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    SONICATION CARTRIDGE FOR NUCLEIC ACID EXTRACTION
    1.
    发明申请
    SONICATION CARTRIDGE FOR NUCLEIC ACID EXTRACTION 审中-公开
    用于核酸提取的透明胶囊

    公开(公告)号：WO2010138800A1

    公开(公告)日：2010-12-02

    申请号：PCT/US2010/036546

    申请日：2010-05-28

    Applicant: BIO-RAD LABORATORIES, INC. ,  SADRI, Amir M. ,  KIRCANSKI, Nenad ,  KIRCANSKI, Manja ,  NIKOLIC, Neven ,  TIMOTIJEVIC, Milija

    Inventor： SADRI, Amir M. ,  KIRCANSKI, Nenad ,  KIRCANSKI, Manja ,  NIKOLIC, Neven ,  TIMOTIJEVIC, Milija

    IPC: C12N13/00

    CPC classification number: C12N13/00

    Abstract: A cartridge in which sonication is applied to biological matter to disrupt and release nucleic acids from the matter is formed from a cartridge body containing a series of wells connected by fluid passages engineered to prevent backflow, with at least one well containing a sonication window covered by a thin lamina to transmit sonic vibrations from a sonication horn contacting the exterior surface of the window. Fluid transport among the wells is achieved by pressure differentials through the fluid passages, and a succession of functions is performed in the various wells, including disruption, mixing, binding of the released nucleic acids to binding materials, washing, elution, and collection.

    Abstract translation: 其中超声处理被应用于生物物质以破坏和释放核酸的盒由盒体形成，该盒体包含一系列通过工程设计以防止回流的流体通道连接的孔，其中至少一个孔包含超声处理窗口 一个薄层，从与窗户外表面接触的超声处理喇叭传播声音振动。 通过流体通道的压差来实现孔之间的流体输送，并且在各种孔中执行一系列功能，包括破坏，混合，释放的核酸与结合材料的结合，洗涤，洗脱和收集。

    SYSTEM AND METHOD FOR ULTRASONIC TRANSDUCER CONTROL
    3.
    发明申请
    SYSTEM AND METHOD FOR ULTRASONIC TRANSDUCER CONTROL 审中-公开
    超声波传感器控制系统与方法

    公开(公告)号：WO2012024631A1

    公开(公告)日：2012-02-23

    申请号：PCT/US2011/048494

    申请日：2011-08-19

    Applicant: BIO-RAD LABORATORIES, INC. ,  NIKOLIC, Neven ,  KIRCANSKI, Manja ,  KIRCANSKI, Nenad ,  SADRI, Amir M. ,  TIMOTIJEVIC, Milija ,  XU, Zhiliang

    Inventor： NIKOLIC, Neven ,  KIRCANSKI, Manja ,  KIRCANSKI, Nenad ,  SADRI, Amir M. ,  TIMOTIJEVIC, Milija ,  XU, Zhiliang

    IPC: H01L41/00

    CPC classification number: B06B1/0253 ,  H01L41/042

    Abstract: A system for controlling an ultrasonic transducer utilizes an indication of the relative phase of the voltage on the transducer and the current passing through the transducer to control the relative phase to a value that has been preselected to correspond to resonance of an electromechanical system that includes the ultrasonic transducer. In one example application, the system includes a waveform generator that produces an oscillating signal, and the frequency of the oscillating signal is adjustable under control of the control processor. The control processor adjusts the frequency of the oscillating signal according to a proportional control law at least some of the time, and according to a proportional-integral control law at least some of the time. The control processor may also control the amplitude of the oscillation of the ultrasonic transducer.

    Abstract translation: 用于控制超声波换能器的系统利用传感器上的电压和通过换能器的电流的相对相位的指示，以将相对相位控制为已经被预选为对应于机电系统的共振的值，该机电系统的谐振包括 超声波换能器。 在一个示例应用中，系统包括产生振荡信号的波形发生器，并且在控制处理器的控制下振荡信号的频率是可调节的。 控制处理器至少在一些时间根据比例控制规律调节振荡信号的频率，并且至少在一些时间根据比例积分控制律。 控制处理器还可以控制超声换能器的振荡幅度。

    MICRODOT PRINTING HEAD
    6.
    发明申请
    MICRODOT PRINTING HEAD 审中-公开
    MICRODOT印刷头

    公开(公告)号：WO2008109634A1

    公开(公告)日：2008-09-12

    申请号：PCT/US2008/055851

    申请日：2008-03-05

    Applicant: BIO-RAD LABORATORIES, INC. ,  SADRI, Amir ,  KIRCANSKI, Nenad

    Inventor： SADRI, Amir ,  KIRCANSKI, Nenad

    IPC: B01L3/02

    CPC classification number: B01L3/0251

    Abstract: A microdot printing head containing hollow pins as reservoirs for biological samples is manufactured with a high degree of accuracy in the spacing of the hollow pins by press fitting the pins into bushings at precisely dimensioned end sections in the bores of the bushings, and receiving the bushings into a common support block.

    Abstract translation: 包含中空销作为生物样品的储存器的微型打印头通过将销钉压配合到衬套的孔中的精确尺寸的端部的衬套中，以高精度地制造中空销的间隔，并且接收衬套 成为共同的支持块。

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