公开(公告)号：WO2007067577A3

公开(公告)日：2008-01-17

申请号：PCT/US2006046462

申请日：2006-12-06

Applicant: ACCURI INSTR INC ,  RICH COLLIN A ,  MARTIN STEVEN M

Inventor： RICH COLLIN A ,  MARTIN STEVEN M

IPC: F16L55/04

CPC classification number: F15B1/021 ,  F04B43/12 ,  F15B1/10 ,  F15B21/008 ,  F15B2201/205 ,  F15B2201/215 ,  F15B2201/3151 ,  G01N15/1404 ,  Y10T137/3118 ,  Y10T137/7792

Abstract: A pulsation attenuator for a fluidic system with a fluidic pump. The pulsation attenuator includes a fluidic channel, a first fluidic device adapted to attenuate pulsations with a shallow rolloff slope, and a second fluidic device adapted to attenuate pulsations with a shallow rolloff slope. The first fluidic device and the second fluidic device are connected to the fluidic channel such that they cooperatively attenuate pulsations with a steep rolloff slope. Preferably, the first fluidic device includes a first fluidic resistor and a first fluidic capacitor, and the second fluidic device includes a second fluidic resistor and a second fluidic capacitor. Preferably, the pulsation attenuator is arranged, similar a second-order low-pass filter, in the following order: (l) first fluidic resistor, (2) first fluidic capacitor, (3) second fluidic resistor, and (4) second fluidic capacitor.

Abstract translation: 一种具有流体泵的流体系统的脉动衰减器。 脉动衰减器包括流体通道，适于衰减具有浅滚降斜率的脉动的第一流体装置，以及适于以浅滚降斜率衰减脉动的第二流体装置。 第一流体装置和第二流体装置连接到流体通道，使得它们以陡峭的滚降斜率协同地衰减脉动。 优选地，第一流体装置包括第一流体电阻器和第一流体电容器，并且第二流体装置包括第二流体电阻器和第二流体电容器。 优选地，按照以下顺序将脉动衰减器类似于二阶低通滤波器：（1）第一流体电阻器，（2）第一流体电容器，（3）第二流体电阻器，和（4）第二流体电阻器 电容。

公开(公告)号：WO2004059316A1

公开(公告)日：2004-07-15

申请号：PCT/US2003/040335

申请日：2003-12-17

Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN ,  MARTIN, Steven, M. ,  OLSSON, Roy, H., III ,  BROWN, Richard, B. ,  FRANKLIN, Robert, K.

Inventor： MARTIN, Steven, M. ,  OLSSON, Roy, H., III ,  BROWN, Richard, B. ,  FRANKLIN, Robert, K.

IPC: G01N33/49

CPC classification number: B01L3/5027 ,  B01L2300/0645 ,  B01L2300/0883 ,  B01L2400/0406 ,  G01N27/06 ,  G01N27/07 ,  G01N27/22 ,  G01N27/226 ,  G01N33/4905 ,  Y10T436/2575

Abstract: A microsystem for determining clotting time of blood and a low-cost, single-use device for use therein are provided wherein the device has no moving parts or expensive optical sensors or magnets. The device includes a microfluidic channel and a microsensor at least partially in fluid communication with the channel. By analyzing changes in the sensor as a drop of blood flows down the microfluidic channel, the time at which the blood clots can be determined.

Abstract translation: 提供了一种用于确定血液凝固时间的微系统和用于其中的低成本，一次性使用的装置，其中该装置没有移动部件或昂贵的光学传感器或磁体。 该装置包括至少部分地与通道流体连通的微流体通道和微传感器。 通过将传感器的变化分析为微流体通道下降的血液流量，可以确定血块的时间。

公开(公告)号：WO2007067577A2

公开(公告)日：2007-06-14

申请号：PCT/US2006/046462

申请日：2006-12-06

Applicant: ACCURI INSTRUMENTS INC. ,  RICH, Collin, A. ,  MARTIN, Steven, M.

Inventor： RICH, Collin, A. ,  MARTIN, Steven, M.

IPC: F16L55/04

CPC classification number: F15B1/021 ,  F04B43/12 ,  F15B1/10 ,  F15B21/008 ,  F15B2201/205 ,  F15B2201/215 ,  F15B2201/3151 ,  G01N15/1404 ,  Y10T137/3118 ,  Y10T137/7792

Abstract: A pulsation attenuator for a fluidic system with a fluidic pump. The pulsation attenuator includes a fluidic channel, a first fluidic device adapted to attenuate pulsations with a shallow rolloff slope, and a second fluidic device adapted to attenuate pulsations with a shallow rolloff slope. The first fluidic device and the second fluidic device are connected to the fluidic channel such that they cooperatively attenuate pulsations with a steep rolloff slope. Preferably, the first fluidic device includes a first fluidic resistor and a first fluidic capacitor, and the second fluidic device includes a second fluidic resistor and a second fluidic capacitor. Preferably, the pulsation attenuator is arranged, similar a second-order low-pass filter, in the following order: (l) first fluidic resistor, (2) first fluidic capacitor, (3) second fluidic resistor, and (4) second fluidic capacitor.

Abstract translation: 一种具有流体泵的流体系统的脉动衰减器。 脉动衰减器包括流体通道，适于衰减具有浅滚降斜率的脉动的第一流体装置，以及适于以浅滚降斜率衰减脉动的第二流体装置。 第一流体装置和第二流体装置连接到流体通道，使得它们以陡峭的滚降斜率协同地衰减脉动。 优选地，第一流体装置包括第一流体电阻器和第一流体电容器，并且第二流体装置包括第二流体电阻器和第二流体电容器。 优选地，按照以下顺序将脉动衰减器类似于二阶低通滤波器：（1）第一流体电阻器，（2）第一流体电容器，（3）第二流体电阻器，和（4）第二流体 电容。