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    SPECIMEN HOLDER CAPABLE OF PERFORMING THREE-AXIS DRIVE FOR THREE-DIMENSIONAL ANALYSIS OF TRANSMISSION ELECTRON MICROSCOPE
    1.
    发明专利
    SPECIMEN HOLDER CAPABLE OF PERFORMING THREE-AXIS DRIVE FOR THREE-DIMENSIONAL ANALYSIS OF TRANSMISSION ELECTRON MICROSCOPE 审中-公开

    公开(公告)号：JP2012109115A

    公开(公告)日：2012-06-07

    申请号：JP2010256958

    申请日：2010-11-17

    Applicant: KOREA BASIC SCIENCE INST

    Inventor： KIM YANG-JUN ,  JUN JOHN-MAN

    IPC: H01J37/20 ,  F16H19/04 ,  F16H21/46

    Abstract: PROBLEM TO BE SOLVED: To provide a specimen holder capable of performing three-axis drive for three-dimensional analysis for a transmission electron microscope.SOLUTION: A specimen holder capable of performing three-axis drive for three-dimensional analysis for a transmission electron microscope can perform observation with high accuracy from more than three directions in order to analyze a single specimen or the complex internal structure. The specimen holder can rotate a cradle to support the specimen, and can three-dimensionally analyze the specimen more accurately by freely changing the direction of the specimen so that the cradle can move back and forth and from side to side.

    Method for detecting interaction of biopolymers
    2.
    发明专利
    Method for detecting interaction of biopolymers 有权
    检测生物聚合物相互作用的方法

    公开(公告)号：JP2010115192A

    公开(公告)日：2010-05-27

    申请号：JP2009198750

    申请日：2009-08-28

    Applicant: Korea Basic Science Inst ,  コリア・ベーシック・サイエンス・インスティテュート

    Inventor： LEE ZEE WON ,  KIM SOO HYUN

    IPC: C12Q1/02 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N15/09 ,  C12Q1/48 ,  C12Q1/68

    CPC classification number: G01N33/5035 ,  C07K2319/01 ,  C07K2319/60 ,  G01N33/542 ,  G01N33/557 ,  G01N33/582 ,  G01N33/6845

    Abstract: PROBLEM TO BE SOLVED: To provide a method for detecting interactions of biopolymers. SOLUTION: There are provided: a method for detection including (a) a step of preparing a cell comprising (i) a first construct comprising a bait, a first labeling material, and a translocation module and (ii) a second construct comprising a prey and a second labeling material, and (b) a step of detecting the distribution of the first construct and second construct in the cell; a method by which bindings and interactions occurring in a living cell can be detected in real time; and a method for screening a material that alters the binding and interaction thereof. COPYRIGHT: (C)2010,JPO&INPIT

    Abstract translation: 要解决的问题：提供一种检测生物聚合物相互作用的方法。 提供：一种用于检测的方法，包括（a）制备细胞的步骤，其包括（i）包含诱饵，第一标记材料和易位模块的第一构建体和（ii）第二构建体 包括猎物和第二标记材料，和（b）检测细胞中第一构建体和第二构建体的分布的步骤; 可以实时检测活细胞中发生的结合和相互作用的方法; 以及筛选改变其结合和相互作用的材料的方法。 版权所有（C）2010，JPO＆INPIT

    Moon grid specialized for three-dimensional observation by transmission electron microscope , and its manufacturing method
    3.
    发明专利
    Moon grid specialized for three-dimensional observation by transmission electron microscope , and its manufacturing method 有权
    用于通过传输电子显微镜进行三维观察的月经及其制造方法

    公开(公告)号：JP2009070806A

    公开(公告)日：2009-04-02

    申请号：JP2008164666

    申请日：2008-06-24

    Applicant: Korea Basic Science Inst ,  コリア ベーシック サイエンス インスティテュート

    Inventor： MOON WON JIN ,  PARK BYUNG KYU ,  KIM YOUNG-JUN ,  LEE JEE YOUNG ,  LEE SANG HEE ,  BAE DONG SIK

    IPC: H01J37/26 ,  G01N1/28

    CPC classification number: H01J37/20 ,  G01N23/046 ,  G01N2223/419 ,  H01J37/26 ,  H01J2237/20292 ,  H01J2237/204 ,  H01J2237/226 ,  H01J2237/2611 ,  H01J2237/2617

    Abstract: PROBLEM TO BE SOLVED: To provide a moon grid specialized for three-dimensional observation by a transmission electron microscope which can effectively obtain three-dimensional images without perfoming a separate mark-attachment process. SOLUTION: There is provided a moon grid 100 specialized for three-dimensional observation by a transmission electron microscope, and its manufacturing method, wherein the moon grid includes a sheet mesh 110 for protecting an upper structure, and a support film 120 equipped on the sheet mesh 110 and containing nanoparticles 130 dispersed. The moon grid 100 simplifies the conventional sample preparation process for three-dimensional observation, and allows for effective observation. The marks are provided before a sample is attached. As a result, in the case where the sample is an amorphous sample, a medical and biological sample, and a chemical sample, the grid, different from conventional grids, can solve a problem that the attachment of the marks is difficult and three-dimensional images can hardly be obtained in the conventional grids. COPYRIGHT: (C)2009,JPO&INPIT

