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    FLOW CELL FOR A FLOW CYTOMETER SYSTEM
    1.
    发明申请
    FLOW CELL FOR A FLOW CYTOMETER SYSTEM 审中-公开
    流量计流量计系统

    公开(公告)号：WO2008058217A2

    公开(公告)日：2008-05-15

    申请号：PCT/US2007/083991

    申请日：2007-11-07

    Applicant: ACCURI INSTRUMENTS INC. ,  BAIR, Nathaniel, C. ,  RICH, A., Collin ,  EADIE, Mark, Robert ,  LEHRMANN, Rebecca, Ann

    Inventor： BAIR, Nathaniel, C. ,  RICH, A., Collin ,  EADIE, Mark, Robert ,  LEHRMANN, Rebecca, Ann

    IPC: C12M3/00

    CPC classification number: G01N15/1404 ,  G01N2015/1413 ,  Y10T29/49826 ,  Y10T137/0352 ,  Y10T137/0379 ,  Y10T137/0419 ,  Y10T436/115831 ,  Y10T436/117497

    Abstract: The flow cytometer system of the preferred embodiment includes a flow cell body that functions to contain, protect, and align the components of the flow cytometer system; a flow channel, coupled to the flow cell body, that functions to conduct and focus sample fluid through an interrogation zone; and a sample injection probe, removably coupled to the flow cell body, that functions to provide a uniform flow of sample fluid to the flow channel. The flow cytometer system is preferably designed for the flow cytometer field. The flow cytometer system, however, may be alternatively used in any suitable environment and for any suitable reason.

    Abstract translation: 优选实施例的流式细胞仪系统包括流动池主体，其用于容纳，保护和对准流式细胞仪系统的部件; 耦合到流动池主体的流动通道，其用于将样品流体引导和聚焦通过询问区; 以及可移除地耦合到流动池主体的样​​品注入探针，其用于提供样品流体到流动通道的均匀流动。 流式细胞仪系统优选设计用于流式细胞仪领域。 然而，流式细胞仪系统可以替代地在任何合适的环境中用于任何合适的原因。

    PULSATION ATTENUATOR FOR A FLUIDIC SYSTEM
    2.
    发明申请
    PULSATION ATTENUATOR FOR A FLUIDIC SYSTEM 审中-公开
    流体系统的脉冲衰减器

    公开(公告)号：WO2007067577A2

    公开(公告)日：2007-06-14

    申请号：PCT/US2006/046462

    申请日：2006-12-06

    Applicant: ACCURI INSTRUMENTS INC. ,  RICH, Collin, A. ,  MARTIN, Steven, M.

    Inventor： RICH, Collin, A. ,  MARTIN, Steven, M.

    IPC: F16L55/04

    CPC classification number: F15B1/021 ,  F04B43/12 ,  F15B1/10 ,  F15B21/008 ,  F15B2201/205 ,  F15B2201/215 ,  F15B2201/3151 ,  G01N15/1404 ,  Y10T137/3118 ,  Y10T137/7792

    Abstract: A pulsation attenuator for a fluidic system with a fluidic pump. The pulsation attenuator includes a fluidic channel, a first fluidic device adapted to attenuate pulsations with a shallow rolloff slope, and a second fluidic device adapted to attenuate pulsations with a shallow rolloff slope. The first fluidic device and the second fluidic device are connected to the fluidic channel such that they cooperatively attenuate pulsations with a steep rolloff slope. Preferably, the first fluidic device includes a first fluidic resistor and a first fluidic capacitor, and the second fluidic device includes a second fluidic resistor and a second fluidic capacitor. Preferably, the pulsation attenuator is arranged, similar a second-order low-pass filter, in the following order: (l) first fluidic resistor, (2) first fluidic capacitor, (3) second fluidic resistor, and (4) second fluidic capacitor.

