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    METHOD AND APPARATUS FOR COMPOSITE DRUG DELIVERY MEDICAL DEVICES
    1.
    发明申请
    METHOD AND APPARATUS FOR COMPOSITE DRUG DELIVERY MEDICAL DEVICES 审中-公开
    用于复合药物递送医疗装置的方法和装置

    公开(公告)号：WO2009020607A3

    公开(公告)日：2009-04-16

    申请号：PCT/US2008009423

    申请日：2008-08-06

    Applicant: ARSENAL MEDICAL INC ,  ZUGATES GREG ,  DEWITT DAVID M ,  KENDALE AMAR ,  GITLIN IRINA ,  CARBECK JEFFREY

    Inventor： ZUGATES GREG ,  DEWITT DAVID M ,  KENDALE AMAR ,  GITLIN IRINA ,  CARBECK JEFFREY

    IPC: A61K9/00 ,  A61L29/16 ,  A61L31/16

    CPC classification number: A61K9/0024 ,  A61K9/70 ,  A61L27/54 ,  A61L2300/604

    Abstract: A medical device and method for drug delivery employing a 3 -dimensional pattern of a polymer support material (e.g., that is degradable after implant in a body), a drug associated with the polymer support material, and an adhesive that adheres the polymer support material and associated drug to body tissue. The adhesive may persist to maintain the device in a suitable position for a suitable time (e.g., until after the polymer support material begins to degrade to release the drug), and the drug may be arranged in discrete areas of the 3- dimensional pattern that are separated from each other. The pattern may be produced in whole or in part before deployment at a body site, or may be produced in whole or in part directly at a tissue surface.

    Abstract translation: 用于药物递送的医疗装置和方法，其使用聚合物支持材料的3维图案（例如，在植入体内可降解的），与聚合物支持材料相关联的药物和粘合聚合物支持材料的粘合剂 和相关药物与身体组织。 粘合剂可能持续以将装置保持在合适的位置达合适的时间（例如，直到聚合物支撑材料开始降解以释放药物之后），并且药物可以排列在三维图案的离散区域中， 彼此分离。 该图案可以在部署在身体部位之前全部或部分地产生，或者可以全部或部分地直接在组织表面处产生。

    IN SITU FORMING HEMOSTATIC FOAM IMPLANTS
    3.
    发明申请
    IN SITU FORMING HEMOSTATIC FOAM IMPLANTS 审中-公开
    在现场形成HEMOSTATIC泡沫植入物

    公开(公告)号：WO2012027138A1

    公开(公告)日：2012-03-01

    申请号：PCT/US2011/047615

    申请日：2011-08-12

    Applicant: ARSENAL MEDICAL, INC. ,  SHARMA, Upma ,  GITLIN, Irina ,  ZUGATES, Greg ,  RAGO, Adam ,  ZAMIRI, Parisa ,  BUSOLD, Rany ,  FREYMAN, Toby

    Inventor： SHARMA, Upma ,  GITLIN, Irina ,  ZUGATES, Greg ,  RAGO, Adam ,  ZAMIRI, Parisa ,  BUSOLD, Rany ,  FREYMAN, Toby

    IPC: A61B17/03

    CPC classification number: A61L24/043 ,  A61L24/0036 ,  A61L2400/06 ,  A61M31/002 ,  C08L75/04 ,  C08L71/02

    Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).

    Abstract translation: 通常描述与聚合物泡沫有关的系统和方法。 一些实施方案涉及用于制备聚合物泡沫的组合物和方法，以及使用聚合物泡沫体的方法。 聚合物泡沫可以施加到体腔并且与例如组织，损伤的组织，内部器官等接触。在一些实施例中，聚合物泡沫可以在体腔内形成（即，原位泡沫形成 ）。 此外，发泡聚合物可能能够在体腔的内表面上施加压力，并且能够防止或限制体液（例如血液等）的移动。

    METHOD AND APPARATUS FOR COMPOSITE DRUG DELIVERY MEDICAL DEVICES
    8.
    发明申请
    METHOD AND APPARATUS FOR COMPOSITE DRUG DELIVERY MEDICAL DEVICES 审中-公开
    用于复合药物递送医疗装置的方法和设备

    公开(公告)号：WO2009020607A2

    公开(公告)日：2009-02-12

    申请号：PCT/US2008/009423

    申请日：2008-08-06

    Applicant: ARSENAL MEDICAL, INC. ,  ZUGATES, Greg ,  DEWITT, David, M. ,  KENDALE, Amar ,  GITLIN, Irina ,  CARBECK, Jeffrey

    Inventor： ZUGATES, Greg ,  DEWITT, David, M. ,  KENDALE, Amar ,  GITLIN, Irina ,  CARBECK, Jeffrey

    IPC: A61K9/00 ,  A61L29/16 ,  A61L31/16

    CPC classification number: A61K9/0024 ,  A61K9/70 ,  A61L27/54 ,  A61L2300/604

    Abstract: A medical device and method for drug delivery employing a 3 -dimensional pattern of a polymer support material (e.g., that is degradable after implant in a body), a drug associated with the polymer support material, and an adhesive that adheres the polymer support material and associated drug to body tissue. The adhesive may persist to maintain the device in a suitable position for a suitable time (e.g., until after the polymer support material begins to degrade to release the drug), and the drug may be arranged in discrete areas of the 3- dimensional pattern that are separated from each other. The pattern may be produced in whole or in part before deployment at a body site, or may be produced in whole or in part directly at a tissue surface.

    Abstract translation: 用于使用聚合物载体材料（例如，植入体内后可降解的）的3维图案的药物递送的医疗装置和方法，与聚合物载体材料缔合的药物和 将聚合物载体材料和相关药物粘附到身体组织上的粘合剂。 粘合剂可以持续以将装置保持在合适的位置达合适的时间（例如，直到聚合物支撑材料开始降解以释放药物之后），并且药物可以布置在三维图案的离散区域中， 彼此分开。 图案可以在部署在身体部位之前全部或部分地产生，或者可以全部或部分直接在组织表面产生。

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