    Abstract translation: 要解决的问题：提供专门用于通过透射电子显微镜进行三维观察的月球栅格，其能够有效地获得三维图像而不进行单独的标记附着过程。 解决方案：提供一种专用于通过透射电子显微镜进行三维观察的月球栅格100及其制造方法，其中月球包括用于保护上部结构的片状网眼110和装备有支撑膜120的支撑膜120 在片状网110上并包含分散的纳米颗粒130。 月球网100简化了用于三维观察的常规样品制备过程，并且允许有效观察。 标记在样品附着前提供。 结果，在样品是无定形样品，医用生物样品和化学样品的情况下，不同于常规网格的网格可以解决标记的附着困难和三维的问题 在传统格栅中难以获得图像。 版权所有（C）2009，JPO＆INPIT

    Method for signal improvement of fourier transform ion cyclotron resonance mass spectrograph
    4.
    发明专利
    Method for signal improvement of fourier transform ion cyclotron resonance mass spectrograph 有权
    FOURIER变换离子循环共振质谱信号改进方法

    公开(公告)号：JP2008117738A

    公开(公告)日：2008-05-22

    申请号：JP2006320747

    申请日：2006-11-28

    Applicant: Korea Basic Science Inst ,  コリア ベーシック サイエンス インスティテュート

    Inventor： KIM SUNG HWAN ,  CHOI MYOUNG CHOUL ,  YOO JONG SHIN ,  KIM HYUN SIK

    IPC: H01J49/38 ,  G01N27/62

    CPC classification number: H01J49/38

    Abstract: PROBLEM TO BE SOLVED: To provide a method of improving signals by changing voltage applied to an analysis trap of a high resolution Fourier transform ion cyclotron resonance mass spectrometer (FT-ICRMS) according to measurement stages, and in details, provide a method in which independent voltage different from a trap electrode is applied on an electrode added to the center part of the trap electrode after ions are activated and this is maintained until one measurement cycle is over.
    SOLUTION: When the method is applied, stability of ions confined in the trap becomes higher and a measured time region signal becomes longer. As for the time region signal that becomes longer, resolution and sensitivity of frequency or the region signal of a mass/charge ratio are enhanced.
    COPYRIGHT: (C)2008,JPO&INPIT

    Abstract translation: 要解决的问题：提供一种通过根据测量阶段改变施加到高分辨率傅里叶变换离子回旋共振质谱仪（FT-ICRMS）的分析阱的电压来改善信号的方法，并且具体地，提供一种 在离子被激活之后，在与陷阱电极的中心部分相加的电极上施加与捕获电极不同的独立电压的方法，直到一个测量周期结束。 解决方案：当应用该方法时，限制在阱中的离子的稳定性变得更高，并且测量的时间区域信号变得更长。 对于变长的时间区域信号，提高了频率的分辨率和灵敏度或质量/电荷比的区域信号。 版权所有（C）2008，JPO＆INPIT

    Hybrid ion transmitting device
    6.
    发明专利
    Hybrid ion transmitting device 审中-公开
    混合离子发射装置

    公开(公告)号：JP2008130534A

    公开(公告)日：2008-06-05

    申请号：JP2006320702

    申请日：2006-11-28

    Applicant: Korea Basic Science Inst ,  コリア ベーシック サイエンス インスティテュート

    Inventor： CHOI MYOUNG CHOUL ,  KIM HYUN SIK ,  KIM SUNG HWAN ,  YOO JONG SHIN

    IPC: H01J49/06 ,  G01N27/62 ,  H01J49/38

    CPC classification number: H01J49/063

    Abstract: PROBLEM TO BE SOLVED: To provide a hybrid ion transmitting device for enhancing transmission efficiency of an RF ion transmitting tube to which a gate valve is attached by using an electrostatic lens. SOLUTION: This hybrid ion transmitting device for enhancing detection sensitivity and resolution by using an electrostatic lens ion transmitting tube in the front, enabling use of a gate valve in the middle, and using an RF ion transmitting tube having good transmission efficiency in a high electric field in the back can be manufactured by combination of the electrostatic lens and the RF ion transmitting tube. That is, the hybrid ion transmitting device has a structure in which the electrostatic lens for transmitting injected ions and applying a voltage so that the ions can be focused on the center of the ion transmitting direction axis and the RF ion transmitting tube connected to the electrostatic lens to pass the ions focused on the center of the ion transmitting direction axis are connected through the gate valve. By this structure, the ion transmission efficiency is enhanced, and signal attenuation caused by collision with surrounding neutral gas is suppressed as much as possible by providing a stable vacuum state, and the hybrid ion transmitting device can enhance detection sensitivity and resolution thereby. COPYRIGHT: (C)2008,JPO&INPIT