    Abstract translation: 一种具有流体泵的流体系统的脉动衰减器。 脉动衰减器包括流体通道，适于衰减具有浅滚降斜率的脉动的第一流体装置，以及适于以浅滚降斜率衰减脉动的第二流体装置。 第一流体装置和第二流体装置连接到流体通道，使得它们以陡峭的滚降斜率协同地衰减脉动。 优选地，第一流体装置包括第一流体电阻器和第一流体电容器，并且第二流体装置包括第二流体电阻器和第二流体电容器。 优选地，按照以下顺序将脉动衰减器类似于二阶低通滤波器：（1）第一流体电阻器，（2）第一流体电容器，（3）第二流体电阻器，和（4）第二流体 电容。

    FLUIDIC SYSTEM FOR A FLOW CYTOMETER
    3.
    发明申请
    FLUIDIC SYSTEM FOR A FLOW CYTOMETER 审中-公开
    流量计流体系统

    公开(公告)号：WO2007103969A2

    公开(公告)日：2007-09-13

    申请号：PCT/US2007/063477

    申请日：2007-03-07

    Applicant: ACCURI INSTRUMENTS INC. ,  COLLIN, A., Rich

    Inventor： COLLIN, A., Rich

    IPC: G01N33/00

    CPC classification number: G01N15/1404 ,  G01N2015/1413 ,  G05D7/0682 ,  Y10T436/25375

    Abstract: The fluidic system of the preferred embodiment includes a sheath pump to pump sheath fluid from a sheath container into an interrogation zone and a waste pump to pump waste fluid from the interrogation zone into a waste container. The sheath pump and/or the waste pump draw sample fluid from a sample container into the interrogation zone. The fluidic system also includes a controller to adjust the flow rate of the sample fluid from the sample container into the interrogation zone. The fluidic system is preferably incorporated into a flow cytometer with a flow cell that includes the interrogation zone.

    Abstract translation: 优选实施例的流体系统包括护套泵，以将护套流体从护套容器泵送到询问区域，以及废物泵将废液从询问区泵送到废物容器中。 护套泵和/或废水泵将样品流体从样品容器中抽入询问区。 流体系统还包括控制器，用于调节样品流体从样品容器进入询问区域的流速。 流体系统优选地结合到具有包括询问区的流动池的流式细胞仪中。

    OPTICAL SYSTEM FOR A FLOW CYTOMETER
    4.
    发明申请
    OPTICAL SYSTEM FOR A FLOW CYTOMETER 审中-公开
    流量计的光学系统

    公开(公告)号：WO2007100723A2

    公开(公告)日：2007-09-07

    申请号：PCT/US2007/004836

    申请日：2007-02-22

    Applicant: ACCURI INSTRUMENTS INC. ,  RICH, Collin, A. ,  FISHER, Richard, L. ,  BAIR, Nathaniel, C.

    Inventor： RICH, Collin, A. ,  FISHER, Richard, L. ,  BAIR, Nathaniel, C.

    IPC: G01J3/02

    CPC classification number: G01N21/47 ,  G01N15/1436 ,  G01N15/1459 ,  G02B3/0037 ,  G02B3/04 ,  G02B3/06

    Abstract: The preferred embodiments of the invention is an optical system for a flow cytometer including a flow channel with an interrogation zone, and an illumination source that impinges the flow channel in the interrogation zone from a particular direction. The optical system preferably includes a lens system and a detection system. The lens system preferably includes multiple lens surfaces arranged along a plane perpendicular to the flow channel and adapted to collect and collimate light from the interrogation zone. The detection system preferably includes multiple detectors adapted to detect light from the lens system. Each detector preferably includes a local filter that independently filters for specific wavelengths. Thus, the user may easily swap the filters in any order to achieve the same detection parameters.

    Abstract translation: 本发明的优选实施例是用于流式细胞仪的光学系统，其包括具有询问区的流动通道，以及照射源，其将特定方向上的询问区中的流动通道入射。 光学系统优选地包括透镜系统和检测系统。 透镜系统优选地包括沿垂直于流动通道的平面布置的多个透镜表面，并且适于收集和准直来自询问区域的光。 检测系统优选地包括适于检测来自透镜系统的光的多个检测器。 每个检测器优选地包括独立地滤波特定波长的局部滤波器。 因此，用户可以以任何顺序容易地交换滤波器以实现相同的检测参数。

    FLUIDIC SYSTEM FOR A FLOW CYTOMETER
    6.
    发明公开
    FLUIDIC SYSTEM FOR A FLOW CYTOMETER 审中-公开
    流体系统用于流式细胞仪

    公开(公告)号：EP1991863A2

    公开(公告)日：2008-11-19

    申请号：EP07758065.2

    申请日：2007-03-07

    Applicant: Accuri Instruments Inc.

