Abstract:
The invention relates to a method for improving soft tissue attachment comprising the steps of coating a surface of a material, to which surface soft tissue is to be attached, with a coating rich in TiO2 and/or SiO2, and applying said coating wherein soft tissue attachment is desired. The invention further relates to an implant wherein a surface or surfaces of said implant intended to be attached to soft tissue are coated with a porous coating rich in TiO2 and/or SiO2. The invention also relates to the use of a porous surface coating rich in TiO2, SiO2, or TiO2 and SiO2, for the manufacture of an implant for soft tissue attachment to said coating.
Abstract:
The present invention relates to a method for preparing controllably biodegradable silica fibres. The method comprises spinning the fibres from a silica sol, the viscosity of the sol being controlled. Further, the present invention relates to controllably biodegradable silica fibres prepared according to the invention and methods for controlling the biodegradability of the fibres. The invention also relates to controllably biodegradable fibres as sustained and/or controlled release delivery devices for biologically active agents, and to pharmaceutical preparations comprising such devices.
Abstract:
The present invention relates to an implant comprising a source of oxygen capable of releasing oxygen in the form of molecular oxygen or reactive oxygen species, and a material selected from the group consisting of biodegradable and/or bioactive glass, sol-gel produced silica and mixtures thereof. The invention also relates to the uses of the implant as well as to methods of making it.
Abstract:
An object of the invention is a method for at least partially treating biologically active sols, gels, mixtures or composites of sols and gels, and/or sol-gel derived materials, said sols, gels, mixtures or composites of sols and gels, and/or sol-gel derived materials comprising OH-groups and being at least partially amorphous, the said treatment being performed with a localised electromagnetic and/or acoustic energy. Other objects of the invention are a method for coating a device with biologically active sols, gels, mixtures or composites of sols and gels, and/or sol-gel derived materials and a method for modifying the biological activity of biologically active sols, gels, mixtures or composites of sols and gels, and/or sol-gel derived materials. All these methods use treatment with localised electromagnetic and/or acoustic energy. The invention also relates to the use of said method for the fabrication of different devices and to the attachment of at least two devices.