公开(公告)号：US20240181035A1

公开(公告)日：2024-06-06

申请号：US18285970

申请日：2022-04-08

Applicant: KAICO LTD. ,  KAGOSHIMA UNIVERSITY ,  KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION

Inventor： Kenta YAMATO ,  Takeshi MIYATA ,  Takahiro KUSAKABE ,  Jae Man LEE ,  Akitsu MASUDA

IPC: A61K39/12 ,  A61K35/64 ,  A61K39/00 ,  A61P31/20 ,  A61P37/04 ,  C12N15/86

CPC classification number: A61K39/12 ,  A61K35/64 ,  A61P31/20 ,  A61P37/04 ,  C12N15/86 ,  A61K2039/515 ,  A61K2039/542 ,  C12N2710/14022 ,  C12N2710/14034 ,  C12N2710/14043 ,  C12N2710/14052 ,  C12N2710/14071

Abstract: A method of easily producing an immunogenic pupa for oral administration and a pupa for oral administration produced by the method are provided. The method is a method of producing a pupa for oral administration, including a step of infecting a larva or pupa of an insect capable of being baculovirus-infected with a recombinant baculovirus having DNA encoding an antigen protein introduced therein and freeze-drying a pupa having pupated from the infected larva or the infected pupa.

公开(公告)号：MX2024014867A

公开(公告)日：2025-01-09

申请号：MX2024014867

申请日：2024-11-29

Applicant: KAICO LTD ,  UNIV KYUSHU NAT UNIV CORP

Inventor： YAMATO KENTA ,  TANIGUCHI MASAHIRO ,  NAKATAKE HIROKAZU ,  ESAKI KEIICHI ,  KUSAKABE TAKAHIRO

IPC: A61K39/00 ,  A61K9/19 ,  A61K35/64 ,  A61K38/02 ,  A61K39/39 ,  A61K48/00 ,  A61P11/00 ,  A61P13/12 ,  A61P17/00 ,  A61P31/20 ,  A61P37/04 ,  C07K14/01 ,  C12N7/00 ,  C12N15/34 ,  C12N15/86 ,  C12N15/866

Abstract: Una composición de vacuna oral contra enfermedades asociadas con el circovirus porcino, que comprende la pupa o célula de un insecto infeccioso por baculovirus, que se somete a un tratamiento de infección con un baculovirus recombinante, en el que se introduce ADN que codifica para la proteína de circovirus porcino tipo 2, y un tratamiento de liofilización.

公开(公告)号：AU2023280661A1

公开(公告)日：2025-01-02

申请号：AU2023280661

申请日：2023-06-02

Applicant: KAICO LTD ,  UNIV KYUSHU NAT UNIV CORP

Inventor： YAMATO KENTA ,  TANIGUCHI MASAHIRO ,  NAKATAKE HIROKAZU ,  ESAKI KEIICHI ,  KUSAKABE TAKAHIRO

IPC: A61K39/00 ,  A61K9/19 ,  A61K35/64 ,  A61K38/02 ,  A61K39/39 ,  A61K48/00 ,  A61P11/00 ,  A61P13/12 ,  A61P17/00 ,  A61P31/20 ,  A61P37/04 ,  C12N7/01 ,  C12N15/34 ,  C12N15/86 ,  C12N15/866

Abstract: An oral vaccine composition against a porcine circovirus-related disease, the oral vaccine composition comprising a pupa or a cell of a baculovirus infectious insect that has been subjected to an infection treatment with a recombinant baculovirus into which a DNA encoding a porcine circovirus type 2 protein has been introduced and subjected to a freeze-drying treatment.

公开(公告)号：EP4321020A1

公开(公告)日：2024-02-14

申请号：EP22784724.1

申请日：2022-04-08

Applicant: Kaico Ltd. ,  Kagoshima University ,  Kyushu University, National University Corporation

Inventor： YAMATO Kenta ,  MIYATA Takeshi ,  KUSAKABE Takahiro ,  LEE Jae Man ,  MASUDA Akitsu

IPC: A01K67/033 ,  A23L33/10 ,  A61K35/12 ,  A61K39/00 ,  A61K39/12 ,  A61P37/04 ,  C12N5/10 ,  C12N15/34 ,  C12N15/40 ,  C12N15/866

Abstract: A method of easily producing an immunogenic pupa for oral administration and a pupa for oral administration produced by the method are provided. The method is a method of producing a pupa for oral administration, including a step of infecting a larva or pupa of an insect capable of being baculovirus-infected with a recombinant baculovirus having DNA encoding an antigen protein introduced therein and freeze-drying a pupa having pupated from the infected larva or the infected pupa.

公开(公告)号：EP4534098A1

公开(公告)日：2025-04-09

申请号：EP23816164.0

申请日：2023-06-02

Applicant: Kaico Ltd. ,  Kyushu University, National University Corporation

Inventor： YAMATO, Kenta ,  TANIGUCHI, Masahiro ,  NAKATAKE, Hirokazu ,  ESAKI, Keiichi ,  KUSAKABE, Takahiro

IPC: A61K39/00 ,  A61K39/39 ,  A61K48/00 ,  A61P11/00 ,  A61P13/12 ,  A61P31/20 ,  A61P37/04 ,  A61P17/00 ,  A61K9/19 ,  C12N7/01 ,  C12N15/34 ,  C12N15/86 ,  C12N15/866 ,  A61K38/02 ,  A61K35/64

Abstract: An oral vaccine composition against porcine circovirus associated diseases, comprising the pupa or cell of a baculovirus infectious insect, which is subjected to an infection treatment with a recombinant baculovirus, into which porcine circovirus type 2 protein-encoding DNA is introduced, and a freeze-drying treatment.