    Inventor： COLLIN, A., Rich

    IPC: G01N33/00

    CPC classification number: G01N15/1404 ,  G01N2015/1413 ,  G05D7/0682 ,  Y10T436/25375

    Abstract: The fluidic system of the preferred embodiment includes a sheath pump to pump sheath fluid from a sheath container into an interrogation zone and a waste pump to pump waste fluid from the interrogation zone into a waste container. The sheath pump and/or the waste pump draw sample fluid from a sample container into the interrogation zone. The fluidic system also includes a controller to adjust the flow rate of the sample fluid from the sample container into the interrogation zone. The fluidic system is preferably incorporated into a flow cytometer with a flow cell that includes the interrogation zone.

    OPTICAL SYSTEM FOR A FLOW CYTOMETER
    9.
    发明公开
    OPTICAL SYSTEM FOR A FLOW CYTOMETER 有权
    光学系统，将一河流式细胞仪

    公开(公告)号：EP1987389A2

    公开(公告)日：2008-11-05

    申请号：EP07751588.0

    申请日：2007-02-22

    Applicant: Accuri Instruments Inc.

    Inventor： RICH, Collin, A. ,  FISHER, Richard, L. ,  BAIR, Nathaniel, C.

    IPC: G02B27/14

    CPC classification number: G01N21/47 ,  G01N15/1436 ,  G01N15/1459 ,  G02B3/0037 ,  G02B3/04 ,  G02B3/06

    Abstract: The preferred embodiments of the invention is an optical system for a flow cytometer including a flow channel with an interrogation zone, and an illumination source that impinges the flow channel in the interrogation zone from a particular direction. The optical system preferably includes a lens system and a detection system. The lens system preferably includes multiple lens surfaces arranged along a plane perpendicular to the flow channel and adapted to collect and collimate light from the interrogation zone. The detection system preferably includes multiple detectors adapted to detect light from the lens system. Each detector preferably includes a local filter that independently filters for specific wavelengths. Thus, the user may easily swap the filters in any order to achieve the same detection parameters.

    PULSATION ATTENUATOR FOR A FLUIDIC SYSTEM
    10.
    发明公开
    PULSATION ATTENUATOR FOR A FLUIDIC SYSTEM 有权
    脉冲阻尼器的流体系统

    公开(公告)号：EP1957853A2

    公开(公告)日：2008-08-20

    申请号：EP06844858.8

    申请日：2006-12-06

    Applicant: Accuri Instruments Inc.

    Inventor： RICH, Collin, A. ,  MARTIN, Steven, M.

    IPC: F16L55/04

    CPC classification number: F15B1/021 ,  F04B43/12 ,  F15B1/10 ,  F15B21/008 ,  F15B2201/205 ,  F15B2201/215 ,  F15B2201/3151 ,  G01N15/1404 ,  Y10T137/3118 ,  Y10T137/7792

    Abstract: A pulsation attenuator for a fluidic system with a fluidic pump. The pulsation attenuator includes a fluidic channel, a first fluidic device adapted to attenuate pulsations with a shallow rolloff slope, and a second fluidic device adapted to attenuate pulsations with a shallow rolloff slope. The first fluidic device and the second fluidic device are connected to the fluidic channel such that they cooperatively attenuate pulsations with a steep rolloff slope. Preferably, the first fluidic device includes a first fluidic resistor and a first fluidic capacitor, and the second fluidic device includes a second fluidic resistor and a second fluidic capacitor. Preferably, the pulsation attenuator is arranged, similar a second-order low-pass filter, in the following order: (l) first fluidic resistor, (2) first fluidic capacitor, (3) second fluidic resistor, and (4) second fluidic capacitor.

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