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    LATERAL FLOW ASSAY AND DEVICE USING MAGNETIC PARTICLES
    1.
    发明申请
    LATERAL FLOW ASSAY AND DEVICE USING MAGNETIC PARTICLES 审中-公开
    横向流动测定和使用磁性颗粒的装置

    公开(公告)号：WO2007011936A2

    公开(公告)日：2007-01-25

    申请号：PCT/US2006027845

    申请日：2006-07-18

    Applicant: IDEXX LAB INC ,  CARPENTER CHARLES R ,  FARACE GIOSI ,  MACHENRY PAUL SCOTT ,  FOSTER BRIAN JOHN ,  ZIEBA MIROLEE BLUE

    Inventor： CARPENTER CHARLES R ,  FARACE GIOSI ,  MACHENRY PAUL SCOTT ,  FOSTER BRIAN JOHN ,  ZIEBA MIROLEE BLUE

    IPC: G01N33/50

    CPC classification number: G01N33/54333 ,  G01N33/558 ,  H01F1/0054

    Abstract: A complex including magnetic particle bound to a metal colloid. The complex may be part of a reagent for use in a method for determining analytes. The reagent may include a binding partner specific for an analyte. The reagent may further include a first label that is distinguishable from a second label that is used to detect the analyte. The reagent is used in kits and methods for detecting analytes in samples. The methods include immunoassay methods, including method where the first label is used to calibrate the assay.

    Abstract translation: 包含结合到金属胶体上的磁性颗粒的复合物。 该复合物可以是用于测定分析物的方法中的试剂的一部分。 该试剂可以包括对分析物特异的结合配偶体。 该试剂还可以包括与用于检测分析物的第二标签可区分的第一标签。 该试剂用于检测样品中分析物的试剂盒和方法。 这些方法包括免疫分析方法，包括使用第一个标记来校准分析的方法。

    LATERAL FLOW ASSAY USING CENTRIFUGAL FORCE
    2.
    发明申请
    LATERAL FLOW ASSAY USING CENTRIFUGAL FORCE 审中-公开
    横向流动测定使用离心力

    公开(公告)号：WO2009039239A2

    公开(公告)日：2009-03-26

    申请号：PCT/US2008076788

    申请日：2008-09-18

    Applicant: IDEXX LAB INC ,  CARPENTER CHARLES ,  FARACE GIOSI ,  FARRELL ROBERT ,  NASSIF KEITH

    Inventor： CARPENTER CHARLES ,  FARACE GIOSI ,  FARRELL ROBERT ,  NASSIF KEITH

    IPC: G01N33/543 ,  G01N33/52 ,  G01N33/558

    CPC classification number: G01N33/525 ,  G01N33/54366 ,  G01N33/558

    Abstract: An apparatus, device, and method for laterally moving or assisting in the lateral movement of at least one of a liquid sample and a reagent along a porous carrier matrix is disclosed. The method comprises contacting the matrix with the at least one of the sample and the reagent and exposing the at least one of a liquid sample and a reagent to a centrifugal force, thereby moving or assisting in the lateral movement of the at least one of a liquid sample and a reagent along the porous carrier matrix.

    Abstract translation: 公开了一种用于沿着多孔载体基质横向移动或辅助液体样本和试剂中的至少一个的横向移动的设备，装置和方法。 该方法包括使基质与样品和试剂中的至少一种接触，并将液体样品和试剂中的至少一种暴露于离心力，从而移动或帮助使至少一种液体样品和试剂的横向运动 液体样品和沿多孔载体基质的试剂。

    IN-SITU EQUILIBRIUM DIALYSIS
    5.
    发明申请
    IN-SITU EQUILIBRIUM DIALYSIS 审中-公开
    现场平衡透析

    公开(公告)号：WO2007137120A1

    公开(公告)日：2007-11-29

    申请号：PCT/US2007/069150

    申请日：2007-05-17

    Applicant: IDEXX LABORATORIES, INC. ,  CARPENTER, Charles, R. ,  FARACE, Giosi

    Inventor： CARPENTER, Charles, R. ,  FARACE, Giosi

    IPC: G01N33/53 ,  G01N33/541

    CPC classification number: G01N33/541

    Abstract: A method for the determination of analytes in samples using a pre-precipitated antibody complex. The complex includes an anti-analyte antibody and a secondary binding molecule that results in the precipitation of the antibody. Labeled-anal yte analog competes for binding sites on the complex with analyte in the sample. The presence or amount of the analyte in the sample can is determined by detecting the amount of the label associated with the complex. The pre-precipitated antibody complex may be preloaded with labeled-analyte analog.

    Abstract translation: 使用预沉淀抗体复合物测定样品中分析物的方法。 复合物包括抗分析物抗体和导致抗体沉淀的二级结合分子。 标记肛门模拟物与样品中分析物的复合物上的结合位点竞争。 通过检测与复合物相关的标签的量来确定样品中分析物的存在或量。 预沉淀抗体复合物可以用标记的分析物类似物预加载。

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