    Abstract translation: 要解决的问题：提供一种用于通过使用静电透镜来提高安装有闸阀的RF离子传输管的传输效率的混合离子传输装置。 解决方案：该混合离子传输装置用于通过使用前面的静电透镜离子透射管来提高检测灵敏度和分辨率，从而能够使用中间的闸阀，并且使用具有良好传输效率的RF离子传输管 可以通过静电透镜和RF离子传输管的组合来制造背面的高电场。 也就是说，混合离子发射装置具有这样的结构，其中静电透镜用于传输注入的离子并施加电压，使得离子可以聚焦在离子传输方向轴的中心和连接到静电的RF离子传输管 透镜通过聚焦在离子传播方向轴中心的离子通过闸阀连接。 通过这种结构，离子传递效率提高，并且通过提供稳定的真空状态尽可能地抑制与周围中性气体的碰撞引起的信号衰减，并且混合离子发射装置可以提高检测灵敏度和分辨率。 版权所有（C）2008，JPO＆INPIT

    Probe unit for nuclear magnetic resonance
    7.
    发明专利
    Probe unit for nuclear magnetic resonance 有权
    核磁共振探测器

    公开(公告)号：JP2007232725A

    公开(公告)日：2007-09-13

    申请号：JP2007051602

    申请日：2007-03-01

    Applicant: Korea Basic Science Inst ,  韓國基礎科學支援研究院

    Inventor： HAN OC HEE ,  HAN KEE SUNG

    IPC: G01R33/34

    CPC classification number: G01R33/34046 ,  G01R33/30 ,  G01R33/307

    Abstract: PROBLEM TO BE SOLVED: To provide a probe unit for nuclear magnetic resonance for detecting characteristics and spatial distribution of a fluid with temporal variation.
    SOLUTION: The probe unit for nuclear magnetic resonance is disclosed. The probe unit includes an outer conductor of a cylinder type, a central conductor of a cylinder type disposed at the center inside the outer conductor, and a flow passage guiding a flow of a fluid outside the central conductor. A sense magnetic field in a radial direction is formed by applying an RF current between the outer conductor and the central conductor. Thus, the fluid flows along the flow passage, and characteristic variation due to reaction of the concurrently flowing fluid and variation of the spatial distribution of a fluid component with the lapse of time can be detected in real-time.
    COPYRIGHT: (C)2007,JPO&INPIT

    Abstract translation: 要解决的问题：提供用于检测具有时间变化的流体的特性和空间分布的用于核磁共振的探针单元。 解决方案：公开了用于核磁共振的探针单元。 探针单元包括圆筒型的外导体，设置在外导体内的中心的圆筒型中心导体，以及引导流体在中心导体外的流动通道。 通过在外部导体和中心导体之间施加RF电流来形成径向感测磁场。 因此，流体沿着流路流动，并且可以实时检测由于同时流动的流体的反应引起的特性变化和流体成分的空间分布随时间的变化。 版权所有（C）2007，JPO＆INPIT

    Relaxation oscillator using spin element
    8.
    发明专利
    Relaxation oscillator using spin element 审中-公开
    使用旋转元件的放松振荡器

    公开(公告)号：JP2010279008A

    公开(公告)日：2010-12-09

    申请号：JP2009173580

    申请日：2009-07-24

    Applicant: Korea Basic Science Inst ,  コリア ベーシック サイエンス インスティテュート

    Inventor： PARK SEUNG YOUNG ,  JO YOUNGHUN

    IPC: H03K3/59 ,  H01L29/82 ,  H01L43/08 ,  H03B15/00 ,  H03K3/02

    CPC classification number: H03K3/45 ,  H03B15/006

    Abstract: PROBLEM TO BE SOLVED: To provide a relaxation oscillator using a spin element.
    SOLUTION: A relaxation oscillator includes a power source for supplying power, a spin element driven by power supplied by the power source, and a capacitor connected to the spin element in parallel. The spin element has a variable voltage value which varies, depending on the intensity of a magnetic field. The capacitor discharges when the spin element has a minimum voltage value for a critical voltage range and charges, when the spin element has a maximum voltage value of the critical voltage range. Thus, the relaxation oscillator reduces the number of parts required for manufacture, simplifies circuits, and reduces manufacturing costs and power consumption. Consequently, the relaxation oscillator has effects that a wide range of frequency bands can be adjusted, a scope of activity is wide, and a high output is attained by using magnetization inversion.
    COPYRIGHT: (C)2011,JPO&INPIT

    Abstract translation: 要解决的问题：提供使用自旋元件的张弛振荡器。 解决方案：弛豫振荡器包括用于供电的电源，由电源提供的电力驱动的自旋元件和并联连接到该自旋元件的电容器。 自旋元件具有根据磁场的强度而变化的可变电压值。 当自旋元件具有临界电压范围的最大电压值时，当自旋元件具有临界电压范围的最小电压值和电荷时，电容器放电。 因此，张弛振荡器减少了制造所需的部件数量，简化了电路，并且降低了制造成本和功耗。 因此，张弛振荡器具有可以调节宽范围的频带，活动范围宽，并且通过使用磁化反转获得高输出的效果。 版权所有（C）2011，JPO＆INPIT

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