公开(公告)号：WO2008058217A2

公开(公告)日：2008-05-15

申请号：PCT/US2007/083991

申请日：2007-11-07

Applicant: ACCURI INSTRUMENTS INC. ,  BAIR, Nathaniel, C. ,  RICH, A., Collin ,  EADIE, Mark, Robert ,  LEHRMANN, Rebecca, Ann

Inventor： BAIR, Nathaniel, C. ,  RICH, A., Collin ,  EADIE, Mark, Robert ,  LEHRMANN, Rebecca, Ann

IPC: C12M3/00

CPC classification number: G01N15/1404 ,  G01N2015/1413 ,  Y10T29/49826 ,  Y10T137/0352 ,  Y10T137/0379 ,  Y10T137/0419 ,  Y10T436/115831 ,  Y10T436/117497

Abstract: The flow cytometer system of the preferred embodiment includes a flow cell body that functions to contain, protect, and align the components of the flow cytometer system; a flow channel, coupled to the flow cell body, that functions to conduct and focus sample fluid through an interrogation zone; and a sample injection probe, removably coupled to the flow cell body, that functions to provide a uniform flow of sample fluid to the flow channel. The flow cytometer system is preferably designed for the flow cytometer field. The flow cytometer system, however, may be alternatively used in any suitable environment and for any suitable reason.

Abstract translation: 优选实施例的流式细胞仪系统包括流动池主体，其用于容纳，保护和对准流式细胞仪系统的部件; 耦合到流动池主体的流动通道，其用于将样品流体引导和聚焦通过询问区; 以及可移除地耦合到流动池主体的样​​品注入探针，其用于提供样品流体到流动通道的均匀流动。 流式细胞仪系统优选设计用于流式细胞仪领域。 然而，流式细胞仪系统可以替代地在任何合适的环境中用于任何合适的原因。

公开(公告)号：WO2007100723A2

公开(公告)日：2007-09-07

申请号：PCT/US2007/004836

申请日：2007-02-22

Applicant: ACCURI INSTRUMENTS INC. ,  RICH, Collin, A. ,  FISHER, Richard, L. ,  BAIR, Nathaniel, C.

Inventor： RICH, Collin, A. ,  FISHER, Richard, L. ,  BAIR, Nathaniel, C.

IPC: G01J3/02

CPC classification number: G01N21/47 ,  G01N15/1436 ,  G01N15/1459 ,  G02B3/0037 ,  G02B3/04 ,  G02B3/06

Abstract: The preferred embodiments of the invention is an optical system for a flow cytometer including a flow channel with an interrogation zone, and an illumination source that impinges the flow channel in the interrogation zone from a particular direction. The optical system preferably includes a lens system and a detection system. The lens system preferably includes multiple lens surfaces arranged along a plane perpendicular to the flow channel and adapted to collect and collimate light from the interrogation zone. The detection system preferably includes multiple detectors adapted to detect light from the lens system. Each detector preferably includes a local filter that independently filters for specific wavelengths. Thus, the user may easily swap the filters in any order to achieve the same detection parameters.

Abstract translation: 本发明的优选实施例是用于流式细胞仪的光学系统，其包括具有询问区的流动通道，以及照射源，其将特定方向上的询问区中的流动通道入射。 光学系统优选地包括透镜系统和检测系统。 透镜系统优选地包括沿垂直于流动通道的平面布置的多个透镜表面，并且适于收集和准直来自询问区域的光。 检测系统优选地包括适于检测来自透镜系统的光的多个检测器。 每个检测器优选地包括独立地滤波特定波长的局部滤波器。 因此，用户可以以任何顺序容易地交换滤波器以实现相同的检测参数。

公开(公告)号：EP1987389A2

公开(公告)日：2008-11-05

申请号：EP07751588.0

申请日：2007-02-22

Applicant: Accuri Instruments Inc.

Inventor： RICH, Collin, A. ,  FISHER, Richard, L. ,  BAIR, Nathaniel, C.

IPC: G02B27/14

CPC classification number: G01N21/47 ,  G01N15/1436 ,  G01N15/1459 ,  G02B3/0037 ,  G02B3/04 ,  G02B3/06

Abstract: The preferred embodiments of the invention is an optical system for a flow cytometer including a flow channel with an interrogation zone, and an illumination source that impinges the flow channel in the interrogation zone from a particular direction. The optical system preferably includes a lens system and a detection system. The lens system preferably includes multiple lens surfaces arranged along a plane perpendicular to the flow channel and adapted to collect and collimate light from the interrogation zone. The detection system preferably includes multiple detectors adapted to detect light from the lens system. Each detector preferably includes a local filter that independently filters for specific wavelengths. Thus, the user may easily swap the filters in any order to achieve the same detection parameters.

公开(公告)号：EP1987389B1

公开(公告)日：2017-06-14

申请号：EP07751588.0

申请日：2007-02-22

Applicant: Accuri Instruments Inc.

Inventor： RICH, Collin, A. ,  FISHER, Richard, L. ,  BAIR, Nathaniel, C.

IPC: G02B27/14 ,  G01N15/14

CPC classification number: G01N21/47 ,  G01N15/1436 ,  G01N15/1459 ,  G02B3/0037 ,  G02B3/04 ,  G02B3/06