light beam emitted from a light source, wherein said light beam passes a light coupling system, the light coupling system including a telecentric element and a plurality of light mixing rods, wherein the light coupling system is disposed between the light source and the sample region such that the light beam is directed into the sample region.
Abstract translation: 公开了一种生物液体光度测量装置和同时测量样品区域中分析物的存在或量的方法。 该装置包括多个间隔开的样品区域; 适于发射包括至少一个频率的光的光源; 包括光耦合系统的透镜系统，其中所述光耦合系统设置在所述光源和所述多个样本区域之间。 还公开了一种方法，其包括用从光源发射的光束照射样品区域，其中所述光束通过光耦合系统，所述光耦合系统包括远心元件和多个光混合棒，其中所述光耦合 系统设置在光源和样品区域之间，使得光束被引导到样品区域中。
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