Abstract:
The present invention relates to the concept of a stress digital twin. The stress digital twin of an individual is a digital, i.e. computer-implemented system for monitoring a stress level of a living individual on the basis of at least data directly measured on the body of the living individual and by performing a thermodynamic evaluation of the stress entropic load. The stress entropic load is a thermodynamic parameter representing an amount of entropy generated within the living individual due to adaptation to a whole set of environmental influences in a given scenario at a given point of time. Based on a comparison with pre-collected reference data (library data), the invention triggers actions such as withdrawal or replacement of individuals acting in a given scenario or the issuing of alerts.
Abstract:
The present invention relates to the concept of a stress digital twin. The stress digital twin of an individual is a digital, i.e. computer-implemented system for monitoring a stress level of a living individual on the basis of at least data directly measured on the body of the living individual and by performing a thermodynamic evaluation of the stress entropic load. The stress entropic load is a thermodynamic parameter representing an amount of entropy generated within the living individual due to adaptation to a whole set of environmental influences in a given scenario at a given point of time. Based on a comparison with pre-collected reference data (library data), the invention triggers actions such as withdrawal or replacement of individuals acting in a given scenario or the issuing of alerts.
Abstract:
The resolution of conventional imaging devices is restricted by the diffraction limit. 'Perfect' imaging devices which can achieve a resolution beyond the diffraction limit have been considered impossible to implement. However, the present disclosure provides an imaging device which can achieve improved resolution beyond the diffraction limit and which can be implemented in practice. Said imaging device comprises: a. a lens having a refractive index that varies according to a predetermined refractive index profile; b. a source; c. an outlet for decoupling waves from the device; and d.a reflector provided around the lens, the source and the outlet, wherein the reflector and the refractive index profile of the lens are together arranged to direct waves transmitted in any of a plurality of directions from the source to the outlet.
Abstract:
The invention describes a method for the preparation of 2,3-dicarboxypolysaccharides with adjustable molecular weight, optionally modified by biologically active ligands, and their application as anticancer drug carriers. Anticancer drugs are based on transition metals, particularly on the bidentate -bound complexes of platinum of a type R 2 Pt II X 2 , R 2 Pt IV X 2 L 2 , ruthenium complexes [Ru(aren)L x (PTA) y ], and monodentate-bound complexes of a type [R 3 Pt II X]Y.
Abstract:
R E S U M E N USO DE REDES NEURONALES ARTIFICIALES PARA LA DETECCIÓN DE LA FORMACIÓN DE PIEDRAS EN LOS RIÑONES Y PARA ESTABLECER SU COMPOSICIÓN, comprendiendo el análisis multivariado con Redes Neuronales Artificiales (ANN)a partir de una base de datos que comprende la utilización de entre 10 y 14 marcadores metabólicos presentes en la orina como parámetros de análisis, los cuales consisten en: Volumen de micción, pH, niveles de creatinina, ácido úrico, urea, sodio, potasio, cloruro, citrato, calcio, oxalato, magnesio, fosfato y proteinuria.
Abstract:
Procedimiento de caracterización y clasificación de cálculos renales, que comprende las siguientes etapas: (a) se toman una pluralidad de muestras de cálculos renales y se cortan para observar su interior, obteniendo una superficie lo más plana posible, (b) se aplica la técnica de Formación de Imágenes Hiperespectrales (HSI) obteniendo los espectros de los cálculos renales anteriormente cortados, seleccionando una pluralidad de Regiones de Interés (ROI) y analizando la imagen a través de Análisis de Componentes Principales (PCA) (c) se identifican las especies principales mediante Análisis de Factores (FA) (d) se identifican valores atípicos a través de Análisis de Componentes Principales (PCA) (e) se analizan los diferentes tipos de cálculos renales a través de un Análisis de Componentes Principales (PCA) (f) a los datos obtenidos del Análisis de Componentes Principales (PCA) se aplica la técnica de Redes Neuronales Artificiales (ANN) para su clasificación.
Abstract:
The resolution of conventional imaging devices is restricted by the diffraction limit. 'Perfect' imaging devices which can achieve a resolution beyond the diffraction limit have been considered impossible to implement. However, the present disclosure provides an imaging device which can achieve improved resolution beyond the diffraction limit and which can be implemented in practice. Said imaging device comprises: a. a lens having a refractive index that varies according to a predetermined refractive index profile; b. a source; c. an outlet for decoupling waves from the device; and d.a reflector provided around the lens, the source and the outlet, wherein the reflector and the refractive index profile of the lens are together arranged to direct waves transmitted in any of a plurality of directions from the source to the outlet.