Method and apparatus for disinfecting a water cooler reservoir
    7.
    发明授权
    Method and apparatus for disinfecting a water cooler reservoir 有权
    消毒水冷却器贮存器的方法和装置

    公开(公告)号:US06289690B1

    公开(公告)日:2001-09-18

    申请号:US09472320

    申请日:1999-12-23

    Inventor: Kenneth A. Davis

    Abstract: A method and apparatus for providing sanitized water in a bottled water dispenser uses a refrigeration system to cool the water and an ozone generating system to generate ozone for sanitizing the water. Ozone is generated and collected within an ozone generator housing. A blower transmits air to the housing, the air carrying the ozone through a flow line to an air diffuser that is positioned inside the reservoir of the water dispenser. A time deactivates the refrigeration system and at about the same time activates the ozone generator and the blower. The blower continues to pump air for a selected time period after the ozone generator is shut down, the water in the reservoir having been sanitized. This action dispenses any ozone odor. The pump then shuts off and the refrigeration system resumes operation of cooling the water in the reservoir.

    Abstract translation: 用于在瓶装饮水机中提供消毒水的方法和设备使用制冷系统来冷却水和臭氧发生系统以产生用于消毒水的臭氧。 臭氧产生并收集在臭氧发生器壳体内。 鼓风机将空气传递到壳体,空气通过流动线将臭氧携带到位于水分配器的储存器内的空气扩散器。 一段时间关闭制冷系统,同时激活臭氧发生器和鼓风机。 在臭氧发生器关闭之后,鼓风机继续抽吸空气一段时间,储存器中的水已经消毒。 这种作用会排除任何臭氧气味。 然后泵关闭,制冷系统恢复冷却储存器中的水的操作。

    Methods and reagents for quantitation of HLA-DR expression on peripheral blood cells
    8.
    发明授权
    Methods and reagents for quantitation of HLA-DR expression on peripheral blood cells 有权
    用于定量外周血细胞上HLA-DR表达的方法和试剂

    公开(公告)号:US06200766B1

    公开(公告)日:2001-03-13

    申请号:US09204860

    申请日:1998-12-03

    Inventor: Kenneth A. Davis

    CPC classification number: C07K16/2896 G01N33/56977 Y10S435/975 Y10S436/80

    Abstract: Improved methods, reagents, and kits for quantitation of HLA-DR expression on peripheral blood cells, particularly peripheral blood monocytes, are presented. Inclusion of a lysosomotropic amine, such as chloroquine, during staining stabilizes HLA-DR expression, and use of a novel anti-CD14 conjugate, anti-CD14-PerCP/CY5.5, permits the ready discrimination of monocytes. The improved methods, reagents, and kits may be used to assess immune competence, and to direct and monitor immunostimulatory therapies in septic patients exhibiting monocyte deactivation.

    Abstract translation: 提出了用于定量外周血细胞特别是外周血单核细胞上的HLA-DR表达的改进的方法,试剂和试剂盒。 在染色过程中包含溶酶体胺如氯喹可稳定HLA-DR表达,并且使用抗CD14结合物,抗-CD14-PerCP / CY5.5,可以快速鉴别单核细胞。 可以使用改进的方法,试剂和试剂盒来评估免疫能力,并且指导和监测显示单核细胞失活的脓毒症患者的免疫刺激疗法。

    Chromophores useful for the preparation of novel tandem conjugates
    9.
    发明授权
    Chromophores useful for the preparation of novel tandem conjugates 失效
    用于制备新型串联共轭物的发色团

    公开(公告)号:US6133429A

    公开(公告)日:2000-10-17

    申请号:US943491

    申请日:1997-10-03

    CPC classification number: G01N33/58 G01N33/532 G01N33/533 Y10S436/80

    Abstract: The inventors herein disclose new heterobifunctional chromophores that are capable of coupling with two distinct moieties. One moiety may be either a signal-enhancing agent or a blocking agent. The second moiety may be one member of a specific binding pair. The invention is based in part on the surprising result that when a chromophore is used as a "cross-linker" between a signal-enhancing agent and a member of a binding pair (essentially being buried between the two), the signal of the chromophore is not quenched. This arrangement, wherein the chromophore acts simultaneously as a cross-linker and a detectable compound, provides significant advantages over previously known compounds since the chromophore is sterically hindered from interacting non-specifically with substances present in the test systems. Moreover, the chromophore can be used as a cross-linker with little or no loss of detectable signal.

    Abstract translation: 本发明人在此公开了能够与两个不同部分偶联的新的异双功能发色团。 一个部分可以是信号增强剂或封闭剂。 第二部分可以是特异性结合对的一个成员。 本发明部分基于令人惊奇的结果,当发色团用作信号增强剂与结合对(基本上被埋在两者之间)的成员之间的“交联剂”时,发色团的信号 没有淬火。 这种布置,其中发色团作为交联剂和可检测化合物同时作用,提供了优于先前已知化合物的显着优点,因为发色团在空间上阻碍了非特异性地与测试系统中存在的物质相互作用。 此外,发色团可以用作交联剂,几乎没有或没有可检测信号的损失。

    Method and apparatus for sanitizing water dispensed from a water dispenser having a reservoir
    10.
    发明授权
    Method and apparatus for sanitizing water dispensed from a water dispenser having a reservoir 有权
    用于消毒从具有储存器的饮水机分配的水的方法和设备

    公开(公告)号:US08343341B2

    公开(公告)日:2013-01-01

    申请号:US13221448

    申请日:2011-08-30

    Abstract: A method and apparatus of sanitizing drinking water to be dispensed from a water dispenser having a reservoir includes the steps of providing the ozone gas generator that generates an ozone gas stream, transmitting the ozone gas stream from the generator to the water dispenser reservoir, mechanically breaking up the ozone gas stream inside the reservoir to produce ozone gas bubbles, and using the ozone gas bubbles to disinfect water in the reservoir. The ozone gas stream can be mechanically broken up using a pump such as, for example, an impeller type pump.

    Abstract translation: 从具有储存器的饮水机中分配饮用水的方法和装置包括以下步骤:提供产生臭氧气流的臭氧气体发生器,将来自发生器的臭氧气体流传递到水分配器储存器,机械破裂 使储存器内的臭氧气流产生臭氧气泡,并利用臭氧气泡对储层中的水进行消毒。 可以使用诸如叶轮式泵的泵机械地分解臭氧气体流。

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