公开(公告)号：US5920399A

公开(公告)日：1999-07-06

申请号：US820298

申请日：1997-03-18

Applicant: David R. Sandison ,  Mark R. Platzbecker ,  Timothy D. Vargo ,  Randal R. Lockhart ,  Michael R. Descour ,  Rebecca Richards-Kortum

Inventor： David R. Sandison ,  Mark R. Platzbecker ,  Timothy D. Vargo ,  Randal R. Lockhart ,  Michael R. Descour ,  Rebecca Richards-Kortum

IPC: A61B5/00 ,  G01J3/28 ,  G01N21/25 ,  F21K2/00 ,  G01J3/30 ,  G01N21/64

CPC classification number: A61B5/0084 ,  A61B5/0086 ,  A61B5/4331 ,  G01J3/2823

Abstract: A multispectral imaging method and apparatus adapted for use in determining material properties, especially properties characteristic of abnormal non-dermal cells. A target is illuminated with a narrow band light beam. The target expresses light in response to the excitation. The expressed light is collected and the target's response at specific response wavelengths to specific excitation wavelengths is measured. From the measured multispectral response the target's properties can be determined. A sealed, remote probe and robust components can be used for cervical imaging

Abstract translation: 适用于确定材料性质，特别是异常非真皮细胞性质特征的多光谱成像方法和装置。 用窄带光束照射目标。 目标响应激发表达光。 收集表达的光，并测量目标在特定响应波长对特定激发波长的响应。 从测量的多光谱响应可以确定目标的属性。 密封的远程探头和坚固的部件可用于颈部成像

公开(公告)号：US5838435A

公开(公告)日：1998-11-17

申请号：US953814

申请日：1997-10-20

Applicant: David R. Sandison

Inventor： David R. Sandison

IPC: G01J3/28 ,  G01J3/443 ,  G01J1/10 ,  G01N21/64

CPC classification number: G01J3/28 ,  G01J3/443 ,  G01J2003/2866

Abstract: Calibration spots of optically-characterized material placed in the field of view of a spectroscopic system allow calibration of the spectroscopic system. Response from the calibration spots is measured and used to calibrate for varying spectroscopic system operating parameters. The accurate calibration achieved allows quantitative spectroscopic analysis of responses taken at different times, different excitation conditions, and of different targets.

Abstract translation: 放置在光谱系统的视场中的光学表征材料的校准点允许校准光谱系统。 测量校准点的响应并用于校准不同的光谱系统操作参数。 实现的精确校准允许在不同时间，不同激发条件和不同目标下进行的响应的定量光谱分析。

公开(公告)号：US5929985A

公开(公告)日：1999-07-27

申请号：US820299

申请日：1997-03-18

Applicant: David R. Sandison ,  Mark R. Platzbecker ,  Michael R. Descour ,  David L. Armour ,  Marcus J. Craig ,  Rebecca Richards-Kortum

Inventor： David R. Sandison ,  Mark R. Platzbecker ,  Michael R. Descour ,  David L. Armour ,  Marcus J. Craig ,  Rebecca Richards-Kortum

IPC: G01J3/02 ,  G01J3/28 ,  G01J3/44 ,  G01N21/31 ,  G01N21/63

CPC classification number: G01N21/31 ,  G01J3/02 ,  G01J3/0218 ,  G01J3/0235 ,  G01J3/0291 ,  G01J3/44 ,  G01J3/2823 ,  G01J3/4406 ,  G01N2021/317 ,  G01N2201/0221 ,  G01N2201/0227

Abstract: A multispectral imaging probe delivers a range of wavelengths of excitation light to a target and collects a range of expressed light wavelengths. The multispectral imaging probe is adapted for mobile use and use in confined spaces, and is sealed against the effects of hostile environments. The multispectral imaging probe comprises a housing that defines a sealed volume that is substantially sealed from the surrounding environment. A beam splitting device mounts within the sealed volume. Excitation light is directed to the beam splitting device, which directs the excitation light to a target. Expressed light from the target reaches the beam splitting device along a path coaxial with the path traveled by the excitation light from the beam splitting device to the target. The beam splitting device directs expressed light to a collection subsystem for delivery to a detector.

Abstract translation: 多光谱成像探针将一系列激发光的波长传送到目标，并收集一系列表达的光波长。 多光谱成像探头适用于移动使用并在密闭空间中使用，并且被密封以抵抗敌对环境的影响。 多光谱成像探针包括限定与周围环境基本密封的密封体积的壳体。 分束装置安装在密封体积内。 激发光被引导到分束装置，其将激发光引导到目标。 来自目标的表示光沿着与由分束装置到目标的激发光行进的路径同轴的路径到达分束装置。 分束装置将表示的光引导到收集子系统以传送到检测器。

公开(公告)号：US06255659B1

公开(公告)日：2001-07-03

申请号：US09113686

申请日：1998-07-10

Applicant: David R. Sandison

Inventor： David R. Sandison

IPC: G01T104

CPC classification number: G01J1/50

Abstract: A new class of ultraviolet dosimeters is made possible by exposing caged dye molecules, which generate a dye molecule on exposure to ultraviolet radiation, to an exterior environment. Applications include sunburn monitors, characterizing the UV exposure history of UV-sensitive materials, especially including structural plastics, and use in disposable ‘one-use’ optical equipment, especially medical devices.

Abstract translation: 通过将在紫外线辐射下产生染料分子的笼式染料分子暴露于外部环境，可以实现新类型的紫外线剂量计。 应用包括晒伤监视器，其特征在于紫外线敏感材料的紫外线曝光历史，特别是包括结构塑料，并且用于一次性“一次性”光学设备，特别是医疗装置。